LeishMANIAdb
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Pentamidine resistance protein 1

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Pentamidine resistance protein 1
Gene product:
ABC-thiol transporter (fragment)
Species:
Leishmania donovani
UniProt:
A0A3Q8IAV7_LEIDO
TriTrypDb:
LdBPK_230290.1 * , LdBPK_340690.1 * , LdCL_230007800 , LDHU3_23.0440
Length:
1571

Annotations

LeishMANIAdb annotations

Multidrug resistance transporters, involved in active transport of various unidentified small-molecule substrates.. ABC transporters belonging to subfamily C.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 63
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 36
NetGPI no yes: 0, no: 36
Cellular components
Term Name Level Count
GO:0016020 membrane 2 37
GO:0110165 cellular anatomical entity 1 37
GO:0043226 organelle 2 1
GO:0043229 intracellular organelle 3 1

Expansion

Sequence features

A0A3Q8IAV7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 7
GO:0009987 cellular process 1 7
GO:0051179 localization 1 7
GO:0051234 establishment of localization 2 7
GO:0055085 transmembrane transport 2 7
GO:0010035 response to inorganic substance 3 1
GO:0010038 response to metal ion 4 1
GO:0042221 response to chemical 2 1
GO:0050896 response to stimulus 1 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 37
GO:0003824 catalytic activity 1 12
GO:0005215 transporter activity 1 37
GO:0005488 binding 1 37
GO:0005524 ATP binding 5 37
GO:0015399 primary active transmembrane transporter activity 4 37
GO:0016787 hydrolase activity 2 12
GO:0017076 purine nucleotide binding 4 37
GO:0022804 active transmembrane transporter activity 3 37
GO:0022857 transmembrane transporter activity 2 37
GO:0030554 adenyl nucleotide binding 5 37
GO:0032553 ribonucleotide binding 3 37
GO:0032555 purine ribonucleotide binding 4 37
GO:0032559 adenyl ribonucleotide binding 5 37
GO:0035639 purine ribonucleoside triphosphate binding 4 37
GO:0036094 small molecule binding 2 37
GO:0042626 ATPase-coupled transmembrane transporter activity 2 37
GO:0043167 ion binding 2 37
GO:0043168 anion binding 3 37
GO:0097159 organic cyclic compound binding 2 37
GO:0097367 carbohydrate derivative binding 2 37
GO:0140359 ABC-type transporter activity 3 37
GO:0140657 ATP-dependent activity 1 37
GO:1901265 nucleoside phosphate binding 3 37
GO:1901363 heterocyclic compound binding 2 37

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1080 1084 PF00656 0.481
CLV_C14_Caspase3-7 1443 1447 PF00656 0.448
CLV_C14_Caspase3-7 625 629 PF00656 0.506
CLV_C14_Caspase3-7 743 747 PF00656 0.504
CLV_C14_Caspase3-7 818 822 PF00656 0.517
CLV_C14_Caspase3-7 890 894 PF00656 0.655
CLV_C14_Caspase3-7 899 903 PF00656 0.675
CLV_NRD_NRD_1 1135 1137 PF00675 0.243
CLV_NRD_NRD_1 1174 1176 PF00675 0.298
CLV_NRD_NRD_1 127 129 PF00675 0.384
CLV_NRD_NRD_1 1393 1395 PF00675 0.363
CLV_NRD_NRD_1 142 144 PF00675 0.306
CLV_NRD_NRD_1 192 194 PF00675 0.447
CLV_NRD_NRD_1 613 615 PF00675 0.369
CLV_PCSK_FUR_1 190 194 PF00082 0.392
CLV_PCSK_FUR_1 440 444 PF00082 0.320
CLV_PCSK_KEX2_1 1135 1137 PF00082 0.256
CLV_PCSK_KEX2_1 1174 1176 PF00082 0.244
CLV_PCSK_KEX2_1 1393 1395 PF00082 0.286
CLV_PCSK_KEX2_1 142 144 PF00082 0.321
CLV_PCSK_KEX2_1 192 194 PF00082 0.442
CLV_PCSK_KEX2_1 442 444 PF00082 0.313
CLV_PCSK_KEX2_1 551 553 PF00082 0.287
CLV_PCSK_KEX2_1 612 614 PF00082 0.354
CLV_PCSK_PC1ET2_1 442 444 PF00082 0.295
CLV_PCSK_PC1ET2_1 551 553 PF00082 0.254
CLV_PCSK_SKI1_1 1027 1031 PF00082 0.330
CLV_PCSK_SKI1_1 103 107 PF00082 0.249
CLV_PCSK_SKI1_1 1044 1048 PF00082 0.285
CLV_PCSK_SKI1_1 1135 1139 PF00082 0.322
CLV_PCSK_SKI1_1 1468 1472 PF00082 0.315
CLV_PCSK_SKI1_1 193 197 PF00082 0.291
CLV_PCSK_SKI1_1 343 347 PF00082 0.251
CLV_PCSK_SKI1_1 452 456 PF00082 0.272
CLV_PCSK_SKI1_1 551 555 PF00082 0.300
CLV_PCSK_SKI1_1 680 684 PF00082 0.288
CLV_PCSK_SKI1_1 865 869 PF00082 0.328
CLV_PCSK_SKI1_1 943 947 PF00082 0.339
CLV_Separin_Metazoa 681 685 PF03568 0.482
DEG_APCC_DBOX_1 1043 1051 PF00400 0.493
DEG_APCC_DBOX_1 1328 1336 PF00400 0.506
DEG_APCC_KENBOX_2 888 892 PF00400 0.533
DEG_COP1_1 1268 1277 PF00400 0.527
DEG_SCF_FBW7_2 76 83 PF00400 0.652
DOC_CKS1_1 1 6 PF01111 0.513
DOC_CKS1_1 194 199 PF01111 0.491
DOC_CYCLIN_RxL_1 1465 1475 PF00134 0.537
DOC_CYCLIN_yClb5_NLxxxL_5 1037 1046 PF00134 0.472
DOC_CYCLIN_yCln2_LP_2 277 283 PF00134 0.266
DOC_CYCLIN_yCln2_LP_2 813 819 PF00134 0.465
DOC_MAPK_gen_1 1327 1336 PF00069 0.517
DOC_MAPK_HePTP_8 1324 1336 PF00069 0.533
DOC_MAPK_HePTP_8 429 441 PF00069 0.494
DOC_MAPK_MEF2A_6 1191 1199 PF00069 0.515
DOC_MAPK_MEF2A_6 1327 1336 PF00069 0.531
DOC_MAPK_MEF2A_6 1359 1366 PF00069 0.492
DOC_MAPK_MEF2A_6 432 441 PF00069 0.434
DOC_MAPK_NFAT4_5 1329 1337 PF00069 0.511
DOC_MAPK_NFAT4_5 1359 1367 PF00069 0.492
DOC_MAPK_RevD_3 538 552 PF00069 0.296
DOC_PP1_RVXF_1 1194 1200 PF00149 0.502
DOC_PP1_RVXF_1 1335 1342 PF00149 0.496
DOC_PP1_RVXF_1 397 404 PF00149 0.290
DOC_PP1_RVXF_1 450 457 PF00149 0.472
DOC_PP1_RVXF_1 528 534 PF00149 0.339
DOC_PP1_RVXF_1 863 869 PF00149 0.581
DOC_PP2B_LxvP_1 114 117 PF13499 0.665
DOC_PP2B_LxvP_1 277 280 PF13499 0.255
DOC_PP2B_LxvP_1 688 691 PF13499 0.471
DOC_PP4_FxxP_1 1022 1025 PF00568 0.388
DOC_PP4_FxxP_1 404 407 PF00568 0.208
DOC_PP4_FxxP_1 534 537 PF00568 0.209
DOC_USP7_MATH_1 105 109 PF00917 0.627
DOC_USP7_MATH_1 1053 1057 PF00917 0.472
DOC_USP7_MATH_1 117 121 PF00917 0.614
DOC_USP7_MATH_1 1439 1443 PF00917 0.458
DOC_USP7_MATH_1 158 162 PF00917 0.540
DOC_USP7_MATH_1 355 359 PF00917 0.410
DOC_USP7_MATH_1 629 633 PF00917 0.572
DOC_USP7_MATH_1 701 705 PF00917 0.500
DOC_USP7_MATH_1 726 730 PF00917 0.485
DOC_USP7_MATH_1 796 800 PF00917 0.479
DOC_USP7_MATH_1 876 880 PF00917 0.597
DOC_USP7_MATH_1 934 938 PF00917 0.586
DOC_WW_Pin1_4 1021 1026 PF00397 0.283
DOC_WW_Pin1_4 1058 1063 PF00397 0.465
DOC_WW_Pin1_4 1140 1145 PF00397 0.473
DOC_WW_Pin1_4 1302 1307 PF00397 0.634
DOC_WW_Pin1_4 1534 1539 PF00397 0.577
DOC_WW_Pin1_4 193 198 PF00397 0.560
DOC_WW_Pin1_4 244 249 PF00397 0.585
DOC_WW_Pin1_4 492 497 PF00397 0.350
DOC_WW_Pin1_4 630 635 PF00397 0.656
DOC_WW_Pin1_4 7 12 PF00397 0.510
DOC_WW_Pin1_4 76 81 PF00397 0.636
LIG_14-3-3_CanoR_1 1003 1011 PF00244 0.317
LIG_14-3-3_CanoR_1 1054 1058 PF00244 0.429
LIG_14-3-3_CanoR_1 1157 1163 PF00244 0.583
LIG_14-3-3_CanoR_1 119 125 PF00244 0.673
LIG_14-3-3_CanoR_1 1219 1228 PF00244 0.240
LIG_14-3-3_CanoR_1 1247 1253 PF00244 0.515
LIG_14-3-3_CanoR_1 1337 1342 PF00244 0.471
LIG_14-3-3_CanoR_1 1393 1399 PF00244 0.479
LIG_14-3-3_CanoR_1 1437 1445 PF00244 0.541
LIG_14-3-3_CanoR_1 1514 1519 PF00244 0.500
LIG_14-3-3_CanoR_1 230 240 PF00244 0.473
LIG_14-3-3_CanoR_1 432 437 PF00244 0.479
LIG_14-3-3_CanoR_1 440 448 PF00244 0.504
LIG_14-3-3_CanoR_1 530 534 PF00244 0.280
LIG_14-3-3_CanoR_1 552 557 PF00244 0.508
LIG_14-3-3_CanoR_1 600 605 PF00244 0.520
LIG_14-3-3_CanoR_1 606 610 PF00244 0.550
LIG_14-3-3_CanoR_1 797 801 PF00244 0.483
LIG_14-3-3_CanoR_1 842 852 PF00244 0.501
LIG_Actin_WH2_2 1459 1474 PF00022 0.489
LIG_Actin_WH2_2 989 1005 PF00022 0.188
LIG_AP2alpha_2 1415 1417 PF02296 0.521
LIG_APCC_ABBA_1 1414 1419 PF00400 0.556
LIG_APCC_ABBA_1 214 219 PF00400 0.424
LIG_BIR_II_1 1 5 PF00653 0.515
LIG_BIR_III_1 1 5 PF00653 0.512
LIG_BIR_III_2 493 497 PF00653 0.199
LIG_BIR_III_3 1 5 PF00653 0.512
LIG_BIR_III_4 573 577 PF00653 0.397
LIG_BRCT_BRCA1_1 1142 1146 PF00533 0.450
LIG_BRCT_BRCA1_1 1317 1321 PF00533 0.529
LIG_eIF4E_1 1009 1015 PF01652 0.292
LIG_eIF4E_1 1162 1168 PF01652 0.393
LIG_FHA_1 104 110 PF00498 0.580
LIG_FHA_1 1058 1064 PF00498 0.433
LIG_FHA_1 1132 1138 PF00498 0.472
LIG_FHA_1 1203 1209 PF00498 0.358
LIG_FHA_1 1231 1237 PF00498 0.334
LIG_FHA_1 1264 1270 PF00498 0.515
LIG_FHA_1 1294 1300 PF00498 0.642
LIG_FHA_1 1359 1365 PF00498 0.569
LIG_FHA_1 1482 1488 PF00498 0.467
LIG_FHA_1 234 240 PF00498 0.636
LIG_FHA_1 304 310 PF00498 0.354
LIG_FHA_1 36 42 PF00498 0.562
LIG_FHA_1 408 414 PF00498 0.413
LIG_FHA_1 442 448 PF00498 0.472
LIG_FHA_1 493 499 PF00498 0.341
LIG_FHA_1 520 526 PF00498 0.277
LIG_FHA_1 548 554 PF00498 0.494
LIG_FHA_1 633 639 PF00498 0.718
LIG_FHA_1 694 700 PF00498 0.482
LIG_FHA_1 77 83 PF00498 0.538
LIG_FHA_1 839 845 PF00498 0.531
LIG_FHA_1 950 956 PF00498 0.508
LIG_FHA_1 977 983 PF00498 0.296
LIG_FHA_1 997 1003 PF00498 0.246
LIG_FHA_2 1078 1084 PF00498 0.516
LIG_FHA_2 108 114 PF00498 0.611
LIG_FHA_2 1145 1151 PF00498 0.494
LIG_FHA_2 1235 1241 PF00498 0.389
LIG_FHA_2 1289 1295 PF00498 0.642
LIG_FHA_2 41 47 PF00498 0.611
LIG_FHA_2 553 559 PF00498 0.551
LIG_FHA_2 741 747 PF00498 0.429
LIG_FHA_2 79 85 PF00498 0.564
LIG_FHA_2 876 882 PF00498 0.527
LIG_FHA_2 908 914 PF00498 0.579
LIG_FHA_2 944 950 PF00498 0.540
LIG_GBD_Chelix_1 539 547 PF00786 0.242
LIG_GSK3_LRP6_1 244 249 PF00069 0.522
LIG_HCF-1_HBM_1 1270 1273 PF13415 0.412
LIG_Integrin_isoDGR_2 1380 1382 PF01839 0.250
LIG_LIR_Apic_2 184 188 PF02991 0.558
LIG_LIR_Apic_2 532 537 PF02991 0.350
LIG_LIR_Gen_1 1008 1019 PF02991 0.246
LIG_LIR_Gen_1 1083 1093 PF02991 0.470
LIG_LIR_Gen_1 1143 1153 PF02991 0.464
LIG_LIR_Gen_1 1177 1188 PF02991 0.485
LIG_LIR_Gen_1 1365 1372 PF02991 0.459
LIG_LIR_Gen_1 1424 1434 PF02991 0.515
LIG_LIR_Gen_1 1475 1485 PF02991 0.489
LIG_LIR_Gen_1 1504 1512 PF02991 0.572
LIG_LIR_Gen_1 1547 1556 PF02991 0.553
LIG_LIR_Gen_1 249 260 PF02991 0.511
LIG_LIR_Gen_1 3 11 PF02991 0.525
LIG_LIR_Gen_1 856 861 PF02991 0.463
LIG_LIR_Gen_1 871 880 PF02991 0.575
LIG_LIR_LC3C_4 495 500 PF02991 0.304
LIG_LIR_Nem_3 1008 1014 PF02991 0.250
LIG_LIR_Nem_3 1083 1088 PF02991 0.470
LIG_LIR_Nem_3 1143 1149 PF02991 0.464
LIG_LIR_Nem_3 1177 1183 PF02991 0.485
LIG_LIR_Nem_3 1189 1195 PF02991 0.495
LIG_LIR_Nem_3 1318 1324 PF02991 0.513
LIG_LIR_Nem_3 1365 1369 PF02991 0.431
LIG_LIR_Nem_3 141 147 PF02991 0.473
LIG_LIR_Nem_3 1424 1429 PF02991 0.524
LIG_LIR_Nem_3 1501 1506 PF02991 0.617
LIG_LIR_Nem_3 211 217 PF02991 0.597
LIG_LIR_Nem_3 249 255 PF02991 0.531
LIG_LIR_Nem_3 284 289 PF02991 0.238
LIG_LIR_Nem_3 3 9 PF02991 0.529
LIG_LIR_Nem_3 517 523 PF02991 0.270
LIG_LIR_Nem_3 532 536 PF02991 0.289
LIG_LIR_Nem_3 618 624 PF02991 0.487
LIG_LIR_Nem_3 856 860 PF02991 0.449
LIG_LIR_Nem_3 871 875 PF02991 0.496
LIG_LIR_Nem_3 958 963 PF02991 0.487
LIG_NRBOX 391 397 PF00104 0.245
LIG_PCNA_yPIPBox_3 1023 1036 PF02747 0.176
LIG_PCNA_yPIPBox_3 826 840 PF02747 0.556
LIG_Pex14_1 378 382 PF04695 0.275
LIG_Pex14_1 459 463 PF04695 0.456
LIG_Pex14_1 96 100 PF04695 0.517
LIG_Pex14_2 1018 1022 PF04695 0.242
LIG_Pex14_2 341 345 PF04695 0.461
LIG_PTB_Apo_2 482 489 PF02174 0.393
LIG_SH2_CRK 1180 1184 PF00017 0.457
LIG_SH2_CRK 1506 1510 PF00017 0.561
LIG_SH2_CRK 1521 1525 PF00017 0.426
LIG_SH2_CRK 675 679 PF00017 0.436
LIG_SH2_GRB2like 805 808 PF00017 0.544
LIG_SH2_NCK_1 1506 1510 PF00017 0.552
LIG_SH2_NCK_1 321 325 PF00017 0.512
LIG_SH2_PTP2 1011 1014 PF00017 0.372
LIG_SH2_PTP2 857 860 PF00017 0.451
LIG_SH2_SRC 1009 1012 PF00017 0.251
LIG_SH2_SRC 289 292 PF00017 0.244
LIG_SH2_SRC 321 324 PF00017 0.494
LIG_SH2_SRC 589 592 PF00017 0.482
LIG_SH2_STAP1 1180 1184 PF00017 0.451
LIG_SH2_STAP1 1265 1269 PF00017 0.497
LIG_SH2_STAP1 1521 1525 PF00017 0.466
LIG_SH2_STAP1 154 158 PF00017 0.440
LIG_SH2_STAP1 217 221 PF00017 0.396
LIG_SH2_STAP1 872 876 PF00017 0.639
LIG_SH2_STAT3 1087 1090 PF00017 0.290
LIG_SH2_STAT3 169 172 PF00017 0.476
LIG_SH2_STAT3 191 194 PF00017 0.582
LIG_SH2_STAT3 717 720 PF00017 0.511
LIG_SH2_STAT3 732 735 PF00017 0.472
LIG_SH2_STAT5 100 103 PF00017 0.538
LIG_SH2_STAT5 1009 1012 PF00017 0.247
LIG_SH2_STAT5 1013 1016 PF00017 0.296
LIG_SH2_STAT5 1033 1036 PF00017 0.362
LIG_SH2_STAT5 1085 1088 PF00017 0.365
LIG_SH2_STAT5 1091 1094 PF00017 0.336
LIG_SH2_STAT5 1265 1268 PF00017 0.541
LIG_SH2_STAT5 1273 1276 PF00017 0.526
LIG_SH2_STAT5 147 150 PF00017 0.522
LIG_SH2_STAT5 1506 1509 PF00017 0.552
LIG_SH2_STAT5 169 172 PF00017 0.594
LIG_SH2_STAT5 221 224 PF00017 0.549
LIG_SH2_STAT5 232 235 PF00017 0.526
LIG_SH2_STAT5 285 288 PF00017 0.250
LIG_SH2_STAT5 289 292 PF00017 0.250
LIG_SH2_STAT5 379 382 PF00017 0.324
LIG_SH2_STAT5 589 592 PF00017 0.458
LIG_SH2_STAT5 732 735 PF00017 0.477
LIG_SH2_STAT5 78 81 PF00017 0.661
LIG_SH2_STAT5 811 814 PF00017 0.465
LIG_SH2_STAT5 857 860 PF00017 0.473
LIG_SH2_STAT5 960 963 PF00017 0.486
LIG_SH3_3 1297 1303 PF00018 0.569
LIG_SH3_3 1397 1403 PF00018 0.471
LIG_SH3_3 239 245 PF00018 0.563
LIG_SH3_3 411 417 PF00018 0.266
LIG_SH3_3 554 560 PF00018 0.628
LIG_SH3_3 633 639 PF00018 0.652
LIG_SH3_5 853 857 PF00018 0.498
LIG_SUMO_SIM_anti_2 1097 1103 PF11976 0.244
LIG_SUMO_SIM_anti_2 1522 1528 PF11976 0.494
LIG_SUMO_SIM_anti_2 410 415 PF11976 0.438
LIG_SUMO_SIM_anti_2 522 528 PF11976 0.285
LIG_SUMO_SIM_anti_2 856 862 PF11976 0.476
LIG_SUMO_SIM_par_1 1097 1103 PF11976 0.309
LIG_SUMO_SIM_par_1 1226 1231 PF11976 0.321
LIG_SUMO_SIM_par_1 1296 1302 PF11976 0.570
LIG_SUMO_SIM_par_1 1360 1365 PF11976 0.477
LIG_SUMO_SIM_par_1 279 284 PF11976 0.305
LIG_SUMO_SIM_par_1 409 415 PF11976 0.293
LIG_SUMO_SIM_par_1 536 541 PF11976 0.285
LIG_TRAF2_1 879 882 PF00917 0.590
LIG_TRAF2_1 946 949 PF00917 0.549
LIG_TRFH_1 675 679 PF08558 0.416
LIG_TYR_ITIM 1178 1183 PF00017 0.209
LIG_TYR_ITIM 92 97 PF00017 0.336
LIG_UBA3_1 1210 1216 PF00899 0.233
LIG_UBA3_1 250 256 PF00899 0.365
LIG_UBA3_1 543 551 PF00899 0.191
LIG_WRC_WIRS_1 1203 1208 PF05994 0.348
LIG_WRC_WIRS_1 1363 1368 PF05994 0.302
LIG_WRC_WIRS_1 553 558 PF05994 0.469
LIG_WRC_WIRS_1 977 982 PF05994 0.199
LIG_WRPW_2 214 217 PF00400 0.239
LIG_WW_1 188 191 PF00397 0.322
LIG_WW_3 187 191 PF00397 0.329
MOD_CDC14_SPxK_1 1024 1027 PF00782 0.238
MOD_CDK_SPK_2 1534 1539 PF00069 0.558
MOD_CDK_SPxK_1 1021 1027 PF00069 0.283
MOD_CDK_SPxxK_3 1058 1065 PF00069 0.309
MOD_CK1_1 1005 1011 PF00069 0.310
MOD_CK1_1 1094 1100 PF00069 0.259
MOD_CK1_1 118 124 PF00069 0.630
MOD_CK1_1 1221 1227 PF00069 0.221
MOD_CK1_1 1305 1311 PF00069 0.552
MOD_CK1_1 1357 1363 PF00069 0.319
MOD_CK1_1 1454 1460 PF00069 0.366
MOD_CK1_1 1501 1507 PF00069 0.289
MOD_CK1_1 235 241 PF00069 0.394
MOD_CK1_1 325 331 PF00069 0.360
MOD_CK1_1 348 354 PF00069 0.411
MOD_CK1_1 40 46 PF00069 0.502
MOD_CK1_1 585 591 PF00069 0.388
MOD_CK1_1 599 605 PF00069 0.506
MOD_CK1_1 632 638 PF00069 0.582
MOD_CK1_1 645 651 PF00069 0.535
MOD_CK1_1 704 710 PF00069 0.321
MOD_CK1_1 74 80 PF00069 0.476
MOD_CK1_1 896 902 PF00069 0.702
MOD_CK1_1 995 1001 PF00069 0.286
MOD_CK2_1 105 111 PF00069 0.454
MOD_CK2_1 1127 1133 PF00069 0.298
MOD_CK2_1 1144 1150 PF00069 0.424
MOD_CK2_1 1234 1240 PF00069 0.346
MOD_CK2_1 1288 1294 PF00069 0.472
MOD_CK2_1 1418 1424 PF00069 0.432
MOD_CK2_1 1437 1443 PF00069 0.416
MOD_CK2_1 1534 1540 PF00069 0.557
MOD_CK2_1 1548 1554 PF00069 0.396
MOD_CK2_1 40 46 PF00069 0.595
MOD_CK2_1 552 558 PF00069 0.424
MOD_CK2_1 875 881 PF00069 0.384
MOD_CK2_1 934 940 PF00069 0.448
MOD_CK2_1 943 949 PF00069 0.416
MOD_Cter_Amidation 126 129 PF01082 0.481
MOD_GlcNHglycan 1004 1007 PF01048 0.426
MOD_GlcNHglycan 1102 1105 PF01048 0.320
MOD_GlcNHglycan 1127 1130 PF01048 0.331
MOD_GlcNHglycan 1180 1183 PF01048 0.239
MOD_GlcNHglycan 1288 1291 PF01048 0.463
MOD_GlcNHglycan 1307 1310 PF01048 0.588
MOD_GlcNHglycan 1356 1359 PF01048 0.319
MOD_GlcNHglycan 1421 1424 PF01048 0.263
MOD_GlcNHglycan 1474 1477 PF01048 0.406
MOD_GlcNHglycan 1500 1503 PF01048 0.408
MOD_GlcNHglycan 159 163 PF01048 0.292
MOD_GlcNHglycan 198 201 PF01048 0.650
MOD_GlcNHglycan 327 330 PF01048 0.350
MOD_GlcNHglycan 384 387 PF01048 0.330
MOD_GlcNHglycan 448 451 PF01048 0.341
MOD_GlcNHglycan 509 512 PF01048 0.253
MOD_GlcNHglycan 540 543 PF01048 0.281
MOD_GlcNHglycan 644 647 PF01048 0.614
MOD_GlcNHglycan 649 652 PF01048 0.405
MOD_GlcNHglycan 703 706 PF01048 0.320
MOD_GlcNHglycan 720 723 PF01048 0.249
MOD_GlcNHglycan 790 793 PF01048 0.312
MOD_GlcNHglycan 817 820 PF01048 0.374
MOD_GSK3_1 103 110 PF00069 0.476
MOD_GSK3_1 1053 1060 PF00069 0.249
MOD_GSK3_1 1077 1084 PF00069 0.324
MOD_GSK3_1 1127 1134 PF00069 0.335
MOD_GSK3_1 1136 1143 PF00069 0.326
MOD_GSK3_1 1198 1205 PF00069 0.369
MOD_GSK3_1 1226 1233 PF00069 0.297
MOD_GSK3_1 1234 1241 PF00069 0.313
MOD_GSK3_1 1284 1291 PF00069 0.425
MOD_GSK3_1 1354 1361 PF00069 0.345
MOD_GSK3_1 1544 1551 PF00069 0.435
MOD_GSK3_1 231 238 PF00069 0.418
MOD_GSK3_1 303 310 PF00069 0.315
MOD_GSK3_1 36 43 PF00069 0.559
MOD_GSK3_1 442 449 PF00069 0.408
MOD_GSK3_1 525 532 PF00069 0.398
MOD_GSK3_1 547 554 PF00069 0.313
MOD_GSK3_1 596 603 PF00069 0.462
MOD_GSK3_1 701 708 PF00069 0.302
MOD_GSK3_1 74 81 PF00069 0.618
MOD_GSK3_1 876 883 PF00069 0.438
MOD_GSK3_1 9 16 PF00069 0.543
MOD_GSK3_1 976 983 PF00069 0.354
MOD_GSK3_1 992 999 PF00069 0.262
MOD_N-GLC_1 1081 1086 PF02516 0.350
MOD_N-GLC_1 1186 1191 PF02516 0.346
MOD_N-GLC_1 1454 1459 PF02516 0.313
MOD_N-GLC_1 293 298 PF02516 0.388
MOD_N-GLC_1 740 745 PF02516 0.287
MOD_N-GLC_1 788 793 PF02516 0.309
MOD_NEK2_1 1002 1007 PF00069 0.322
MOD_NEK2_1 1046 1051 PF00069 0.278
MOD_NEK2_1 1057 1062 PF00069 0.305
MOD_NEK2_1 1077 1082 PF00069 0.191
MOD_NEK2_1 1149 1154 PF00069 0.365
MOD_NEK2_1 1230 1235 PF00069 0.311
MOD_NEK2_1 1238 1243 PF00069 0.299
MOD_NEK2_1 1362 1367 PF00069 0.257
MOD_NEK2_1 1406 1411 PF00069 0.342
MOD_NEK2_1 1418 1423 PF00069 0.348
MOD_NEK2_1 231 236 PF00069 0.379
MOD_NEK2_1 250 255 PF00069 0.379
MOD_NEK2_1 303 308 PF00069 0.324
MOD_NEK2_1 331 336 PF00069 0.361
MOD_NEK2_1 345 350 PF00069 0.388
MOD_NEK2_1 388 393 PF00069 0.354
MOD_NEK2_1 412 417 PF00069 0.333
MOD_NEK2_1 525 530 PF00069 0.407
MOD_NEK2_1 538 543 PF00069 0.336
MOD_NEK2_1 547 552 PF00069 0.333
MOD_NEK2_1 693 698 PF00069 0.373
MOD_NEK2_1 709 714 PF00069 0.294
MOD_NEK2_1 740 745 PF00069 0.309
MOD_NEK2_1 875 880 PF00069 0.449
MOD_NEK2_1 976 981 PF00069 0.294
MOD_NEK2_2 1053 1058 PF00069 0.399
MOD_PIKK_1 1219 1225 PF00454 0.368
MOD_PIKK_1 21 27 PF00454 0.485
MOD_PIKK_1 345 351 PF00454 0.219
MOD_PIKK_1 561 567 PF00454 0.499
MOD_PK_1 1136 1142 PF00069 0.430
MOD_PK_1 432 438 PF00069 0.209
MOD_PK_1 582 588 PF00069 0.351
MOD_PKA_1 128 134 PF00069 0.362
MOD_PKA_1 1472 1478 PF00069 0.413
MOD_PKA_1 442 448 PF00069 0.204
MOD_PKA_1 551 557 PF00069 0.329
MOD_PKA_2 1002 1008 PF00069 0.247
MOD_PKA_2 1053 1059 PF00069 0.370
MOD_PKA_2 1068 1074 PF00069 0.303
MOD_PKA_2 1131 1137 PF00069 0.352
MOD_PKA_2 118 124 PF00069 0.498
MOD_PKA_2 1218 1224 PF00069 0.299
MOD_PKA_2 1544 1550 PF00069 0.398
MOD_PKA_2 442 448 PF00069 0.422
MOD_PKA_2 529 535 PF00069 0.350
MOD_PKA_2 551 557 PF00069 0.315
MOD_PKA_2 599 605 PF00069 0.413
MOD_PKA_2 796 802 PF00069 0.330
MOD_PKA_2 896 902 PF00069 0.576
MOD_PKB_1 1435 1443 PF00069 0.286
MOD_Plk_1 1077 1083 PF00069 0.345
MOD_Plk_1 1149 1155 PF00069 0.350
MOD_Plk_1 1454 1460 PF00069 0.312
MOD_Plk_1 272 278 PF00069 0.411
MOD_Plk_1 293 299 PF00069 0.396
MOD_Plk_1 332 338 PF00069 0.218
MOD_Plk_1 355 361 PF00069 0.263
MOD_Plk_1 582 588 PF00069 0.368
MOD_Plk_1 726 732 PF00069 0.364
MOD_Plk_1 740 746 PF00069 0.241
MOD_Plk_1 880 886 PF00069 0.629
MOD_Plk_1 924 930 PF00069 0.560
MOD_Plk_4 1005 1011 PF00069 0.317
MOD_Plk_4 1053 1059 PF00069 0.254
MOD_Plk_4 1081 1087 PF00069 0.294
MOD_Plk_4 1295 1301 PF00069 0.451
MOD_Plk_4 1315 1321 PF00069 0.463
MOD_Plk_4 1358 1364 PF00069 0.319
MOD_Plk_4 1495 1501 PF00069 0.375
MOD_Plk_4 1504 1510 PF00069 0.318
MOD_Plk_4 1544 1550 PF00069 0.504
MOD_Plk_4 235 241 PF00069 0.300
MOD_Plk_4 303 309 PF00069 0.308
MOD_Plk_4 37 43 PF00069 0.511
MOD_Plk_4 407 413 PF00069 0.336
MOD_Plk_4 432 438 PF00069 0.374
MOD_Plk_4 494 500 PF00069 0.332
MOD_Plk_4 529 535 PF00069 0.329
MOD_Plk_4 552 558 PF00069 0.406
MOD_Plk_4 585 591 PF00069 0.325
MOD_Plk_4 693 699 PF00069 0.306
MOD_Plk_4 705 711 PF00069 0.256
MOD_Plk_4 84 90 PF00069 0.426
MOD_Plk_4 956 962 PF00069 0.312
MOD_Plk_4 992 998 PF00069 0.265
MOD_ProDKin_1 1021 1027 PF00069 0.283
MOD_ProDKin_1 1058 1064 PF00069 0.309
MOD_ProDKin_1 1140 1146 PF00069 0.321
MOD_ProDKin_1 1302 1308 PF00069 0.598
MOD_ProDKin_1 1534 1540 PF00069 0.467
MOD_ProDKin_1 193 199 PF00069 0.444
MOD_ProDKin_1 244 250 PF00069 0.477
MOD_ProDKin_1 492 498 PF00069 0.350
MOD_ProDKin_1 630 636 PF00069 0.581
MOD_ProDKin_1 7 13 PF00069 0.369
MOD_ProDKin_1 76 82 PF00069 0.546
MOD_SUMO_for_1 920 923 PF00179 0.653
MOD_SUMO_rev_2 1270 1280 PF00179 0.268
MOD_SUMO_rev_2 887 894 PF00179 0.555
MOD_SUMO_rev_2 913 922 PF00179 0.501
TRG_DiLeu_BaEn_1 1276 1281 PF01217 0.307
TRG_DiLeu_BaEn_1 14 19 PF01217 0.370
TRG_DiLeu_BaEn_1 940 945 PF01217 0.367
TRG_DiLeu_BaLyEn_6 534 539 PF01217 0.353
TRG_ENDOCYTIC_2 1009 1012 PF00928 0.284
TRG_ENDOCYTIC_2 1013 1016 PF00928 0.290
TRG_ENDOCYTIC_2 1032 1035 PF00928 0.416
TRG_ENDOCYTIC_2 1085 1088 PF00928 0.441
TRG_ENDOCYTIC_2 1120 1123 PF00928 0.353
TRG_ENDOCYTIC_2 1162 1165 PF00928 0.473
TRG_ENDOCYTIC_2 1180 1183 PF00928 0.259
TRG_ENDOCYTIC_2 1506 1509 PF00928 0.444
TRG_ENDOCYTIC_2 1521 1524 PF00928 0.254
TRG_ENDOCYTIC_2 321 324 PF00928 0.343
TRG_ENDOCYTIC_2 674 677 PF00928 0.308
TRG_ENDOCYTIC_2 857 860 PF00928 0.373
TRG_ENDOCYTIC_2 872 875 PF00928 0.338
TRG_ENDOCYTIC_2 94 97 PF00928 0.353
TRG_ER_diArg_1 1135 1137 PF00400 0.279
TRG_ER_diArg_1 1173 1175 PF00400 0.347
TRG_ER_diArg_1 1392 1394 PF00400 0.411
TRG_ER_diArg_1 142 144 PF00400 0.413
TRG_ER_diArg_1 191 193 PF00400 0.570
TRG_ER_diArg_1 611 614 PF00400 0.383
TRG_ER_diArg_1 833 836 PF00400 0.427
TRG_ER_diArg_1 863 866 PF00400 0.323
TRG_Pf-PMV_PEXEL_1 1040 1045 PF00026 0.345
TRG_Pf-PMV_PEXEL_1 128 133 PF00026 0.402
TRG_Pf-PMV_PEXEL_1 1390 1395 PF00026 0.310

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IGL0 Leptomonas seymouri 70% 100%
A0A0S4IYC2 Bodo saltans 42% 96%
A0A0S4JM70 Bodo saltans 40% 88%
A0A179H0T5 Purpureocillium lilacinum 24% 100%
A0A1U8QTJ9 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) 32% 100%
A0A1X0NHR8 Trypanosomatidae 46% 95%
A0A1X0NPP4 Trypanosomatidae 40% 90%
A0A3Q8IEG0 Leishmania donovani 99% 100%
A0A3Q8IFB0 Leishmania donovani 40% 100%
A0A3Q8III5 Leishmania donovani 39% 100%
A0A3S5ISD8 Trypanosoma rangeli 43% 99%
A0A3S7WXE4 Leishmania donovani 53% 100%
A0A3S7WXF3 Leishmania donovani 52% 100%
A0A3S7X4H7 Leishmania donovani 40% 94%
A0A422NY53 Trypanosoma rangeli 27% 100%
A4HCN5 Leishmania braziliensis 50% 100%
A4HCP0 Leishmania braziliensis 80% 100%
A4HCT5 Leishmania braziliensis 50% 100%
A4HJB0 Leishmania braziliensis 40% 100%
A4I059 Leishmania infantum 53% 100%
A4I060 Leishmania infantum 52% 99%
A4I065 Leishmania infantum 99% 100%
A4I6Q3 Leishmania infantum 40% 100%
A4I6Q4 Leishmania infantum 39% 100%
A4I6Q5 Leishmania infantum 38% 98%
C9ZM88 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 38% 89%
E9AW22 Leishmania mexicana (strain MHOM/GT/2001/U1103) 53% 100%
E9AW23 Leishmania mexicana (strain MHOM/GT/2001/U1103) 51% 100%
E9AW28 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
E9B1S5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 100%
O15440 Homo sapiens 31% 100%
P14772 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 100%
P21441 Leishmania tarentolae 84% 100%
P38735 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 99%
P53049 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 100%
P82451 Oryctolagus cuniculus 29% 100%
P91660 Drosophila melanogaster 30% 100%
Q09427 Cricetus cricetus 29% 99%
Q09428 Homo sapiens 29% 99%
Q09429 Rattus norvegicus 29% 99%
Q4Q6B9 Leishmania major 37% 87%
Q4Q6D4 Leishmania major 39% 99%
Q4Q6D5 Leishmania major 39% 96%
Q4Q6D6 Leishmania major 40% 100%
Q4QBE9 Leishmania major 93% 100%
Q4QBF3 Leishmania major 52% 100%
Q4QBF4 Leishmania major 53% 100%
Q54VJ0 Dictyostelium discoideum 28% 100%
Q6Y306 Rattus norvegicus 30% 100%
Q80WJ6 Mus musculus 30% 100%
Q8T6H3 Dictyostelium discoideum 27% 100%
Q96J65 Homo sapiens 30% 100%
Q9QYM0 Rattus norvegicus 31% 100%
Q9R1X5 Mus musculus 31% 100%
V5BK30 Trypanosoma cruzi 42% 97%
V5BKI5 Trypanosoma cruzi 26% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS