Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8IAW0_LEIDO

TriTrypDb:

LdCL_170021700 , LDHU3_27.2590

Length:

330

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IAW0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IAW0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	287	291	PF00656	0.422
CLV_C14_Caspase3-7	293	297	PF00656	0.413
CLV_C14_Caspase3-7	307	311	PF00656	0.388
CLV_NRD_NRD_1	225	227	PF00675	0.438
CLV_NRD_NRD_1	240	242	PF00675	0.402
CLV_NRD_NRD_1	321	323	PF00675	0.642
CLV_PCSK_FUR_1	238	242	PF00082	0.407
CLV_PCSK_KEX2_1	108	110	PF00082	0.627
CLV_PCSK_KEX2_1	224	226	PF00082	0.436
CLV_PCSK_KEX2_1	240	242	PF00082	0.420
CLV_PCSK_KEX2_1	321	323	PF00082	0.644
CLV_PCSK_KEX2_1	90	92	PF00082	0.472
CLV_PCSK_PC1ET2_1	108	110	PF00082	0.627
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.441
CLV_PCSK_PC7_1	236	242	PF00082	0.412
CLV_PCSK_SKI1_1	154	158	PF00082	0.552
CLV_PCSK_SKI1_1	169	173	PF00082	0.415
CLV_PCSK_SKI1_1	19	23	PF00082	0.440
DEG_SCF_FBW7_1	275	281	PF00400	0.400
DEG_SCF_SKP2-CKS1_1	153	160	PF00560	0.575
DOC_CDC14_PxL_1	263	271	PF14671	0.731
DOC_CKS1_1	275	280	PF01111	0.399
DOC_CYCLIN_RxL_1	14	24	PF00134	0.632
DOC_CYCLIN_RxL_1	238	251	PF00134	0.573
DOC_MAPK_gen_1	160	168	PF00069	0.544
DOC_MAPK_gen_1	238	248	PF00069	0.582
DOC_MAPK_MEF2A_6	48	56	PF00069	0.630
DOC_PP1_RVXF_1	17	24	PF00149	0.636
DOC_PP1_RVXF_1	242	249	PF00149	0.553
DOC_PP1_RVXF_1	298	305	PF00149	0.423
DOC_PP2B_LxvP_1	256	259	PF13499	0.249
DOC_PP2B_LxvP_1	80	83	PF13499	0.643
DOC_PP4_MxPP_1	156	159	PF00568	0.558
DOC_USP7_MATH_1	116	120	PF00917	0.769
DOC_USP7_MATH_1	265	269	PF00917	0.578
DOC_USP7_MATH_1	276	280	PF00917	0.460
DOC_WW_Pin1_4	154	159	PF00397	0.751
DOC_WW_Pin1_4	274	279	PF00397	0.547
DOC_WW_Pin1_4	288	293	PF00397	0.397
DOC_WW_Pin1_4	295	300	PF00397	0.411
DOC_WW_Pin1_4	75	80	PF00397	0.641
LIG_14-3-3_CanoR_1	109	114	PF00244	0.715
LIG_14-3-3_CanoR_1	19	24	PF00244	0.641
LIG_14-3-3_CanoR_1	244	249	PF00244	0.435
LIG_14-3-3_CanoR_1	91	97	PF00244	0.800
LIG_BIR_II_1	1	5	PF00653	0.638
LIG_BRCT_BRCA1_1	246	250	PF00533	0.249
LIG_BRCT_BRCA1_1	267	271	PF00533	0.400
LIG_FHA_2	305	311	PF00498	0.420
LIG_Integrin_isoDGR_2	152	154	PF01839	0.399
LIG_LIR_Apic_2	134	138	PF02991	0.586
LIG_LIR_Apic_2	78	84	PF02991	0.635
LIG_LIR_Gen_1	247	258	PF02991	0.349
LIG_LIR_Gen_1	298	309	PF02991	0.423
LIG_LIR_Nem_3	22	26	PF02991	0.643
LIG_LIR_Nem_3	247	253	PF02991	0.249
LIG_LIR_Nem_3	298	304	PF02991	0.422
LIG_SH2_CRK	135	139	PF00017	0.587
LIG_SH2_GRB2like	301	304	PF00017	0.425
LIG_SH2_NCK_1	135	139	PF00017	0.587
LIG_SH2_STAP1	194	198	PF00017	0.576
LIG_SH2_STAT5	130	133	PF00017	0.730
LIG_SH2_STAT5	135	138	PF00017	0.759
LIG_SH2_STAT5	301	304	PF00017	0.425
LIG_SH3_1	236	242	PF00018	0.612
LIG_SH3_2	239	244	PF14604	0.774
LIG_SH3_3	236	242	PF00018	0.692
LIG_WRC_WIRS_1	245	250	PF05994	0.249
MOD_CDK_SPK_2	295	300	PF00069	0.423
MOD_CDK_SPxK_1	154	160	PF00069	0.572
MOD_CDK_SPxxK_3	288	295	PF00069	0.419
MOD_CK1_1	128	134	PF00069	0.715
MOD_CK1_1	218	224	PF00069	0.630
MOD_CK1_1	86	92	PF00069	0.756
MOD_CK1_1	93	99	PF00069	0.809
MOD_CK2_1	189	195	PF00069	0.579
MOD_GlcNHglycan	114	117	PF01048	0.426
MOD_GlcNHglycan	127	130	PF01048	0.395
MOD_GlcNHglycan	143	146	PF01048	0.522
MOD_GlcNHglycan	271	274	PF01048	0.602
MOD_GlcNHglycan	92	95	PF01048	0.488
MOD_GSK3_1	112	119	PF00069	0.692
MOD_GSK3_1	15	22	PF00069	0.734
MOD_GSK3_1	179	186	PF00069	0.552
MOD_GSK3_1	204	211	PF00069	0.578
MOD_GSK3_1	244	251	PF00069	0.435
MOD_GSK3_1	265	272	PF00069	0.494
MOD_GSK3_1	274	281	PF00069	0.508
MOD_GSK3_1	28	35	PF00069	0.715
MOD_GSK3_1	284	291	PF00069	0.401
MOD_GSK3_1	317	324	PF00069	0.443
MOD_GSK3_1	82	89	PF00069	0.796
MOD_N-GLC_1	302	307	PF02516	0.624
MOD_NEK2_1	204	209	PF00069	0.574
MOD_NEK2_1	21	26	PF00069	0.642
MOD_NEK2_1	248	253	PF00069	0.417
MOD_NEK2_1	269	274	PF00069	0.465
MOD_NEK2_1	304	309	PF00069	0.469
MOD_NEK2_2	284	289	PF00069	0.602
MOD_PIKK_1	218	224	PF00454	0.630
MOD_PIKK_1	278	284	PF00454	0.591
MOD_PKA_1	224	230	PF00069	0.639
MOD_PKA_1	321	327	PF00069	0.446
MOD_PKA_1	90	96	PF00069	0.621
MOD_PKA_2	104	110	PF00069	0.601
MOD_PKA_2	125	131	PF00069	0.593
MOD_PKA_2	161	167	PF00069	0.723
MOD_PKA_2	224	230	PF00069	0.639
MOD_PKA_2	294	300	PF00069	0.422
MOD_PKA_2	317	323	PF00069	0.442
MOD_PKA_2	86	92	PF00069	0.796
MOD_Plk_1	194	200	PF00069	0.575
MOD_Plk_2-3	290	296	PF00069	0.598
MOD_Plk_4	136	142	PF00069	0.756
MOD_Plk_4	244	250	PF00069	0.435
MOD_Plk_4	265	271	PF00069	0.465
MOD_ProDKin_1	154	160	PF00069	0.751
MOD_ProDKin_1	274	280	PF00069	0.549
MOD_ProDKin_1	288	294	PF00069	0.397
MOD_ProDKin_1	295	301	PF00069	0.412
MOD_ProDKin_1	75	81	PF00069	0.643
TRG_DiLeu_BaEn_1	117	122	PF01217	0.610
TRG_DiLeu_BaLyEn_6	241	246	PF01217	0.578
TRG_ENDOCYTIC_2	301	304	PF00928	0.514
TRG_ER_diArg_1	224	226	PF00400	0.636
TRG_ER_diArg_1	235	238	PF00400	0.625
TRG_ER_diArg_1	239	241	PF00400	0.600
TRG_NLS_Bipartite_1	90	112	PF00514	0.624
TRG_NLS_MonoExtN_4	105	112	PF00514	0.816

Homologs


Protein	Taxonomy	Sequence identity	Coverage
Q4QET1	Leishmania major	43%	100%