Chromosome partition protein Smc

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IB89_LEIDO

TriTrypDb:

LdBPK_190720.1 , LdCL_190012200 , LDHU3_19.0800

Length:

304

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IB89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IB89

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	129	133	PF00656	0.601
CLV_C14_Caspase3-7	255	259	PF00656	0.570
CLV_NRD_NRD_1	151	153	PF00675	0.501
CLV_NRD_NRD_1	291	293	PF00675	0.594
CLV_PCSK_SKI1_1	125	129	PF00082	0.634
CLV_PCSK_SKI1_1	197	201	PF00082	0.486
CLV_PCSK_SKI1_1	247	251	PF00082	0.618
DEG_APCC_DBOX_1	196	204	PF00400	0.545
DEG_APCC_DBOX_1	246	254	PF00400	0.540
DEG_Nend_UBRbox_2	1	3	PF02207	0.602
DEG_SPOP_SBC_1	297	301	PF00917	0.763
DOC_USP7_MATH_1	252	256	PF00917	0.577
DOC_USP7_UBL2_3	153	157	PF12436	0.580
DOC_WW_Pin1_4	293	298	PF00397	0.689
LIG_14-3-3_CanoR_1	125	131	PF00244	0.572
LIG_14-3-3_CanoR_1	245	253	PF00244	0.612
LIG_BIR_III_4	132	136	PF00653	0.414
LIG_FHA_2	274	280	PF00498	0.611
LIG_LIR_Gen_1	272	283	PF02991	0.568
LIG_LIR_Nem_3	208	214	PF02991	0.506
LIG_LIR_Nem_3	266	271	PF02991	0.530
LIG_LIR_Nem_3	272	278	PF02991	0.540
LIG_NRP_CendR_1	303	304	PF00754	0.792
LIG_PCNA_yPIPBox_3	56	69	PF02747	0.620
LIG_RPA_C_Fungi	222	234	PF08784	0.545
LIG_TRAF2_1	176	179	PF00917	0.433
LIG_TRAF2_1	213	216	PF00917	0.484
MOD_CK1_1	204	210	PF00069	0.558
MOD_CK1_1	296	302	PF00069	0.729
MOD_CK2_1	188	194	PF00069	0.592
MOD_CK2_1	210	216	PF00069	0.489
MOD_CK2_1	273	279	PF00069	0.516
MOD_GlcNHglycan	190	193	PF01048	0.609
MOD_GlcNHglycan	215	219	PF01048	0.495
MOD_GlcNHglycan	238	242	PF01048	0.617
MOD_GSK3_1	210	217	PF00069	0.484
MOD_GSK3_1	293	300	PF00069	0.687
MOD_LATS_1	151	157	PF00433	0.471
MOD_NEK2_1	18	23	PF00069	0.532
MOD_NEK2_1	288	293	PF00069	0.644
MOD_NEK2_1	37	42	PF00069	0.601
MOD_NEK2_1	7	12	PF00069	0.554
MOD_NEK2_2	126	131	PF00069	0.494
MOD_NEK2_2	298	303	PF00069	0.746
MOD_PIKK_1	37	43	PF00454	0.550
MOD_PKA_2	151	157	PF00069	0.576
MOD_PKA_2	188	194	PF00069	0.676
MOD_Plk_1	237	243	PF00069	0.588
MOD_Plk_4	64	70	PF00069	0.647
MOD_ProDKin_1	293	299	PF00069	0.690
MOD_SUMO_rev_2	97	105	PF00179	0.534
TRG_DiLeu_BaLyEn_6	9	14	PF01217	0.663
TRG_ER_diArg_1	302	304	PF00400	0.786
TRG_ER_diArg_1	81	84	PF00400	0.595
TRG_Pf-PMV_PEXEL_1	56	60	PF00026	0.650

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIA8	Leptomonas seymouri	76%	100%
A0A1X0P7A5	Trypanosomatidae	37%	97%
A0A422NN36	Trypanosoma rangeli	35%	100%
A4HA29	Leishmania braziliensis	85%	99%
A4HY92	Leishmania infantum	99%	100%
D0A0M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
E9AS24	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4QDE9	Leishmania major	95%	100%
V5B7K2	Trypanosoma cruzi	38%	99%