LeishMANIAdb
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HJURP_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
HJURP_C domain-containing protein
Gene product:
conserved protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8IAY2_LEIDO
TriTrypDb:
LdBPK_100130.1 * , LdCL_100006500 , LDHU3_10.0230
Length:
372

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0010494 cytoplasmic stress granule 5 1
GO:0035770 ribonucleoprotein granule 3 1
GO:0036464 cytoplasmic ribonucleoprotein granule 4 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0099080 supramolecular complex 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A0A3Q8IAY2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IAY2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
DEG_SCF_FBW7_1 263 268 PF00400 0.543
DEG_SPOP_SBC_1 271 275 PF00917 0.651
DOC_CDC14_PxL_1 184 192 PF14671 0.643
DOC_CKS1_1 169 174 PF01111 0.677
DOC_CKS1_1 266 271 PF01111 0.555
DOC_PP2B_LxvP_1 152 155 PF13499 0.634
DOC_USP7_MATH_1 23 27 PF00917 0.681
DOC_USP7_MATH_1 270 274 PF00917 0.654
DOC_USP7_MATH_1 289 293 PF00917 0.488
DOC_USP7_MATH_1 312 316 PF00917 0.678
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PCX5 Leptomonas seymouri 57% 100%
A4H5Z6 Leishmania braziliensis 79% 99%
A4HUC2 Leishmania infantum 99% 99%
C9ZVG8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AN21 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4QHK5 Leishmania major 96% 100%
V5BE36 Trypanosoma cruzi 35% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS