LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IBR0_LEIDO
TriTrypDb:
LdBPK_231930.1 * , LdCL_230026500 , LDHU3_23.2530
Length:
651

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBR0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBR0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 353 357 PF00656 0.582
CLV_C14_Caspase3-7 421 425 PF00656 0.496
CLV_NRD_NRD_1 17 19 PF00675 0.612
CLV_NRD_NRD_1 193 195 PF00675 0.459
CLV_NRD_NRD_1 319 321 PF00675 0.419
CLV_PCSK_KEX2_1 17 19 PF00082 0.612
CLV_PCSK_KEX2_1 193 195 PF00082 0.459
CLV_PCSK_KEX2_1 319 321 PF00082 0.425
CLV_PCSK_KEX2_1 369 371 PF00082 0.498
CLV_PCSK_PC1ET2_1 369 371 PF00082 0.498
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IKS3 Leptomonas seymouri 53% 78%
A0A1X0NXC2 Trypanosomatidae 26% 83%
A0A3R7RJS0 Trypanosoma rangeli 28% 82%
A4HD37 Leishmania braziliensis 86% 100%
C9ZNR6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 80%
E9AH15 Leishmania infantum 100% 100%
E9AWI5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4QAY5 Leishmania major 94% 100%
V5BFS5 Trypanosoma cruzi 26% 82%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS