LeishMANIAdb
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DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA helicase
Gene product:
ATP-dependent DEAD/H DNA helicase recQ, putative
Species:
Leishmania donovani
UniProt:
A0A3Q8IC54_LEIDO
TriTrypDb:
LdBPK_241590.1 * , LdCL_240021100 , LDHU3_24.1940
Length:
1675

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005694 chromosome 5 1
GO:0005737 cytoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3Q8IC54
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 7
GO:0006259 DNA metabolic process 4 7
GO:0006310 DNA recombination 5 7
GO:0006725 cellular aromatic compound metabolic process 3 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0008152 metabolic process 1 7
GO:0009987 cellular process 1 7
GO:0034641 cellular nitrogen compound metabolic process 3 7
GO:0043170 macromolecule metabolic process 3 7
GO:0044237 cellular metabolic process 2 7
GO:0044238 primary metabolic process 2 7
GO:0044260 obsolete cellular macromolecule metabolic process 3 7
GO:0046483 heterocycle metabolic process 3 7
GO:0071704 organic substance metabolic process 2 7
GO:0090304 nucleic acid metabolic process 4 7
GO:1901360 organic cyclic compound metabolic process 3 7
GO:0000724 double-strand break repair via homologous recombination 7 1
GO:0000725 recombinational repair 6 1
GO:0006268 DNA unwinding involved in DNA replication 9 1
GO:0006281 DNA repair 5 1
GO:0006302 double-strand break repair 6 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0006996 organelle organization 4 1
GO:0016043 cellular component organization 3 1
GO:0032392 DNA geometric change 7 1
GO:0032508 DNA duplex unwinding 8 1
GO:0033554 cellular response to stress 3 1
GO:0050896 response to stimulus 1 1
GO:0051276 chromosome organization 5 1
GO:0051716 cellular response to stimulus 2 1
GO:0071103 DNA conformation change 6 1
GO:0071840 cellular component organization or biogenesis 2 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 7
GO:0003676 nucleic acid binding 3 7
GO:0003824 catalytic activity 1 7
GO:0004386 helicase activity 2 7
GO:0005488 binding 1 7
GO:0005524 ATP binding 5 7
GO:0016787 hydrolase activity 2 7
GO:0017076 purine nucleotide binding 4 7
GO:0030554 adenyl nucleotide binding 5 7
GO:0032553 ribonucleotide binding 3 7
GO:0032555 purine ribonucleotide binding 4 7
GO:0032559 adenyl ribonucleotide binding 5 7
GO:0035639 purine ribonucleoside triphosphate binding 4 7
GO:0036094 small molecule binding 2 7
GO:0043167 ion binding 2 7
GO:0043168 anion binding 3 7
GO:0097159 organic cyclic compound binding 2 7
GO:0097367 carbohydrate derivative binding 2 7
GO:0140640 catalytic activity, acting on a nucleic acid 2 7
GO:0140657 ATP-dependent activity 1 7
GO:1901265 nucleoside phosphate binding 3 7
GO:1901363 heterocyclic compound binding 2 7
GO:0003678 DNA helicase activity 3 1
GO:0008094 ATP-dependent activity, acting on DNA 2 1
GO:0009378 four-way junction helicase activity 4 1
GO:0043138 3'-5' DNA helicase activity 4 1
GO:0140097 catalytic activity, acting on DNA 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 169 173 PF00656 0.462
CLV_C14_Caspase3-7 758 762 PF00656 0.333
CLV_C14_Caspase3-7 806 810 PF00656 0.480
CLV_C14_Caspase3-7 877 881 PF00656 0.612
CLV_C14_Caspase3-7 976 980 PF00656 0.664
CLV_MEL_PAP_1 469 475 PF00089 0.389
CLV_NRD_NRD_1 1223 1225 PF00675 0.522
CLV_NRD_NRD_1 190 192 PF00675 0.496
CLV_NRD_NRD_1 2 4 PF00675 0.440
CLV_NRD_NRD_1 241 243 PF00675 0.369
CLV_NRD_NRD_1 333 335 PF00675 0.269
CLV_NRD_NRD_1 398 400 PF00675 0.269
CLV_NRD_NRD_1 485 487 PF00675 0.277
CLV_NRD_NRD_1 498 500 PF00675 0.272
CLV_NRD_NRD_1 618 620 PF00675 0.269
CLV_NRD_NRD_1 860 862 PF00675 0.654
CLV_NRD_NRD_1 869 871 PF00675 0.514
CLV_NRD_NRD_1 940 942 PF00675 0.589
CLV_NRD_NRD_1 972 974 PF00675 0.629
CLV_PCSK_FUR_1 1221 1225 PF00082 0.579
CLV_PCSK_KEX2_1 1077 1079 PF00082 0.269
CLV_PCSK_KEX2_1 1223 1225 PF00082 0.522
CLV_PCSK_KEX2_1 2 4 PF00082 0.440
CLV_PCSK_KEX2_1 241 243 PF00082 0.369
CLV_PCSK_KEX2_1 333 335 PF00082 0.269
CLV_PCSK_KEX2_1 405 407 PF00082 0.316
CLV_PCSK_KEX2_1 498 500 PF00082 0.269
CLV_PCSK_KEX2_1 617 619 PF00082 0.269
CLV_PCSK_KEX2_1 838 840 PF00082 0.426
CLV_PCSK_KEX2_1 860 862 PF00082 0.653
CLV_PCSK_KEX2_1 869 871 PF00082 0.512
CLV_PCSK_KEX2_1 940 942 PF00082 0.589
CLV_PCSK_KEX2_1 974 976 PF00082 0.620
CLV_PCSK_PC1ET2_1 1077 1079 PF00082 0.269
CLV_PCSK_PC1ET2_1 405 407 PF00082 0.316
CLV_PCSK_PC1ET2_1 838 840 PF00082 0.382
CLV_PCSK_PC1ET2_1 860 862 PF00082 0.665
CLV_PCSK_PC1ET2_1 974 976 PF00082 0.620
CLV_PCSK_SKI1_1 1015 1019 PF00082 0.436
CLV_PCSK_SKI1_1 1110 1114 PF00082 0.486
CLV_PCSK_SKI1_1 1179 1183 PF00082 0.627
CLV_PCSK_SKI1_1 1224 1228 PF00082 0.549
CLV_PCSK_SKI1_1 1629 1633 PF00082 0.545
CLV_PCSK_SKI1_1 210 214 PF00082 0.493
CLV_PCSK_SKI1_1 245 249 PF00082 0.340
CLV_PCSK_SKI1_1 268 272 PF00082 0.269
CLV_PCSK_SKI1_1 3 7 PF00082 0.447
CLV_PCSK_SKI1_1 334 338 PF00082 0.269
CLV_PCSK_SKI1_1 373 377 PF00082 0.269
CLV_PCSK_SKI1_1 499 503 PF00082 0.274
CLV_PCSK_SKI1_1 740 744 PF00082 0.395
CLV_PCSK_SKI1_1 745 749 PF00082 0.360
CLV_PCSK_SKI1_1 785 789 PF00082 0.445
CLV_PCSK_SKI1_1 792 796 PF00082 0.437
CLV_PCSK_SKI1_1 799 803 PF00082 0.466
CLV_PCSK_SKI1_1 873 877 PF00082 0.618
DEG_APCC_DBOX_1 14 22 PF00400 0.530
DEG_APCC_DBOX_1 521 529 PF00400 0.469
DEG_APCC_DBOX_1 596 604 PF00400 0.469
DEG_APCC_DBOX_1 744 752 PF00400 0.394
DEG_Nend_UBRbox_1 1 4 PF02207 0.441
DEG_SCF_FBW7_1 1508 1514 PF00400 0.520
DEG_SCF_FBW7_1 60 65 PF00400 0.539
DEG_SCF_FBW7_1 649 656 PF00400 0.430
DEG_SPOP_SBC_1 1350 1354 PF00917 0.494
DOC_CKS1_1 1185 1190 PF01111 0.492
DOC_CKS1_1 1338 1343 PF01111 0.567
DOC_CKS1_1 1508 1513 PF01111 0.516
DOC_CKS1_1 1549 1554 PF01111 0.513
DOC_CKS1_1 351 356 PF01111 0.469
DOC_CKS1_1 409 414 PF01111 0.469
DOC_CKS1_1 650 655 PF01111 0.430
DOC_CKS1_1 914 919 PF01111 0.540
DOC_CKS1_1 923 928 PF01111 0.576
DOC_CYCLIN_RxL_1 1010 1021 PF00134 0.437
DOC_CYCLIN_RxL_1 331 339 PF00134 0.469
DOC_CYCLIN_RxL_1 427 436 PF00134 0.349
DOC_CYCLIN_RxL_1 737 746 PF00134 0.398
DOC_CYCLIN_yCln2_LP_2 1182 1188 PF00134 0.556
DOC_MAPK_gen_1 1085 1095 PF00069 0.537
DOC_MAPK_gen_1 457 464 PF00069 0.413
DOC_MAPK_gen_1 519 527 PF00069 0.469
DOC_MAPK_MEF2A_6 1247 1255 PF00069 0.595
DOC_MAPK_MEF2A_6 215 223 PF00069 0.483
DOC_MAPK_MEF2A_6 825 833 PF00069 0.452
DOC_PP2B_LxvP_1 1054 1057 PF13499 0.469
DOC_PP2B_LxvP_1 1267 1270 PF13499 0.581
DOC_PP2B_LxvP_1 1359 1362 PF13499 0.603
DOC_PP2B_LxvP_1 1413 1416 PF13499 0.583
DOC_PP2B_LxvP_1 163 166 PF13499 0.465
DOC_PP4_FxxP_1 1327 1330 PF00568 0.583
DOC_PP4_FxxP_1 1332 1335 PF00568 0.531
DOC_SPAK_OSR1_1 378 382 PF12202 0.469
DOC_USP7_MATH_1 1001 1005 PF00917 0.439
DOC_USP7_MATH_1 1125 1129 PF00917 0.538
DOC_USP7_MATH_1 1152 1156 PF00917 0.404
DOC_USP7_MATH_1 1191 1195 PF00917 0.619
DOC_USP7_MATH_1 1345 1349 PF00917 0.630
DOC_USP7_MATH_1 1351 1355 PF00917 0.541
DOC_USP7_MATH_1 1362 1366 PF00917 0.511
DOC_USP7_MATH_1 1414 1418 PF00917 0.634
DOC_USP7_MATH_1 1443 1447 PF00917 0.563
DOC_USP7_MATH_1 1511 1515 PF00917 0.571
DOC_USP7_MATH_1 1557 1561 PF00917 0.632
DOC_USP7_MATH_1 1568 1572 PF00917 0.708
DOC_USP7_MATH_1 1608 1612 PF00917 0.570
DOC_USP7_MATH_1 1620 1624 PF00917 0.474
DOC_USP7_MATH_1 166 170 PF00917 0.635
DOC_USP7_MATH_1 173 177 PF00917 0.480
DOC_USP7_MATH_1 183 187 PF00917 0.537
DOC_USP7_MATH_1 332 336 PF00917 0.469
DOC_USP7_MATH_1 653 657 PF00917 0.507
DOC_USP7_MATH_1 736 740 PF00917 0.465
DOC_USP7_MATH_1 803 807 PF00917 0.430
DOC_USP7_MATH_1 814 818 PF00917 0.506
DOC_USP7_MATH_1 879 883 PF00917 0.605
DOC_USP7_MATH_1 889 893 PF00917 0.557
DOC_USP7_MATH_1 915 919 PF00917 0.515
DOC_USP7_MATH_1 931 935 PF00917 0.510
DOC_USP7_MATH_2 729 735 PF00917 0.432
DOC_USP7_UBL2_3 1073 1077 PF12436 0.469
DOC_USP7_UBL2_3 733 737 PF12436 0.508
DOC_USP7_UBL2_3 862 866 PF12436 0.641
DOC_WW_Pin1_4 115 120 PF00397 0.627
DOC_WW_Pin1_4 1184 1189 PF00397 0.520
DOC_WW_Pin1_4 1198 1203 PF00397 0.568
DOC_WW_Pin1_4 1247 1252 PF00397 0.590
DOC_WW_Pin1_4 1337 1342 PF00397 0.557
DOC_WW_Pin1_4 1352 1357 PF00397 0.490
DOC_WW_Pin1_4 1372 1377 PF00397 0.553
DOC_WW_Pin1_4 1450 1455 PF00397 0.579
DOC_WW_Pin1_4 1507 1512 PF00397 0.503
DOC_WW_Pin1_4 1548 1553 PF00397 0.523
DOC_WW_Pin1_4 1633 1638 PF00397 0.565
DOC_WW_Pin1_4 298 303 PF00397 0.469
DOC_WW_Pin1_4 350 355 PF00397 0.469
DOC_WW_Pin1_4 408 413 PF00397 0.469
DOC_WW_Pin1_4 471 476 PF00397 0.383
DOC_WW_Pin1_4 58 63 PF00397 0.540
DOC_WW_Pin1_4 649 654 PF00397 0.430
DOC_WW_Pin1_4 725 730 PF00397 0.635
DOC_WW_Pin1_4 76 81 PF00397 0.541
DOC_WW_Pin1_4 774 779 PF00397 0.451
DOC_WW_Pin1_4 913 918 PF00397 0.531
DOC_WW_Pin1_4 922 927 PF00397 0.572
LIG_14-3-3_CanoR_1 1024 1030 PF00244 0.521
LIG_14-3-3_CanoR_1 1049 1057 PF00244 0.472
LIG_14-3-3_CanoR_1 1124 1134 PF00244 0.555
LIG_14-3-3_CanoR_1 1148 1157 PF00244 0.524
LIG_14-3-3_CanoR_1 1192 1202 PF00244 0.574
LIG_14-3-3_CanoR_1 1221 1227 PF00244 0.528
LIG_14-3-3_CanoR_1 1247 1251 PF00244 0.525
LIG_14-3-3_CanoR_1 1252 1256 PF00244 0.503
LIG_14-3-3_CanoR_1 1465 1469 PF00244 0.558
LIG_14-3-3_CanoR_1 1570 1574 PF00244 0.628
LIG_14-3-3_CanoR_1 191 197 PF00244 0.521
LIG_14-3-3_CanoR_1 233 243 PF00244 0.409
LIG_14-3-3_CanoR_1 333 337 PF00244 0.469
LIG_14-3-3_CanoR_1 399 404 PF00244 0.469
LIG_14-3-3_CanoR_1 597 607 PF00244 0.469
LIG_14-3-3_CanoR_1 709 719 PF00244 0.424
LIG_14-3-3_CanoR_1 792 797 PF00244 0.495
LIG_14-3-3_CanoR_1 850 856 PF00244 0.604
LIG_Actin_WH2_2 421 437 PF00022 0.495
LIG_Actin_WH2_2 679 697 PF00022 0.318
LIG_APCC_ABBA_1 1329 1334 PF00400 0.539
LIG_APCC_ABBA_1 753 758 PF00400 0.333
LIG_APCC_ABBAyCdc20_2 333 339 PF00400 0.469
LIG_BIR_III_4 172 176 PF00653 0.461
LIG_BRCT_BRCA1_1 1377 1381 PF00533 0.458
LIG_BRCT_BRCA1_1 1622 1626 PF00533 0.541
LIG_BRCT_BRCA1_1 359 363 PF00533 0.469
LIG_Clathr_ClatBox_1 1065 1069 PF01394 0.516
LIG_Clathr_ClatBox_1 18 22 PF01394 0.551
LIG_CSL_BTD_1 1508 1511 PF09270 0.562
LIG_CtBP_PxDLS_1 66 70 PF00389 0.546
LIG_EH1_1 343 351 PF00400 0.516
LIG_eIF4E_1 284 290 PF01652 0.469
LIG_EVH1_1 1332 1336 PF00568 0.528
LIG_EVH1_1 649 653 PF00568 0.430
LIG_FHA_1 1049 1055 PF00498 0.469
LIG_FHA_1 1298 1304 PF00498 0.548
LIG_FHA_1 1410 1416 PF00498 0.541
LIG_FHA_1 214 220 PF00498 0.483
LIG_FHA_1 27 33 PF00498 0.457
LIG_FHA_1 295 301 PF00498 0.469
LIG_FHA_1 419 425 PF00498 0.469
LIG_FHA_1 429 435 PF00498 0.325
LIG_FHA_1 793 799 PF00498 0.496
LIG_FHA_2 1213 1219 PF00498 0.602
LIG_FHA_2 1587 1593 PF00498 0.489
LIG_FHA_2 1667 1673 PF00498 0.606
LIG_FHA_2 417 423 PF00498 0.469
LIG_FHA_2 519 525 PF00498 0.469
LIG_FHA_2 577 583 PF00498 0.502
LIG_FHA_2 674 680 PF00498 0.418
LIG_FHA_2 726 732 PF00498 0.545
LIG_FHA_2 744 750 PF00498 0.259
LIG_FHA_2 821 827 PF00498 0.453
LIG_FHA_2 881 887 PF00498 0.604
LIG_FHA_2 955 961 PF00498 0.653
LIG_FHA_2 974 980 PF00498 0.670
LIG_Integrin_isoDGR_2 1169 1171 PF01839 0.444
LIG_Integrin_RGD_1 155 157 PF01839 0.452
LIG_Integrin_RGD_1 977 979 PF01839 0.664
LIG_LIR_Apic_2 281 287 PF02991 0.469
LIG_LIR_Apic_2 348 354 PF02991 0.469
LIG_LIR_Gen_1 1038 1047 PF02991 0.469
LIG_LIR_Gen_1 1282 1291 PF02991 0.543
LIG_LIR_Gen_1 252 263 PF02991 0.455
LIG_LIR_Gen_1 269 275 PF02991 0.401
LIG_LIR_Gen_1 309 320 PF02991 0.469
LIG_LIR_Gen_1 43 54 PF02991 0.426
LIG_LIR_Gen_1 688 696 PF02991 0.381
LIG_LIR_Nem_3 1282 1287 PF02991 0.533
LIG_LIR_Nem_3 195 199 PF02991 0.473
LIG_LIR_Nem_3 252 258 PF02991 0.477
LIG_LIR_Nem_3 269 274 PF02991 0.401
LIG_LIR_Nem_3 309 315 PF02991 0.469
LIG_LIR_Nem_3 397 401 PF02991 0.469
LIG_LIR_Nem_3 43 49 PF02991 0.409
LIG_LIR_Nem_3 688 693 PF02991 0.438
LIG_LIR_Nem_3 809 815 PF02991 0.522
LIG_MYND_1 1265 1269 PF01753 0.654
LIG_MYND_1 1358 1362 PF01753 0.604
LIG_MYND_1 287 291 PF01753 0.469
LIG_MYND_1 647 651 PF01753 0.516
LIG_NRBOX 1013 1019 PF00104 0.440
LIG_PCNA_yPIPBox_3 1013 1026 PF02747 0.429
LIG_Pex14_1 390 394 PF04695 0.469
LIG_Pex14_2 440 444 PF04695 0.321
LIG_Rb_pABgroove_1 828 836 PF01858 0.434
LIG_SH2_CRK 1284 1288 PF00017 0.534
LIG_SH2_CRK 284 288 PF00017 0.469
LIG_SH2_CRK 312 316 PF00017 0.469
LIG_SH2_CRK 398 402 PF00017 0.469
LIG_SH2_CRK 690 694 PF00017 0.382
LIG_SH2_NCK_1 312 316 PF00017 0.469
LIG_SH2_NCK_1 93 97 PF00017 0.448
LIG_SH2_PTP2 1092 1095 PF00017 0.420
LIG_SH2_PTP2 351 354 PF00017 0.469
LIG_SH2_SRC 1092 1095 PF00017 0.355
LIG_SH2_SRC 559 562 PF00017 0.543
LIG_SH2_SRC 690 693 PF00017 0.382
LIG_SH2_STAP1 199 203 PF00017 0.463
LIG_SH2_STAP1 312 316 PF00017 0.469
LIG_SH2_STAP1 690 694 PF00017 0.425
LIG_SH2_STAT3 199 202 PF00017 0.465
LIG_SH2_STAT3 451 454 PF00017 0.436
LIG_SH2_STAT5 101 104 PF00017 0.521
LIG_SH2_STAT5 1092 1095 PF00017 0.355
LIG_SH2_STAT5 1468 1471 PF00017 0.536
LIG_SH2_STAT5 1539 1542 PF00017 0.529
LIG_SH2_STAT5 351 354 PF00017 0.469
LIG_SH2_STAT5 356 359 PF00017 0.469
LIG_SH2_STAT5 482 485 PF00017 0.469
LIG_SH2_STAT5 545 548 PF00017 0.469
LIG_SH2_STAT5 609 612 PF00017 0.493
LIG_SH2_STAT5 874 877 PF00017 0.565
LIG_SH2_STAT5 919 922 PF00017 0.572
LIG_SH3_1 406 412 PF00018 0.477
LIG_SH3_2 1185 1190 PF14604 0.492
LIG_SH3_3 113 119 PF00018 0.584
LIG_SH3_3 1182 1188 PF00018 0.515
LIG_SH3_3 1207 1213 PF00018 0.616
LIG_SH3_3 1262 1268 PF00018 0.620
LIG_SH3_3 1311 1317 PF00018 0.675
LIG_SH3_3 1319 1325 PF00018 0.552
LIG_SH3_3 1327 1333 PF00018 0.525
LIG_SH3_3 1373 1379 PF00018 0.562
LIG_SH3_3 1505 1511 PF00018 0.598
LIG_SH3_3 1519 1525 PF00018 0.598
LIG_SH3_3 216 222 PF00018 0.483
LIG_SH3_3 269 275 PF00018 0.469
LIG_SH3_3 296 302 PF00018 0.469
LIG_SH3_3 406 412 PF00018 0.451
LIG_SH3_3 644 650 PF00018 0.472
LIG_SH3_3 74 80 PF00018 0.515
LIG_SH3_3 920 926 PF00018 0.616
LIG_SH3_3 965 971 PF00018 0.695
LIG_SH3_4 862 869 PF00018 0.604
LIG_SUMO_SIM_anti_2 1492 1500 PF11976 0.570
LIG_SUMO_SIM_anti_2 16 25 PF11976 0.514
LIG_SUMO_SIM_anti_2 656 661 PF11976 0.430
LIG_SUMO_SIM_par_1 1064 1069 PF11976 0.516
LIG_SUMO_SIM_par_1 1179 1184 PF11976 0.541
LIG_SUMO_SIM_par_1 1411 1418 PF11976 0.522
LIG_SUMO_SIM_par_1 16 25 PF11976 0.514
LIG_SUMO_SIM_par_1 296 301 PF11976 0.469
LIG_SUMO_SIM_par_1 430 436 PF11976 0.344
LIG_SUMO_SIM_par_1 829 835 PF11976 0.455
LIG_TRAF2_1 855 858 PF00917 0.567
LIG_TRAF2_1 892 895 PF00917 0.627
LIG_TRFH_1 271 275 PF08558 0.469
LIG_UBA3_1 1065 1073 PF00899 0.516
LIG_WRC_WIRS_1 1226 1231 PF05994 0.541
LIG_WRC_WIRS_1 903 908 PF05994 0.555
LIG_WW_2 1265 1268 PF00397 0.656
LIG_WW_2 647 650 PF00397 0.484
LIG_WW_3 970 974 PF00397 0.698
MOD_CDK_SPK_2 1247 1252 PF00069 0.546
MOD_CDK_SPxK_1 1184 1190 PF00069 0.518
MOD_CDK_SPxK_1 1198 1204 PF00069 0.566
MOD_CDK_SPxK_1 922 928 PF00069 0.570
MOD_CK1_1 114 120 PF00069 0.708
MOD_CK1_1 1194 1200 PF00069 0.591
MOD_CK1_1 1230 1236 PF00069 0.616
MOD_CK1_1 1246 1252 PF00069 0.437
MOD_CK1_1 1352 1358 PF00069 0.564
MOD_CK1_1 1375 1381 PF00069 0.649
MOD_CK1_1 1434 1440 PF00069 0.627
MOD_CK1_1 1569 1575 PF00069 0.687
MOD_CK1_1 1611 1617 PF00069 0.569
MOD_CK1_1 176 182 PF00069 0.512
MOD_CK1_1 186 192 PF00069 0.427
MOD_CK1_1 474 480 PF00069 0.314
MOD_CK1_1 578 584 PF00069 0.315
MOD_CK1_1 599 605 PF00069 0.469
MOD_CK1_1 658 664 PF00069 0.494
MOD_CK1_1 68 74 PF00069 0.558
MOD_CK1_1 817 823 PF00069 0.515
MOD_CK1_1 897 903 PF00069 0.548
MOD_CK1_1 913 919 PF00069 0.485
MOD_CK1_1 921 927 PF00069 0.585
MOD_CK1_1 956 962 PF00069 0.634
MOD_CK2_1 1099 1105 PF00069 0.427
MOD_CK2_1 1125 1131 PF00069 0.545
MOD_CK2_1 1479 1485 PF00069 0.682
MOD_CK2_1 1615 1621 PF00069 0.545
MOD_CK2_1 1622 1628 PF00069 0.483
MOD_CK2_1 1632 1638 PF00069 0.532
MOD_CK2_1 509 515 PF00069 0.469
MOD_CK2_1 518 524 PF00069 0.469
MOD_CK2_1 673 679 PF00069 0.424
MOD_CK2_1 708 714 PF00069 0.389
MOD_CK2_1 725 731 PF00069 0.556
MOD_CK2_1 743 749 PF00069 0.264
MOD_CK2_1 888 894 PF00069 0.614
MOD_CK2_1 954 960 PF00069 0.650
MOD_Cter_Amidation 867 870 PF01082 0.628
MOD_Cter_Amidation 938 941 PF01082 0.644
MOD_DYRK1A_RPxSP_1 1247 1251 PF00069 0.588
MOD_GlcNHglycan 1127 1130 PF01048 0.495
MOD_GlcNHglycan 1150 1153 PF01048 0.495
MOD_GlcNHglycan 1154 1157 PF01048 0.434
MOD_GlcNHglycan 1196 1199 PF01048 0.655
MOD_GlcNHglycan 1207 1210 PF01048 0.536
MOD_GlcNHglycan 125 128 PF01048 0.654
MOD_GlcNHglycan 129 132 PF01048 0.651
MOD_GlcNHglycan 1347 1350 PF01048 0.512
MOD_GlcNHglycan 1382 1385 PF01048 0.563
MOD_GlcNHglycan 1433 1436 PF01048 0.599
MOD_GlcNHglycan 1473 1476 PF01048 0.517
MOD_GlcNHglycan 1479 1482 PF01048 0.608
MOD_GlcNHglycan 1493 1496 PF01048 0.486
MOD_GlcNHglycan 1553 1556 PF01048 0.757
MOD_GlcNHglycan 1557 1560 PF01048 0.609
MOD_GlcNHglycan 1610 1613 PF01048 0.591
MOD_GlcNHglycan 1638 1641 PF01048 0.597
MOD_GlcNHglycan 181 184 PF01048 0.502
MOD_GlcNHglycan 185 188 PF01048 0.457
MOD_GlcNHglycan 236 239 PF01048 0.413
MOD_GlcNHglycan 341 344 PF01048 0.263
MOD_GlcNHglycan 561 564 PF01048 0.297
MOD_GlcNHglycan 733 736 PF01048 0.414
MOD_GlcNHglycan 816 819 PF01048 0.612
MOD_GlcNHglycan 851 854 PF01048 0.566
MOD_GlcNHglycan 894 899 PF01048 0.593
MOD_GlcNHglycan 94 97 PF01048 0.487
MOD_GSK3_1 111 118 PF00069 0.613
MOD_GSK3_1 1148 1155 PF00069 0.448
MOD_GSK3_1 1194 1201 PF00069 0.599
MOD_GSK3_1 1225 1232 PF00069 0.524
MOD_GSK3_1 123 130 PF00069 0.559
MOD_GSK3_1 1243 1250 PF00069 0.413
MOD_GSK3_1 1285 1292 PF00069 0.507
MOD_GSK3_1 1345 1352 PF00069 0.533
MOD_GSK3_1 1375 1382 PF00069 0.503
MOD_GSK3_1 1405 1412 PF00069 0.566
MOD_GSK3_1 1423 1430 PF00069 0.592
MOD_GSK3_1 1450 1457 PF00069 0.575
MOD_GSK3_1 1471 1478 PF00069 0.476
MOD_GSK3_1 1479 1486 PF00069 0.628
MOD_GSK3_1 1507 1514 PF00069 0.575
MOD_GSK3_1 1551 1558 PF00069 0.594
MOD_GSK3_1 1581 1588 PF00069 0.607
MOD_GSK3_1 1610 1617 PF00069 0.545
MOD_GSK3_1 1620 1627 PF00069 0.501
MOD_GSK3_1 1632 1639 PF00069 0.538
MOD_GSK3_1 175 182 PF00069 0.522
MOD_GSK3_1 294 301 PF00069 0.469
MOD_GSK3_1 414 421 PF00069 0.503
MOD_GSK3_1 501 508 PF00069 0.469
MOD_GSK3_1 58 65 PF00069 0.550
MOD_GSK3_1 649 656 PF00069 0.465
MOD_GSK3_1 67 74 PF00069 0.577
MOD_GSK3_1 76 83 PF00069 0.500
MOD_GSK3_1 909 916 PF00069 0.712
MOD_GSK3_1 918 925 PF00069 0.588
MOD_GSK3_1 943 950 PF00069 0.553
MOD_N-GLC_1 1125 1130 PF02516 0.542
MOD_N-GLC_1 1363 1368 PF02516 0.570
MOD_N-GLC_1 173 178 PF02516 0.418
MOD_N-GLC_2 262 264 PF02516 0.269
MOD_NEK2_1 1025 1030 PF00069 0.469
MOD_NEK2_1 1050 1055 PF00069 0.469
MOD_NEK2_1 111 116 PF00069 0.640
MOD_NEK2_1 1227 1232 PF00069 0.514
MOD_NEK2_1 1388 1393 PF00069 0.510
MOD_NEK2_1 1427 1432 PF00069 0.587
MOD_NEK2_1 1449 1454 PF00069 0.574
MOD_NEK2_1 1464 1469 PF00069 0.506
MOD_NEK2_1 1479 1484 PF00069 0.522
MOD_NEK2_1 1615 1620 PF00069 0.605
MOD_NEK2_1 1631 1636 PF00069 0.529
MOD_NEK2_1 213 218 PF00069 0.482
MOD_NEK2_1 322 327 PF00069 0.469
MOD_NEK2_1 363 368 PF00069 0.469
MOD_NEK2_1 416 421 PF00069 0.474
MOD_NEK2_1 440 445 PF00069 0.357
MOD_NEK2_1 449 454 PF00069 0.391
MOD_NEK2_1 52 57 PF00069 0.459
MOD_NEK2_1 576 581 PF00069 0.530
MOD_NEK2_1 607 612 PF00069 0.474
MOD_NEK2_1 633 638 PF00069 0.493
MOD_NEK2_1 72 77 PF00069 0.485
MOD_NEK2_1 743 748 PF00069 0.485
MOD_NEK2_1 899 904 PF00069 0.598
MOD_NEK2_1 992 997 PF00069 0.424
MOD_NEK2_2 332 337 PF00069 0.469
MOD_PIKK_1 1028 1034 PF00454 0.526
MOD_PIKK_1 1454 1460 PF00454 0.556
MOD_PIKK_1 1502 1508 PF00454 0.548
MOD_PIKK_1 385 391 PF00454 0.469
MOD_PIKK_1 633 639 PF00454 0.469
MOD_PIKK_1 658 664 PF00454 0.469
MOD_PIKK_1 947 953 PF00454 0.638
MOD_PK_1 399 405 PF00069 0.469
MOD_PK_1 759 765 PF00069 0.328
MOD_PKA_1 399 405 PF00069 0.469
MOD_PKA_1 973 979 PF00069 0.612
MOD_PKA_2 1048 1054 PF00069 0.469
MOD_PKA_2 1170 1176 PF00069 0.503
MOD_PKA_2 1191 1197 PF00069 0.632
MOD_PKA_2 1222 1228 PF00069 0.523
MOD_PKA_2 1246 1252 PF00069 0.548
MOD_PKA_2 1431 1437 PF00069 0.617
MOD_PKA_2 1464 1470 PF00069 0.571
MOD_PKA_2 1555 1561 PF00069 0.662
MOD_PKA_2 1569 1575 PF00069 0.557
MOD_PKA_2 332 338 PF00069 0.469
MOD_PKA_2 518 524 PF00069 0.469
MOD_PKA_2 596 602 PF00069 0.469
MOD_PKA_2 708 714 PF00069 0.406
MOD_PKA_2 803 809 PF00069 0.409
MOD_PKA_2 846 852 PF00069 0.575
MOD_PKA_2 942 948 PF00069 0.680
MOD_PKB_1 941 949 PF00069 0.572
MOD_Plk_1 149 155 PF00069 0.527
MOD_Plk_1 1620 1626 PF00069 0.520
MOD_Plk_1 743 749 PF00069 0.481
MOD_Plk_1 808 814 PF00069 0.439
MOD_Plk_1 894 900 PF00069 0.545
MOD_Plk_1 909 915 PF00069 0.473
MOD_Plk_2-3 1099 1105 PF00069 0.427
MOD_Plk_2-3 1622 1628 PF00069 0.528
MOD_Plk_2-3 1666 1672 PF00069 0.608
MOD_Plk_2-3 673 679 PF00069 0.424
MOD_Plk_2-3 880 886 PF00069 0.542
MOD_Plk_4 1025 1031 PF00069 0.469
MOD_Plk_4 1043 1049 PF00069 0.469
MOD_Plk_4 1406 1412 PF00069 0.535
MOD_Plk_4 1464 1470 PF00069 0.503
MOD_Plk_4 294 300 PF00069 0.469
MOD_Plk_4 345 351 PF00069 0.469
MOD_Plk_4 399 405 PF00069 0.479
MOD_Plk_4 501 507 PF00069 0.495
MOD_Plk_4 52 58 PF00069 0.493
MOD_Plk_4 655 661 PF00069 0.475
MOD_Plk_4 72 78 PF00069 0.472
MOD_Plk_4 81 87 PF00069 0.470
MOD_Plk_4 902 908 PF00069 0.552
MOD_Plk_4 915 921 PF00069 0.562
MOD_ProDKin_1 115 121 PF00069 0.627
MOD_ProDKin_1 1184 1190 PF00069 0.518
MOD_ProDKin_1 1198 1204 PF00069 0.566
MOD_ProDKin_1 1247 1253 PF00069 0.592
MOD_ProDKin_1 1337 1343 PF00069 0.563
MOD_ProDKin_1 1352 1358 PF00069 0.495
MOD_ProDKin_1 1372 1378 PF00069 0.550
MOD_ProDKin_1 1450 1456 PF00069 0.577
MOD_ProDKin_1 1507 1513 PF00069 0.508
MOD_ProDKin_1 1548 1554 PF00069 0.531
MOD_ProDKin_1 1633 1639 PF00069 0.568
MOD_ProDKin_1 298 304 PF00069 0.469
MOD_ProDKin_1 350 356 PF00069 0.469
MOD_ProDKin_1 408 414 PF00069 0.469
MOD_ProDKin_1 471 477 PF00069 0.383
MOD_ProDKin_1 58 64 PF00069 0.543
MOD_ProDKin_1 649 655 PF00069 0.430
MOD_ProDKin_1 725 731 PF00069 0.633
MOD_ProDKin_1 76 82 PF00069 0.536
MOD_ProDKin_1 774 780 PF00069 0.457
MOD_ProDKin_1 913 919 PF00069 0.537
MOD_ProDKin_1 922 928 PF00069 0.572
MOD_SUMO_rev_2 1102 1112 PF00179 0.479
TRG_DiLeu_BaEn_1 1021 1026 PF01217 0.469
TRG_DiLeu_BaEn_1 1444 1449 PF01217 0.567
TRG_DiLeu_BaLyEn_6 1355 1360 PF01217 0.596
TRG_DiLeu_BaLyEn_6 299 304 PF01217 0.469
TRG_DiLeu_BaLyEn_6 585 590 PF01217 0.469
TRG_ENDOCYTIC_2 1039 1042 PF00928 0.469
TRG_ENDOCYTIC_2 1087 1090 PF00928 0.330
TRG_ENDOCYTIC_2 1092 1095 PF00928 0.355
TRG_ENDOCYTIC_2 1284 1287 PF00928 0.531
TRG_ENDOCYTIC_2 312 315 PF00928 0.469
TRG_ENDOCYTIC_2 398 401 PF00928 0.469
TRG_ENDOCYTIC_2 690 693 PF00928 0.418
TRG_ER_diArg_1 1 3 PF00400 0.422
TRG_ER_diArg_1 1116 1119 PF00400 0.487
TRG_ER_diArg_1 1220 1223 PF00400 0.513
TRG_ER_diArg_1 240 242 PF00400 0.377
TRG_ER_diArg_1 497 499 PF00400 0.469
TRG_ER_diArg_1 617 619 PF00400 0.469
TRG_ER_diArg_1 721 724 PF00400 0.532
TRG_ER_diArg_1 796 799 PF00400 0.445
TRG_ER_diArg_1 940 943 PF00400 0.592
TRG_ER_diArg_1 972 975 PF00400 0.627
TRG_NES_CRM1_1 239 252 PF08389 0.352
TRG_NES_CRM1_1 526 542 PF08389 0.469
TRG_NLS_MonoExtC_3 865 870 PF00514 0.573
TRG_NLS_MonoExtC_3 972 977 PF00514 0.622
TRG_NLS_MonoExtN_4 863 870 PF00514 0.580
TRG_NLS_MonoExtN_4 971 978 PF00514 0.620
TRG_Pf-PMV_PEXEL_1 1629 1633 PF00026 0.587
TRG_Pf-PMV_PEXEL_1 334 338 PF00026 0.269
TRG_Pf-PMV_PEXEL_1 6 10 PF00026 0.569
TRG_Pf-PMV_PEXEL_1 745 749 PF00026 0.379

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P880 Leptomonas seymouri 53% 84%
A4HDI8 Leishmania braziliensis 76% 100%
A4I0Z1 Leishmania infantum 100% 100%
E9AWZ8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4QAH8 Leishmania major 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS