SUZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IBA4_LEIDO

TriTrypDb:

LdBPK_240800.1 , LdCL_240013000 , LDHU3_24.0930

Length:

310

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IBA4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IBA4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	285	289	PF00656	0.691
CLV_C14_Caspase3-7	60	64	PF00656	0.643
CLV_NRD_NRD_1	144	146	PF00675	0.765
CLV_NRD_NRD_1	171	173	PF00675	0.632
CLV_NRD_NRD_1	192	194	PF00675	0.536
CLV_NRD_NRD_1	301	303	PF00675	0.592
CLV_NRD_NRD_1	37	39	PF00675	0.648
CLV_PCSK_FUR_1	190	194	PF00082	0.532
CLV_PCSK_KEX2_1	144	146	PF00082	0.767
CLV_PCSK_KEX2_1	171	173	PF00082	0.632
CLV_PCSK_KEX2_1	192	194	PF00082	0.536
CLV_PCSK_KEX2_1	301	303	PF00082	0.592
CLV_PCSK_KEX2_1	36	38	PF00082	0.635
CLV_PCSK_PC1ET2_1	36	38	PF00082	0.635
CLV_PCSK_PC7_1	140	146	PF00082	0.710
CLV_PCSK_SKI1_1	145	149	PF00082	0.617
CLV_PCSK_SKI1_1	199	203	PF00082	0.565
CLV_PCSK_SKI1_1	84	88	PF00082	0.523
CLV_PCSK_SKI1_1	89	93	PF00082	0.531
DEG_APCC_DBOX_1	198	206	PF00400	0.558
DEG_SCF_TRCP1_1	63	69	PF00400	0.606
DEG_SPOP_SBC_1	130	134	PF00917	0.640
DOC_ANK_TNKS_1	152	159	PF00023	0.785
DOC_CYCLIN_RxL_1	84	94	PF00134	0.584
DOC_MAPK_gen_1	187	197	PF00069	0.530
DOC_MAPK_MEF2A_6	97	104	PF00069	0.643
DOC_PP4_FxxP_1	109	112	PF00568	0.736
DOC_PP4_FxxP_1	231	234	PF00568	0.770
DOC_USP7_MATH_1	126	130	PF00917	0.650
DOC_USP7_MATH_1	13	17	PF00917	0.774
DOC_USP7_MATH_1	178	182	PF00917	0.703
DOC_USP7_MATH_1	40	44	PF00917	0.735
DOC_USP7_MATH_1	53	57	PF00917	0.593
DOC_USP7_MATH_1	66	70	PF00917	0.590
DOC_WW_Pin1_4	131	136	PF00397	0.822
DOC_WW_Pin1_4	271	276	PF00397	0.811
DOC_WW_Pin1_4	304	309	PF00397	0.643
DOC_WW_Pin1_4	96	101	PF00397	0.550
LIG_14-3-3_CanoR_1	251	257	PF00244	0.790
LIG_14-3-3_CanoR_1	268	274	PF00244	0.531
LIG_14-3-3_CanoR_1	301	305	PF00244	0.593
LIG_14-3-3_CanoR_1	38	46	PF00244	0.625
LIG_ActinCP_TwfCPI_2	231	240	PF01115	0.705
LIG_BIR_II_1	1	5	PF00653	0.586
LIG_BIR_III_4	246	250	PF00653	0.717
LIG_BRCT_BRCA1_1	302	306	PF00533	0.773
LIG_FHA_1	97	103	PF00498	0.559
LIG_FHA_2	283	289	PF00498	0.687
LIG_FHA_2	76	82	PF00498	0.552
LIG_Integrin_RGD_1	286	288	PF01839	0.709
LIG_LIR_Apic_2	107	112	PF02991	0.731
LIG_LIR_Apic_2	229	234	PF02991	0.766
LIG_LIR_Gen_1	209	219	PF02991	0.606
