Ttaggg binding factor, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ttaggg binding factor, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IB42_LEIDO

TriTrypDb:

LdBPK_181260.1 , LdCL_180017800 , LDHU3_18.1590

Length:

797

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IB42

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IB42

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	375	379	PF00656	0.732
CLV_C14_Caspase3-7	430	434	PF00656	0.829
CLV_C14_Caspase3-7	481	485	PF00656	0.819
CLV_C14_Caspase3-7	495	499	PF00656	0.600
CLV_C14_Caspase3-7	503	507	PF00656	0.637
CLV_NRD_NRD_1	168	170	PF00675	0.859
CLV_NRD_NRD_1	244	246	PF00675	0.788
CLV_NRD_NRD_1	259	261	PF00675	0.616
CLV_NRD_NRD_1	298	300	PF00675	0.795
CLV_NRD_NRD_1	321	323	PF00675	0.750
CLV_NRD_NRD_1	345	347	PF00675	0.859
CLV_NRD_NRD_1	521	523	PF00675	0.715
CLV_NRD_NRD_1	655	657	PF00675	0.815
CLV_NRD_NRD_1	684	686	PF00675	0.678
CLV_NRD_NRD_1	740	742	PF00675	0.670
CLV_NRD_NRD_1	76	78	PF00675	0.609
CLV_PCSK_FUR_1	296	300	PF00082	0.727
CLV_PCSK_KEX2_1	168	170	PF00082	0.859
CLV_PCSK_KEX2_1	259	261	PF00082	0.739
CLV_PCSK_KEX2_1	296	298	PF00082	0.736
CLV_PCSK_KEX2_1	321	323	PF00082	0.750
CLV_PCSK_KEX2_1	347	349	PF00082	0.858
CLV_PCSK_KEX2_1	521	523	PF00082	0.715
CLV_PCSK_KEX2_1	58	60	PF00082	0.446
CLV_PCSK_KEX2_1	655	657	PF00082	0.826
CLV_PCSK_KEX2_1	683	685	PF00082	0.702
CLV_PCSK_KEX2_1	739	741	PF00082	0.583
CLV_PCSK_KEX2_1	76	78	PF00082	0.543
CLV_PCSK_PC1ET2_1	347	349	PF00082	0.858
CLV_PCSK_PC1ET2_1	58	60	PF00082	0.422
CLV_PCSK_PC7_1	735	741	PF00082	0.560
CLV_PCSK_SKI1_1	52	56	PF00082	0.692
CLV_PCSK_SKI1_1	530	534	PF00082	0.794
CLV_PCSK_SKI1_1	581	585	PF00082	0.595
CLV_PCSK_SKI1_1	725	729	PF00082	0.570
CLV_PCSK_SKI1_1	735	739	PF00082	0.489
CLV_PCSK_SKI1_1	756	760	PF00082	0.652
DEG_SCF_FBW7_2	132	138	PF00400	0.660
DEG_SPOP_SBC_1	291	295	PF00917	0.690
DEG_SPOP_SBC_1	354	358	PF00917	0.818
DEG_SPOP_SBC_1	461	465	PF00917	0.727
DEG_SPOP_SBC_1	643	647	PF00917	0.725
DEG_SPOP_SBC_1	675	679	PF00917	0.827
DOC_CKS1_1	132	137	PF01111	0.742
DOC_CKS1_1	777	782	PF01111	0.808
DOC_CYCLIN_yCln2_LP_2	123	129	PF00134	0.729
DOC_CYCLIN_yCln2_LP_2	422	428	PF00134	0.742
DOC_MAPK_gen_1	722	730	PF00069	0.630
DOC_PP2B_LxvP_1	123	126	PF13499	0.806
DOC_PP2B_LxvP_1	338	341	PF13499	0.704
DOC_PP2B_LxvP_1	422	425	PF13499	0.735
DOC_PP2B_LxvP_1	641	644	PF13499	0.694
DOC_PP2B_LxvP_1	87	90	PF13499	0.588
DOC_PP2B_PxIxI_1	142	148	PF00149	0.695
DOC_USP7_MATH_1	182	186	PF00917	0.777
DOC_USP7_MATH_1	229	233	PF00917	0.700
DOC_USP7_MATH_1	264	268	PF00917	0.740
DOC_USP7_MATH_1	291	295	PF00917	0.763
DOC_USP7_MATH_1	349	353	PF00917	0.847
