LeishMANIAdb
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RRM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
RRM domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8IBB5_LEIDO
TriTrypDb:
LdBPK_111040.1 , LdCL_110016200 , LDHU3_11.1270
Length:
814

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBB5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBB5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 380 384 PF00656 0.726
CLV_C14_Caspase3-7 512 516 PF00656 0.681
CLV_C14_Caspase3-7 518 522 PF00656 0.700
CLV_NRD_NRD_1 306 308 PF00675 0.572
CLV_NRD_NRD_1 459 461 PF00675 0.711
CLV_NRD_NRD_1 792 794 PF00675 0.569
CLV_PCSK_KEX2_1 306 308 PF00082 0.512
CLV_PCSK_KEX2_1 459 461 PF00082 0.711
CLV_PCSK_SKI1_1 218 222 PF00082 0.527
CLV_PCSK_SKI1_1 225 229 PF00082 0.475
CLV_PCSK_SKI1_1 563 567 PF00082 0.571
CLV_PCSK_SKI1_1 601 605 PF00082 0.723
CLV_PCSK_SKI1_1 738 742 PF00082 0.553
CLV_PCSK_SKI1_1 764 768 PF00082 0.591
CLV_PCSK_SKI1_1 797 801 PF00082 0.568
CLV_PCSK_SKI1_1 96 100 PF00082 0.735
DEG_SPOP_SBC_1 10 14 PF00917 0.699
DEG_SPOP_SBC_1 134 138 PF00917 0.699
DEG_SPOP_SBC_1 234 238 PF00917 0.622
DEG_SPOP_SBC_1 493 497 PF00917 0.700
DEG_SPOP_SBC_1 584 588 PF00917 0.704
DEG_SPOP_SBC_1 619 623 PF00917 0.721
DOC_CKS1_1 319 324 PF01111 0.583
DOC_CKS1_1 447 452 PF01111 0.638
DOC_CKS1_1 631 636 PF01111 0.750
DOC_CKS1_1 640 645 PF01111 0.724
DOC_MAPK_gen_1 199 208 PF00069 0.581
DOC_MAPK_gen_1 793 801 PF00069 0.576
DOC_PP1_RVXF_1 202 209 PF00149 0.563
DOC_PP1_RVXF_1 785 792 PF00149 0.557
DOC_PP2B_LxvP_1 53 56 PF13499 0.625
DOC_PP2B_LxvP_1 645 648 PF13499 0.644
DOC_PP2B_LxvP_1 701 704 PF13499 0.671
DOC_PP2B_LxvP_1 767 770 PF13499 0.624
DOC_PP4_FxxP_1 239 242 PF00568 0.663
DOC_PP4_FxxP_1 32 35 PF00568 0.567
DOC_PP4_FxxP_1 573 576 PF00568 0.667
DOC_PP4_FxxP_1 766 769 PF00568 0.610
DOC_USP7_MATH_1 134 138 PF00917 0.699
DOC_USP7_MATH_1 153 157 PF00917 0.523
DOC_USP7_MATH_1 244 248 PF00917 0.809
DOC_USP7_MATH_1 278 282 PF00917 0.644
DOC_USP7_MATH_1 334 338 PF00917 0.764
DOC_USP7_MATH_1 511 515 PF00917 0.674
DOC_USP7_MATH_1 559 563 PF00917 0.651
DOC_USP7_MATH_1 697 701 PF00917 0.677
DOC_USP7_MATH_1 80 84 PF00917 0.764
DOC_USP7_MATH_1 92 96 PF00917 0.582
DOC_WW_Pin1_4 154 159 PF00397 0.716
DOC_WW_Pin1_4 274 279 PF00397 0.766
DOC_WW_Pin1_4 281 286 PF00397 0.525
DOC_WW_Pin1_4 31 36 PF00397 0.667
DOC_WW_Pin1_4 318 323 PF00397 0.578
DOC_WW_Pin1_4 339 344 PF00397 0.697
DOC_WW_Pin1_4 346 351 PF00397 0.647
DOC_WW_Pin1_4 405 410 PF00397 0.721
DOC_WW_Pin1_4 415 420 PF00397 0.625
DOC_WW_Pin1_4 446 451 PF00397 0.741
DOC_WW_Pin1_4 45 50 PF00397 0.576
DOC_WW_Pin1_4 452 457 PF00397 0.720
DOC_WW_Pin1_4 630 635 PF00397 0.745
DOC_WW_Pin1_4 639 644 PF00397 0.721
DOC_WW_Pin1_4 674 679 PF00397 0.755
DOC_WW_Pin1_4 680 685 PF00397 0.684
DOC_WW_Pin1_4 729 734 PF00397 0.726
DOC_WW_Pin1_4 81 86 PF00397 0.647
LIG_14-3-3_CanoR_1 113 117 PF00244 0.654
LIG_14-3-3_CanoR_1 148 154 PF00244 0.749
LIG_14-3-3_CanoR_1 197 206 PF00244 0.591
LIG_14-3-3_CanoR_1 306 311 PF00244 0.481
LIG_14-3-3_CanoR_1 393 399 PF00244 0.610
LIG_14-3-3_CanoR_1 460 470 PF00244 0.770
LIG_14-3-3_CanoR_1 545 550 PF00244 0.622
LIG_14-3-3_CanoR_1 553 558 PF00244 0.566
LIG_14-3-3_CanoR_1 636 645 PF00244 0.690
LIG_14-3-3_CanoR_1 742 748 PF00244 0.561
LIG_14-3-3_CanoR_1 87 93 PF00244 0.629
LIG_BIR_II_1 1 5 PF00653 0.650
LIG_BIR_III_4 574 578 PF00653 0.632
LIG_BIR_III_4 63 67 PF00653 0.755
LIG_BRCT_BRCA1_1 270 274 PF00533 0.774
LIG_BRCT_BRCA1_1 32 36 PF00533 0.747
LIG_BRCT_BRCA1_1 753 757 PF00533 0.547
LIG_CSL_BTD_1 411 414 PF09270 0.719
LIG_deltaCOP1_diTrp_1 118 125 PF00928 0.683
LIG_FHA_1 106 112 PF00498 0.727
LIG_FHA_1 166 172 PF00498 0.513
LIG_FHA_1 292 298 PF00498 0.642
LIG_FHA_1 4 10 PF00498 0.607
LIG_FHA_1 456 462 PF00498 0.705
LIG_FHA_1 562 568 PF00498 0.580
LIG_FHA_1 603 609 PF00498 0.716
LIG_FHA_1 633 639 PF00498 0.734
LIG_FHA_1 640 646 PF00498 0.667
LIG_FHA_1 654 660 PF00498 0.507
LIG_FHA_1 681 687 PF00498 0.800
LIG_FHA_2 282 288 PF00498 0.454
LIG_LIR_Apic_2 122 128 PF02991 0.689
LIG_LIR_Apic_2 236 242 PF02991 0.625
LIG_LIR_Apic_2 30 35 PF02991 0.565
LIG_LIR_Apic_2 765 769 PF02991 0.600
LIG_LIR_Gen_1 136 147 PF02991 0.705
LIG_LIR_Gen_1 383 392 PF02991 0.718
LIG_LIR_Gen_1 564 573 PF02991 0.594
LIG_LIR_Gen_1 695 705 PF02991 0.609
LIG_LIR_Nem_3 136 142 PF02991 0.774
LIG_LIR_Nem_3 287 291 PF02991 0.597
LIG_LIR_Nem_3 33 39 PF02991 0.751
LIG_LIR_Nem_3 383 388 PF02991 0.644
LIG_LIR_Nem_3 564 569 PF02991 0.561
LIG_LIR_Nem_3 695 701 PF02991 0.618
LIG_LIR_Nem_3 737 743 PF02991 0.614
LIG_LIR_Nem_3 754 760 PF02991 0.328
LIG_Pex14_2 32 36 PF04695 0.572
LIG_Pex14_2 502 506 PF04695 0.625
LIG_Pex14_2 753 757 PF04695 0.547
LIG_PTAP_UEV_1 466 471 PF05743 0.614
LIG_PTB_Apo_2 440 447 PF02174 0.671
LIG_REV1ctd_RIR_1 738 746 PF16727 0.595
LIG_SH2_CRK 211 215 PF00017 0.552
LIG_SH2_CRK 385 389 PF00017 0.645
LIG_SH2_CRK 698 702 PF00017 0.682
LIG_SH2_NCK_1 120 124 PF00017 0.684
LIG_SH2_NCK_1 211 215 PF00017 0.552
LIG_SH2_NCK_1 385 389 PF00017 0.645
LIG_SH2_PTP2 187 190 PF00017 0.473
LIG_SH2_SRC 187 190 PF00017 0.473
LIG_SH2_STAP1 120 124 PF00017 0.684
LIG_SH2_STAP1 211 215 PF00017 0.552
LIG_SH2_STAP1 288 292 PF00017 0.616
LIG_SH2_STAP1 625 629 PF00017 0.739
LIG_SH2_STAT3 578 581 PF00017 0.669
LIG_SH2_STAT5 187 190 PF00017 0.505
LIG_SH2_STAT5 291 294 PF00017 0.637
LIG_SH2_STAT5 578 581 PF00017 0.733
LIG_SH2_STAT5 752 755 PF00017 0.541
LIG_SH3_1 524 530 PF00018 0.710
LIG_SH3_2 531 536 PF14604 0.606
LIG_SH3_2 558 563 PF14604 0.685
LIG_SH3_2 631 636 PF14604 0.618
LIG_SH3_3 155 161 PF00018 0.722
LIG_SH3_3 183 189 PF00018 0.545
LIG_SH3_3 272 278 PF00018 0.728
LIG_SH3_3 319 325 PF00018 0.535
LIG_SH3_3 344 350 PF00018 0.723
LIG_SH3_3 354 360 PF00018 0.621
LIG_SH3_3 385 391 PF00018 0.649
LIG_SH3_3 399 405 PF00018 0.687
LIG_SH3_3 416 422 PF00018 0.699
LIG_SH3_3 441 447 PF00018 0.640
LIG_SH3_3 464 470 PF00018 0.702
LIG_SH3_3 497 503 PF00018 0.698
LIG_SH3_3 524 530 PF00018 0.771
LIG_SH3_3 555 561 PF00018 0.740
LIG_SH3_3 603 609 PF00018 0.701
LIG_SH3_3 613 619 PF00018 0.653
LIG_SH3_3 628 634 PF00018 0.628
LIG_SUMO_SIM_par_1 106 112 PF11976 0.682
LIG_SUMO_SIM_par_1 226 232 PF11976 0.492
LIG_UBA3_1 227 231 PF00899 0.482
LIG_WW_1 769 772 PF00397 0.630
LIG_WW_2 558 561 PF00397 0.715
MOD_CDK_SPxK_1 630 636 PF00069 0.664
MOD_CDK_SPxK_1 81 87 PF00069 0.626
MOD_CDK_SPxxK_3 452 459 PF00069 0.705
MOD_CDK_SPxxK_3 680 687 PF00069 0.798
MOD_CK1_1 104 110 PF00069 0.663
MOD_CK1_1 129 135 PF00069 0.742
MOD_CK1_1 137 143 PF00069 0.665
MOD_CK1_1 157 163 PF00069 0.530
MOD_CK1_1 281 287 PF00069 0.491
MOD_CK1_1 318 324 PF00069 0.700
MOD_CK1_1 338 344 PF00069 0.547
MOD_CK1_1 386 392 PF00069 0.715
MOD_CK1_1 445 451 PF00069 0.714
MOD_CK1_1 45 51 PF00069 0.775
MOD_CK1_1 455 461 PF00069 0.701
MOD_CK1_1 465 471 PF00069 0.563
MOD_CK1_1 58 64 PF00069 0.610
MOD_CK1_1 587 593 PF00069 0.730
MOD_CK1_1 639 645 PF00069 0.766
MOD_CK1_1 674 680 PF00069 0.718
MOD_CK1_1 707 713 PF00069 0.752
MOD_CK1_1 729 735 PF00069 0.653
MOD_CK1_1 78 84 PF00069 0.497
MOD_CK2_1 274 280 PF00069 0.763
MOD_CK2_1 281 287 PF00069 0.520
MOD_GlcNHglycan 246 249 PF01048 0.810
MOD_GlcNHglycan 261 265 PF01048 0.589
MOD_GlcNHglycan 464 467 PF01048 0.705
MOD_GlcNHglycan 593 596 PF01048 0.765
MOD_GlcNHglycan 60 63 PF01048 0.787
MOD_GlcNHglycan 650 653 PF01048 0.767
MOD_GlcNHglycan 660 663 PF01048 0.567
MOD_GlcNHglycan 80 83 PF01048 0.539
MOD_GlcNHglycan 88 91 PF01048 0.733
MOD_GSK3_1 129 136 PF00069 0.746
MOD_GSK3_1 153 160 PF00069 0.728
MOD_GSK3_1 161 168 PF00069 0.502
MOD_GSK3_1 244 251 PF00069 0.821
MOD_GSK3_1 27 34 PF00069 0.534
MOD_GSK3_1 274 281 PF00069 0.636
MOD_GSK3_1 334 341 PF00069 0.761
MOD_GSK3_1 342 349 PF00069 0.639
MOD_GSK3_1 38 45 PF00069 0.616
MOD_GSK3_1 442 449 PF00069 0.665
MOD_GSK3_1 461 468 PF00069 0.645
MOD_GSK3_1 583 590 PF00069 0.777
MOD_GSK3_1 608 615 PF00069 0.782
MOD_GSK3_1 632 639 PF00069 0.760
MOD_GSK3_1 672 679 PF00069 0.761
MOD_GSK3_1 692 699 PF00069 0.546
MOD_GSK3_1 703 710 PF00069 0.594
MOD_GSK3_1 9 16 PF00069 0.734
MOD_GSK3_1 97 104 PF00069 0.724
MOD_LATS_1 551 557 PF00433 0.615
MOD_LATS_1 599 605 PF00433 0.693
MOD_N-GLC_1 808 813 PF02516 0.661
MOD_NEK2_1 105 110 PF00069 0.709
MOD_NEK2_1 3 8 PF00069 0.677
MOD_NEK2_1 658 663 PF00069 0.596
MOD_NEK2_1 743 748 PF00069 0.526
MOD_NEK2_1 9 14 PF00069 0.689
MOD_NEK2_2 561 566 PF00069 0.599
MOD_PIKK_1 291 297 PF00454 0.586
MOD_PIKK_1 38 44 PF00454 0.711
MOD_PIKK_1 383 389 PF00454 0.723
MOD_PIKK_1 636 642 PF00454 0.720
MOD_PIKK_1 692 698 PF00454 0.745
MOD_PIKK_1 704 710 PF00454 0.661
MOD_PKA_1 306 312 PF00069 0.487
MOD_PKA_2 112 118 PF00069 0.734
MOD_PKA_2 147 153 PF00069 0.651
MOD_PKA_2 248 254 PF00069 0.695
MOD_PKA_2 27 33 PF00069 0.625
MOD_PKA_2 306 312 PF00069 0.423
MOD_PKA_2 552 558 PF00069 0.607
MOD_PKA_2 58 64 PF00069 0.786
MOD_PKA_2 584 590 PF00069 0.772
MOD_PKA_2 692 698 PF00069 0.618
MOD_PKA_2 86 92 PF00069 0.629
MOD_Plk_1 72 78 PF00069 0.619
MOD_Plk_1 808 814 PF00069 0.677
MOD_Plk_2-3 112 118 PF00069 0.734
MOD_Plk_4 165 171 PF00069 0.561
MOD_Plk_4 219 225 PF00069 0.569
MOD_Plk_4 27 33 PF00069 0.695
MOD_Plk_4 300 306 PF00069 0.608
MOD_Plk_4 743 749 PF00069 0.554
MOD_ProDKin_1 154 160 PF00069 0.710
MOD_ProDKin_1 274 280 PF00069 0.763
MOD_ProDKin_1 281 287 PF00069 0.520
MOD_ProDKin_1 31 37 PF00069 0.670
MOD_ProDKin_1 318 324 PF00069 0.579
MOD_ProDKin_1 339 345 PF00069 0.699
MOD_ProDKin_1 346 352 PF00069 0.649
MOD_ProDKin_1 405 411 PF00069 0.725
MOD_ProDKin_1 415 421 PF00069 0.626
MOD_ProDKin_1 446 452 PF00069 0.742
MOD_ProDKin_1 45 51 PF00069 0.580
MOD_ProDKin_1 630 636 PF00069 0.749
MOD_ProDKin_1 639 645 PF00069 0.723
MOD_ProDKin_1 674 680 PF00069 0.755
MOD_ProDKin_1 685 691 PF00069 0.614
MOD_ProDKin_1 729 735 PF00069 0.716
MOD_ProDKin_1 81 87 PF00069 0.650
TRG_AP2beta_CARGO_1 755 764 PF09066 0.560
TRG_DiLeu_BaLyEn_6 565 570 PF01217 0.573
TRG_DiLeu_BaLyEn_6 654 659 PF01217 0.678
TRG_ENDOCYTIC_2 211 214 PF00928 0.547
TRG_ENDOCYTIC_2 385 388 PF00928 0.724
TRG_ENDOCYTIC_2 698 701 PF00928 0.683
TRG_ENDOCYTIC_2 763 766 PF00928 0.580
TRG_ER_diArg_1 305 307 PF00400 0.510
TRG_ER_diArg_1 459 461 PF00400 0.711
TRG_ER_diArg_1 56 59 PF00400 0.779
TRG_ER_diArg_1 93 96 PF00400 0.711
TRG_NES_CRM1_1 219 232 PF08389 0.480

Homologs

Protein Taxonomy Sequence identity Coverage
A4H6N0 Leishmania braziliensis 65% 100%
A4HV13 Leishmania infantum 99% 100%
E9ANP8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4QGX5 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS