Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8IB34_LEIDO

TriTrypDb:

LdBPK_181390.1 , LdCL_180019200 , LDHU3_18.1770

Length:

953

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IB34

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IB34

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	55	59	PF00656	0.530
CLV_C14_Caspase3-7	562	566	PF00656	0.672
CLV_C14_Caspase3-7	663	667	PF00656	0.568
CLV_NRD_NRD_1	151	153	PF00675	0.695
CLV_NRD_NRD_1	27	29	PF00675	0.579
CLV_NRD_NRD_1	360	362	PF00675	0.663
CLV_NRD_NRD_1	407	409	PF00675	0.703
CLV_NRD_NRD_1	556	558	PF00675	0.638
CLV_NRD_NRD_1	618	620	PF00675	0.508
CLV_NRD_NRD_1	724	726	PF00675	0.674
CLV_PCSK_KEX2_1	407	409	PF00082	0.703
CLV_PCSK_KEX2_1	523	525	PF00082	0.596
CLV_PCSK_KEX2_1	558	560	PF00082	0.627
CLV_PCSK_KEX2_1	598	600	PF00082	0.603
CLV_PCSK_KEX2_1	618	620	PF00082	0.397
CLV_PCSK_KEX2_1	724	726	PF00082	0.674
CLV_PCSK_KEX2_1	730	732	PF00082	0.610
CLV_PCSK_KEX2_1	742	744	PF00082	0.536
CLV_PCSK_KEX2_1	950	952	PF00082	0.558
CLV_PCSK_PC1ET2_1	523	525	PF00082	0.675
CLV_PCSK_PC1ET2_1	558	560	PF00082	0.624
CLV_PCSK_PC1ET2_1	598	600	PF00082	0.603
CLV_PCSK_PC1ET2_1	724	726	PF00082	0.674
CLV_PCSK_PC1ET2_1	730	732	PF00082	0.610
CLV_PCSK_PC1ET2_1	742	744	PF00082	0.536
CLV_PCSK_PC7_1	403	409	PF00082	0.670
CLV_PCSK_SKI1_1	105	109	PF00082	0.678
CLV_PCSK_SKI1_1	28	32	PF00082	0.493
CLV_PCSK_SKI1_1	35	39	PF00082	0.458
CLV_PCSK_SKI1_1	51	55	PF00082	0.336
CLV_PCSK_SKI1_1	730	734	PF00082	0.691
CLV_PCSK_SKI1_1	749	753	PF00082	0.621
DEG_SCF_FBW7_2	214	221	PF00400	0.720
DOC_CKS1_1	870	875	PF01111	0.712
DOC_CYCLIN_yCln2_LP_2	920	923	PF00134	0.570
DOC_MAPK_gen_1	748	756	PF00069	0.535
DOC_MAPK_gen_1	774	782	PF00069	0.536
DOC_MAPK_MEF2A_6	46	54	PF00069	0.433
DOC_MAPK_MEF2A_6	545	554	PF00069	0.538
DOC_PP1_RVXF_1	49	55	PF00149	0.423
DOC_PP2B_LxvP_1	582	585	PF13499	0.722
DOC_PP2B_LxvP_1	920	923	PF13499	0.570
DOC_PP4_FxxP_1	414	417	PF00568	0.586
DOC_PP4_MxPP_1	647	650	PF00568	0.538
DOC_USP7_MATH_1	106	110	PF00917	0.781
DOC_USP7_MATH_1	127	131	PF00917	0.707
DOC_USP7_MATH_1	164	168	PF00917	0.698
DOC_USP7_MATH_1	325	329	PF00917	0.668
DOC_USP7_MATH_1	435	439	PF00917	0.627
DOC_USP7_MATH_1	537	541	PF00917	0.681
DOC_USP7_MATH_1	561	565	PF00917	0.631
DOC_USP7_MATH_1	6	10	PF00917	0.541
DOC_USP7_MATH_1	622	626	PF00917	0.655
DOC_USP7_MATH_1	633	637	PF00917	0.515
DOC_USP7_MATH_1	682	686	PF00917	0.611
DOC_USP7_MATH_1	713	717	PF00917	0.648
DOC_USP7_MATH_1	810	814	PF00917	0.661
DOC_USP7_MATH_1	82	86	PF00917	0.691
DOC_USP7_MATH_1	823	827	PF00917	0.547
DOC_USP7_MATH_1	858	862	PF00917	0.674
DOC_USP7_MATH_1	865	869	PF00917	0.636
DOC_USP7_MATH_1	894	898	PF00917	0.668
DOC_USP7_MATH_1	924	928	PF00917	0.607
DOC_USP7_UBL2_3	726	730	PF12436	0.634
DOC_WW_Pin1_4	168	173	PF00397	0.636
DOC_WW_Pin1_4	214	219	PF00397	0.721
DOC_WW_Pin1_4	271	276	PF00397	0.626
DOC_WW_Pin1_4	286	291	PF00397	0.648
DOC_WW_Pin1_4	305	310	PF00397	0.807
DOC_WW_Pin1_4	318	323	PF00397	0.589
DOC_WW_Pin1_4	336	341	PF00397	0.707
DOC_WW_Pin1_4	39	44	PF00397	0.530
DOC_WW_Pin1_4	431	436	PF00397	0.629
DOC_WW_Pin1_4	437	442	PF00397	0.621
DOC_WW_Pin1_4	484	489	PF00397	0.640
DOC_WW_Pin1_4	500	505	PF00397	0.639
DOC_WW_Pin1_4	507	512	PF00397	0.616
DOC_WW_Pin1_4	546	551	PF00397	0.653
DOC_WW_Pin1_4	565	570	PF00397	0.798
DOC_WW_Pin1_4	576	581	PF00397	0.616
DOC_WW_Pin1_4	592	597	PF00397	0.609
DOC_WW_Pin1_4	661	666	PF00397	0.754
DOC_WW_Pin1_4	70	75	PF00397	0.612
DOC_WW_Pin1_4	754	759	PF00397	0.753
DOC_WW_Pin1_4	763	768	PF00397	0.606
DOC_WW_Pin1_4	812	817	PF00397	0.636
DOC_WW_Pin1_4	869	874	PF00397	0.629
LIG_14-3-3_CanoR_1	24	30	PF00244	0.483
LIG_14-3-3_CanoR_1	361	365	PF00244	0.636
LIG_14-3-3_CanoR_1	410	415	PF00244	0.735
LIG_14-3-3_CanoR_1	542	552	PF00244	0.651
LIG_14-3-3_CanoR_1	621	627	PF00244	0.664
LIG_14-3-3_CanoR_1	659	665	PF00244	0.635
LIG_14-3-3_CanoR_1	690	698	PF00244	0.535
LIG_14-3-3_CanoR_1	798	807	PF00244	0.609
LIG_14-3-3_CanoR_1	821	829	PF00244	0.639
LIG_14-3-3_CanoR_1	840	845	PF00244	0.656
LIG_14-3-3_CanoR_1	871	880	PF00244	0.642
LIG_14-3-3_CanoR_1	931	939	PF00244	0.510
LIG_APCC_ABBA_1	50	55	PF00400	0.508
LIG_BRCT_BRCA1_1	874	878	PF00533	0.719
LIG_CtBP_PxDLS_1	441	445	PF00389	0.659
LIG_FHA_1	110	116	PF00498	0.657
LIG_FHA_1	229	235	PF00498	0.612
LIG_FHA_1	378	384	PF00498	0.696
LIG_FHA_1	40	46	PF00498	0.521
LIG_FHA_1	577	583	PF00498	0.678
LIG_FHA_1	626	632	PF00498	0.604
LIG_FHA_1	791	797	PF00498	0.674
LIG_FHA_1	803	809	PF00498	0.561
LIG_FHA_2	29	35	PF00498	0.543
LIG_FHA_2	347	353	PF00498	0.731
LIG_FHA_2	411	417	PF00498	0.671
LIG_LIR_Apic_2	369	375	PF02991	0.567
LIG_LIR_Apic_2	411	417	PF02991	0.586
LIG_LIR_Apic_2	436	442	PF02991	0.603
LIG_LIR_Apic_2	739	744	PF02991	0.562
LIG_LIR_Gen_1	455	465	PF02991	0.579
LIG_LIR_Gen_1	770	780	PF02991	0.536
LIG_LIR_Gen_1	839	850	PF02991	0.641
LIG_LIR_Gen_1	927	937	PF02991	0.588
LIG_LIR_Nem_3	422	428	PF02991	0.605
LIG_LIR_Nem_3	455	460	PF02991	0.636
LIG_LIR_Nem_3	770	775	PF02991	0.540
LIG_LIR_Nem_3	927	932	PF02991	0.543
LIG_LIR_Nem_3	933	939	PF02991	0.481
LIG_MYND_1	580	584	PF01753	0.675
LIG_NRP_CendR_1	950	953	PF00754	0.551
LIG_RPA_C_Fungi	894	906	PF08784	0.551
LIG_SH2_CRK	372	376	PF00017	0.633
LIG_SH2_CRK	391	395	PF00017	0.576
LIG_SH2_CRK	772	776	PF00017	0.619
LIG_SH2_GRB2like	372	375	PF00017	0.655
LIG_SH2_NCK_1	372	376	PF00017	0.633
LIG_SH2_SRC	372	375	PF00017	0.655
LIG_SH2_STAP1	940	944	PF00017	0.567
LIG_SH2_STAT3	803	806	PF00017	0.683
LIG_SH2_STAT5	25	28	PF00017	0.516
LIG_SH2_STAT5	610	613	PF00017	0.530
LIG_SH2_STAT5	65	68	PF00017	0.467
LIG_SH3_1	319	325	PF00018	0.602
LIG_SH3_2	485	490	PF14604	0.615
LIG_SH3_2	585	590	PF14604	0.662
LIG_SH3_2	816	821	PF14604	0.653
LIG_SH3_3	148	154	PF00018	0.633
LIG_SH3_3	224	230	PF00018	0.666
LIG_SH3_3	247	253	PF00018	0.643
LIG_SH3_3	309	315	PF00018	0.735
LIG_SH3_3	319	325	PF00018	0.609
LIG_SH3_3	337	343	PF00018	0.737
LIG_SH3_3	380	386	PF00018	0.650
LIG_SH3_3	464	470	PF00018	0.614
LIG_SH3_3	482	488	PF00018	0.533
LIG_SH3_3	508	514	PF00018	0.726
LIG_SH3_3	547	553	PF00018	0.641
LIG_SH3_3	569	575	PF00018	0.690
LIG_SH3_3	581	587	PF00018	0.631
LIG_SH3_3	761	767	PF00018	0.650
LIG_SH3_3	813	819	PF00018	0.663
LIG_SH3_3	885	891	PF00018	0.649
LIG_SH3_3	9	15	PF00018	0.566
LIG_SH3_CIN85_PxpxPR_1	382	387	PF14604	0.652
LIG_SUMO_SIM_par_1	194	200	PF11976	0.614
LIG_SUMO_SIM_par_1	230	236	PF11976	0.593
LIG_SUMO_SIM_par_1	851	857	PF11976	0.637
LIG_TRAF2_1	219	222	PF00917	0.593
LIG_TRAF2_1	31	34	PF00917	0.569
LIG_TYR_ITIM	423	428	PF00017	0.604
LIG_TYR_ITSM	768	775	PF00017	0.561
LIG_UBA3_1	254	262	PF00899	0.746
MOD_CDC14_SPxK_1	487	490	PF00782	0.655
MOD_CDC14_SPxK_1	595	598	PF00782	0.712
MOD_CDC14_SPxK_1	815	818	PF00782	0.637
MOD_CDK_SPK_2	507	512	PF00069	0.628
MOD_CDK_SPK_2	546	551	PF00069	0.708
MOD_CDK_SPK_2	70	75	PF00069	0.612
MOD_CDK_SPK_2	763	768	PF00069	0.636
MOD_CDK_SPK_2	869	874	PF00069	0.629
MOD_CDK_SPxK_1	214	220	PF00069	0.721
MOD_CDK_SPxK_1	484	490	PF00069	0.616
MOD_CDK_SPxK_1	592	598	PF00069	0.723
MOD_CDK_SPxK_1	812	818	PF00069	0.637
MOD_CDK_SPxxK_3	168	175	PF00069	0.639
MOD_CDK_SPxxK_3	39	46	PF00069	0.519
MOD_CDK_SPxxK_3	592	599	PF00069	0.622
MOD_CK1_1	10	16	PF00069	0.558
MOD_CK1_1	109	115	PF00069	0.610
MOD_CK1_1	139	145	PF00069	0.634
MOD_CK1_1	165	171	PF00069	0.687
MOD_CK1_1	17	23	PF00069	0.448
MOD_CK1_1	188	194	PF00069	0.593
MOD_CK1_1	199	205	PF00069	0.599
MOD_CK1_1	268	274	PF00069	0.772
MOD_CK1_1	345	351	PF00069	0.689
MOD_CK1_1	397	403	PF00069	0.697
MOD_CK1_1	625	631	PF00069	0.651
MOD_CK1_1	672	678	PF00069	0.653
MOD_CK1_1	70	76	PF00069	0.654
MOD_CK1_1	706	712	PF00069	0.634
MOD_CK1_1	790	796	PF00069	0.668
MOD_CK1_1	87	93	PF00069	0.550
MOD_CK2_1	28	34	PF00069	0.489
MOD_CK2_1	346	352	PF00069	0.729
MOD_CK2_1	410	416	PF00069	0.602
MOD_CK2_1	642	648	PF00069	0.633
MOD_CK2_1	898	904	PF00069	0.612
MOD_CK2_1	924	930	PF00069	0.655
MOD_GlcNHglycan	129	132	PF01048	0.656
MOD_GlcNHglycan	138	141	PF01048	0.553
MOD_GlcNHglycan	164	167	PF01048	0.688
MOD_GlcNHglycan	187	190	PF01048	0.668
MOD_GlcNHglycan	204	208	PF01048	0.517
MOD_GlcNHglycan	270	273	PF01048	0.716
MOD_GlcNHglycan	275	278	PF01048	0.665
MOD_GlcNHglycan	446	449	PF01048	0.714
MOD_GlcNHglycan	505	508	PF01048	0.705
MOD_GlcNHglycan	576	579	PF01048	0.749
MOD_GlcNHglycan	635	638	PF01048	0.642
MOD_GlcNHglycan	642	645	PF01048	0.609
MOD_GlcNHglycan	666	669	PF01048	0.635
MOD_GlcNHglycan	69	72	PF01048	0.523
MOD_GlcNHglycan	693	696	PF01048	0.695
MOD_GlcNHglycan	705	708	PF01048	0.572
MOD_GlcNHglycan	789	792	PF01048	0.703
MOD_GlcNHglycan	80	83	PF01048	0.670
MOD_GlcNHglycan	812	815	PF01048	0.690
MOD_GlcNHglycan	823	826	PF01048	0.662
MOD_GlcNHglycan	830	833	PF01048	0.583
MOD_GlcNHglycan	86	89	PF01048	0.738
MOD_GlcNHglycan	860	863	PF01048	0.652
MOD_GlcNHglycan	874	877	PF01048	0.569
MOD_GlcNHglycan	896	899	PF01048	0.636
MOD_GlcNHglycan	900	903	PF01048	0.620
MOD_GSK3_1	164	171	PF00069	0.695
MOD_GSK3_1	196	203	PF00069	0.616
MOD_GSK3_1	263	270	PF00069	0.700
MOD_GSK3_1	286	293	PF00069	0.770
MOD_GSK3_1	294	301	PF00069	0.619
MOD_GSK3_1	325	332	PF00069	0.712
MOD_GSK3_1	342	349	PF00069	0.648
MOD_GSK3_1	373	380	PF00069	0.638
MOD_GSK3_1	4	11	PF00069	0.617
MOD_GSK3_1	431	438	PF00069	0.681
MOD_GSK3_1	440	447	PF00069	0.707
MOD_GSK3_1	448	455	PF00069	0.599
MOD_GSK3_1	499	506	PF00069	0.649
MOD_GSK3_1	561	568	PF00069	0.661
MOD_GSK3_1	576	583	PF00069	0.558
MOD_GSK3_1	625	632	PF00069	0.630
MOD_GSK3_1	657	664	PF00069	0.624
MOD_GSK3_1	668	675	PF00069	0.662
MOD_GSK3_1	702	709	PF00069	0.650
MOD_GSK3_1	73	80	PF00069	0.645
MOD_GSK3_1	733	740	PF00069	0.624
MOD_GSK3_1	763	770	PF00069	0.559
MOD_GSK3_1	798	805	PF00069	0.571
MOD_GSK3_1	810	817	PF00069	0.623
MOD_GSK3_1	819	826	PF00069	0.633
MOD_GSK3_1	84	91	PF00069	0.689
MOD_GSK3_1	854	861	PF00069	0.665
MOD_GSK3_1	865	872	PF00069	0.567
MOD_GSK3_1	894	901	PF00069	0.595
MOD_LATS_1	406	412	PF00433	0.665
MOD_N-GLC_1	268	273	PF02516	0.654
MOD_N-GLC_1	293	298	PF02516	0.674
MOD_N-GLC_1	537	542	PF02516	0.644
MOD_NEK2_1	101	106	PF00069	0.632
MOD_NEK2_1	136	141	PF00069	0.668
MOD_NEK2_1	180	185	PF00069	0.667
MOD_NEK2_1	292	297	PF00069	0.738
MOD_NEK2_1	394	399	PF00069	0.803
MOD_NEK2_1	444	449	PF00069	0.753
MOD_NEK2_1	530	535	PF00069	0.647
MOD_NEK2_1	609	614	PF00069	0.567
MOD_NEK2_1	657	662	PF00069	0.619
MOD_NEK2_1	669	674	PF00069	0.613
MOD_NEK2_1	67	72	PF00069	0.556
MOD_NEK2_1	691	696	PF00069	0.560
MOD_NEK2_1	946	951	PF00069	0.612
MOD_NEK2_2	230	235	PF00069	0.616
MOD_NEK2_2	825	830	PF00069	0.662
MOD_NEK2_2	924	929	PF00069	0.543
MOD_PIKK_1	543	549	PF00454	0.742
MOD_PIKK_1	798	804	PF00454	0.570
MOD_PIKK_1	823	829	PF00454	0.663
MOD_PK_1	840	846	PF00069	0.510
MOD_PKA_1	28	34	PF00069	0.520
MOD_PKA_2	23	29	PF00069	0.452
MOD_PKA_2	284	290	PF00069	0.626
MOD_PKA_2	360	366	PF00069	0.630
MOD_PKA_2	409	415	PF00069	0.669
MOD_PKA_2	525	531	PF00069	0.606
MOD_PKA_2	633	639	PF00069	0.604
MOD_PKA_2	767	773	PF00069	0.662
MOD_PKA_2	82	88	PF00069	0.644
MOD_PKA_2	898	904	PF00069	0.637
MOD_PKA_2	930	936	PF00069	0.620
MOD_PKB_1	408	416	PF00069	0.648
MOD_Plk_1	7	13	PF00069	0.751
MOD_Plk_4	17	23	PF00069	0.485
MOD_Plk_4	191	197	PF00069	0.602
MOD_Plk_4	307	313	PF00069	0.704
MOD_Plk_4	790	796	PF00069	0.668
MOD_Plk_4	840	846	PF00069	0.648
MOD_Plk_4	924	930	PF00069	0.630
MOD_ProDKin_1	168	174	PF00069	0.638
MOD_ProDKin_1	214	220	PF00069	0.721
MOD_ProDKin_1	271	277	PF00069	0.626
MOD_ProDKin_1	286	292	PF00069	0.650
MOD_ProDKin_1	305	311	PF00069	0.807
MOD_ProDKin_1	318	324	PF00069	0.589
MOD_ProDKin_1	336	342	PF00069	0.708
MOD_ProDKin_1	39	45	PF00069	0.523
MOD_ProDKin_1	431	437	PF00069	0.629
MOD_ProDKin_1	484	490	PF00069	0.641
MOD_ProDKin_1	500	506	PF00069	0.641
MOD_ProDKin_1	507	513	PF00069	0.616
MOD_ProDKin_1	546	552	PF00069	0.653
MOD_ProDKin_1	565	571	PF00069	0.800
MOD_ProDKin_1	576	582	PF00069	0.619
MOD_ProDKin_1	592	598	PF00069	0.606
MOD_ProDKin_1	661	667	PF00069	0.755
MOD_ProDKin_1	70	76	PF00069	0.619
MOD_ProDKin_1	754	760	PF00069	0.754
MOD_ProDKin_1	763	769	PF00069	0.605
MOD_ProDKin_1	812	818	PF00069	0.637
MOD_ProDKin_1	869	875	PF00069	0.629
TRG_DiLeu_BaEn_1	32	37	PF01217	0.454
TRG_DiLeu_BaEn_3	32	38	PF01217	0.421
TRG_DiLeu_BaEn_4	33	39	PF01217	0.470
TRG_DiLeu_BaLyEn_6	250	255	PF01217	0.619
TRG_DiLeu_LyEn_5	32	37	PF01217	0.454
TRG_ENDOCYTIC_2	391	394	PF00928	0.665
TRG_ENDOCYTIC_2	425	428	PF00928	0.612
TRG_ENDOCYTIC_2	772	775	PF00928	0.606
TRG_ENDOCYTIC_2	842	845	PF00928	0.637
TRG_ENDOCYTIC_2	936	939	PF00928	0.514
TRG_ER_diArg_1	182	185	PF00400	0.619
TRG_ER_diArg_1	234	237	PF00400	0.681
TRG_ER_diArg_1	617	619	PF00400	0.516
TRG_ER_diArg_1	950	953	PF00400	0.565
TRG_NLS_MonoCore_2	722	727	PF00514	0.669
TRG_NLS_MonoExtC_3	722	728	PF00514	0.664
TRG_NLS_MonoExtN_4	522	527	PF00514	0.597
TRG_NLS_MonoExtN_4	721	727	PF00514	0.630
TRG_Pf-PMV_PEXEL_1	28	32	PF00026	0.493
TRG_Pf-PMV_PEXEL_1	885	890	PF00026	0.656

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYQ7	Leptomonas seymouri	31%	82%
A4H9P4	Leishmania braziliensis	61%	100%
A4HY11	Leishmania infantum	99%	100%
E9ARS5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4QDP8	Leishmania major	87%	100%