Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8I9J1_LEIDO

TriTrypDb:

LdBPK_130190.1 , LdCL_130006900 , LDHU3_13.0240

Length:

248

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I9J1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I9J1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	120	122	PF00675	0.609
CLV_NRD_NRD_1	134	136	PF00675	0.552
CLV_NRD_NRD_1	139	141	PF00675	0.562
CLV_NRD_NRD_1	208	210	PF00675	0.613
CLV_NRD_NRD_1	8	10	PF00675	0.634
CLV_PCSK_KEX2_1	139	141	PF00082	0.551
CLV_PCSK_KEX2_1	66	68	PF00082	0.525
CLV_PCSK_KEX2_1	8	10	PF00082	0.635
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.628
CLV_PCSK_PC7_1	135	141	PF00082	0.533
CLV_PCSK_SKI1_1	121	125	PF00082	0.666
CLV_PCSK_SKI1_1	63	67	PF00082	0.597
CLV_PCSK_SKI1_1	76	80	PF00082	0.539
DEG_Nend_Nbox_1	1	3	PF02207	0.626
DOC_ANK_TNKS_1	177	184	PF00023	0.496
DOC_CKS1_1	54	59	PF01111	0.533
DOC_CKS1_1	82	87	PF01111	0.604
DOC_MAPK_MEF2A_6	178	186	PF00069	0.468
DOC_USP7_MATH_1	15	19	PF00917	0.714
DOC_USP7_MATH_1	156	160	PF00917	0.666
DOC_USP7_UBL2_3	59	63	PF12436	0.583
DOC_WW_Pin1_4	152	157	PF00397	0.689
DOC_WW_Pin1_4	191	196	PF00397	0.522
DOC_WW_Pin1_4	53	58	PF00397	0.713
DOC_WW_Pin1_4	81	86	PF00397	0.660
LIG_14-3-3_CanoR_1	121	127	PF00244	0.577
LIG_14-3-3_CanoR_1	28	36	PF00244	0.511
LIG_14-3-3_CanoR_1	51	57	PF00244	0.683
LIG_14-3-3_CanoR_1	8	16	PF00244	0.618
LIG_APCC_ABBA_1	230	235	PF00400	0.510
LIG_DCNL_PONY_1	1	4	PF03556	0.620
LIG_EVH1_1	81	85	PF00568	0.601
LIG_FHA_1	1	7	PF00498	0.567
LIG_FHA_1	203	209	PF00498	0.481
LIG_LIR_Gen_1	159	167	PF02991	0.611
LIG_LIR_Nem_3	125	129	PF02991	0.553
LIG_LIR_Nem_3	130	134	PF02991	0.548
LIG_LIR_Nem_3	154	160	PF02991	0.636
LIG_LIR_Nem_3	18	24	PF02991	0.532
LIG_LIR_Nem_3	64	68	PF02991	0.514
LIG_PTB_Apo_2	125	132	PF02174	0.515
LIG_SH2_CRK	201	205	PF00017	0.449
LIG_SH2_GRB2like	160	163	PF00017	0.616
LIG_SH2_NCK_1	160	164	PF00017	0.613
LIG_SH2_NCK_1	69	73	PF00017	0.604
LIG_SH2_STAT5	236	239	PF00017	0.614
LIG_SH2_STAT5	24	27	PF00017	0.644
LIG_SH2_STAT5	245	248	PF00017	0.574
LIG_SH2_STAT5	36	39	PF00017	0.556
LIG_SH3_3	51	57	PF00018	0.722
LIG_SH3_3	79	85	PF00018	0.598
LIG_SUMO_SIM_anti_2	3	8	PF11976	0.557
LIG_TYR_ITIM	124	129	PF00017	0.578
MOD_CDK_SPxK_1	53	59	PF00069	0.608
MOD_CK1_1	149	155	PF00069	0.746
MOD_CK1_1	171	177	PF00069	0.689
MOD_CK1_1	55	61	PF00069	0.657
MOD_CK2_1	105	111	PF00069	0.444
MOD_CK2_1	158	164	PF00069	0.612
MOD_CK2_1	190	196	PF00069	0.611
MOD_GlcNHglycan	17	20	PF01048	0.608
MOD_GlcNHglycan	170	173	PF01048	0.688
MOD_GlcNHglycan	220	223	PF01048	0.518
MOD_GlcNHglycan	240	243	PF01048	0.470
MOD_GlcNHglycan	31	34	PF01048	0.525
MOD_GlcNHglycan	47	50	PF01048	0.706
MOD_GSK3_1	145	152	PF00069	0.710
MOD_GSK3_1	72	79	PF00069	0.587
MOD_N-GLC_1	218	223	PF02516	0.494
MOD_N-GLC_1	29	34	PF02516	0.634
MOD_NEK2_1	2	7	PF00069	0.606
MOD_NEK2_2	23	28	PF00069	0.473
MOD_OFUCOSY	103	109	PF10250	0.548
MOD_PKA_1	135	141	PF00069	0.650
MOD_PKA_2	7	13	PF00069	0.628
MOD_PKB_1	74	82	PF00069	0.626
MOD_Plk_1	76	82	PF00069	0.566
MOD_Plk_4	2	8	PF00069	0.642
MOD_ProDKin_1	152	158	PF00069	0.688
MOD_ProDKin_1	191	197	PF00069	0.515
MOD_ProDKin_1	53	59	PF00069	0.715
MOD_ProDKin_1	81	87	PF00069	0.657
MOD_SUMO_rev_2	114	124	PF00179	0.571
MOD_SUMO_rev_2	58	68	PF00179	0.567
TRG_ENDOCYTIC_2	126	129	PF00928	0.582
TRG_ENDOCYTIC_2	160	163	PF00928	0.616
TRG_ENDOCYTIC_2	201	204	PF00928	0.453
TRG_ENDOCYTIC_2	24	27	PF00928	0.473
TRG_ENDOCYTIC_2	69	72	PF00928	0.599
TRG_ER_diArg_1	7	9	PF00400	0.639

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ69	Leptomonas seymouri	59%	100%
A4H726	Leishmania braziliensis	78%	100%
A4HVF5	Leishmania infantum	97%	100%
E9AP53	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QGD5	Leishmania major	94%	100%