LeishMANIAdb
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NTP_transf_2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
NTP_transf_2 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IBI1_LEIDO
TriTrypDb:
LdBPK_191410.1 , LdCL_190019800 , LDHU3_19.1700
Length:
747

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBI1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBI1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 11 15 PF00656 0.774
CLV_C14_Caspase3-7 413 417 PF00656 0.663
CLV_NRD_NRD_1 121 123 PF00675 0.536
CLV_NRD_NRD_1 249 251 PF00675 0.716
CLV_NRD_NRD_1 276 278 PF00675 0.678
CLV_NRD_NRD_1 292 294 PF00675 0.737
CLV_NRD_NRD_1 323 325 PF00675 0.799
CLV_NRD_NRD_1 635 637 PF00675 0.717
CLV_NRD_NRD_1 88 90 PF00675 0.489
CLV_PCSK_KEX2_1 121 123 PF00082 0.536
CLV_PCSK_KEX2_1 249 251 PF00082 0.716
CLV_PCSK_KEX2_1 323 325 PF00082 0.799
CLV_PCSK_KEX2_1 408 410 PF00082 0.575
CLV_PCSK_KEX2_1 88 90 PF00082 0.489
CLV_PCSK_PC1ET2_1 408 410 PF00082 0.650
CLV_PCSK_SKI1_1 112 116 PF00082 0.483
CLV_PCSK_SKI1_1 408 412 PF00082 0.649
CLV_PCSK_SKI1_1 476 480 PF00082 0.580
CLV_PCSK_SKI1_1 630 634 PF00082 0.722
CLV_PCSK_SKI1_1 730 734 PF00082 0.587
CLV_Separin_Metazoa 246 250 PF03568 0.675
DEG_APCC_DBOX_1 111 119 PF00400 0.706
DEG_APCC_DBOX_1 467 475 PF00400 0.522
DEG_APCC_DBOX_1 508 516 PF00400 0.737
DEG_APCC_DBOX_1 527 535 PF00400 0.365
DEG_APCC_DBOX_1 578 586 PF00400 0.646
DOC_CKS1_1 462 467 PF01111 0.745
DOC_CYCLIN_RxL_1 473 481 PF00134 0.682
DOC_CYCLIN_yCln2_LP_2 735 738 PF00134 0.634
DOC_MAPK_gen_1 509 517 PF00069 0.659
DOC_MAPK_gen_1 725 734 PF00069 0.636
DOC_MAPK_MEF2A_6 25 34 PF00069 0.479
DOC_MAPK_MEF2A_6 528 536 PF00069 0.662
DOC_MAPK_MEF2A_6 579 586 PF00069 0.569
DOC_MAPK_MEF2A_6 67 76 PF00069 0.667
DOC_MAPK_MEF2A_6 728 736 PF00069 0.635
DOC_MAPK_RevD_3 106 122 PF00069 0.491
DOC_MIT_MIM_1 507 515 PF04212 0.658
DOC_PP2B_LxvP_1 286 289 PF13499 0.817
DOC_PP2B_LxvP_1 734 737 PF13499 0.627
DOC_PP2B_PxIxI_1 541 547 PF00149 0.619
DOC_USP7_MATH_1 144 148 PF00917 0.773
DOC_USP7_MATH_1 169 173 PF00917 0.824
DOC_USP7_MATH_1 175 179 PF00917 0.784
DOC_USP7_MATH_1 182 186 PF00917 0.656
DOC_USP7_MATH_1 199 203 PF00917 0.614
DOC_USP7_MATH_1 225 229 PF00917 0.775
DOC_USP7_MATH_1 300 304 PF00917 0.804
DOC_USP7_MATH_1 348 352 PF00917 0.847
DOC_USP7_MATH_1 368 372 PF00917 0.533
DOC_USP7_MATH_1 452 456 PF00917 0.728
DOC_USP7_MATH_1 667 671 PF00917 0.705
DOC_USP7_MATH_1 687 691 PF00917 0.564
DOC_USP7_MATH_1 741 745 PF00917 0.685
DOC_USP7_UBL2_3 404 408 PF12436 0.510
DOC_WW_Pin1_4 147 152 PF00397 0.808
DOC_WW_Pin1_4 165 170 PF00397 0.589
DOC_WW_Pin1_4 180 185 PF00397 0.623
DOC_WW_Pin1_4 230 235 PF00397 0.777
DOC_WW_Pin1_4 333 338 PF00397 0.855
DOC_WW_Pin1_4 378 383 PF00397 0.791
DOC_WW_Pin1_4 384 389 PF00397 0.633
DOC_WW_Pin1_4 461 466 PF00397 0.662
DOC_WW_Pin1_4 624 629 PF00397 0.718
DOC_WW_Pin1_4 691 696 PF00397 0.732
LIG_14-3-3_CanoR_1 193 203 PF00244 0.749
LIG_14-3-3_CanoR_1 335 341 PF00244 0.642
LIG_14-3-3_CanoR_1 374 380 PF00244 0.763
LIG_14-3-3_CanoR_1 476 486 PF00244 0.573
LIG_14-3-3_CanoR_1 522 532 PF00244 0.648
LIG_14-3-3_CanoR_1 547 552 PF00244 0.626
LIG_14-3-3_CanoR_1 559 565 PF00244 0.432
LIG_14-3-3_CanoR_1 649 658 PF00244 0.553
LIG_14-3-3_CanoR_1 668 676 PF00244 0.626
LIG_Actin_WH2_2 417 432 PF00022 0.699
LIG_Actin_WH2_2 533 551 PF00022 0.644
LIG_Actin_WH2_2 714 732 PF00022 0.598
LIG_APCC_ABBA_1 7 12 PF00400 0.814
LIG_BIR_II_1 1 5 PF00653 0.846
LIG_BRCT_MDC1_1 743 747 PF00533 0.731
LIG_Clathr_ClatBox_1 531 535 PF01394 0.642
LIG_CSL_BTD_1 385 388 PF09270 0.714
LIG_FHA_1 258 264 PF00498 0.842
LIG_FHA_1 27 33 PF00498 0.472
LIG_FHA_1 493 499 PF00498 0.530
LIG_FHA_1 731 737 PF00498 0.629
LIG_FHA_2 345 351 PF00498 0.677
LIG_FHA_2 445 451 PF00498 0.848
LIG_FHA_2 499 505 PF00498 0.674
LIG_GBD_Chelix_1 392 400 PF00786 0.725
LIG_GBD_Chelix_1 471 479 PF00786 0.610
LIG_Integrin_RGD_1 468 470 PF01839 0.743
LIG_LIR_Apic_2 385 389 PF02991 0.704
LIG_LIR_Gen_1 309 319 PF02991 0.586
LIG_LIR_Gen_1 57 63 PF02991 0.679
LIG_LIR_Gen_1 670 680 PF02991 0.588
LIG_LIR_Nem_3 309 315 PF02991 0.585
LIG_LIR_Nem_3 406 410 PF02991 0.658
LIG_LIR_Nem_3 484 490 PF02991 0.597
LIG_LIR_Nem_3 550 555 PF02991 0.652
LIG_LIR_Nem_3 57 62 PF02991 0.687
LIG_Pex14_2 605 609 PF04695 0.736
LIG_Pex14_2 696 700 PF04695 0.714
LIG_RPA_C_Fungi 646 658 PF08784 0.765
LIG_SH2_CRK 487 491 PF00017 0.661
LIG_SH2_SRC 518 521 PF00017 0.570
LIG_SH2_STAP1 523 527 PF00017 0.684
LIG_SH2_STAP1 55 59 PF00017 0.693
LIG_SH2_STAT3 593 596 PF00017 0.662
LIG_SH2_STAT5 555 558 PF00017 0.618
LIG_SH2_STAT5 713 716 PF00017 0.671
LIG_SH3_3 17 23 PF00018 0.744
LIG_SH3_3 219 225 PF00018 0.848
LIG_SH3_3 376 382 PF00018 0.773
LIG_SH3_3 459 465 PF00018 0.778
LIG_SH3_3 514 520 PF00018 0.570
LIG_SH3_3 536 542 PF00018 0.669
LIG_SUMO_SIM_anti_2 731 736 PF11976 0.630
LIG_SUMO_SIM_par_1 257 264 PF11976 0.826
LIG_SUMO_SIM_par_1 28 36 PF11976 0.463
LIG_TRAF2_1 501 504 PF00917 0.675
LIG_TYR_ITIM 714 719 PF00017 0.646
LIG_UBA3_1 58 67 PF00899 0.667
LIG_WRC_WIRS_1 606 611 PF05994 0.642
LIG_WRC_WIRS_1 697 702 PF05994 0.699
MOD_CDC14_SPxK_1 627 630 PF00782 0.716
MOD_CDK_SPK_2 147 152 PF00069 0.721
MOD_CDK_SPxK_1 624 630 PF00069 0.718
MOD_CDK_SPxxK_3 461 468 PF00069 0.788
MOD_CK1_1 143 149 PF00069 0.813
MOD_CK1_1 16 22 PF00069 0.682
MOD_CK1_1 165 171 PF00069 0.784
MOD_CK1_1 183 189 PF00069 0.574
MOD_CK1_1 194 200 PF00069 0.761
MOD_CK1_1 232 238 PF00069 0.712
MOD_CK1_1 257 263 PF00069 0.628
MOD_CK1_1 336 342 PF00069 0.752
MOD_CK1_1 356 362 PF00069 0.525
MOD_CK1_1 378 384 PF00069 0.840
MOD_CK1_1 481 487 PF00069 0.539
MOD_CK1_1 575 581 PF00069 0.647
MOD_CK2_1 300 306 PF00069 0.770
MOD_CK2_1 344 350 PF00069 0.681
MOD_CK2_1 444 450 PF00069 0.744
MOD_CK2_1 498 504 PF00069 0.671
MOD_CK2_1 507 513 PF00069 0.549
MOD_GlcNHglycan 118 121 PF01048 0.722
MOD_GlcNHglycan 123 126 PF01048 0.669
MOD_GlcNHglycan 142 145 PF01048 0.587
MOD_GlcNHglycan 185 188 PF01048 0.779
MOD_GlcNHglycan 199 202 PF01048 0.596
MOD_GlcNHglycan 257 260 PF01048 0.797
MOD_GlcNHglycan 344 347 PF01048 0.749
MOD_GlcNHglycan 669 672 PF01048 0.711
MOD_GlcNHglycan 689 692 PF01048 0.557
MOD_GlcNHglycan 701 704 PF01048 0.515
MOD_GlcNHglycan 743 746 PF01048 0.719
MOD_GSK3_1 121 128 PF00069 0.548
MOD_GSK3_1 140 147 PF00069 0.661
MOD_GSK3_1 165 172 PF00069 0.773
MOD_GSK3_1 176 183 PF00069 0.662
MOD_GSK3_1 191 198 PF00069 0.660
MOD_GSK3_1 212 219 PF00069 0.816
MOD_GSK3_1 225 232 PF00069 0.664
MOD_GSK3_1 331 338 PF00069 0.852
MOD_GSK3_1 344 351 PF00069 0.642
MOD_GSK3_1 374 381 PF00069 0.815
MOD_GSK3_1 477 484 PF00069 0.712
MOD_GSK3_1 662 669 PF00069 0.713
MOD_GSK3_1 687 694 PF00069 0.737
MOD_GSK3_1 695 702 PF00069 0.628
MOD_N-GLC_1 140 145 PF02516 0.674
MOD_NEK2_1 191 196 PF00069 0.748
MOD_NEK2_1 229 234 PF00069 0.746
MOD_NEK2_1 254 259 PF00069 0.654
MOD_NEK2_1 478 483 PF00069 0.484
MOD_NEK2_1 605 610 PF00069 0.640
MOD_NEK2_1 62 67 PF00069 0.652
MOD_NEK2_1 676 681 PF00069 0.649
MOD_NEK2_1 686 691 PF00069 0.701
MOD_NEK2_1 696 701 PF00069 0.602
MOD_PIKK_1 162 168 PF00454 0.746
MOD_PIKK_1 205 211 PF00454 0.729
MOD_PIKK_1 369 375 PF00454 0.772
MOD_PIKK_1 48 54 PF00454 0.635
MOD_PKA_1 121 127 PF00069 0.541
MOD_PKA_2 121 127 PF00069 0.648
MOD_PKA_2 176 182 PF00069 0.804
MOD_PKA_2 192 198 PF00069 0.544
MOD_PKA_2 248 254 PF00069 0.716
MOD_PKA_2 450 456 PF00069 0.764
MOD_PKA_2 667 673 PF00069 0.767
MOD_PKB_1 728 736 PF00069 0.596
MOD_Plk_1 125 131 PF00069 0.565
MOD_Plk_1 191 197 PF00069 0.773
MOD_Plk_1 420 426 PF00069 0.686
MOD_Plk_1 630 636 PF00069 0.804
MOD_Plk_1 730 736 PF00069 0.631
MOD_Plk_2-3 45 51 PF00069 0.706
MOD_Plk_4 125 131 PF00069 0.565
MOD_Plk_4 199 205 PF00069 0.828
MOD_Plk_4 257 263 PF00069 0.842
MOD_Plk_4 26 32 PF00069 0.615
MOD_Plk_4 730 736 PF00069 0.631
MOD_ProDKin_1 147 153 PF00069 0.807
MOD_ProDKin_1 165 171 PF00069 0.593
MOD_ProDKin_1 180 186 PF00069 0.624
MOD_ProDKin_1 230 236 PF00069 0.775
MOD_ProDKin_1 333 339 PF00069 0.856
MOD_ProDKin_1 378 384 PF00069 0.785
MOD_ProDKin_1 461 467 PF00069 0.655
MOD_ProDKin_1 624 630 PF00069 0.718
MOD_ProDKin_1 691 697 PF00069 0.733
MOD_SUMO_for_1 130 133 PF00179 0.720
MOD_SUMO_for_1 151 154 PF00179 0.751
TRG_DiLeu_BaEn_4 503 509 PF01217 0.674
TRG_DiLeu_BaLyEn_6 527 532 PF01217 0.704
TRG_ENDOCYTIC_2 487 490 PF00928 0.685
TRG_ENDOCYTIC_2 55 58 PF00928 0.694
TRG_ENDOCYTIC_2 716 719 PF00928 0.639
TRG_ER_diArg_1 248 250 PF00400 0.674
TRG_ER_diArg_1 323 325 PF00400 0.807
TRG_ER_diArg_1 508 511 PF00400 0.742
TRG_ER_diArg_1 546 549 PF00400 0.616
TRG_NES_CRM1_1 600 613 PF08389 0.722
TRG_NES_CRM1_1 712 726 PF08389 0.594
TRG_Pf-PMV_PEXEL_1 409 413 PF00026 0.569

Homologs

Protein Taxonomy Sequence identity Coverage
A4HA87 Leishmania braziliensis 67% 100%
A4HYG4 Leishmania infantum 100% 100%
E9AS91 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 99%
Q4QD73 Leishmania major 88% 99%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS