60S_ribosomal_protein_L37a/GeneDB:LmjF.36.1925

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L37a, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IC65_LEIDO

TriTrypDb:

LdBPK_212190.1 , LdCL_210027600 , LdCL_360025700 , LDHU3_21.2600 , LDHU3_36.2630

Length:

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S ribosomal L37a

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 35

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 35

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0005840	ribosome	5	11
GO:0043226	organelle	2	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

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Expansion

Sequence features

A0A3Q8IC65

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IC65

PDB structure(s): 6az3_o

Function

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Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	11
GO:0006518	peptide metabolic process	4	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009058	biosynthetic process	2	11
GO:0009059	macromolecule biosynthetic process	4	11
GO:0009987	cellular process	1	11
GO:0019538	protein metabolic process	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	11

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Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	11
GO:0005198	structural molecule activity	1	11

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	22	24	PF00675	0.368
CLV_NRD_NRD_1	48	50	PF00675	0.368
CLV_NRD_NRD_1	84	86	PF00675	0.377
CLV_PCSK_KEX2_1	24	26	PF00082	0.368
CLV_PCSK_KEX2_1	3	5	PF00082	0.368
CLV_PCSK_KEX2_1	48	50	PF00082	0.368
CLV_PCSK_KEX2_1	84	86	PF00082	0.368
CLV_PCSK_PC1ET2_1	24	26	PF00082	0.368
CLV_PCSK_PC1ET2_1	3	5	PF00082	0.368
CLV_PCSK_PC7_1	80	86	PF00082	0.368

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYR6	Leptomonas seymouri	98%	100%
A0A0S4IY08	Bodo saltans	92%	100%
A0A1D8PP14	Candida albicans (strain SC5314 / ATCC MYA-2876)	63%	100%
A1RSS8	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	39%	91%
A4FZT8	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	37%	96%
A4HLC4	Leishmania braziliensis	100%	100%
A4HP58	Leishmania braziliensis	100%	100%
A4HZI8	Leishmania infantum	100%	100%
A4S6Z4	Ostreococcus lucimarinus (strain CCE9901)	68%	100%
A5UNQ7	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	36%	100%

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