LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IBH0_LEIDO
TriTrypDb:
LdBPK_191400.1 * , LdCL_190018200 , LDHU3_19.1580
Length:
122

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 16
NetGPI no yes: 0, no: 16
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3Q8IBH0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBH0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.529
CLV_PCSK_KEX2_1 4 6 PF00082 0.529
CLV_PCSK_SKI1_1 4 8 PF00082 0.521
DEG_Nend_Nbox_1 1 3 PF02207 0.563
DOC_PP4_FxxP_1 106 109 PF00568 0.573
DOC_USP7_MATH_1 93 97 PF00917 0.464
DOC_WW_Pin1_4 105 110 PF00397 0.647
LIG_14-3-3_CanoR_1 44 49 PF00244 0.547
LIG_14-3-3_CanoR_1 5 11 PF00244 0.532
LIG_14-3-3_CanoR_1 59 65 PF00244 0.659
LIG_DLG_GKlike_1 44 52 PF00625 0.369
LIG_MYND_1 33 37 PF01753 0.542
MOD_CK1_1 108 114 PF00069 0.630
MOD_CK1_1 47 53 PF00069 0.594
MOD_CK1_1 60 66 PF00069 0.609
MOD_Cter_Amidation 2 5 PF01082 0.566
MOD_GlcNHglycan 49 52 PF01048 0.534
MOD_GlcNHglycan 60 63 PF01048 0.595
MOD_GlcNHglycan 78 81 PF01048 0.651
MOD_GlcNHglycan 8 11 PF01048 0.500
MOD_GlcNHglycan 95 98 PF01048 0.491
MOD_GSK3_1 104 111 PF00069 0.668
MOD_GSK3_1 43 50 PF00069 0.599
MOD_GSK3_1 53 60 PF00069 0.481
MOD_NEK2_1 104 109 PF00069 0.677
MOD_NEK2_1 57 62 PF00069 0.620
MOD_PKA_2 43 49 PF00069 0.653
MOD_PKA_2 58 64 PF00069 0.552
MOD_ProDKin_1 105 111 PF00069 0.647
MOD_SUMO_rev_2 68 78 PF00179 0.662
TRG_DiLeu_BaEn_1 73 78 PF01217 0.712
TRG_ER_diArg_1 4 6 PF00400 0.529

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3I1 Leptomonas seymouri 54% 100%
A0A0N0P7U0 Leptomonas seymouri 79% 99%
A0A0S4KKW4 Bodo saltans 39% 100%
A0A1X0P697 Trypanosomatidae 43% 98%
A0A3S7WVJ6 Leishmania donovani 53% 74%
A4HYG5 Leishmania infantum 53% 74%
D0A0T3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 100%
E9AHU8 Leishmania infantum 99% 100%
E9AI62 Leishmania braziliensis 78% 100%
E9AS83 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
E9ASA3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
Q4QD59 Leishmania major 38% 100%
Q4QD74 Leishmania major 53% 100%
Q4QD83 Leishmania major 96% 100%
V5D1C6 Trypanosoma cruzi 49% 90%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS