LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IBZ2_LEIDO
TriTrypDb:
LdBPK_260091.1 , LdCL_260005800 , LdCL_260006100 , LdCL_260006400 , LDHU3_26.0120 , LDHU3_26.0160
Length:
77

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBZ2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBZ2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 26 30 PF00656 0.568
CLV_NRD_NRD_1 11 13 PF00675 0.609
CLV_NRD_NRD_1 33 35 PF00675 0.522
CLV_PCSK_FUR_1 9 13 PF00082 0.583
CLV_PCSK_KEX2_1 11 13 PF00082 0.587
CLV_PCSK_KEX2_1 16 18 PF00082 0.559
CLV_PCSK_KEX2_1 35 37 PF00082 0.529
CLV_PCSK_PC1ET2_1 11 13 PF00082 0.551
CLV_PCSK_PC1ET2_1 16 18 PF00082 0.524
CLV_PCSK_PC1ET2_1 35 37 PF00082 0.529
CLV_PCSK_PC7_1 12 18 PF00082 0.580
CLV_PCSK_SKI1_1 25 29 PF00082 0.583
CLV_PCSK_SKI1_1 39 43 PF00082 0.436
DEG_APCC_DBOX_1 38 46 PF00400 0.621
DOC_CYCLIN_yCln2_LP_2 45 48 PF00134 0.506
DOC_PP1_SILK_1 39 44 PF00149 0.589
DOC_PP2B_LxvP_1 45 48 PF13499 0.506
DOC_USP7_MATH_1 58 62 PF00917 0.660
DOC_USP7_UBL2_3 49 53 PF12436 0.549
DOC_USP7_UBL2_3 7 11 PF12436 0.551
LIG_14-3-3_CanoR_1 17 27 PF00244 0.590
LIG_FHA_2 19 25 PF00498 0.559
LIG_UBA3_1 41 49 PF00899 0.581
MOD_CK2_1 18 24 PF00069 0.502
MOD_Cter_Amidation 32 35 PF01082 0.584
MOD_Cter_Amidation 70 73 PF01082 0.584
MOD_GlcNHglycan 60 63 PF01048 0.628
MOD_GSK3_1 23 30 PF00069 0.594
MOD_NEK2_1 23 28 PF00069 0.527
MOD_PK_1 37 43 PF00069 0.567
MOD_PKA_1 12 18 PF00069 0.562
MOD_Plk_1 23 29 PF00069 0.566
MOD_Plk_1 37 43 PF00069 0.566
TRG_NLS_MonoCore_2 10 15 PF00514 0.564
TRG_NLS_MonoExtC_3 11 16 PF00514 0.541
TRG_NLS_MonoExtN_4 69 76 PF00514 0.618
TRG_NLS_MonoExtN_4 9 16 PF00514 0.544
TRG_Pf-PMV_PEXEL_1 25 29 PF00026 0.569

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3K4 Leptomonas seymouri 86% 100%
A0A0S4IJI0 Bodo saltans 69% 81%
A0A381MJV1 Leishmania infantum 100% 100%
A4HEL5 Leishmania braziliensis 88% 100%
C9ZS75 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 60% 81%
E9AXZ1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q4Q9I1 Leishmania major 96% 100%
V5DR93 Trypanosoma cruzi 68% 80%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS