LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3Q8IC82_LEIDO
TriTrypDb:
LdCL_150010200 , LDHU3_15.0660
Length:
707

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IC82
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IC82

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 167 171 PF00656 0.656
CLV_C14_Caspase3-7 63 67 PF00656 0.672
CLV_C14_Caspase3-7 701 705 PF00656 0.537
CLV_NRD_NRD_1 237 239 PF00675 0.667
CLV_NRD_NRD_1 274 276 PF00675 0.555
CLV_NRD_NRD_1 329 331 PF00675 0.681
CLV_NRD_NRD_1 386 388 PF00675 0.574
CLV_NRD_NRD_1 44 46 PF00675 0.691
CLV_NRD_NRD_1 512 514 PF00675 0.569
CLV_NRD_NRD_1 547 549 PF00675 0.550
CLV_NRD_NRD_1 623 625 PF00675 0.533
CLV_NRD_NRD_1 653 655 PF00675 0.568
CLV_PCSK_FUR_1 329 333 PF00082 0.676
CLV_PCSK_KEX2_1 237 239 PF00082 0.667
CLV_PCSK_KEX2_1 274 276 PF00082 0.555
CLV_PCSK_KEX2_1 328 330 PF00082 0.692
CLV_PCSK_KEX2_1 331 333 PF00082 0.655
CLV_PCSK_KEX2_1 386 388 PF00082 0.574
CLV_PCSK_KEX2_1 512 514 PF00082 0.569
CLV_PCSK_KEX2_1 547 549 PF00082 0.550
CLV_PCSK_KEX2_1 623 625 PF00082 0.533
CLV_PCSK_KEX2_1 653 655 PF00082 0.568
CLV_PCSK_PC1ET2_1 328 330 PF00082 0.664
CLV_PCSK_PC1ET2_1 331 333 PF00082 0.631
CLV_PCSK_SKI1_1 317 321 PF00082 0.575
CLV_PCSK_SKI1_1 375 379 PF00082 0.606
CLV_PCSK_SKI1_1 433 437 PF00082 0.647
CLV_PCSK_SKI1_1 50 54 PF00082 0.715
DEG_Nend_Nbox_1 1 3 PF02207 0.735
DEG_SIAH_1 240 248 PF03145 0.602
DOC_ANK_TNKS_1 329 336 PF00023 0.494
DOC_CKS1_1 408 413 PF01111 0.554
DOC_CYCLIN_RxL_1 430 437 PF00134 0.643
DOC_CYCLIN_RxL_1 45 54 PF00134 0.716
DOC_CYCLIN_RxL_1 487 499 PF00134 0.564
DOC_MAPK_gen_1 137 144 PF00069 0.657
DOC_MAPK_gen_1 328 339 PF00069 0.693
DOC_MAPK_gen_1 488 497 PF00069 0.566
DOC_MAPK_gen_1 547 553 PF00069 0.548
DOC_MAPK_gen_1 560 570 PF00069 0.476
DOC_MAPK_gen_1 650 659 PF00069 0.559
DOC_PP4_FxxP_1 268 271 PF00568 0.636
DOC_USP7_MATH_1 149 153 PF00917 0.711
DOC_USP7_MATH_1 203 207 PF00917 0.673
DOC_USP7_MATH_1 222 226 PF00917 0.530
DOC_USP7_MATH_1 263 267 PF00917 0.588
DOC_USP7_MATH_1 279 283 PF00917 0.581
DOC_USP7_MATH_1 347 351 PF00917 0.547
DOC_USP7_MATH_1 39 43 PF00917 0.729
DOC_USP7_MATH_1 406 410 PF00917 0.509
DOC_USP7_MATH_1 412 416 PF00917 0.530
DOC_USP7_MATH_1 439 443 PF00917 0.640
DOC_USP7_MATH_1 48 52 PF00917 0.626
DOC_USP7_MATH_1 514 518 PF00917 0.630
DOC_USP7_MATH_1 584 588 PF00917 0.574
DOC_USP7_MATH_1 592 596 PF00917 0.615
DOC_WW_Pin1_4 152 157 PF00397 0.736
DOC_WW_Pin1_4 173 178 PF00397 0.603
DOC_WW_Pin1_4 190 195 PF00397 0.616
DOC_WW_Pin1_4 232 237 PF00397 0.707
DOC_WW_Pin1_4 269 274 PF00397 0.664
DOC_WW_Pin1_4 275 280 PF00397 0.643
DOC_WW_Pin1_4 284 289 PF00397 0.656
DOC_WW_Pin1_4 407 412 PF00397 0.672
LIG_14-3-3_CanoR_1 12 17 PF00244 0.714
LIG_14-3-3_CanoR_1 223 232 PF00244 0.687
LIG_14-3-3_CanoR_1 298 306 PF00244 0.579
LIG_14-3-3_CanoR_1 386 390 PF00244 0.654
LIG_14-3-3_CanoR_1 513 522 PF00244 0.583
LIG_14-3-3_CanoR_1 547 553 PF00244 0.513
LIG_14-3-3_CanoR_1 560 570 PF00244 0.476
LIG_Actin_WH2_2 570 588 PF00022 0.538
LIG_BRCT_BRCA1_1 264 268 PF00533 0.637
LIG_deltaCOP1_diTrp_1 661 667 PF00928 0.573
LIG_EH1_1 390 398 PF00400 0.595
LIG_FHA_1 249 255 PF00498 0.645
LIG_FHA_1 278 284 PF00498 0.638
LIG_FHA_1 424 430 PF00498 0.642
LIG_FHA_1 490 496 PF00498 0.566
LIG_FHA_1 589 595 PF00498 0.582
LIG_FHA_2 320 326 PF00498 0.600
LIG_FHA_2 365 371 PF00498 0.492
LIG_FHA_2 408 414 PF00498 0.639
LIG_FHA_2 471 477 PF00498 0.592
LIG_FHA_2 519 525 PF00498 0.549
LIG_FHA_2 600 606 PF00498 0.669
LIG_GBD_Chelix_1 577 585 PF00786 0.581
LIG_Integrin_RGD_1 168 170 PF01839 0.590
LIG_LIR_Apic_2 172 177 PF02991 0.647
LIG_LIR_Apic_2 265 271 PF02991 0.636
LIG_LIR_Gen_1 498 508 PF02991 0.569
LIG_LIR_Nem_3 498 503 PF02991 0.571
LIG_LIR_Nem_3 665 670 PF02991 0.503
LIG_MYND_1 684 688 PF01753 0.583
LIG_Pex14_1 664 668 PF04695 0.569
LIG_PTAP_UEV_1 194 199 PF05743 0.688
LIG_SH2_CRK 460 464 PF00017 0.619
LIG_SH2_NCK_1 286 290 PF00017 0.647
LIG_SH2_STAT5 234 237 PF00017 0.734
LIG_SH2_STAT5 286 289 PF00017 0.649
LIG_SH2_STAT5 668 671 PF00017 0.563
LIG_SH3_3 143 149 PF00018 0.654
LIG_SH3_3 192 198 PF00018 0.711
LIG_SH3_3 216 222 PF00018 0.667
LIG_SH3_3 336 342 PF00018 0.613
LIG_SH3_3 405 411 PF00018 0.587
LIG_SH3_3 415 421 PF00018 0.623
LIG_SH3_3 422 428 PF00018 0.547
LIG_SH3_3 502 508 PF00018 0.624
LIG_SH3_3 685 691 PF00018 0.661
LIG_SUMO_SIM_par_1 612 617 PF11976 0.451
LIG_SUMO_SIM_par_1 631 638 PF11976 0.564
LIG_TRAF2_1 367 370 PF00917 0.560
LIG_TRAF2_1 392 395 PF00917 0.564
LIG_WW_3 9 13 PF00397 0.664
MOD_CDC14_SPxK_1 272 275 PF00782 0.635
MOD_CDK_SPK_2 232 237 PF00069 0.682
MOD_CDK_SPK_2 269 274 PF00069 0.556
MOD_CDK_SPxK_1 232 238 PF00069 0.657
MOD_CDK_SPxK_1 269 275 PF00069 0.641
MOD_CDK_SPxxK_3 152 159 PF00069 0.669
MOD_CK1_1 152 158 PF00069 0.708
MOD_CK1_1 190 196 PF00069 0.665
MOD_CK1_1 278 284 PF00069 0.626
MOD_CK1_1 3 9 PF00069 0.613
MOD_CK1_1 442 448 PF00069 0.658
MOD_CK1_1 51 57 PF00069 0.640
MOD_CK1_1 561 567 PF00069 0.596
MOD_CK1_1 588 594 PF00069 0.601
MOD_CK1_1 595 601 PF00069 0.612
MOD_CK1_1 95 101 PF00069 0.716
MOD_CK2_1 364 370 PF00069 0.493
MOD_CK2_1 407 413 PF00069 0.637
MOD_CK2_1 470 476 PF00069 0.587
MOD_CK2_1 518 524 PF00069 0.573
MOD_CK2_1 599 605 PF00069 0.678
MOD_CMANNOS 664 667 PF00535 0.571
MOD_GlcNHglycan 12 15 PF01048 0.692
MOD_GlcNHglycan 151 154 PF01048 0.583
MOD_GlcNHglycan 195 198 PF01048 0.614
MOD_GlcNHglycan 2 5 PF01048 0.672
MOD_GlcNHglycan 25 28 PF01048 0.588
MOD_GlcNHglycan 294 297 PF01048 0.696
MOD_GlcNHglycan 301 304 PF01048 0.633
MOD_GlcNHglycan 308 311 PF01048 0.573
MOD_GlcNHglycan 322 325 PF01048 0.566
MOD_GlcNHglycan 34 37 PF01048 0.657
MOD_GlcNHglycan 345 348 PF01048 0.626
MOD_GlcNHglycan 349 352 PF01048 0.630
MOD_GlcNHglycan 41 44 PF01048 0.545
MOD_GlcNHglycan 445 448 PF01048 0.605
MOD_GlcNHglycan 516 519 PF01048 0.638
MOD_GlcNHglycan 528 531 PF01048 0.557
MOD_GlcNHglycan 53 56 PF01048 0.619
MOD_GlcNHglycan 58 61 PF01048 0.566
MOD_GlcNHglycan 587 590 PF01048 0.572
MOD_GlcNHglycan 594 597 PF01048 0.567
MOD_GlcNHglycan 66 69 PF01048 0.591
MOD_GlcNHglycan 692 695 PF01048 0.600
MOD_GlcNHglycan 699 703 PF01048 0.568
MOD_GSK3_1 193 200 PF00069 0.735
MOD_GSK3_1 224 231 PF00069 0.551
MOD_GSK3_1 258 265 PF00069 0.576
MOD_GSK3_1 275 282 PF00069 0.540
MOD_GSK3_1 343 350 PF00069 0.623
MOD_GSK3_1 438 445 PF00069 0.649
MOD_GSK3_1 514 521 PF00069 0.522
MOD_GSK3_1 526 533 PF00069 0.549
MOD_GSK3_1 56 63 PF00069 0.682
MOD_GSK3_1 584 591 PF00069 0.614
MOD_GSK3_1 592 599 PF00069 0.633
MOD_GSK3_1 700 707 PF00069 0.658
MOD_LATS_1 74 80 PF00433 0.736
MOD_N-GLC_1 501 506 PF02516 0.499
MOD_N-GLC_1 76 81 PF02516 0.681
MOD_NEK2_1 306 311 PF00069 0.561
MOD_NEK2_1 558 563 PF00069 0.640
MOD_NEK2_1 585 590 PF00069 0.616
MOD_NEK2_1 92 97 PF00069 0.716
MOD_NEK2_2 48 53 PF00069 0.686
MOD_NEK2_2 552 557 PF00069 0.501
MOD_PIKK_1 131 137 PF00454 0.735
MOD_PIKK_1 222 228 PF00454 0.678
MOD_PIKK_1 255 261 PF00454 0.664
MOD_PIKK_1 468 474 PF00454 0.657
MOD_PK_1 12 18 PF00069 0.611
MOD_PKA_2 149 155 PF00069 0.654
MOD_PKA_2 222 228 PF00069 0.678
MOD_PKA_2 385 391 PF00069 0.655
MOD_PKA_2 439 445 PF00069 0.581
MOD_PKA_2 546 552 PF00069 0.571
MOD_PKA_2 559 565 PF00069 0.484
MOD_Plk_1 501 507 PF00069 0.499
MOD_Plk_4 263 269 PF00069 0.580
MOD_Plk_4 414 420 PF00069 0.536
MOD_Plk_4 459 465 PF00069 0.620
MOD_Plk_4 552 558 PF00069 0.592
MOD_ProDKin_1 152 158 PF00069 0.736
MOD_ProDKin_1 173 179 PF00069 0.602
MOD_ProDKin_1 190 196 PF00069 0.617
MOD_ProDKin_1 232 238 PF00069 0.710
MOD_ProDKin_1 269 275 PF00069 0.665
MOD_ProDKin_1 284 290 PF00069 0.654
MOD_ProDKin_1 407 413 PF00069 0.673
MOD_SUMO_rev_2 523 528 PF00179 0.567
TRG_ENDOCYTIC_2 460 463 PF00928 0.621
TRG_ER_diArg_1 136 139 PF00400 0.734
TRG_ER_diArg_1 236 238 PF00400 0.656
TRG_ER_diArg_1 273 275 PF00400 0.555
TRG_ER_diArg_1 329 332 PF00400 0.629
TRG_ER_diArg_1 373 376 PF00400 0.627
TRG_ER_diArg_1 511 513 PF00400 0.571
TRG_ER_diArg_1 622 624 PF00400 0.545
TRG_ER_diArg_1 652 654 PF00400 0.581
TRG_NLS_MonoCore_2 327 332 PF00514 0.662
TRG_NLS_MonoExtC_3 327 332 PF00514 0.662
TRG_NLS_MonoExtN_4 328 334 PF00514 0.658
TRG_Pf-PMV_PEXEL_1 433 437 PF00026 0.647
TRG_Pf-PMV_PEXEL_1 493 498 PF00026 0.585

Homologs

Protein Taxonomy Sequence identity Coverage
A4H819 Leishmania braziliensis 54% 99%
A4HWE7 Leishmania infantum 97% 100%
E9AQ47 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 99%
Q4QFD6 Leishmania major 89% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS