Actin-like protein, putative

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

actin-like protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8I9L1_LEIDO

TriTrypDb:

LdBPK_130840.1 , LdCL_130013800 , LDHU3_13.1050

Length:

483

Annotations

Annotations by Jardim et al.

Structural Proteins, actin-like

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005884	actin filament	6	1
GO:0005930	axoneme	2	1
GO:0043226	organelle	2	9
GO:0099080	supramolecular complex	2	1
GO:0099081	supramolecular polymer	3	1
GO:0099512	supramolecular fiber	4	1
GO:0099513	polymeric cytoskeletal fiber	5	1
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

A0A3Q8I9L1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I9L1

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005198	structural molecule activity	1	1
GO:0005200	structural constituent of cytoskeleton	2	1
GO:0098918	structural constituent of synapse	2	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	3	1
GO:0099186	structural constituent of postsynapse	3	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	256	258	PF00675	0.370
CLV_NRD_NRD_1	466	468	PF00675	0.340
CLV_PCSK_KEX2_1	256	258	PF00082	0.370
CLV_PCSK_SKI1_1	159	163	PF00082	0.327
CLV_PCSK_SKI1_1	175	179	PF00082	0.205
CLV_PCSK_SKI1_1	300	304	PF00082	0.217
DEG_MDM2_SWIB_1	77	84	PF02201	0.540
DEG_Nend_UBRbox_2	1	3	PF02207	0.657
DEG_SCF_TRCP1_1	156	162	PF00400	0.469
DOC_CKS1_1	235	240	PF01111	0.540

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P696	Leptomonas seymouri	27%	100%
A0A0N0P8M2	Leptomonas seymouri	72%	100%
A0A0N1I659	Leptomonas seymouri	26%	97%
A0A0N1IM09	Leptomonas seymouri	24%	100%
A0A1X0NJ12	Trypanosomatidae	23%	100%
A0A3Q8IEK0	Leishmania donovani	24%	100%
A0A3Q8IJ53	Leishmania donovani	26%	93%
A0A422NGD7	Trypanosoma rangeli	53%	100%
A0A422NI92	Trypanosoma rangeli	26%	100%
A0A422NRB8	Trypanosoma rangeli	26%	100%

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