LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8IBR5_LEIDO
TriTrypDb:
LdBPK_201060.1 * , LdCL_200015300 , LDHU3_20.1320
Length:
956

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBR5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBR5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 300 304 PF00656 0.775
CLV_C14_Caspase3-7 369 373 PF00656 0.767
CLV_C14_Caspase3-7 526 530 PF00656 0.830
CLV_C14_Caspase3-7 531 535 PF00656 0.766
CLV_C14_Caspase3-7 539 543 PF00656 0.625
CLV_C14_Caspase3-7 803 807 PF00656 0.701
CLV_NRD_NRD_1 290 292 PF00675 0.776
CLV_NRD_NRD_1 293 295 PF00675 0.734
CLV_NRD_NRD_1 316 318 PF00675 0.755
CLV_NRD_NRD_1 387 389 PF00675 0.786
CLV_NRD_NRD_1 551 553 PF00675 0.769
CLV_NRD_NRD_1 690 692 PF00675 0.833
CLV_NRD_NRD_1 748 750 PF00675 0.741
CLV_NRD_NRD_1 881 883 PF00675 0.697
CLV_NRD_NRD_1 911 913 PF00675 0.750
CLV_PCSK_FUR_1 291 295 PF00082 0.704
CLV_PCSK_KEX2_1 292 294 PF00082 0.778
CLV_PCSK_KEX2_1 316 318 PF00082 0.755
CLV_PCSK_KEX2_1 551 553 PF00082 0.832
CLV_PCSK_KEX2_1 690 692 PF00082 0.833
CLV_PCSK_KEX2_1 748 750 PF00082 0.741
CLV_PCSK_KEX2_1 911 913 PF00082 0.750
CLV_PCSK_PC1ET2_1 292 294 PF00082 0.778
CLV_PCSK_SKI1_1 223 227 PF00082 0.751
CLV_PCSK_SKI1_1 437 441 PF00082 0.645
CLV_PCSK_SKI1_1 567 571 PF00082 0.838
CLV_PCSK_SKI1_1 844 848 PF00082 0.616
CLV_PCSK_SKI1_1 882 886 PF00082 0.698
CLV_PCSK_SKI1_1 944 948 PF00082 0.738
CLV_Separin_Metazoa 220 224 PF03568 0.742
DEG_Nend_UBRbox_3 1 3 PF02207 0.721
DEG_SCF_FBW7_1 895 901 PF00400 0.818
DEG_SCF_FBW7_2 72 77 PF00400 0.799
DEG_SPOP_SBC_1 361 365 PF00917 0.768
DEG_SPOP_SBC_1 485 489 PF00917 0.833
DOC_ANK_TNKS_1 194 201 PF00023 0.647
DOC_ANK_TNKS_1 315 322 PF00023 0.738
DOC_CKS1_1 895 900 PF01111 0.820
DOC_CYCLIN_RxL_1 841 849 PF00134 0.606
DOC_MAPK_gen_1 268 278 PF00069 0.666
DOC_PP4_FxxP_1 278 281 PF00568 0.817
DOC_USP7_MATH_1 260 264 PF00917 0.775
DOC_USP7_MATH_1 281 285 PF00917 0.666
DOC_USP7_MATH_1 33 37 PF00917 0.827
DOC_USP7_MATH_1 361 365 PF00917 0.768
DOC_USP7_MATH_1 486 490 PF00917 0.790
DOC_USP7_MATH_1 536 540 PF00917 0.698
DOC_USP7_MATH_1 544 548 PF00917 0.641
DOC_USP7_MATH_1 596 600 PF00917 0.742
DOC_USP7_MATH_1 653 657 PF00917 0.763
DOC_USP7_MATH_1 66 70 PF00917 0.792
DOC_USP7_MATH_1 675 679 PF00917 0.743
DOC_USP7_MATH_1 716 720 PF00917 0.756
DOC_USP7_MATH_1 738 742 PF00917 0.775
DOC_USP7_MATH_1 764 768 PF00917 0.757
DOC_USP7_MATH_1 783 787 PF00917 0.627
DOC_USP7_MATH_1 835 839 PF00917 0.655
DOC_USP7_MATH_1 842 846 PF00917 0.615
DOC_USP7_MATH_1 856 860 PF00917 0.694
DOC_USP7_MATH_1 929 933 PF00917 0.750
DOC_USP7_UBL2_3 288 292 PF12436 0.498
DOC_WW_Pin1_4 224 229 PF00397 0.743
DOC_WW_Pin1_4 344 349 PF00397 0.826
DOC_WW_Pin1_4 362 367 PF00397 0.540
DOC_WW_Pin1_4 399 404 PF00397 0.797
DOC_WW_Pin1_4 421 426 PF00397 0.747
DOC_WW_Pin1_4 64 69 PF00397 0.798
DOC_WW_Pin1_4 646 651 PF00397 0.854
DOC_WW_Pin1_4 70 75 PF00397 0.841
DOC_WW_Pin1_4 706 711 PF00397 0.669
DOC_WW_Pin1_4 779 784 PF00397 0.756
DOC_WW_Pin1_4 894 899 PF00397 0.814
DOC_WW_Pin1_4 919 924 PF00397 0.772
DOC_WW_Pin1_4 931 936 PF00397 0.715
LIG_14-3-3_CanoR_1 223 228 PF00244 0.744
LIG_14-3-3_CanoR_1 244 249 PF00244 0.803
LIG_14-3-3_CanoR_1 395 405 PF00244 0.800
LIG_14-3-3_CanoR_1 437 442 PF00244 0.643
LIG_14-3-3_CanoR_1 537 545 PF00244 0.642
LIG_14-3-3_CanoR_1 660 666 PF00244 0.785
LIG_14-3-3_CanoR_1 748 753 PF00244 0.821
LIG_14-3-3_CanoR_1 819 825 PF00244 0.709
LIG_14-3-3_CanoR_1 860 868 PF00244 0.663
LIG_APCC_ABBA_1 798 803 PF00400 0.757
LIG_BRCT_BRCA1_1 401 405 PF00533 0.791
LIG_BRCT_BRCA1_1 514 518 PF00533 0.847
LIG_EH_1 177 181 PF12763 0.820
LIG_FHA_1 138 144 PF00498 0.834
LIG_FHA_1 216 222 PF00498 0.853
LIG_FHA_1 253 259 PF00498 0.636
LIG_FHA_1 271 277 PF00498 0.731
LIG_FHA_1 454 460 PF00498 0.644
LIG_FHA_1 681 687 PF00498 0.761
LIG_FHA_1 895 901 PF00498 0.732
LIG_FHA_1 932 938 PF00498 0.784
LIG_FHA_2 185 191 PF00498 0.771
LIG_FHA_2 224 230 PF00498 0.783
LIG_FHA_2 300 306 PF00498 0.699
LIG_FHA_2 753 759 PF00498 0.824
LIG_FHA_2 821 827 PF00498 0.610
LIG_GSK3_LRP6_1 646 651 PF00069 0.743
LIG_LIR_Apic_2 22 27 PF02991 0.784
LIG_LIR_Apic_2 277 281 PF02991 0.808
LIG_LIR_Apic_2 36 41 PF02991 0.652
LIG_LIR_Apic_2 948 954 PF02991 0.804
LIG_LIR_Gen_1 247 252 PF02991 0.835
LIG_LIR_Gen_1 330 339 PF02991 0.744
LIG_LIR_Gen_1 572 583 PF02991 0.751
LIG_LIR_Gen_1 762 773 PF02991 0.681
LIG_LIR_Gen_1 945 954 PF02991 0.808
LIG_LIR_Nem_3 247 251 PF02991 0.834
LIG_LIR_Nem_3 277 282 PF02991 0.667
LIG_LIR_Nem_3 330 336 PF02991 0.744
LIG_LIR_Nem_3 404 409 PF02991 0.568
LIG_LIR_Nem_3 53 57 PF02991 0.815
LIG_LIR_Nem_3 762 768 PF02991 0.727
LIG_LIR_Nem_3 822 827 PF02991 0.794
LIG_LIR_Nem_3 945 949 PF02991 0.815
LIG_MAD2 343 351 PF02301 0.615
LIG_MLH1_MIPbox_1 403 407 PF16413 0.783
LIG_MYND_1 348 352 PF01753 0.772
LIG_SH2_CRK 24 28 PF00017 0.756
LIG_SH2_CRK 279 283 PF00017 0.811
LIG_SH2_CRK 951 955 PF00017 0.602
LIG_SH2_STAP1 248 252 PF00017 0.836
LIG_SH2_STAP1 409 413 PF00017 0.553
LIG_SH2_STAP1 752 756 PF00017 0.753
LIG_SH2_STAT5 406 409 PF00017 0.781
LIG_SH2_STAT5 54 57 PF00017 0.756
LIG_SH2_STAT5 892 895 PF00017 0.815
LIG_SH3_1 892 898 PF00018 0.814
LIG_SH3_2 877 882 PF14604 0.620
LIG_SH3_3 156 162 PF00018 0.730
LIG_SH3_3 193 199 PF00018 0.785
LIG_SH3_3 342 348 PF00018 0.807
LIG_SH3_3 60 66 PF00018 0.846
LIG_SH3_3 641 647 PF00018 0.843
LIG_SH3_3 865 871 PF00018 0.735
LIG_SH3_3 874 880 PF00018 0.643
LIG_SH3_3 892 898 PF00018 0.744
LIG_SUMO_SIM_anti_2 335 340 PF11976 0.671
LIG_TRAF2_1 41 44 PF00917 0.732
LIG_TRAF2_1 74 77 PF00917 0.798
MOD_CDK_SPK_2 344 349 PF00069 0.748
MOD_CDK_SPK_2 70 75 PF00069 0.837
MOD_CDK_SPK_2 898 903 PF00069 0.756
MOD_CDK_SPxxK_3 919 926 PF00069 0.642
MOD_CK1_1 126 132 PF00069 0.760
MOD_CK1_1 142 148 PF00069 0.633
MOD_CK1_1 194 200 PF00069 0.685
MOD_CK1_1 364 370 PF00069 0.790
MOD_CK1_1 399 405 PF00069 0.794
MOD_CK1_1 487 493 PF00069 0.693
MOD_CK1_1 527 533 PF00069 0.852
MOD_CK1_1 562 568 PF00069 0.770
MOD_CK1_1 586 592 PF00069 0.820
MOD_CK1_1 651 657 PF00069 0.752
MOD_CK1_1 67 73 PF00069 0.871
MOD_CK1_1 693 699 PF00069 0.775
MOD_CK1_1 721 727 PF00069 0.639
MOD_CK1_1 804 810 PF00069 0.697
MOD_CK1_1 840 846 PF00069 0.761
MOD_CK1_1 945 951 PF00069 0.814
MOD_CK2_1 184 190 PF00069 0.770
MOD_CK2_1 223 229 PF00069 0.784
MOD_CK2_1 299 305 PF00069 0.704
MOD_CK2_1 507 513 PF00069 0.766
MOD_CK2_1 820 826 PF00069 0.611
MOD_GlcNHglycan 128 131 PF01048 0.746
MOD_GlcNHglycan 133 136 PF01048 0.716
MOD_GlcNHglycan 147 150 PF01048 0.602
MOD_GlcNHglycan 262 265 PF01048 0.742
MOD_GlcNHglycan 299 302 PF01048 0.747
MOD_GlcNHglycan 425 428 PF01048 0.744
MOD_GlcNHglycan 491 494 PF01048 0.742
MOD_GlcNHglycan 507 512 PF01048 0.637
MOD_GlcNHglycan 513 517 PF01048 0.839
MOD_GlcNHglycan 561 564 PF01048 0.825
MOD_GlcNHglycan 675 678 PF01048 0.770
MOD_GlcNHglycan 7 10 PF01048 0.784
MOD_GlcNHglycan 701 704 PF01048 0.719
MOD_GlcNHglycan 752 755 PF01048 0.785
MOD_GlcNHglycan 792 797 PF01048 0.738
MOD_GlcNHglycan 837 840 PF01048 0.620
MOD_GlcNHglycan 87 93 PF01048 0.779
MOD_GSK3_1 124 131 PF00069 0.767
MOD_GSK3_1 145 152 PF00069 0.764
MOD_GSK3_1 194 201 PF00069 0.722
MOD_GSK3_1 232 239 PF00069 0.842
MOD_GSK3_1 270 277 PF00069 0.838
MOD_GSK3_1 360 367 PF00069 0.759
MOD_GSK3_1 397 404 PF00069 0.720
MOD_GSK3_1 449 456 PF00069 0.806
MOD_GSK3_1 484 491 PF00069 0.842
MOD_GSK3_1 492 499 PF00069 0.693
MOD_GSK3_1 503 510 PF00069 0.725
MOD_GSK3_1 555 562 PF00069 0.818
MOD_GSK3_1 64 71 PF00069 0.864
MOD_GSK3_1 673 680 PF00069 0.782
MOD_GSK3_1 695 702 PF00069 0.805
MOD_GSK3_1 7 14 PF00069 0.693
MOD_GSK3_1 717 724 PF00069 0.697
MOD_GSK3_1 744 751 PF00069 0.815
MOD_GSK3_1 779 786 PF00069 0.773
MOD_GSK3_1 801 808 PF00069 0.743
MOD_GSK3_1 815 822 PF00069 0.607
MOD_GSK3_1 856 863 PF00069 0.691
MOD_GSK3_1 894 901 PF00069 0.819
MOD_LATS_1 182 188 PF00433 0.768
MOD_LATS_1 697 703 PF00433 0.567
MOD_LATS_1 858 864 PF00433 0.730
MOD_N-GLC_1 145 150 PF02516 0.763
MOD_N-GLC_1 361 366 PF02516 0.627
MOD_N-GLC_1 496 501 PF02516 0.853
MOD_N-GLC_1 578 583 PF02516 0.773
MOD_N-GLC_1 693 698 PF02516 0.850
MOD_N-GLC_1 929 934 PF02516 0.784
MOD_NEK2_1 123 128 PF00069 0.708
MOD_NEK2_1 577 582 PF00069 0.784
MOD_NEK2_1 583 588 PF00069 0.680
MOD_NEK2_1 814 819 PF00069 0.766
MOD_NEK2_1 937 942 PF00069 0.757
MOD_NEK2_2 274 279 PF00069 0.824
MOD_NEK2_2 842 847 PF00069 0.602
MOD_PIKK_1 128 134 PF00454 0.747
MOD_PIKK_1 236 242 PF00454 0.785
MOD_PIKK_1 253 259 PF00454 0.536
MOD_PIKK_1 327 333 PF00454 0.585
MOD_PIKK_1 651 657 PF00454 0.830
MOD_PIKK_1 837 843 PF00454 0.814
MOD_PK_1 124 130 PF00069 0.652
MOD_PKA_1 554 560 PF00069 0.817
MOD_PKA_1 690 696 PF00069 0.771
MOD_PKA_1 748 754 PF00069 0.745
MOD_PKA_2 123 129 PF00069 0.656
MOD_PKA_2 194 200 PF00069 0.793
MOD_PKA_2 216 222 PF00069 0.641
MOD_PKA_2 232 238 PF00069 0.552
MOD_PKA_2 270 276 PF00069 0.764
MOD_PKA_2 297 303 PF00069 0.700
MOD_PKA_2 312 318 PF00069 0.675
MOD_PKA_2 536 542 PF00069 0.770
MOD_PKA_2 659 665 PF00069 0.826
MOD_PKA_2 673 679 PF00069 0.638
MOD_PKA_2 690 696 PF00069 0.705
MOD_PKA_2 748 754 PF00069 0.745
MOD_PKA_2 804 810 PF00069 0.697
MOD_Plk_1 124 130 PF00069 0.749
MOD_Plk_1 334 340 PF00069 0.634
MOD_Plk_1 371 377 PF00069 0.604
MOD_Plk_1 43 49 PF00069 0.731
MOD_Plk_1 524 530 PF00069 0.746
MOD_Plk_1 578 584 PF00069 0.810
MOD_Plk_1 792 798 PF00069 0.743
MOD_Plk_1 805 811 PF00069 0.678
MOD_Plk_2-3 19 25 PF00069 0.641
MOD_Plk_2-3 503 509 PF00069 0.755
MOD_Plk_2-3 524 530 PF00069 0.707
MOD_Plk_4 246 252 PF00069 0.795
MOD_Plk_4 274 280 PF00069 0.737
MOD_Plk_4 334 340 PF00069 0.569
MOD_Plk_4 401 407 PF00069 0.787
MOD_Plk_4 449 455 PF00069 0.740
MOD_Plk_4 50 56 PF00069 0.812
MOD_Plk_4 578 584 PF00069 0.810
MOD_Plk_4 596 602 PF00069 0.511
MOD_Plk_4 661 667 PF00069 0.646
MOD_Plk_4 783 789 PF00069 0.698
MOD_Plk_4 842 848 PF00069 0.606
MOD_ProDKin_1 224 230 PF00069 0.743
MOD_ProDKin_1 344 350 PF00069 0.829
MOD_ProDKin_1 362 368 PF00069 0.539
MOD_ProDKin_1 399 405 PF00069 0.794
MOD_ProDKin_1 421 427 PF00069 0.748
MOD_ProDKin_1 64 70 PF00069 0.800
MOD_ProDKin_1 646 652 PF00069 0.857
MOD_ProDKin_1 706 712 PF00069 0.670
MOD_ProDKin_1 779 785 PF00069 0.760
MOD_ProDKin_1 894 900 PF00069 0.817
MOD_ProDKin_1 919 925 PF00069 0.773
MOD_ProDKin_1 931 937 PF00069 0.715
TRG_ENDOCYTIC_2 248 251 PF00928 0.835
TRG_ENDOCYTIC_2 279 282 PF00928 0.672
TRG_ENDOCYTIC_2 409 412 PF00928 0.554
TRG_ENDOCYTIC_2 54 57 PF00928 0.818
TRG_ENDOCYTIC_2 575 578 PF00928 0.830
TRG_ENDOCYTIC_2 95 98 PF00928 0.836
TRG_ER_diArg_1 183 186 PF00400 0.769
TRG_ER_diArg_1 291 294 PF00400 0.707
TRG_ER_diArg_1 316 318 PF00400 0.766
TRG_ER_diArg_1 550 552 PF00400 0.757
TRG_ER_diArg_1 690 692 PF00400 0.849
TRG_ER_diArg_1 910 912 PF00400 0.749
TRG_NLS_MonoCore_2 290 295 PF00514 0.702
TRG_NLS_MonoExtC_3 291 297 PF00514 0.773
TRG_NLS_MonoExtC_3 387 392 PF00514 0.702
TRG_NLS_MonoExtN_4 288 295 PF00514 0.630
TRG_NLS_MonoExtN_4 388 393 PF00514 0.703
TRG_NLS_MonoExtN_4 880 886 PF00514 0.596

Homologs

Protein Taxonomy Sequence identity Coverage
A4HYU6 Leishmania infantum 98% 100%
E9AIF4 Leishmania braziliensis 58% 100%
E9AUP3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 99%
Q4QCU1 Leishmania major 86% 99%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS