Degradation arginine-rich protein for mis-folding, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Degradation arginine-rich protein for mis-folding, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8I9L2_LEIDO

TriTrypDb:

LdCL_170005100 , LDHU3_17.0030

Length:

164

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 2, no: 1
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I9L2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I9L2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	126	128	PF00675	0.623
CLV_NRD_NRD_1	41	43	PF00675	0.560
CLV_NRD_NRD_1	97	99	PF00675	0.520
CLV_PCSK_KEX2_1	126	128	PF00082	0.623
CLV_PCSK_KEX2_1	41	43	PF00082	0.560
CLV_PCSK_KEX2_1	97	99	PF00082	0.520
CLV_PCSK_SKI1_1	127	131	PF00082	0.588
CLV_PCSK_SKI1_1	53	57	PF00082	0.556
DEG_SPOP_SBC_1	60	64	PF00917	0.589
DOC_MAPK_MEF2A_6	24	31	PF00069	0.619
DOC_MAPK_RevD_3	27	42	PF00069	0.605
DOC_PP1_RVXF_1	114	120	PF00149	0.526
DOC_USP7_MATH_1	2	6	PF00917	0.548
DOC_USP7_MATH_1	60	64	PF00917	0.557
DOC_USP7_MATH_1	65	69	PF00917	0.452
DOC_USP7_UBL2_3	78	82	PF12436	0.320
DOC_WW_Pin1_4	61	66	PF00397	0.584
LIG_14-3-3_CanoR_1	126	132	PF00244	0.624
LIG_14-3-3_CanoR_1	24	28	PF00244	0.600
LIG_FHA_1	140	146	PF00498	0.523
LIG_FHA_1	34	40	PF00498	0.609
LIG_FHA_1	54	60	PF00498	0.356
LIG_FHA_2	110	116	PF00498	0.497
LIG_FHA_2	120	126	PF00498	0.564
LIG_FHA_2	131	137	PF00498	0.586
LIG_LIR_Gen_1	156	164	PF02991	0.578
LIG_LIR_Nem_3	156	161	PF02991	0.624
LIG_PTB_Apo_2	134	141	PF02174	0.646
LIG_SH2_CRK	158	162	PF00017	0.563
LIG_SH2_STAT3	105	108	PF00017	0.306
LIG_SH2_STAT5	158	161	PF00017	0.560
LIG_TYR_ITSM	154	161	PF00017	0.571
MOD_CK1_1	61	67	PF00069	0.583
MOD_CK1_1	74	80	PF00069	0.306
MOD_CK2_1	109	115	PF00069	0.496
MOD_CK2_1	130	136	PF00069	0.590
MOD_CK2_1	43	49	PF00069	0.702
MOD_CK2_1	73	79	PF00069	0.309
MOD_GlcNHglycan	18	21	PF01048	0.578
MOD_GSK3_1	139	146	PF00069	0.580
MOD_GSK3_1	61	68	PF00069	0.515
MOD_LATS_1	71	77	PF00433	0.320
MOD_N-GLC_1	153	158	PF02516	0.538
MOD_N-GLC_1	65	70	PF02516	0.606
MOD_NEK2_1	145	150	PF00069	0.555
MOD_NEK2_1	153	158	PF00069	0.545
MOD_PKA_2	23	29	PF00069	0.656
MOD_PKA_2	86	92	PF00069	0.306
MOD_Plk_1	153	159	PF00069	0.533
MOD_Plk_1	33	39	PF00069	0.579
MOD_Plk_1	65	71	PF00069	0.551
MOD_Plk_4	153	159	PF00069	0.554
MOD_Plk_4	23	29	PF00069	0.547
MOD_Plk_4	33	39	PF00069	0.579
MOD_ProDKin_1	61	67	PF00069	0.571
TRG_DiLeu_BaEn_1	34	39	PF01217	0.522
TRG_DiLeu_BaEn_1	96	101	PF01217	0.265
TRG_DiLeu_BaEn_2	135	141	PF01217	0.596
TRG_DiLeu_BaLyEn_6	124	129	PF01217	0.598
TRG_ENDOCYTIC_2	158	161	PF00928	0.560
TRG_ER_diArg_1	126	128	PF00400	0.623
TRG_Pf-PMV_PEXEL_1	98	102	PF00026	0.520

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB57	Leptomonas seymouri	63%	100%
C9ZTT1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%