Ubiquitin-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8IBY8_LEIDO

TriTrypDb:

LdBPK_240210.1 , LdCL_240007000 , LDHU3_24.0250

Length:

340

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBY8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBY8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	17	21	PF00656	0.633
CLV_MEL_PAP_1	36	42	PF00089	0.492
CLV_NRD_NRD_1	146	148	PF00675	0.744
CLV_NRD_NRD_1	195	197	PF00675	0.525
CLV_PCSK_KEX2_1	146	148	PF00082	0.719
CLV_PCSK_SKI1_1	139	143	PF00082	0.671
CLV_PCSK_SKI1_1	318	322	PF00082	0.763
CLV_PCSK_SKI1_1	6	10	PF00082	0.556
DEG_Nend_UBRbox_1	1	4	PF02207	0.417
DOC_CKS1_1	220	225	PF01111	0.619
DOC_CKS1_1	273	278	PF01111	0.546
DOC_CYCLIN_yCln2_LP_2	273	279	PF00134	0.538
DOC_MAPK_gen_1	272	279	PF00069	0.548
DOC_MAPK_MEF2A_6	221	229	PF00069	0.377
DOC_MAPK_MEF2A_6	33	40	PF00069	0.493
DOC_MAPK_RevD_3	131	147	PF00069	0.715
DOC_PP2B_LxvP_1	133	136	PF13499	0.671
DOC_USP7_UBL2_3	115	119	PF12436	0.666
DOC_WW_Pin1_4	21	26	PF00397	0.567
DOC_WW_Pin1_4	219	224	PF00397	0.584
DOC_WW_Pin1_4	272	277	PF00397	0.554
LIG_14-3-3_CanoR_1	12	16	PF00244	0.422
LIG_14-3-3_CanoR_1	2	6	PF00244	0.550
LIG_14-3-3_CanoR_1	39	49	PF00244	0.527
LIG_AP2alpha_2	224	226	PF02296	0.693
LIG_BIR_III_4	152	156	PF00653	0.806
LIG_Clathr_ClatBox_1	48	52	PF01394	0.556
LIG_FHA_1	56	62	PF00498	0.612
LIG_FHA_1	74	80	PF00498	0.335
LIG_FHA_2	26	32	PF00498	0.487
LIG_FHA_2	94	100	PF00498	0.648
LIG_FXI_DFP_1	245	249	PF00024	0.581
LIG_G3BP_FGDF_1	243	248	PF02136	0.463
LIG_LIR_Gen_1	10	21	PF02991	0.613
LIG_LIR_Gen_1	182	193	PF02991	0.586
LIG_LIR_Gen_1	224	234	PF02991	0.614
LIG_LIR_Gen_1	247	255	PF02991	0.481
LIG_LIR_Gen_1	305	314	PF02991	0.501
LIG_LIR_Nem_3	10	16	PF02991	0.599
LIG_LIR_Nem_3	182	188	PF02991	0.522
LIG_LIR_Nem_3	224	229	PF02991	0.684
LIG_LIR_Nem_3	247	251	PF02991	0.459
LIG_LIR_Nem_3	305	311	PF02991	0.476
LIG_LYPXL_S_1	285	289	PF13949	0.472
LIG_LYPXL_yS_3	208	211	PF13949	0.451
LIG_LYPXL_yS_3	286	289	PF13949	0.451
LIG_NRBOX	50	56	PF00104	0.591
LIG_Pex14_2	307	311	PF04695	0.520
LIG_SH2_CRK	185	189	PF00017	0.572
LIG_SH2_NCK_1	13	17	PF00017	0.579
LIG_SH2_SRC	185	188	PF00017	0.587
LIG_SH2_STAT5	244	247	PF00017	0.470
LIG_SH3_3	118	124	PF00018	0.655
LIG_SH3_3	156	162	PF00018	0.717
LIG_SH3_3	208	214	PF00018	0.512
LIG_SH3_3	67	73	PF00018	0.565
LIG_SUMO_SIM_anti_2	46	52	PF11976	0.468
LIG_SUMO_SIM_anti_2	63	68	PF11976	0.485
LIG_SUMO_SIM_par_1	291	297	PF11976	0.441
LIG_SUMO_SIM_par_1	46	52	PF11976	0.546
LIG_SUMO_SIM_par_1	56	63	PF11976	0.567
LIG_TYR_ITIM	206	211	PF00017	0.442
LIG_UBA3_1	111	119	PF00899	0.584
MOD_CK1_1	24	30	PF00069	0.536
MOD_CK1_1	264	270	PF00069	0.517
MOD_CK2_1	11	17	PF00069	0.525
MOD_CK2_1	25	31	PF00069	0.388
MOD_CK2_1	40	46	PF00069	0.488
MOD_CK2_1	80	86	PF00069	0.669
MOD_GlcNHglycan	315	318	PF01048	0.695
MOD_GlcNHglycan	331	334	PF01048	0.653
MOD_GSK3_1	21	28	PF00069	0.474
MOD_GSK3_1	7	14	PF00069	0.485
MOD_NEK2_1	1	6	PF00069	0.549
MOD_NEK2_1	40	45	PF00069	0.522
MOD_NEK2_1	55	60	PF00069	0.541
MOD_NEK2_1	85	90	PF00069	0.696
MOD_PK_1	62	68	PF00069	0.558
MOD_PKA_2	1	7	PF00069	0.550
MOD_PKA_2	11	17	PF00069	0.433
MOD_PKA_2	80	86	PF00069	0.599
MOD_Plk_1	25	31	PF00069	0.590
MOD_Plk_1	55	61	PF00069	0.551
MOD_Plk_4	11	17	PF00069	0.465
MOD_Plk_4	62	68	PF00069	0.563
MOD_Plk_4	80	86	PF00069	0.471
MOD_ProDKin_1	21	27	PF00069	0.559
MOD_ProDKin_1	219	225	PF00069	0.599
MOD_ProDKin_1	272	278	PF00069	0.555
MOD_SUMO_rev_2	26	35	PF00179	0.509
TRG_DiLeu_BaEn_1	31	36	PF01217	0.473
TRG_DiLeu_BaLyEn_6	284	289	PF01217	0.569
TRG_ENDOCYTIC_2	13	16	PF00928	0.570
TRG_ENDOCYTIC_2	185	188	PF00928	0.517
TRG_ENDOCYTIC_2	208	211	PF00928	0.451
TRG_ENDOCYTIC_2	286	289	PF00928	0.451
TRG_ER_diArg_1	136	139	PF00400	0.625
TRG_ER_diArg_1	271	274	PF00400	0.550

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7K8	Leptomonas seymouri	68%	100%
A0A0S4JUQ7	Bodo saltans	38%	100%
A0A1X0NIQ0	Trypanosomatidae	47%	100%
E9AH33	Leishmania infantum	99%	100%
E9AWL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QAV9	Leishmania major	94%	100%