Zf-LSD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8ICB8_LEIDO

TriTrypDb:

LdCL_220013500 , LDHU3_22.1050

Length:

214

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ICB8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICB8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	49	53	PF00656	0.557
CLV_C14_Caspase3-7	71	75	PF00656	0.533
CLV_NRD_NRD_1	2	4	PF00675	0.591
CLV_PCSK_KEX2_1	196	198	PF00082	0.698
CLV_PCSK_KEX2_1	2	4	PF00082	0.460
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.698
DEG_Nend_UBRbox_1	1	4	PF02207	0.467
DEG_SPOP_SBC_1	97	101	PF00917	0.613
DOC_PP1_RVXF_1	194	201	PF00149	0.654
DOC_USP7_MATH_1	107	111	PF00917	0.664
DOC_USP7_MATH_1	43	47	PF00917	0.727
DOC_USP7_MATH_1	72	76	PF00917	0.607
DOC_USP7_MATH_1	97	101	PF00917	0.619
DOC_USP7_UBL2_3	139	143	PF12436	0.669
LIG_14-3-3_CanoR_1	132	138	PF00244	0.520
LIG_14-3-3_CanoR_1	2	10	PF00244	0.550
LIG_14-3-3_CanoR_1	76	84	PF00244	0.733
LIG_FHA_1	173	179	PF00498	0.577
LIG_FHA_1	188	194	PF00498	0.569
LIG_FHA_1	208	214	PF00498	0.637
LIG_FHA_2	4	10	PF00498	0.565
LIG_LIR_Nem_3	90	94	PF02991	0.641
LIG_PTB_Apo_2	113	120	PF02174	0.483
LIG_PTB_Phospho_1	113	119	PF10480	0.483
LIG_SH2_CRK	94	98	PF00017	0.534
LIG_SH2_STAP1	55	59	PF00017	0.520
LIG_SH2_STAT3	55	58	PF00017	0.519
LIG_SH3_3	31	37	PF00018	0.735
LIG_SH3_3	81	87	PF00018	0.598
LIG_TRAF2_1	46	49	PF00917	0.701
MOD_CK1_1	159	165	PF00069	0.613
MOD_CK1_1	41	47	PF00069	0.657
MOD_CK1_1	75	81	PF00069	0.659
MOD_CK1_1	98	104	PF00069	0.585
MOD_CK2_1	3	9	PF00069	0.574
MOD_CK2_1	43	49	PF00069	0.745
MOD_GlcNHglycan	119	122	PF01048	0.672
MOD_GlcNHglycan	29	32	PF01048	0.654
MOD_GlcNHglycan	40	43	PF01048	0.784
MOD_GSK3_1	117	124	PF00069	0.680
MOD_GSK3_1	156	163	PF00069	0.557
MOD_N-GLC_1	115	120	PF02516	0.647
MOD_N-GLC_1	27	32	PF02516	0.708
MOD_NEK2_1	157	162	PF00069	0.594
MOD_PKA_2	75	81	PF00069	0.600
MOD_Plk_1	115	121	PF00069	0.611
MOD_Plk_4	181	187	PF00069	0.589
MOD_Plk_4	87	93	PF00069	0.571
MOD_SUMO_for_1	4	7	PF00179	0.571
MOD_SUMO_rev_2	74	83	PF00179	0.636
TRG_ENDOCYTIC_2	154	157	PF00928	0.620
TRG_ER_diArg_1	1	3	PF00400	0.488
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.541
TRG_Pf-PMV_PEXEL_1	126	130	PF00026	0.536
TRG_Pf-PMV_PEXEL_1	21	25	PF00026	0.666
TRG_Pf-PMV_PEXEL_1	57	61	PF00026	0.537

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6M2	Leptomonas seymouri	55%	100%
A0A0S4IY29	Bodo saltans	32%	100%
A0A1X0NT95	Trypanosomatidae	40%	100%
A0A3R7RDF2	Trypanosoma rangeli	34%	100%
A4HCD4	Leishmania braziliensis	73%	100%
A4HZV2	Leishmania infantum	99%	100%
C9ZSI6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
E9AVR4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%