ABC transporter, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ABC transporter, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IBV9_LEIDO

TriTrypDb:

LdBPK_211070.1 , LdCL_210015700 , LDHU3_21.1270

Length:

951

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

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Expansion

Sequence features

A0A3Q8IBV9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBV9

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0005215	transporter activity	1	5
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0015399	primary active transmembrane transporter activity	4	5
GO:0017076	purine nucleotide binding	4	7
GO:0022804	active transmembrane transporter activity	3	5
GO:0022857	transmembrane transporter activity	2	5
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	20	24	PF00656	0.780
CLV_C14_Caspase3-7	295	299	PF00656	0.682
CLV_C14_Caspase3-7	480	484	PF00656	0.693
CLV_C14_Caspase3-7	539	543	PF00656	0.775
CLV_C14_Caspase3-7	563	567	PF00656	0.704
CLV_NRD_NRD_1	252	254	PF00675	0.346
CLV_NRD_NRD_1	302	304	PF00675	0.432
CLV_NRD_NRD_1	467	469	PF00675	0.559
CLV_NRD_NRD_1	687	689	PF00675	0.326
CLV_NRD_NRD_1	74	76	PF00675	0.561

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8B6	Leptomonas seymouri	55%	99%
A4HBU5	Leishmania braziliensis	72%	100%
E9AGV1	Leishmania infantum	100%	100%
E9AV67	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4QCB4	Leishmania major	92%	100%

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