LIG_LIR_Nem_3	209	215	PF02991	0.596
LIG_LIR_Nem_3	271	276	PF02991	0.689
LIG_LIR_Nem_3	303	309	PF02991	0.628
LIG_PCNA_yPIPBox_3	82	92	PF02747	0.542
LIG_SH2_CRK	173	177	PF00017	0.730
LIG_SH2_CRK	212	216	PF00017	0.746
LIG_SH2_NCK_1	117	121	PF00017	0.717
LIG_SH2_STAT5	117	120	PF00017	0.788
LIG_SH2_STAT5	235	238	PF00017	0.708
LIG_SH3_1	302	308	PF00018	0.603
LIG_SH3_3	302	308	PF00018	0.636
LIG_TRAF2_1	16	19	PF00917	0.771
LIG_TRAF2_1	181	184	PF00917	0.564
LIG_TYR_ITIM	210	215	PF00017	0.600
MOD_CK1_1	129	135	PF00069	0.671
MOD_CK1_1	252	258	PF00069	0.795
MOD_CK1_1	271	277	PF00069	0.592
MOD_CK1_1	56	62	PF00069	0.700
MOD_CK1_1	64	70	PF00069	0.621
MOD_CK2_1	13	19	PF00069	0.637
MOD_CK2_1	178	184	PF00069	0.564
MOD_CK2_1	75	81	PF00069	0.566
MOD_Cter_Amidation	299	302	PF01082	0.595
MOD_GlcNHglycan	128	131	PF01048	0.692
MOD_GlcNHglycan	163	167	PF01048	0.591
MOD_GlcNHglycan	295	298	PF01048	0.683
MOD_GlcNHglycan	302	305	PF01048	0.734
MOD_GlcNHglycan	6	9	PF01048	0.762
MOD_GlcNHglycan	63	66	PF01048	0.671
MOD_GSK3_1	125	132	PF00069	0.693
MOD_GSK3_1	300	307	PF00069	0.789
MOD_GSK3_1	53	60	PF00069	0.809
MOD_N-GLC_1	178	183	PF02516	0.566
MOD_NEK2_1	213	218	PF00069	0.763
MOD_NEK2_1	27	32	PF00069	0.613
MOD_PIKK_1	213	219	PF00454	0.614
MOD_PKA_2	13	19	PF00069	0.637
MOD_PKA_2	227	233	PF00069	0.568
MOD_PKA_2	279	285	PF00069	0.707
MOD_PKA_2	300	306	PF00069	0.595
MOD_PKB_1	266	274	PF00069	0.696
MOD_Plk_1	27	33	PF00069	0.611
MOD_Plk_2-3	206	212	PF00069	0.588
MOD_Plk_4	27	33	PF00069	0.747
MOD_Plk_4	75	81	PF00069	0.569
MOD_ProDKin_1	131	137	PF00069	0.821
MOD_ProDKin_1	271	277	PF00069	0.813
MOD_ProDKin_1	304	310	PF00069	0.627
MOD_ProDKin_1	96	102	PF00069	0.550
TRG_DiLeu_BaEn_3	183	189	PF01217	0.488
TRG_ENDOCYTIC_2	212	215	PF00928	0.606
TRG_ER_diArg_1	150	153	PF00400	0.656
TRG_ER_diArg_1	170	172	PF00400	0.752
TRG_ER_diArg_1	189	192	PF00400	0.389
TRG_ER_diArg_1	256	259	PF00400	0.701
TRG_ER_diArg_1	265	268	PF00400	0.612
TRG_NLS_MonoExtC_3	35	40	PF00514	0.563
TRG_NLS_MonoExtN_4	33	40	PF00514	0.558
TRG_Pf-PMV_PEXEL_1	89	94	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5G1	Leptomonas seymouri	42%	100%
A4HDD6	Leishmania braziliensis	68%	98%
A4I0R7	Leishmania infantum	98%	100%
E9AWR9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	95%
Q4QAQ5	Leishmania major	85%	99%