CST complex subunit CTC1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ICD4_LEIDO

TriTrypDb:

LdBPK_230010.1 , LdCL_230005000 , LDHU3_23.0020

Length:

613

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ICD4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICD4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	210	214	PF00656	0.559
CLV_C14_Caspase3-7	252	256	PF00656	0.686
CLV_C14_Caspase3-7	444	448	PF00656	0.582
CLV_MEL_PAP_1	353	359	PF00089	0.413
CLV_NRD_NRD_1	145	147	PF00675	0.569
CLV_NRD_NRD_1	355	357	PF00675	0.426
CLV_NRD_NRD_1	538	540	PF00675	0.649
CLV_PCSK_KEX2_1	147	149	PF00082	0.574
CLV_PCSK_KEX2_1	355	357	PF00082	0.426
CLV_PCSK_KEX2_1	538	540	PF00082	0.649
CLV_PCSK_PC1ET2_1	147	149	PF00082	0.530
CLV_PCSK_SKI1_1	117	121	PF00082	0.551
CLV_PCSK_SKI1_1	137	141	PF00082	0.330
CLV_PCSK_SKI1_1	33	37	PF00082	0.703
CLV_Separin_Metazoa	352	356	PF03568	0.492
DEG_APCC_DBOX_1	116	124	PF00400	0.547
DEG_APCC_DBOX_1	355	363	PF00400	0.428
DEG_Nend_Nbox_1	1	3	PF02207	0.752
DEG_SPOP_SBC_1	587	591	PF00917	0.393
DOC_AGCK_PIF_1	495	500	PF00069	0.591
DOC_CYCLIN_RxL_1	52	61	PF00134	0.556
DOC_CYCLIN_yCln2_LP_2	149	155	PF00134	0.688
DOC_CYCLIN_yCln2_LP_2	363	369	PF00134	0.547
DOC_CYCLIN_yCln2_LP_2	465	471	PF00134	0.550
DOC_MAPK_gen_1	146	155	PF00069	0.491
DOC_MAPK_gen_1	212	222	PF00069	0.620
DOC_MAPK_gen_1	303	313	PF00069	0.674
DOC_MAPK_gen_1	355	362	PF00069	0.419
DOC_MAPK_MEF2A_6	146	155	PF00069	0.530
DOC_MAPK_MEF2A_6	324	333	PF00069	0.468
DOC_PP1_RVXF_1	50	56	PF00149	0.713
DOC_PP2B_LxvP_1	149	152	PF13499	0.674
DOC_PP2B_LxvP_1	465	468	PF13499	0.703
DOC_PP4_FxxP_1	423	426	PF00568	0.455
DOC_USP7_MATH_1	11	15	PF00917	0.693
DOC_USP7_MATH_1	278	282	PF00917	0.654
DOC_USP7_MATH_1	316	320	PF00917	0.675
DOC_USP7_MATH_1	445	449	PF00917	0.544
DOC_USP7_MATH_1	54	58	PF00917	0.605
DOC_USP7_MATH_1	587	591	PF00917	0.393
DOC_WW_Pin1_4	372	377	PF00397	0.651
DOC_WW_Pin1_4	476	481	PF00397	0.632
DOC_WW_Pin1_4	503	508	PF00397	0.523
LIG_14-3-3_CanoR_1	217	223	PF00244	0.519
LIG_14-3-3_CanoR_1	355	360	PF00244	0.414
LIG_14-3-3_CanoR_1	441	450	PF00244	0.510
LIG_BIR_III_2	554	558	PF00653	0.629
LIG_BIR_III_4	226	230	PF00653	0.454
LIG_BRCT_BRCA1_1	163	167	PF00533	0.661
LIG_BRCT_BRCA1_1	472	476	PF00533	0.657
LIG_BRCT_BRCA1_1	498	502	PF00533	0.581
LIG_BRCT_BRCA1_1	58	62	PF00533	0.579
LIG_BRCT_BRCA1_1	588	592	PF00533	0.556
LIG_Clathr_ClatBox_1	579	583	PF01394	0.505
LIG_FHA_1	155	161	PF00498	0.613
LIG_FHA_1	297	303	PF00498	0.643
LIG_FHA_1	385	391	PF00498	0.522
LIG_FHA_1	477	483	PF00498	0.620
LIG_FHA_1	503	509	PF00498	0.588
LIG_FHA_1	529	535	PF00498	0.490
LIG_FHA_1	551	557	PF00498	0.695
LIG_FHA_1	566	572	PF00498	0.447
LIG_FHA_1	574	580	PF00498	0.425
LIG_FHA_1	589	595	PF00498	0.363
LIG_FHA_2	250	256	PF00498	0.684
LIG_FHA_2	524	530	PF00498	0.531
LIG_FHA_2	94	100	PF00498	0.556
LIG_LIR_Apic_2	404	410	PF02991	0.616
LIG_LIR_Gen_1	138	145	PF02991	0.542
LIG_LIR_Gen_1	164	173	PF02991	0.691
LIG_LIR_Gen_1	216	227	PF02991	0.596
LIG_LIR_Gen_1	349	359	PF02991	0.489
LIG_LIR_Gen_1	589	600	PF02991	0.586
LIG_LIR_Gen_1	6	16	PF02991	0.540
LIG_LIR_Nem_3	138	143	PF02991	0.545
LIG_LIR_Nem_3	164	168	PF02991	0.661
LIG_LIR_Nem_3	216	222	PF02991	0.599
LIG_LIR_Nem_3	26	30	PF02991	0.747
LIG_LIR_Nem_3	349	354	PF02991	0.493
LIG_LIR_Nem_3	540	544	PF02991	0.706
LIG_LIR_Nem_3	548	552	PF02991	0.581
LIG_LIR_Nem_3	589	595	PF02991	0.577
LIG_LIR_Nem_3	6	12	PF02991	0.557
LIG_LIR_Nem_3	99	105	PF02991	0.615
LIG_Pex14_2	481	485	PF04695	0.472
LIG_Pex14_2	498	502	PF04695	0.325
LIG_REV1ctd_RIR_1	533	543	PF16727	0.659
LIG_SH2_CRK	9	13	PF00017	0.619
LIG_SH2_STAP1	135	139	PF00017	0.547
LIG_SH2_STAP1	274	278	PF00017	0.631
LIG_SH2_STAP1	67	71	PF00017	0.641
LIG_SH2_STAT3	7	10	PF00017	0.738
LIG_SH2_STAT5	135	138	PF00017	0.548
LIG_SH2_STAT5	16	19	PF00017	0.538
LIG_SH2_STAT5	245	248	PF00017	0.456
LIG_SH2_STAT5	30	33	PF00017	0.594
LIG_SH2_STAT5	350	353	PF00017	0.544
LIG_SH2_STAT5	478	481	PF00017	0.472
LIG_SH2_STAT5	551	554	PF00017	0.629
LIG_SH2_STAT5	7	10	PF00017	0.618
LIG_SH2_STAT5	71	74	PF00017	0.607
LIG_SH3_3	19	25	PF00018	0.691
LIG_SH3_3	342	348	PF00018	0.576
LIG_SUMO_SIM_par_1	151	157	PF11976	0.631
LIG_SUMO_SIM_par_1	364	370	PF11976	0.594
LIG_SUMO_SIM_par_1	467	474	PF11976	0.590
LIG_SUMO_SIM_par_1	593	598	PF11976	0.573
LIG_TRAF2_1	38	41	PF00917	0.559
LIG_TYR_ITIM	189	194	PF00017	0.684
LIG_WRC_WIRS_1	24	29	PF05994	0.748
MOD_CK1_1	100	106	PF00069	0.571
MOD_CK1_1	130	136	PF00069	0.565
MOD_CK1_1	14	20	PF00069	0.681
MOD_CK1_1	281	287	PF00069	0.693
MOD_CK1_1	346	352	PF00069	0.552
MOD_CK1_1	470	476	PF00069	0.629
MOD_CK1_1	501	507	PF00069	0.449
MOD_CK1_1	523	529	PF00069	0.536
MOD_CK1_1	545	551	PF00069	0.522
MOD_CK2_1	23	29	PF00069	0.752
MOD_CK2_1	346	352	PF00069	0.597
MOD_CK2_1	35	41	PF00069	0.551
MOD_CK2_1	93	99	PF00069	0.476
MOD_GlcNHglycan	102	105	PF01048	0.508
MOD_GlcNHglycan	209	212	PF01048	0.537
MOD_GlcNHglycan	235	238	PF01048	0.542
MOD_GlcNHglycan	282	286	PF01048	0.721
MOD_GlcNHglycan	345	348	PF01048	0.588
MOD_GlcNHglycan	443	446	PF01048	0.595
MOD_GlcNHglycan	447	450	PF01048	0.555
MOD_GSK3_1	207	214	PF00069	0.601
MOD_GSK3_1	334	341	PF00069	0.501
MOD_GSK3_1	435	442	PF00069	0.482
MOD_GSK3_1	467	474	PF00069	0.697
MOD_GSK3_1	498	505	PF00069	0.487
MOD_GSK3_1	54	61	PF00069	0.576
MOD_GSK3_1	561	568	PF00069	0.531
MOD_GSK3_1	93	100	PF00069	0.481
MOD_N-GLC_1	458	463	PF02516	0.643
MOD_N-GLC_2	19	21	PF02516	0.457
MOD_NEK2_1	112	117	PF00069	0.496
MOD_NEK2_1	201	206	PF00069	0.564
MOD_NEK2_1	338	343	PF00069	0.607
MOD_NEK2_1	367	372	PF00069	0.575
MOD_NEK2_1	471	476	PF00069	0.526
MOD_NEK2_1	498	503	PF00069	0.475
MOD_NEK2_1	58	63	PF00069	0.523
MOD_NEK2_1	586	591	PF00069	0.594
MOD_NEK2_1	593	598	PF00069	0.499
MOD_NEK2_2	573	578	PF00069	0.522
MOD_PIKK_1	595	601	PF00454	0.410
MOD_PK_1	127	133	PF00069	0.531
MOD_PK_1	97	103	PF00069	0.602
MOD_PKA_1	355	361	PF00069	0.414
MOD_PKA_2	161	167	PF00069	0.642
MOD_PKA_2	211	217	PF00069	0.539
MOD_PKA_2	302	308	PF00069	0.663
MOD_PKA_2	355	361	PF00069	0.414
MOD_Plk_1	127	133	PF00069	0.671
MOD_Plk_1	17	23	PF00069	0.620
MOD_Plk_1	281	287	PF00069	0.700
MOD_Plk_1	439	445	PF00069	0.598
MOD_Plk_1	565	571	PF00069	0.547
MOD_Plk_1	587	593	PF00069	0.608
MOD_Plk_4	130	136	PF00069	0.518
MOD_Plk_4	154	160	PF00069	0.672
MOD_Plk_4	218	224	PF00069	0.602
MOD_Plk_4	23	29	PF00069	0.616
MOD_Plk_4	3	9	PF00069	0.733
MOD_Plk_4	334	340	PF00069	0.581
MOD_Plk_4	346	352	PF00069	0.513
MOD_Plk_4	384	390	PF00069	0.429
MOD_Plk_4	471	477	PF00069	0.638
MOD_Plk_4	528	534	PF00069	0.465
MOD_Plk_4	566	572	PF00069	0.657
MOD_Plk_4	581	587	PF00069	0.413
MOD_Plk_4	588	594	PF00069	0.496
MOD_Plk_4	97	103	PF00069	0.602
MOD_ProDKin_1	372	378	PF00069	0.646
MOD_ProDKin_1	476	482	PF00069	0.629
MOD_ProDKin_1	503	509	PF00069	0.518
MOD_SUMO_for_1	169	172	PF00179	0.606
TRG_DiLeu_BaEn_1	566	571	PF01217	0.587
TRG_DiLeu_BaEn_2	587	593	PF01217	0.608
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.485
TRG_DiLeu_BaLyEn_6	504	509	PF01217	0.590
TRG_DiLeu_BaLyEn_6	575	580	PF01217	0.522
TRG_ENDOCYTIC_2	191	194	PF00928	0.678
TRG_ENDOCYTIC_2	350	353	PF00928	0.492
TRG_ENDOCYTIC_2	478	481	PF00928	0.616
TRG_ENDOCYTIC_2	541	544	PF00928	0.703
TRG_ENDOCYTIC_2	549	552	PF00928	0.579
TRG_ENDOCYTIC_2	9	12	PF00928	0.573
TRG_ER_diArg_1	145	148	PF00400	0.572
TRG_ER_diArg_1	298	301	PF00400	0.720
TRG_ER_diArg_1	354	356	PF00400	0.428
TRG_ER_diArg_1	537	539	PF00400	0.622
TRG_NLS_MonoExtC_3	145	150	PF00514	0.535
TRG_NLS_MonoExtN_4	146	151	PF00514	0.542
TRG_Pf-PMV_PEXEL_1	251	255	PF00026	0.687
TRG_Pf-PMV_PEXEL_1	578	583	PF00026	0.409

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HCL3	Leishmania braziliensis	60%	100%
A4I037	Leishmania infantum	98%	100%
E9AW00	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4QBH6	Leishmania major	84%	100%