Guanine nucleotide-binding protein subunit beta-like protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

WD domain, G-beta repeat, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IBR2_LEIDO

TriTrypDb:

LdBPK_210100.1 , LdCL_210005900 , LDHU3_21.0110

Length:

424

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 8

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005840	ribosome	5	12
GO:0015935	small ribosomal subunit	4	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0032991	protein-containing complex	1	13
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0044391	ribosomal subunit	3	1

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Expansion

Sequence features

A0A3Q8IBR2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBR2

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0043021	ribonucleoprotein complex binding	3	1
GO:0043022	ribosome binding	4	1
GO:0044877	protein-containing complex binding	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	10	14	PF00656	0.783
CLV_PCSK_KEX2_1	311	313	PF00082	0.456
CLV_PCSK_PC1ET2_1	311	313	PF00082	0.465
CLV_PCSK_SKI1_1	110	114	PF00082	0.504
CLV_PCSK_SKI1_1	162	166	PF00082	0.284
CLV_PCSK_SKI1_1	312	316	PF00082	0.365
CLV_PCSK_SKI1_1	53	57	PF00082	0.607
CLV_PCSK_SKI1_1	85	89	PF00082	0.527
CLV_PCSK_SKI1_1	95	99	PF00082	0.474
DEG_SCF_FBW7_1	146	152	PF00400	0.521

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3X3	Leptomonas seymouri	27%	95%
A0A0N1I307	Leptomonas seymouri	66%	98%
A0A0S4J1I0	Bodo saltans	40%	94%
A0A1X0NQ96	Trypanosomatidae	23%	100%
A0A1X0NQI7	Trypanosomatidae	27%	100%
A0A1X0NYQ0	Trypanosomatidae	47%	94%
A0A3R7KUH0	Trypanosoma rangeli	24%	100%
A0A3S7WR72	Leishmania donovani	26%	100%
A0A3S7X9Q7	Leishmania donovani	26%	95%
A0A3S7XBP3	Leishmania donovani	22%	83%

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