LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3Q8IAU5_LEIDO
TriTrypDb:
LdBPK_201030.1 , LdCL_200015000 , LDHU3_20.1270
Length:
891

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IAU5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IAU5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 556 560 PF00656 0.559
CLV_C14_Caspase3-7 621 625 PF00656 0.560
CLV_NRD_NRD_1 299 301 PF00675 0.665
CLV_NRD_NRD_1 358 360 PF00675 0.676
CLV_NRD_NRD_1 40 42 PF00675 0.617
CLV_NRD_NRD_1 545 547 PF00675 0.699
CLV_NRD_NRD_1 754 756 PF00675 0.596
CLV_PCSK_KEX2_1 147 149 PF00082 0.695
CLV_PCSK_KEX2_1 299 301 PF00082 0.650
CLV_PCSK_KEX2_1 358 360 PF00082 0.676
CLV_PCSK_KEX2_1 40 42 PF00082 0.617
CLV_PCSK_KEX2_1 545 547 PF00082 0.597
CLV_PCSK_KEX2_1 754 756 PF00082 0.598
CLV_PCSK_PC1ET2_1 147 149 PF00082 0.622
CLV_PCSK_PC7_1 36 42 PF00082 0.624
CLV_PCSK_PC7_1 750 756 PF00082 0.586
CLV_PCSK_SKI1_1 165 169 PF00082 0.668
CLV_PCSK_SKI1_1 638 642 PF00082 0.645
CLV_PCSK_SKI1_1 739 743 PF00082 0.654
DEG_APCC_DBOX_1 298 306 PF00400 0.626
DEG_COP1_1 533 540 PF00400 0.553
DEG_Kelch_Keap1_1 770 775 PF01344 0.665
DEG_SCF_FBW7_1 719 726 PF00400 0.594
DEG_SPOP_SBC_1 325 329 PF00917 0.671
DEG_SPOP_SBC_1 368 372 PF00917 0.567
DEG_SPOP_SBC_1 876 880 PF00917 0.630
DOC_CKS1_1 274 279 PF01111 0.584
DOC_CKS1_1 730 735 PF01111 0.688
DOC_CYCLIN_RxL_1 162 172 PF00134 0.659
DOC_CYCLIN_RxL_1 866 879 PF00134 0.553
DOC_CYCLIN_yCln2_LP_2 305 311 PF00134 0.609
DOC_CYCLIN_yCln2_LP_2 644 650 PF00134 0.537
DOC_MAPK_gen_1 358 365 PF00069 0.569
DOC_MAPK_MEF2A_6 174 182 PF00069 0.637
DOC_PP1_RVXF_1 636 642 PF00149 0.640
DOC_PP2B_LxvP_1 136 139 PF13499 0.692
DOC_PP2B_LxvP_1 168 171 PF13499 0.641
DOC_PP2B_LxvP_1 305 308 PF13499 0.631
DOC_PP2B_LxvP_1 379 382 PF13499 0.606
DOC_PP2B_LxvP_1 873 876 PF13499 0.637
DOC_PP4_FxxP_1 193 196 PF00568 0.655
DOC_PP4_FxxP_1 220 223 PF00568 0.642
DOC_USP7_MATH_1 252 256 PF00917 0.650
DOC_USP7_MATH_1 267 271 PF00917 0.530
DOC_USP7_MATH_1 326 330 PF00917 0.657
DOC_USP7_MATH_1 346 350 PF00917 0.495
DOC_USP7_MATH_1 423 427 PF00917 0.734
DOC_USP7_MATH_1 428 432 PF00917 0.673
DOC_USP7_MATH_1 516 520 PF00917 0.541
DOC_USP7_MATH_1 551 555 PF00917 0.687
DOC_USP7_MATH_1 607 611 PF00917 0.572
DOC_USP7_MATH_1 659 663 PF00917 0.672
DOC_USP7_MATH_1 668 672 PF00917 0.620
DOC_USP7_MATH_1 682 686 PF00917 0.548
DOC_USP7_MATH_1 75 79 PF00917 0.659
DOC_USP7_MATH_1 763 767 PF00917 0.697
DOC_USP7_MATH_1 818 822 PF00917 0.659
DOC_USP7_MATH_1 832 836 PF00917 0.567
DOC_USP7_MATH_1 861 865 PF00917 0.667
DOC_USP7_MATH_1 876 880 PF00917 0.519
DOC_USP7_UBL2_3 569 573 PF12436 0.538
DOC_USP7_UBL2_3 830 834 PF12436 0.682
DOC_WW_Pin1_4 123 128 PF00397 0.600
DOC_WW_Pin1_4 204 209 PF00397 0.589
DOC_WW_Pin1_4 273 278 PF00397 0.688
DOC_WW_Pin1_4 303 308 PF00397 0.566
DOC_WW_Pin1_4 327 332 PF00397 0.687
DOC_WW_Pin1_4 371 376 PF00397 0.596
DOC_WW_Pin1_4 386 391 PF00397 0.600
DOC_WW_Pin1_4 398 403 PF00397 0.583
DOC_WW_Pin1_4 410 415 PF00397 0.570
DOC_WW_Pin1_4 531 536 PF00397 0.628
DOC_WW_Pin1_4 643 648 PF00397 0.655
DOC_WW_Pin1_4 661 666 PF00397 0.525
DOC_WW_Pin1_4 717 722 PF00397 0.688
DOC_WW_Pin1_4 729 734 PF00397 0.586
DOC_WW_Pin1_4 94 99 PF00397 0.664
LIG_14-3-3_CanoR_1 148 152 PF00244 0.662
LIG_14-3-3_CanoR_1 266 275 PF00244 0.659
LIG_14-3-3_CanoR_1 290 297 PF00244 0.596
LIG_14-3-3_CanoR_1 46 53 PF00244 0.647
LIG_14-3-3_CanoR_1 502 510 PF00244 0.611
LIG_14-3-3_CanoR_1 517 521 PF00244 0.485
LIG_14-3-3_CanoR_1 670 674 PF00244 0.663
LIG_14-3-3_CanoR_1 743 748 PF00244 0.663
LIG_14-3-3_CanoR_1 79 84 PF00244 0.701
LIG_14-3-3_CanoR_1 877 882 PF00244 0.685
LIG_BRCT_BRCA1_1 159 163 PF00533 0.663
LIG_BRCT_BRCA1_1 216 220 PF00533 0.665
LIG_EVH1_1 193 197 PF00568 0.657
LIG_FHA_1 100 106 PF00498 0.590
LIG_FHA_1 130 136 PF00498 0.578
LIG_FHA_1 2 8 PF00498 0.633
LIG_FHA_1 219 225 PF00498 0.588
LIG_FHA_1 263 269 PF00498 0.644
LIG_FHA_1 368 374 PF00498 0.665
LIG_FHA_1 394 400 PF00498 0.588
LIG_FHA_1 438 444 PF00498 0.674
LIG_FHA_1 532 538 PF00498 0.546
LIG_FHA_1 562 568 PF00498 0.584
LIG_FHA_1 634 640 PF00498 0.620
LIG_FHA_1 729 735 PF00498 0.616
LIG_FHA_1 817 823 PF00498 0.685
LIG_FHA_2 516 522 PF00498 0.637
LIG_FHA_2 616 622 PF00498 0.679
LIG_FHA_2 9 15 PF00498 0.648
LIG_LIR_Apic_2 190 196 PF02991 0.649
LIG_LIR_Apic_2 217 223 PF02991 0.638
LIG_LIR_Gen_1 496 505 PF02991 0.634
LIG_LIR_Gen_1 775 781 PF02991 0.611
LIG_LIR_Nem_3 23 29 PF02991 0.620
LIG_LIR_Nem_3 496 501 PF02991 0.630
LIG_LIR_Nem_3 775 780 PF02991 0.686
LIG_LIR_Nem_3 868 873 PF02991 0.677
LIG_MYND_1 303 307 PF01753 0.571
LIG_MYND_1 463 467 PF01753 0.670
LIG_PCNA_PIPBox_1 738 747 PF02747 0.556
LIG_PCNA_yPIPBox_3 738 750 PF02747 0.556
LIG_PTB_Apo_2 880 887 PF02174 0.618
LIG_SH2_CRK 745 749 PF00017 0.560
LIG_SH2_SRC 498 501 PF00017 0.633
LIG_SH3_1 191 197 PF00018 0.653
LIG_SH3_1 278 284 PF00018 0.585
LIG_SH3_2 665 670 PF14604 0.575
LIG_SH3_3 122 128 PF00018 0.672
LIG_SH3_3 136 142 PF00018 0.560
LIG_SH3_3 191 197 PF00018 0.681
LIG_SH3_3 199 205 PF00018 0.616
LIG_SH3_3 271 277 PF00018 0.653
LIG_SH3_3 278 284 PF00018 0.607
LIG_SH3_3 305 311 PF00018 0.632
LIG_SH3_3 385 391 PF00018 0.657
LIG_SH3_3 532 538 PF00018 0.561
LIG_SH3_3 601 607 PF00018 0.576
LIG_SH3_3 662 668 PF00018 0.604
LIG_SH3_3 727 733 PF00018 0.594
LIG_SUMO_SIM_par_1 102 108 PF11976 0.555
LIG_SUMO_SIM_par_1 166 172 PF11976 0.644
LIG_TRAF2_1 781 784 PF00917 0.668
LIG_TYR_ITSM 22 29 PF00017 0.651
LIG_WRC_WIRS_1 170 175 PF05994 0.647
MOD_CDK_SPK_2 273 278 PF00069 0.615
MOD_CDK_SPxxK_3 398 405 PF00069 0.649
MOD_CK1_1 121 127 PF00069 0.672
MOD_CK1_1 207 213 PF00069 0.688
MOD_CK1_1 238 244 PF00069 0.660
MOD_CK1_1 255 261 PF00069 0.513
MOD_CK1_1 293 299 PF00069 0.598
MOD_CK1_1 315 321 PF00069 0.617
MOD_CK1_1 327 333 PF00069 0.645
MOD_CK1_1 349 355 PF00069 0.670
MOD_CK1_1 437 443 PF00069 0.659
MOD_CK1_1 454 460 PF00069 0.520
MOD_CK1_1 539 545 PF00069 0.691
MOD_CK1_1 58 64 PF00069 0.581
MOD_CK1_1 584 590 PF00069 0.629
MOD_CK1_1 615 621 PF00069 0.771
MOD_CK1_1 724 730 PF00069 0.703
MOD_CK1_1 762 768 PF00069 0.695
MOD_CK1_1 770 776 PF00069 0.626
MOD_CK1_1 78 84 PF00069 0.641
MOD_CK1_1 803 809 PF00069 0.615
MOD_CK1_1 820 826 PF00069 0.616
MOD_CK1_1 855 861 PF00069 0.662
MOD_CK1_1 862 868 PF00069 0.610
MOD_CK1_1 94 100 PF00069 0.544
MOD_CK2_1 123 129 PF00069 0.600
MOD_CK2_1 237 243 PF00069 0.664
MOD_CK2_1 616 622 PF00069 0.685
MOD_CK2_1 668 674 PF00069 0.673
MOD_CK2_1 766 772 PF00069 0.692
MOD_CK2_1 8 14 PF00069 0.652
MOD_CK2_1 821 827 PF00069 0.601
MOD_CK2_1 862 868 PF00069 0.671
MOD_Cter_Amidation 145 148 PF01082 0.690
MOD_Cter_Amidation 297 300 PF01082 0.643
MOD_Cter_Amidation 356 359 PF01082 0.675
MOD_GlcNHglycan 120 123 PF01048 0.638
MOD_GlcNHglycan 237 240 PF01048 0.670
MOD_GlcNHglycan 254 257 PF01048 0.508
MOD_GlcNHglycan 260 263 PF01048 0.615
MOD_GlcNHglycan 285 288 PF01048 0.698
MOD_GlcNHglycan 292 295 PF01048 0.600
MOD_GlcNHglycan 348 351 PF01048 0.635
MOD_GlcNHglycan 355 358 PF01048 0.650
MOD_GlcNHglycan 360 363 PF01048 0.598
MOD_GlcNHglycan 425 428 PF01048 0.704
MOD_GlcNHglycan 453 456 PF01048 0.628
MOD_GlcNHglycan 480 483 PF01048 0.614
MOD_GlcNHglycan 493 496 PF01048 0.595
MOD_GlcNHglycan 503 506 PF01048 0.581
MOD_GlcNHglycan 586 589 PF01048 0.526
MOD_GlcNHglycan 593 596 PF01048 0.510
MOD_GlcNHglycan 61 64 PF01048 0.617
MOD_GlcNHglycan 615 618 PF01048 0.734
MOD_GlcNHglycan 761 764 PF01048 0.700
MOD_GlcNHglycan 769 772 PF01048 0.623
MOD_GlcNHglycan 8 11 PF01048 0.555
MOD_GlcNHglycan 805 808 PF01048 0.678
MOD_GlcNHglycan 81 84 PF01048 0.610
MOD_GlcNHglycan 812 815 PF01048 0.658
MOD_GlcNHglycan 853 857 PF01048 0.656
MOD_GSK3_1 157 164 PF00069 0.604
MOD_GSK3_1 169 176 PF00069 0.606
MOD_GSK3_1 2 9 PF00069 0.605
MOD_GSK3_1 200 207 PF00069 0.659
MOD_GSK3_1 214 221 PF00069 0.547
MOD_GSK3_1 251 258 PF00069 0.652
MOD_GSK3_1 289 296 PF00069 0.656
MOD_GSK3_1 320 327 PF00069 0.668
MOD_GSK3_1 345 352 PF00069 0.668
MOD_GSK3_1 363 370 PF00069 0.518
MOD_GSK3_1 435 442 PF00069 0.635
MOD_GSK3_1 55 62 PF00069 0.658
MOD_GSK3_1 607 614 PF00069 0.695
MOD_GSK3_1 657 664 PF00069 0.675
MOD_GSK3_1 717 724 PF00069 0.691
MOD_GSK3_1 75 82 PF00069 0.543
MOD_GSK3_1 755 762 PF00069 0.684
MOD_GSK3_1 763 770 PF00069 0.633
MOD_GSK3_1 810 817 PF00069 0.652
MOD_GSK3_1 851 858 PF00069 0.656
MOD_GSK3_1 882 889 PF00069 0.692
MOD_GSK3_1 92 99 PF00069 0.566
MOD_N-GLC_1 363 368 PF02516 0.642
MOD_N-GLC_1 429 434 PF02516 0.685
MOD_N-GLC_1 435 440 PF02516 0.614
MOD_N-GLC_1 478 483 PF02516 0.588
MOD_N-GLC_1 58 63 PF02516 0.579
MOD_N-GLC_1 591 596 PF02516 0.560
MOD_N-GLC_1 862 867 PF02516 0.671
MOD_N-GLC_1 882 887 PF02516 0.619
MOD_N-GLC_2 488 490 PF02516 0.553
MOD_NEK2_1 1 6 PF00069 0.646
MOD_NEK2_1 180 185 PF00069 0.641
MOD_NEK2_1 19 24 PF00069 0.489
MOD_NEK2_1 213 218 PF00069 0.623
MOD_NEK2_1 332 337 PF00069 0.714
MOD_NEK2_1 363 368 PF00069 0.664
MOD_NEK2_1 369 374 PF00069 0.618
MOD_NEK2_1 493 498 PF00069 0.616
MOD_NEK2_1 734 739 PF00069 0.592
MOD_NEK2_1 8 13 PF00069 0.586
MOD_NEK2_1 851 856 PF00069 0.625
MOD_NEK2_1 859 864 PF00069 0.647
MOD_NEK2_1 886 891 PF00069 0.668
MOD_NEK2_2 586 591 PF00069 0.542
MOD_PIKK_1 157 163 PF00454 0.668
MOD_PIKK_1 173 179 PF00454 0.493
MOD_PIKK_1 214 220 PF00454 0.667
MOD_PIKK_1 333 339 PF00454 0.580
MOD_PIKK_1 393 399 PF00454 0.604
MOD_PIKK_1 429 435 PF00454 0.654
MOD_PIKK_1 734 740 PF00454 0.662
MOD_PK_1 743 749 PF00069 0.662
MOD_PK_1 843 849 PF00069 0.674
MOD_PKA_1 147 153 PF00069 0.694
MOD_PKA_1 358 364 PF00069 0.671
MOD_PKA_2 147 153 PF00069 0.691
MOD_PKA_2 173 179 PF00069 0.633
MOD_PKA_2 218 224 PF00069 0.574
MOD_PKA_2 289 295 PF00069 0.679
MOD_PKA_2 350 356 PF00069 0.754
MOD_PKA_2 358 364 PF00069 0.707
MOD_PKA_2 45 51 PF00069 0.646
MOD_PKA_2 501 507 PF00069 0.626
MOD_PKA_2 516 522 PF00069 0.482
MOD_PKA_2 628 634 PF00069 0.658
MOD_PKA_2 669 675 PF00069 0.660
MOD_PKA_2 775 781 PF00069 0.551
MOD_PKA_2 78 84 PF00069 0.699
MOD_PKA_2 851 857 PF00069 0.568
MOD_PKA_2 876 882 PF00069 0.630
MOD_Plk_1 435 441 PF00069 0.633
MOD_Plk_1 843 849 PF00069 0.674
MOD_Plk_1 882 888 PF00069 0.620
MOD_Plk_2-3 129 135 PF00069 0.574
MOD_Plk_4 100 106 PF00069 0.662
MOD_Plk_4 439 445 PF00069 0.777
MOD_Plk_4 562 568 PF00069 0.555
MOD_Plk_4 586 592 PF00069 0.544
MOD_Plk_4 743 749 PF00069 0.662
MOD_Plk_4 855 861 PF00069 0.633
MOD_ProDKin_1 123 129 PF00069 0.600
MOD_ProDKin_1 204 210 PF00069 0.589
MOD_ProDKin_1 273 279 PF00069 0.686
MOD_ProDKin_1 303 309 PF00069 0.569
MOD_ProDKin_1 327 333 PF00069 0.689
MOD_ProDKin_1 371 377 PF00069 0.597
MOD_ProDKin_1 386 392 PF00069 0.600
MOD_ProDKin_1 398 404 PF00069 0.581
MOD_ProDKin_1 410 416 PF00069 0.567
MOD_ProDKin_1 531 537 PF00069 0.631
MOD_ProDKin_1 643 649 PF00069 0.654
MOD_ProDKin_1 661 667 PF00069 0.522
MOD_ProDKin_1 717 723 PF00069 0.689
MOD_ProDKin_1 729 735 PF00069 0.583
MOD_ProDKin_1 94 100 PF00069 0.663
MOD_SUMO_for_1 690 693 PF00179 0.590
MOD_SUMO_for_1 781 784 PF00179 0.698
TRG_DiLeu_BaEn_4 14 20 PF01217 0.650
TRG_DiLeu_BaLyEn_6 229 234 PF01217 0.575
TRG_DiLeu_BaLyEn_6 300 305 PF01217 0.583
TRG_ENDOCYTIC_2 26 29 PF00928 0.651
TRG_ENDOCYTIC_2 498 501 PF00928 0.633
TRG_ENDOCYTIC_2 745 748 PF00928 0.590
TRG_ER_diArg_1 39 41 PF00400 0.626
TRG_Pf-PMV_PEXEL_1 165 169 PF00026 0.668

Homologs

Protein Taxonomy Sequence identity Coverage
A4HYU3 Leishmania infantum 94% 100%
E9AUP0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 100%
Q4QCU4 Leishmania major 81% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS