Condensin complex subunit 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IC40_LEIDO

TriTrypDb:

LdBPK_220180.1 , LdCL_220007900 , LDHU3_22.0450

Length:

561

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 4
Pissara et al.	yes	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IC40

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IC40

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	122	124	PF00675	0.630
CLV_NRD_NRD_1	247	249	PF00675	0.651
CLV_NRD_NRD_1	4	6	PF00675	0.776
CLV_NRD_NRD_1	411	413	PF00675	0.596
CLV_NRD_NRD_1	538	540	PF00675	0.889
CLV_NRD_NRD_1	553	555	PF00675	0.896
CLV_NRD_NRD_1	556	558	PF00675	0.877
CLV_PCSK_FUR_1	554	558	PF00082	0.821
CLV_PCSK_KEX2_1	4	6	PF00082	0.776
CLV_PCSK_KEX2_1	413	415	PF00082	0.662
CLV_PCSK_KEX2_1	482	484	PF00082	0.636
CLV_PCSK_KEX2_1	504	506	PF00082	0.772
CLV_PCSK_KEX2_1	529	531	PF00082	0.790
CLV_PCSK_KEX2_1	540	542	PF00082	0.860
CLV_PCSK_KEX2_1	553	555	PF00082	0.844
CLV_PCSK_KEX2_1	556	558	PF00082	0.802
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.776
CLV_PCSK_PC1ET2_1	413	415	PF00082	0.662
CLV_PCSK_PC1ET2_1	482	484	PF00082	0.636
CLV_PCSK_PC1ET2_1	504	506	PF00082	0.772
CLV_PCSK_PC1ET2_1	529	531	PF00082	0.808
CLV_PCSK_PC1ET2_1	540	542	PF00082	0.869
CLV_PCSK_SKI1_1	124	128	PF00082	0.499
CLV_PCSK_SKI1_1	181	185	PF00082	0.644
CLV_PCSK_SKI1_1	205	209	PF00082	0.567
CLV_PCSK_SKI1_1	356	360	PF00082	0.483
CLV_PCSK_SKI1_1	363	367	PF00082	0.483
CLV_PCSK_SKI1_1	473	477	PF00082	0.560
DEG_APCC_DBOX_1	204	212	PF00400	0.581
DEG_APCC_DBOX_1	482	490	PF00400	0.700
DEG_SPOP_SBC_1	57	61	PF00917	0.707
DOC_CDC14_PxL_1	328	336	PF14671	0.551
DOC_CKS1_1	95	100	PF01111	0.636
DOC_CYCLIN_RxL_1	479	488	PF00134	0.683
DOC_MAPK_RevD_3	398	414	PF00069	0.587
DOC_PP1_RVXF_1	100	106	PF00149	0.487
DOC_PP1_RVXF_1	208	215	PF00149	0.482
DOC_PP1_RVXF_1	441	448	PF00149	0.608
DOC_PP4_MxPP_1	514	517	PF00568	0.847
DOC_USP7_MATH_1	192	196	PF00917	0.545
DOC_USP7_MATH_1	203	207	PF00917	0.498
DOC_USP7_MATH_1	452	456	PF00917	0.688
DOC_USP7_MATH_1	465	469	PF00917	0.646
DOC_USP7_MATH_1	91	95	PF00917	0.664
DOC_USP7_UBL2_3	6	10	PF12436	0.839
DOC_WW_Pin1_4	136	141	PF00397	0.566
DOC_WW_Pin1_4	9	14	PF00397	0.883
DOC_WW_Pin1_4	94	99	PF00397	0.607
LIG_14-3-3_CanoR_1	123	133	PF00244	0.619
LIG_14-3-3_CanoR_1	248	258	PF00244	0.687
LIG_14-3-3_CanoR_1	265	271	PF00244	0.402
LIG_14-3-3_CanoR_1	280	287	PF00244	0.492
LIG_14-3-3_CanoR_1	379	385	PF00244	0.599
LIG_14-3-3_CanoR_1	389	398	PF00244	0.596
LIG_14-3-3_CanoR_1	412	419	PF00244	0.610
LIG_14-3-3_CanoR_1	530	537	PF00244	0.878
LIG_Actin_WH2_2	109	125	PF00022	0.605
LIG_BIR_II_1	1	5	PF00653	0.754
LIG_BIR_III_2	182	186	PF00653	0.681
LIG_BRCT_BRCA1_1	200	204	PF00533	0.584
LIG_BRCT_BRCA1_1	324	328	PF00533	0.576
LIG_Clathr_ClatBox_1	397	401	PF01394	0.581
LIG_FHA_1	125	131	PF00498	0.510
LIG_FHA_1	137	143	PF00498	0.495
LIG_FHA_1	237	243	PF00498	0.591
LIG_FHA_1	26	32	PF00498	0.789
LIG_FHA_1	267	273	PF00498	0.597
LIG_FHA_1	280	286	PF00498	0.558
LIG_FHA_1	352	358	PF00498	0.553
LIG_FHA_1	392	398	PF00498	0.641
LIG_FHA_1	58	64	PF00498	0.509
LIG_FHA_1	95	101	PF00498	0.608
LIG_FHA_2	338	344	PF00498	0.589
LIG_FHA_2	472	478	PF00498	0.590
LIG_LIR_Apic_2	255	261	PF02991	0.639
LIG_LIR_Gen_1	160	171	PF02991	0.527
LIG_LIR_Gen_1	274	283	PF02991	0.493
LIG_LIR_Gen_1	61	71	PF02991	0.513
LIG_LIR_Nem_3	160	166	PF02991	0.551
LIG_LIR_Nem_3	201	207	PF02991	0.489
LIG_LIR_Nem_3	274	278	PF02991	0.492
LIG_LIR_Nem_3	325	331	PF02991	0.573
LIG_LIR_Nem_3	371	377	PF02991	0.490
LIG_LIR_Nem_3	440	445	PF02991	0.664
LIG_LIR_Nem_3	61	67	PF02991	0.524
LIG_LRP6_Inhibitor_1	467	473	PF00058	0.652
LIG_LYPXL_S_1	330	334	PF13949	0.524
LIG_LYPXL_S_1	373	377	PF13949	0.586
LIG_LYPXL_yS_3	331	334	PF13949	0.530
LIG_LYPXL_yS_3	374	377	PF13949	0.591
LIG_MYND_3	294	298	PF01753	0.590
LIG_NRBOX	207	213	PF00104	0.582
LIG_NRP_CendR_1	560	561	PF00754	0.861
LIG_PCNA_yPIPBox_3	117	126	PF02747	0.615
LIG_PCNA_yPIPBox_3	291	300	PF02747	0.611
LIG_RPA_C_Fungi	407	419	PF08784	0.643
LIG_SH2_CRK	378	382	PF00017	0.530
LIG_SH2_CRK	442	446	PF00017	0.665
LIG_SH2_CRK	64	68	PF00017	0.535
LIG_SH2_SRC	258	261	PF00017	0.637
LIG_SH2_STAT3	81	84	PF00017	0.612
LIG_SH2_STAT5	165	168	PF00017	0.478
LIG_SH2_STAT5	300	303	PF00017	0.599
LIG_SH2_STAT5	376	379	PF00017	0.565
LIG_SH2_STAT5	81	84	PF00017	0.612
LIG_SH3_3	47	53	PF00018	0.784
LIG_SH3_3	512	518	PF00018	0.764
LIG_SH3_3	92	98	PF00018	0.543
LIG_SUMO_SIM_anti_2	313	319	PF11976	0.486
LIG_SUMO_SIM_par_1	154	160	PF11976	0.560
LIG_SUMO_SIM_par_1	268	274	PF11976	0.538
LIG_SUMO_SIM_par_1	356	362	PF11976	0.614
LIG_SUMO_SIM_par_1	380	387	PF11976	0.581
LIG_SUMO_SIM_par_1	396	401	PF11976	0.560
LIG_TRAF2_1	14	17	PF00917	0.841
LIG_TRAF2_1	38	41	PF00917	0.828
LIG_TRFH_1	328	332	PF08558	0.508
MOD_CK1_1	195	201	PF00069	0.574
MOD_CK1_1	348	354	PF00069	0.669
MOD_CK1_1	383	389	PF00069	0.645
MOD_CK1_1	430	436	PF00069	0.589
MOD_CK1_1	69	75	PF00069	0.665
MOD_CK1_1	9	15	PF00069	0.866
MOD_CK1_1	94	100	PF00069	0.653
MOD_CK2_1	471	477	PF00069	0.587
MOD_CK2_1	56	62	PF00069	0.619
MOD_Cter_Amidation	526	529	PF01082	0.886
MOD_Cter_Amidation	558	561	PF01082	0.875
MOD_GlcNHglycan	201	204	PF01048	0.590
MOD_GlcNHglycan	414	417	PF01048	0.615
MOD_GlcNHglycan	429	432	PF01048	0.510
MOD_GlcNHglycan	461	464	PF01048	0.619
MOD_GSK3_1	195	202	PF00069	0.516
MOD_GSK3_1	344	351	PF00069	0.705
MOD_GSK3_1	359	366	PF00069	0.501
MOD_GSK3_1	423	430	PF00069	0.608
MOD_GSK3_1	58	65	PF00069	0.636
MOD_N-GLC_1	25	30	PF02516	0.794
MOD_N-GLC_1	427	432	PF02516	0.645
MOD_NEK2_1	199	204	PF00069	0.534
MOD_NEK2_1	359	364	PF00069	0.581
MOD_NEK2_1	388	393	PF00069	0.631
MOD_NEK2_1	427	432	PF00069	0.599
MOD_PIKK_1	243	249	PF00454	0.607
MOD_PIKK_1	252	258	PF00454	0.591
MOD_PIKK_1	530	536	PF00454	0.897
MOD_PIKK_1	62	68	PF00454	0.629
MOD_PKA_1	412	418	PF00069	0.638
MOD_PKA_1	528	534	PF00069	0.863
MOD_PKA_2	236	242	PF00069	0.593
MOD_PKA_2	279	285	PF00069	0.635
MOD_PKA_2	388	394	PF00069	0.636
MOD_PKA_2	529	535	PF00069	0.885
MOD_PKA_2	552	558	PF00069	0.863
MOD_Plk_1	252	258	PF00069	0.687
MOD_Plk_1	32	38	PF00069	0.662
MOD_Plk_1	423	429	PF00069	0.620
MOD_Plk_4	125	131	PF00069	0.512
MOD_Plk_4	154	160	PF00069	0.541
MOD_Plk_4	380	386	PF00069	0.609
MOD_Plk_4	66	72	PF00069	0.581
MOD_ProDKin_1	136	142	PF00069	0.556
MOD_ProDKin_1	9	15	PF00069	0.881
MOD_ProDKin_1	94	100	PF00069	0.609
MOD_SUMO_rev_2	532	542	PF00179	0.908
TRG_DiLeu_BaEn_1	96	101	PF01217	0.574
TRG_DiLeu_BaLyEn_6	237	242	PF01217	0.568
TRG_DiLeu_BaLyEn_6	258	263	PF01217	0.628
TRG_DiLeu_BaLyEn_6	292	297	PF01217	0.509
TRG_ENDOCYTIC_2	331	334	PF00928	0.545
TRG_ENDOCYTIC_2	374	377	PF00928	0.490
TRG_ENDOCYTIC_2	378	381	PF00928	0.488
TRG_ENDOCYTIC_2	442	445	PF00928	0.671
TRG_ENDOCYTIC_2	64	67	PF00928	0.529
TRG_ER_diArg_1	101	104	PF00400	0.474
TRG_ER_diArg_1	553	556	PF00400	0.804
TRG_NES_CRM1_1	260	274	PF08389	0.600
TRG_NES_CRM1_1	277	290	PF08389	0.471
TRG_NLS_Bipartite_1	528	544	PF00514	0.873
TRG_NLS_MonoExtC_3	411	417	PF00514	0.633
TRG_NLS_MonoExtC_3	539	545	PF00514	0.847
TRG_NLS_MonoExtN_4	3	8	PF00514	0.735
TRG_NLS_MonoExtN_4	537	544	PF00514	0.835

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4V0	Leptomonas seymouri	66%	95%
A0A0S4JSH7	Bodo saltans	30%	100%
A0A1X0NTF0	Trypanosomatidae	41%	99%
A0A3R7NVM0	Trypanosoma rangeli	42%	100%
A4HC80	Leishmania braziliensis	84%	100%
A4HZQ8	Leishmania infantum	100%	100%
C9ZSF1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9AVL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QBW5	Leishmania major	95%	100%
V5BFQ6	Trypanosoma cruzi	42%	100%