LeishMANIAdb
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60S_ribosomal_protein_L37a/GeneDB:LmjF.36.1925

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
60S_ribosomal_protein_L37a/GeneDB:LmjF.36.1925
Gene product:
60S ribosomal protein L37a, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IC65_LEIDO
TriTrypDb:
LdBPK_212190.1 , LdCL_210027600 , LdCL_360025700 , LDHU3_21.2600 , LDHU3_36.2630
Length:
92

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S ribosomal L37a

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 30
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. yes yes: 35
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 35
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005730 nucleolus 5 1
GO:0005840 ribosome 5 11
GO:0043226 organelle 2 11
GO:0043228 non-membrane-bounded organelle 3 11
GO:0043229 intracellular organelle 3 11
GO:0043232 intracellular non-membrane-bounded organelle 4 11
GO:0110165 cellular anatomical entity 1 11
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Expansion

Sequence features

A0A3Q8IC65
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IC65

PDB structure(s): 6az3_o

Function

Biological processes
TermNameLevelCount
GO:0006412 translation 4 11
GO:0006518 peptide metabolic process 4 11
GO:0006807 nitrogen compound metabolic process 2 11
GO:0008152 metabolic process 1 11
GO:0009058 biosynthetic process 2 11
GO:0009059 macromolecule biosynthetic process 4 11
GO:0009987 cellular process 1 11
GO:0019538 protein metabolic process 3 11
GO:0034641 cellular nitrogen compound metabolic process 3 11
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 11
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Molecular functions
TermNameLevelCount
GO:0003735 structural constituent of ribosome 2 11
GO:0005198 structural molecule activity 1 11
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 22 24 PF00675 0.368
CLV_NRD_NRD_1 48 50 PF00675 0.368
CLV_NRD_NRD_1 84 86 PF00675 0.377
CLV_PCSK_KEX2_1 24 26 PF00082 0.368
CLV_PCSK_KEX2_1 3 5 PF00082 0.368
CLV_PCSK_KEX2_1 48 50 PF00082 0.368
CLV_PCSK_KEX2_1 84 86 PF00082 0.368
CLV_PCSK_PC1ET2_1 24 26 PF00082 0.368
CLV_PCSK_PC1ET2_1 3 5 PF00082 0.368
CLV_PCSK_PC7_1 80 86 PF00082 0.368
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HYR6 Leptomonas seymouri 98% 100%
A0A0S4IY08 Bodo saltans 92% 100%
A0A1D8PP14 Candida albicans (strain SC5314 / ATCC MYA-2876) 63% 100%
A1RSS8 Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) 39% 91%
A4FZT8 Methanococcus maripaludis (strain C5 / ATCC BAA-1333) 37% 96%
A4HLC4 Leishmania braziliensis 100% 100%
A4HP58 Leishmania braziliensis 100% 100%
A4HZI8 Leishmania infantum 100% 100%
A4S6Z4 Ostreococcus lucimarinus (strain CCE9901) 68% 100%
A5UNQ7 Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS) 36% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS