LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IC86_LEIDO
TriTrypDb:
LdBPK_220160.1 , LdCL_220007700 , LDHU3_22.0430
Length:
841

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IC86
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IC86

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 530 534 PF00656 0.586
CLV_C14_Caspase3-7 540 544 PF00656 0.489
CLV_C14_Caspase3-7 720 724 PF00656 0.555
CLV_C14_Caspase3-7 809 813 PF00656 0.656
CLV_C14_Caspase3-7 825 829 PF00656 0.491
CLV_NRD_NRD_1 389 391 PF00675 0.462
CLV_NRD_NRD_1 58 60 PF00675 0.606
CLV_NRD_NRD_1 650 652 PF00675 0.657
CLV_NRD_NRD_1 658 660 PF00675 0.566
CLV_NRD_NRD_1 662 664 PF00675 0.434
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I3S2 Leptomonas seymouri 42% 94%
A0A422NSI7 Trypanosoma rangeli 27% 100%
A4HC78 Leishmania braziliensis 73% 100%
A4HZQ6 Leishmania infantum 99% 100%
C9ZSE8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 100%
E9AVL2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4QBW7 Leishmania major 91% 100%
V5BB53 Trypanosoma cruzi 27% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS