Cyclic nucleotide-binding domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3Q8I9H4_LEIDO

TriTrypDb:

LdCL_120018000 , LDHU3_12.1270

Length:

218

Annotations

LeishMANIAdb annotations

This is a highly disordered Cys-rich prote8in with spurious hydrophobic segments. Very low conservation.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I9H4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I9H4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	33	37	PF00656	0.470
CLV_NRD_NRD_1	136	138	PF00675	0.508
CLV_NRD_NRD_1	187	189	PF00675	0.495
CLV_NRD_NRD_1	28	30	PF00675	0.487
CLV_NRD_NRD_1	4	6	PF00675	0.491
CLV_PCSK_FUR_1	183	187	PF00082	0.501
CLV_PCSK_KEX2_1	136	138	PF00082	0.508
CLV_PCSK_KEX2_1	185	187	PF00082	0.499
CLV_PCSK_KEX2_1	28	30	PF00082	0.487
CLV_PCSK_KEX2_1	4	6	PF00082	0.491
CLV_PCSK_PC7_1	181	187	PF00082	0.499
DOC_PP2B_LxvP_1	126	129	PF13499	0.474
DOC_USP7_MATH_1	121	125	PF00917	0.473
DOC_USP7_MATH_1	41	45	PF00917	0.446
DOC_USP7_MATH_1	70	74	PF00917	0.373
DOC_WW_Pin1_4	143	148	PF00397	0.460
DOC_WW_Pin1_4	42	47	PF00397	0.430
DOC_WW_Pin1_4	6	11	PF00397	0.478
DOC_WW_Pin1_4	81	86	PF00397	0.383
LIG_14-3-3_CanoR_1	105	111	PF00244	0.401
LIG_14-3-3_CanoR_1	145	154	PF00244	0.436
LIG_BIR_II_1	1	5	PF00653	0.490
LIG_CtBP_PxDLS_1	85	89	PF00389	0.382
LIG_eIF4E_1	42	48	PF01652	0.422
LIG_EVH1_2	56	60	PF00568	0.416
LIG_FHA_1	107	113	PF00498	0.415
LIG_FHA_1	153	159	PF00498	0.425
LIG_FHA_1	194	200	PF00498	0.503
LIG_FHA_2	31	37	PF00498	0.472
LIG_FHA_2	82	88	PF00498	0.381
LIG_LIR_Apic_2	142	147	PF02991	0.457
LIG_LIR_Gen_1	87	97	PF02991	0.378
LIG_LIR_Nem_3	87	93	PF02991	0.379
LIG_NRBOX	92	98	PF00104	0.381
LIG_OCRL_FandH_1	89	101	PF00620	0.381
LIG_Pex14_2	60	64	PF04695	0.402
LIG_SH3_3	11	17	PF00018	0.480
LIG_SH3_3	125	131	PF00018	0.477
LIG_SH3_CIN85_PxpxPR_1	189	194	PF14604	0.494
LIG_SUMO_SIM_par_1	84	89	PF11976	0.382
MOD_CDK_SPK_2	143	148	PF00069	0.460
MOD_CDK_SPK_2	8	13	PF00069	0.476
MOD_CDK_SPxxK_3	6	13	PF00069	0.476
MOD_CK1_1	146	152	PF00069	0.436
MOD_CK1_1	159	165	PF00069	0.449
MOD_Cter_Amidation	183	186	PF01082	0.501
MOD_GlcNHglycan	148	151	PF01048	0.437
MOD_GlcNHglycan	157	161	PF01048	0.437
MOD_GlcNHglycan	23	26	PF01048	0.452
MOD_GlcNHglycan	57	60	PF01048	0.428
MOD_GlcNHglycan	90	93	PF01048	0.376
MOD_GSK3_1	152	159	PF00069	0.422
MOD_NEK2_1	60	65	PF00069	0.405
MOD_NEK2_1	86	91	PF00069	0.374
MOD_PIKK_1	121	127	PF00454	0.477
MOD_PIKK_1	164	170	PF00454	0.473
MOD_PKA_2	152	158	PF00069	0.421
MOD_PKA_2	193	199	PF00069	0.500
MOD_Plk_1	156	162	PF00069	0.435
MOD_Plk_1	164	170	PF00069	0.473
MOD_Plk_1	86	92	PF00069	0.375
MOD_ProDKin_1	143	149	PF00069	0.451
MOD_ProDKin_1	42	48	PF00069	0.422
MOD_ProDKin_1	6	12	PF00069	0.475
MOD_ProDKin_1	81	87	PF00069	0.383
TRG_DiLeu_BaLyEn_6	128	133	PF01217	0.478
TRG_DiLeu_BaLyEn_6	43	48	PF01217	0.414
TRG_ER_diArg_1	183	186	PF00400	0.501
TRG_ER_diArg_1	187	189	PF00400	0.495
TRG_ER_diArg_1	214	217	PF00400	0.516
TRG_ER_diArg_1	27	29	PF00400	0.490
TRG_ER_diArg_1	3	5	PF00400	0.496