RNA-binding_protein_putative/GeneDB:LmjF.17.0550

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8IAN2_LEIDO

TriTrypDb:

LdBPK_170610.1 , LdCL_170011500 , LDHU3_17.0910

Length:

301

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8IAN2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8IAN2

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	10
GO:0003723	RNA binding	4	10
GO:0005488	binding	1	10
GO:0097159	organic cyclic compound binding	2	10
GO:1901363	heterocyclic compound binding	2	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	125	127	PF00675	0.611
CLV_NRD_NRD_1	131	133	PF00675	0.622
CLV_NRD_NRD_1	146	148	PF00675	0.740
CLV_PCSK_FUR_1	92	96	PF00082	0.642
CLV_PCSK_KEX2_1	131	133	PF00082	0.660
CLV_PCSK_KEX2_1	146	148	PF00082	0.617
CLV_PCSK_KEX2_1	41	43	PF00082	0.581
CLV_PCSK_KEX2_1	94	96	PF00082	0.757
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.550
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.739
CLV_PCSK_SKI1_1	42	46	PF00082	0.459
DEG_APCC_DBOX_1	249	257	PF00400	0.479
DEG_APCC_DBOX_1	60	68	PF00400	0.483
DEG_COP1_1	130	139	PF00400	0.552
DEG_Nend_UBRbox_2	1	3	PF02207	0.469
DEG_SPOP_SBC_1	76	80	PF00917	0.551
DOC_CYCLIN_yClb3_PxF_3	210	216	PF00134	0.609
DOC_MAPK_gen_1	41	49	PF00069	0.412
DOC_MAPK_MEF2A_6	250	259	PF00069	0.542
DOC_MAPK_MEF2A_6	290	299	PF00069	0.438
DOC_MAPK_MEF2A_6	42	51	PF00069	0.394
DOC_PP2B_LxvP_1	180	183	PF13499	0.565
DOC_PP2B_LxvP_1	197	200	PF13499	0.578
DOC_PP4_FxxP_1	186	189	PF00568	0.699
DOC_PP4_FxxP_1	259	262	PF00568	0.542
DOC_USP7_MATH_1	165	169	PF00917	0.574
DOC_USP7_MATH_1	30	34	PF00917	0.468
DOC_USP7_UBL2_3	37	41	PF12436	0.513
DOC_WW_Pin1_4	77	82	PF00397	0.726
LIG_14-3-3_CanoR_1	11	18	PF00244	0.544
LIG_BIR_III_2	65	69	PF00653	0.545
LIG_EVH1_2	182	186	PF00568	0.561
LIG_FHA_1	286	292	PF00498	0.471
LIG_FHA_1	44	50	PF00498	0.459
LIG_FHA_2	138	144	PF00498	0.558
LIG_FHA_2	19	25	PF00498	0.522
LIG_FHA_2	48	54	PF00498	0.518
LIG_FHA_2	77	83	PF00498	0.637
LIG_LIR_Gen_1	113	120	PF02991	0.671
LIG_LIR_Gen_1	12	22	PF02991	0.445
LIG_LIR_Gen_1	237	246	PF02991	0.519
LIG_LIR_Gen_1	45	56	PF02991	0.400
LIG_LIR_Nem_3	113	117	PF02991	0.668
LIG_LIR_Nem_3	12	18	PF02991	0.455
LIG_LIR_Nem_3	237	242	PF02991	0.459
LIG_LIR_Nem_3	24	28	PF02991	0.410
LIG_LIR_Nem_3	45	51	PF02991	0.384
LIG_MYND_1	211	215	PF01753	0.595
LIG_PROFILIN_1	199	205	PF00235	0.501
LIG_PTB_Apo_2	222	229	PF02174	0.479
LIG_SH2_STAT3	120	123	PF00017	0.659
LIG_SH2_STAT5	234	237	PF00017	0.519
LIG_SH3_2	207	212	PF14604	0.577
LIG_SH3_3	196	202	PF00018	0.741
LIG_SH3_3	203	209	PF00018	0.523
LIG_SH3_3	286	292	PF00018	0.391
LIG_SH3_CIN85_PxpxPR_1	207	212	PF14604	0.577
LIG_SUMO_SIM_anti_2	252	257	PF11976	0.542
LIG_SUMO_SIM_par_1	279	286	PF11976	0.549
LIG_TRAF2_1	81	84	PF00917	0.752
LIG_WRC_WIRS_1	31	36	PF05994	0.555
LIG_WRC_WIRS_1	48	53	PF05994	0.512
LIG_WW_3	209	213	PF00397	0.599
MOD_CK1_1	285	291	PF00069	0.425
MOD_CK1_1	9	15	PF00069	0.537
MOD_CK1_1	93	99	PF00069	0.732
MOD_CK2_1	13	19	PF00069	0.537
MOD_CK2_1	137	143	PF00069	0.555
MOD_CK2_1	30	36	PF00069	0.568
MOD_CK2_1	76	82	PF00069	0.577
MOD_GlcNHglycan	15	18	PF01048	0.559
MOD_GlcNHglycan	239	242	PF01048	0.318
MOD_GlcNHglycan	285	288	PF01048	0.414
MOD_GlcNHglycan	88	91	PF01048	0.698
MOD_GSK3_1	102	109	PF00069	0.611
MOD_GSK3_1	137	144	PF00069	0.721
MOD_GSK3_1	43	50	PF00069	0.512
MOD_GSK3_1	5	12	PF00069	0.520
MOD_GSK3_1	72	79	PF00069	0.644
MOD_GSK3_1	84	91	PF00069	0.722
MOD_N-GLC_1	159	164	PF02516	0.719
MOD_N-GLC_1	272	277	PF02516	0.340
MOD_NEK2_1	228	233	PF00069	0.542
MOD_NEK2_1	272	277	PF00069	0.540
MOD_NEK2_1	5	10	PF00069	0.510
MOD_NEK2_2	30	35	PF00069	0.463
MOD_PIKK_1	93	99	PF00454	0.757
MOD_PKA_2	10	16	PF00069	0.543
MOD_PKA_2	130	136	PF00069	0.646
MOD_Plk_1	18	24	PF00069	0.469
MOD_Plk_1	42	48	PF00069	0.480
MOD_Plk_4	43	49	PF00069	0.460
MOD_ProDKin_1	77	83	PF00069	0.726
MOD_SUMO_rev_2	105	110	PF00179	0.722
TRG_ER_diArg_1	146	149	PF00400	0.733
TRG_ER_diArg_1	172	175	PF00400	0.698
TRG_Pf-PMV_PEXEL_1	233	237	PF00026	0.296

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZY5	Leptomonas seymouri	51%	100%
A0A1X0P0T6	Trypanosomatidae	36%	100%
A0A3R7MFN4	Trypanosoma rangeli	35%	100%
A4H8Z8	Leishmania braziliensis	79%	100%
A4HXC9	Leishmania infantum	98%	98%
E9AR24	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4QED9	Leishmania major	92%	99%
V5AZY6	Trypanosoma cruzi	36%	100%