MORN repeat-containing protein 5

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8ICB1_LEIDO

TriTrypDb:

LdBPK_221090.1 , LdCL_220018300 , LDHU3_22.1600

Length:

412

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8ICB1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8ICB1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	316	320	PF00656	0.741
CLV_NRD_NRD_1	17	19	PF00675	0.504
CLV_NRD_NRD_1	172	174	PF00675	0.670
CLV_NRD_NRD_1	187	189	PF00675	0.481
CLV_NRD_NRD_1	215	217	PF00675	0.581
CLV_NRD_NRD_1	283	285	PF00675	0.621
CLV_NRD_NRD_1	307	309	PF00675	0.819
CLV_PCSK_KEX2_1	17	19	PF00082	0.506
CLV_PCSK_KEX2_1	174	176	PF00082	0.678
CLV_PCSK_KEX2_1	187	189	PF00082	0.487
CLV_PCSK_KEX2_1	307	309	PF00082	0.819
CLV_PCSK_PC1ET2_1	174	176	PF00082	0.728
CLV_PCSK_SKI1_1	285	289	PF00082	0.577
DEG_Nend_UBRbox_2	1	3	PF02207	0.620
DOC_PP4_FxxP_1	98	101	PF00568	0.647
DOC_USP7_MATH_1	230	234	PF00917	0.751
DOC_USP7_MATH_1	302	306	PF00917	0.774
DOC_WW_Pin1_4	112	117	PF00397	0.684
DOC_WW_Pin1_4	226	231	PF00397	0.706
DOC_WW_Pin1_4	297	302	PF00397	0.734
DOC_WW_Pin1_4	50	55	PF00397	0.585
LIG_14-3-3_CanoR_1	24	28	PF00244	0.405
LIG_FHA_1	102	108	PF00498	0.718
LIG_FHA_1	341	347	PF00498	0.670
LIG_FHA_2	262	268	PF00498	0.720
LIG_FHA_2	353	359	PF00498	0.717
LIG_Integrin_RGD_1	81	83	PF01839	0.658
LIG_LIR_Gen_1	121	126	PF02991	0.711
LIG_LIR_Nem_3	121	125	PF02991	0.722
LIG_PCNA_yPIPBox_3	389	403	PF02747	0.710
LIG_REV1ctd_RIR_1	47	53	PF16727	0.521
LIG_SH2_CRK	19	23	PF00017	0.412
LIG_SH2_CRK	25	29	PF00017	0.359
LIG_SH2_STAT3	151	154	PF00017	0.430
LIG_SH2_STAT3	8	11	PF00017	0.551
LIG_SH2_STAT5	151	154	PF00017	0.411
LIG_SH2_STAT5	181	184	PF00017	0.601
LIG_SH2_STAT5	193	196	PF00017	0.650
LIG_SH2_STAT5	25	28	PF00017	0.292
LIG_SH2_STAT5	33	36	PF00017	0.332
LIG_SH2_STAT5	8	11	PF00017	0.474
LIG_SH3_3	196	202	PF00018	0.570
LIG_SH3_3	375	381	PF00018	0.669
LIG_SH3_3	406	412	PF00018	0.651
LIG_SUMO_SIM_par_1	114	121	PF11976	0.648
LIG_SUMO_SIM_par_1	322	331	PF11976	0.680
LIG_SUMO_SIM_par_1	394	400	PF11976	0.698
LIG_UBA3_1	212	217	PF00899	0.657
MOD_CDK_SPxxK_3	297	304	PF00069	0.683
MOD_CK1_1	105	111	PF00069	0.816
MOD_CK1_1	161	167	PF00069	0.717
MOD_CK2_1	159	165	PF00069	0.622
MOD_CK2_1	222	228	PF00069	0.793
MOD_Cter_Amidation	15	18	PF01082	0.601
MOD_GlcNHglycan	128	131	PF01048	0.758
MOD_GlcNHglycan	161	164	PF01048	0.696
MOD_GlcNHglycan	232	235	PF01048	0.734
MOD_GlcNHglycan	330	333	PF01048	0.708
MOD_GlcNHglycan	60	63	PF01048	0.732
MOD_GSK3_1	101	108	PF00069	0.722
MOD_GSK3_1	222	229	PF00069	0.767
MOD_GSK3_1	230	237	PF00069	0.749
MOD_GSK3_1	303	310	PF00069	0.743
MOD_NEK2_1	125	130	PF00069	0.725
MOD_NEK2_1	328	333	PF00069	0.686
MOD_PKA_1	174	180	PF00069	0.719
MOD_PKA_1	222	228	PF00069	0.719
MOD_PKA_1	307	313	PF00069	0.825
MOD_PKA_2	174	180	PF00069	0.719
MOD_PKA_2	23	29	PF00069	0.405
MOD_PKA_2	269	275	PF00069	0.565
MOD_PKA_2	303	309	PF00069	0.816
MOD_Plk_2-3	83	89	PF00069	0.668
MOD_Plk_4	174	180	PF00069	0.709
MOD_Plk_4	307	313	PF00069	0.734
MOD_ProDKin_1	112	118	PF00069	0.681
MOD_ProDKin_1	226	232	PF00069	0.706
MOD_ProDKin_1	297	303	PF00069	0.739
MOD_ProDKin_1	50	56	PF00069	0.591
MOD_SUMO_for_1	221	224	PF00179	0.686
MOD_SUMO_rev_2	282	287	PF00179	0.571
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.660
TRG_ENDOCYTIC_2	137	140	PF00928	0.376
TRG_ENDOCYTIC_2	19	22	PF00928	0.385
TRG_ER_diArg_1	17	19	PF00400	0.528
TRG_ER_diArg_1	187	189	PF00400	0.576
TRG_ER_diArg_1	307	309	PF00400	0.780
TRG_Pf-PMV_PEXEL_1	187	191	PF00026	0.579
TRG_Pf-PMV_PEXEL_1	394	399	PF00026	0.698
TRG_Pf-PMV_PEXEL_1	403	407	PF00026	0.421

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P808	Leptomonas seymouri	46%	100%
A4HCG8	Leishmania braziliensis	76%	99%
C9ZSP0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9AGZ7	Leishmania infantum	100%	100%
E9AVV9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QBM0	Leishmania major	92%	100%