DOC_USP7_MATH_1	355	359	PF00917	0.779
DOC_USP7_MATH_1	360	364	PF00917	0.705
DOC_USP7_MATH_1	372	376	PF00917	0.700
DOC_USP7_MATH_1	532	536	PF00917	0.722
DOC_USP7_MATH_1	540	544	PF00917	0.645
DOC_USP7_MATH_1	570	574	PF00917	0.707
DOC_USP7_MATH_1	628	632	PF00917	0.781
DOC_USP7_MATH_1	635	639	PF00917	0.712
DOC_USP7_MATH_1	644	648	PF00917	0.575
DOC_USP7_MATH_1	716	720	PF00917	0.580
DOC_USP7_MATH_1	744	748	PF00917	0.619
DOC_WW_Pin1_4	125	130	PF00397	0.789
DOC_WW_Pin1_4	131	136	PF00397	0.754
DOC_WW_Pin1_4	138	143	PF00397	0.626
DOC_WW_Pin1_4	153	158	PF00397	0.715
DOC_WW_Pin1_4	161	166	PF00397	0.730
DOC_WW_Pin1_4	172	177	PF00397	0.599
DOC_WW_Pin1_4	178	183	PF00397	0.743
DOC_WW_Pin1_4	196	201	PF00397	0.522
DOC_WW_Pin1_4	2	7	PF00397	0.684
DOC_WW_Pin1_4	205	210	PF00397	0.668
DOC_WW_Pin1_4	238	243	PF00397	0.840
DOC_WW_Pin1_4	686	691	PF00397	0.691
DOC_WW_Pin1_4	770	775	PF00397	0.815
DOC_WW_Pin1_4	776	781	PF00397	0.712
DOC_WW_Pin1_4	9	14	PF00397	0.711
LIG_14-3-3_CanoR_1	100	105	PF00244	0.570
LIG_14-3-3_CanoR_1	18	25	PF00244	0.811
LIG_14-3-3_CanoR_1	236	242	PF00244	0.718
LIG_14-3-3_CanoR_1	348	355	PF00244	0.742
LIG_14-3-3_CanoR_1	476	480	PF00244	0.679
LIG_14-3-3_CanoR_1	52	61	PF00244	0.543
LIG_14-3-3_CanoR_1	581	589	PF00244	0.783
LIG_14-3-3_CanoR_1	605	613	PF00244	0.599
LIG_14-3-3_CanoR_1	722	731	PF00244	0.632
LIG_14-3-3_CanoR_1	76	86	PF00244	0.523
LIG_Actin_WH2_2	507	523	PF00022	0.647
LIG_BIR_III_2	484	488	PF00653	0.818
LIG_BRCT_BRCA1_1	706	710	PF00533	0.551
LIG_BRCT_BRCA1_1	94	98	PF00533	0.567
LIG_FHA_1	118	124	PF00498	0.756
LIG_FHA_1	391	397	PF00498	0.776
LIG_FHA_1	467	473	PF00498	0.779
LIG_FHA_1	589	595	PF00498	0.819
LIG_FHA_1	615	621	PF00498	0.625
LIG_FHA_1	625	631	PF00498	0.699
LIG_FHA_1	647	653	PF00498	0.737
LIG_FHA_1	677	683	PF00498	0.833
LIG_FHA_2	101	107	PF00498	0.563
LIG_FHA_2	209	215	PF00498	0.634
LIG_FHA_2	308	314	PF00498	0.544
LIG_FHA_2	616	622	PF00498	0.648
LIG_GBD_Chelix_1	109	117	PF00786	0.585
LIG_Integrin_RGD_1	43	45	PF01839	0.726
LIG_LIR_Apic_2	411	417	PF02991	0.654
LIG_LIR_Apic_2	529	534	PF02991	0.692
LIG_LIR_Gen_1	707	717	PF02991	0.555
LIG_LIR_Nem_3	60	66	PF02991	0.534
LIG_LIR_Nem_3	707	713	PF02991	0.539
LIG_NRBOX	214	220	PF00104	0.641
LIG_NRBOX	264	270	PF00104	0.776
LIG_RPA_C_Fungi	651	663	PF08784	0.620
LIG_SH2_GRB2like	414	417	PF00017	0.679
LIG_SH2_NCK_1	137	141	PF00017	0.612
LIG_SH2_PTP2	414	417	PF00017	0.679
LIG_SH2_SRC	414	417	PF00017	0.679
LIG_SH2_STAT5	315	318	PF00017	0.620
LIG_SH2_STAT5	414	417	PF00017	0.661
LIG_SH2_STAT5	63	66	PF00017	0.520
LIG_SH2_STAT5	712	715	PF00017	0.611
LIG_SH3_1	168	174	PF00018	0.808
LIG_SH3_1	771	777	PF00018	0.819
LIG_SH3_3	123	129	PF00018	0.647
LIG_SH3_3	168	174	PF00018	0.725
LIG_SH3_3	181	187	PF00018	0.745
LIG_SH3_3	236	242	PF00018	0.842
LIG_SH3_3	63	69	PF00018	0.668
LIG_SH3_3	666	672	PF00018	0.829
LIG_SH3_3	771	777	PF00018	0.819
LIG_SUMO_SIM_anti_2	515	521	PF11976	0.750
LIG_SUMO_SIM_par_1	208	214	PF11976	0.697
LIG_SUMO_SIM_par_1	68	73	PF11976	0.570
LIG_SUMO_SIM_par_1	80	88	PF11976	0.487
LIG_SxIP_EBH_1	368	377	PF03271	0.684
LIG_SxIP_EBH_1	581	594	PF03271	0.606
LIG_TRAF2_1	427	430	PF00917	0.758
LIG_TRAF2_1	689	692	PF00917	0.656
LIG_TYR_ITIM	61	66	PF00017	0.593
MOD_CDK_SPK_2	201	206	PF00069	0.743
MOD_CDK_SPxxK_3	161	168	PF00069	0.793
MOD_CDK_SPxxK_3	238	245	PF00069	0.760
MOD_CDK_SPxxK_3	776	783	PF00069	0.644
MOD_CK1_1	128	134	PF00069	0.803
MOD_CK1_1	172	178	PF00069	0.726
MOD_CK1_1	185	191	PF00069	0.725
MOD_CK1_1	199	205	PF00069	0.650
MOD_CK1_1	238	244	PF00069	0.744
MOD_CK1_1	280	286	PF00069	0.796
MOD_CK1_1	358	364	PF00069	0.813
MOD_CK1_1	37	43	PF00069	0.801
MOD_CK1_1	431	437	PF00069	0.705
MOD_CK1_1	447	453	PF00069	0.796
MOD_CK1_1	5	11	PF00069	0.775
MOD_CK1_1	573	579	PF00069	0.784
MOD_CK1_1	587	593	PF00069	0.723
MOD_CK1_1	623	629	PF00069	0.716
MOD_CK1_1	642	648	PF00069	0.744
MOD_CK1_1	677	683	PF00069	0.768
MOD_CK1_1	88	94	PF00069	0.683
MOD_CK2_1	100	106	PF00069	0.607
MOD_CK2_1	307	313	PF00069	0.544
MOD_CK2_1	615	621	PF00069	0.606
MOD_CK2_1	686	692	PF00069	0.565
MOD_CK2_1	785	791	PF00069	0.710
MOD_CK2_1	88	94	PF00069	0.595
MOD_Cter_Amidation	243	246	PF01082	0.685
MOD_GlcNHglycan	14	17	PF01048	0.687
MOD_GlcNHglycan	19	22	PF01048	0.684
MOD_GlcNHglycan	249	252	PF01048	0.723
MOD_GlcNHglycan	358	361	PF01048	0.803
MOD_GlcNHglycan	36	39	PF01048	0.710
MOD_GlcNHglycan	363	366	PF01048	0.848
MOD_GlcNHglycan	374	377	PF01048	0.663
MOD_GlcNHglycan	45	49	PF01048	0.702
MOD_GlcNHglycan	492	495	PF01048	0.736
MOD_GlcNHglycan	509	513	PF01048	0.765
MOD_GlcNHglycan	526	529	PF01048	0.590
MOD_GlcNHglycan	534	537	PF01048	0.711
MOD_GlcNHglycan	538	541	PF01048	0.728
MOD_GlcNHglycan	542	545	PF01048	0.728
MOD_GlcNHglycan	556	559	PF01048	0.546
MOD_GlcNHglycan	572	575	PF01048	0.576
MOD_GlcNHglycan	606	609	PF01048	0.608
MOD_GlcNHglycan	621	625	PF01048	0.662
MOD_GlcNHglycan	630	633	PF01048	0.673
MOD_GlcNHglycan	641	644	PF01048	0.733
MOD_GlcNHglycan	663	666	PF01048	0.810
MOD_GlcNHglycan	7	10	PF01048	0.696
MOD_GlcNHglycan	706	709	PF01048	0.651
MOD_GSK3_1	1	8	PF00069	0.728
MOD_GSK3_1	117	124	PF00069	0.749
MOD_GSK3_1	12	19	PF00069	0.714
MOD_GSK3_1	153	160	PF00069	0.843
MOD_GSK3_1	174	181	PF00069	0.737
MOD_GSK3_1	201	208	PF00069	0.725
MOD_GSK3_1	277	284	PF00069	0.791
MOD_GSK3_1	286	293	PF00069	0.624
MOD_GSK3_1	349	356	PF00069	0.812
MOD_GSK3_1	366	373	PF00069	0.591
MOD_GSK3_1	428	435	PF00069	0.709
MOD_GSK3_1	443	450	PF00069	0.809
MOD_GSK3_1	462	469	PF00069	0.496
MOD_GSK3_1	532	539	PF00069	0.682
MOD_GSK3_1	554	561	PF00069	0.705
MOD_GSK3_1	564	571	PF00069	0.814
MOD_GSK3_1	573	580	PF00069	0.615
MOD_GSK3_1	583	590	PF00069	0.685
MOD_GSK3_1	620	627	PF00069	0.766
MOD_GSK3_1	635	642	PF00069	0.560
MOD_GSK3_1	646	653	PF00069	0.601
MOD_GSK3_1	744	751	PF00069	0.709
MOD_GSK3_1	88	95	PF00069	0.678
MOD_N-GLC_1	284	289	PF02516	0.762
MOD_N-GLC_1	366	371	PF02516	0.633
MOD_N-GLC_1	450	455	PF02516	0.764
MOD_N-GLC_1	650	655	PF02516	0.743
MOD_NEK2_1	117	122	PF00069	0.632
MOD_NEK2_1	443	448	PF00069	0.741
MOD_NEK2_1	556	561	PF00069	0.715
MOD_NEK2_1	564	569	PF00069	0.802
MOD_NEK2_1	577	582	PF00069	0.659
MOD_NEK2_1	583	588	PF00069	0.695
MOD_NEK2_1	620	625	PF00069	0.758
MOD_NEK2_1	639	644	PF00069	0.766
MOD_NEK2_1	98	103	PF00069	0.568
MOD_PIKK_1	146	152	PF00454	0.638
MOD_PIKK_1	328	334	PF00454	0.657
MOD_PKA_2	17	23	PF00069	0.823
MOD_PKA_2	235	241	PF00069	0.839
MOD_PKA_2	278	284	PF00069	0.787
MOD_PKA_2	349	355	PF00069	0.739
MOD_PKA_2	475	481	PF00069	0.681
MOD_PKA_2	604	610	PF00069	0.620
MOD_PKB_1	346	354	PF00069	0.735
MOD_Plk_1	474	480	PF00069	0.680
MOD_Plk_2-3	475	481	PF00069	0.681
MOD_Plk_2-3	785	791	PF00069	0.789
MOD_Plk_4	264	270	PF00069	0.776
MOD_Plk_4	315	321	PF00069	0.655
MOD_Plk_4	438	444	PF00069	0.747
MOD_ProDKin_1	125	131	PF00069	0.790
MOD_ProDKin_1	138	144	PF00069	0.627
MOD_ProDKin_1	153	159	PF00069	0.719
MOD_ProDKin_1	161	167	PF00069	0.732
MOD_ProDKin_1	172	178	PF00069	0.594
MOD_ProDKin_1	196	202	PF00069	0.819
MOD_ProDKin_1	2	8	PF00069	0.685
MOD_ProDKin_1	205	211	PF00069	0.660
MOD_ProDKin_1	238	244	PF00069	0.840
MOD_ProDKin_1	686	692	PF00069	0.678
MOD_ProDKin_1	770	776	PF00069	0.816
MOD_ProDKin_1	9	15	PF00069	0.713
TRG_DiLeu_BaLyEn_6	49	54	PF01217	0.670
TRG_DiLeu_BaLyEn_6	551	556	PF01217	0.721
TRG_ENDOCYTIC_2	63	66	PF00928	0.520
TRG_ENDOCYTIC_2	717	720	PF00928	0.504
TRG_ER_diArg_1	296	299	PF00400	0.806
TRG_ER_diArg_1	320	322	PF00400	0.741
TRG_ER_diArg_1	346	349	PF00400	0.853
TRG_ER_diArg_1	520	522	PF00400	0.714
TRG_ER_diArg_1	682	685	PF00400	0.709
TRG_ER_diArg_1	738	741	PF00400	0.562
TRG_ER_diArg_1	75	77	PF00400	0.591
TRG_NLS_MonoCore_2	346	351	PF00514	0.858
TRG_NLS_MonoExtC_3	345	350	PF00514	0.858
TRG_NLS_MonoExtN_4	346	351	PF00514	0.854
TRG_Pf-PMV_PEXEL_1	52	56	PF00026	0.569

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWT6	Leptomonas seymouri	32%	100%
A4H9N4	Leishmania braziliensis	67%	100%
A4HXZ8	Leishmania infantum	99%	100%
E9ARR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4QDR7	Leishmania major	89%	100%