SNARE associated Golgi protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SNARE associated Golgi protein, putative

Species:

Leishmania donovani

UniProt:

A0A3Q8I9D7_LEIDO

TriTrypDb:

LdBPK_120810.1 , LdCL_120020200 , LDHU3_12.1610

Length:

329

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	11
GO:0110165	cellular anatomical entity	1	11
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A0A3Q8I9D7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I9D7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	179	183	PF00656	0.446
CLV_C14_Caspase3-7	299	303	PF00656	0.641
CLV_MEL_PAP_1	251	257	PF00089	0.414
CLV_NRD_NRD_1	299	301	PF00675	0.425
CLV_PCSK_KEX2_1	268	270	PF00082	0.659
CLV_PCSK_PC1ET2_1	268	270	PF00082	0.659
CLV_PCSK_SKI1_1	189	193	PF00082	0.242
CLV_PCSK_SKI1_1	269	273	PF00082	0.513
CLV_PCSK_SKI1_1	32	36	PF00082	0.467
CLV_PCSK_SKI1_1	52	56	PF00082	0.496
DEG_APCC_DBOX_1	51	59	PF00400	0.336
DEG_SCF_FBW7_1	270	276	PF00400	0.333
DOC_CKS1_1	270	275	PF01111	0.383
DOC_MAPK_gen_1	49	59	PF00069	0.311
DOC_MAPK_HePTP_8	29	41	PF00069	0.253
DOC_MAPK_MEF2A_6	202	211	PF00069	0.460
DOC_MAPK_MEF2A_6	32	41	PF00069	0.291
DOC_MAPK_MEF2A_6	52	61	PF00069	0.242
DOC_PP2B_LxvP_1	230	233	PF13499	0.333
DOC_PP2B_LxvP_1	4	7	PF13499	0.314
DOC_PP4_FxxP_1	130	133	PF00568	0.331
DOC_USP7_MATH_1	9	13	PF00917	0.402
DOC_USP7_UBL2_3	103	107	PF12436	0.492
DOC_USP7_UBL2_3	189	193	PF12436	0.402
DOC_WW_Pin1_4	212	217	PF00397	0.423
DOC_WW_Pin1_4	224	229	PF00397	0.356
DOC_WW_Pin1_4	269	274	PF00397	0.295
DOC_WW_Pin1_4	7	12	PF00397	0.385
LIG_14-3-3_CanoR_1	195	205	PF00244	0.537
LIG_Actin_WH2_2	77	95	PF00022	0.521
LIG_BIR_II_1	1	5	PF00653	0.377
LIG_BRCT_BRCA1_1	1	5	PF00533	0.359
LIG_FHA_1	127	133	PF00498	0.327
LIG_FHA_1	173	179	PF00498	0.515
LIG_FHA_1	213	219	PF00498	0.419
LIG_FHA_1	274	280	PF00498	0.305
LIG_FHA_1	38	44	PF00498	0.365
LIG_FHA_1	72	78	PF00498	0.271
LIG_FHA_2	270	276	PF00498	0.331
LIG_LIR_Apic_2	129	133	PF02991	0.331
LIG_LIR_Gen_1	121	132	PF02991	0.252
LIG_LIR_Gen_1	204	214	PF02991	0.416
LIG_LIR_Gen_1	249	258	PF02991	0.214
LIG_LIR_Gen_1	272	281	PF02991	0.252
LIG_LIR_Gen_1	72	81	PF02991	0.389
LIG_LIR_Nem_3	121	127	PF02991	0.261
LIG_LIR_Nem_3	204	209	PF02991	0.416
LIG_LIR_Nem_3	249	253	PF02991	0.225
LIG_LIR_Nem_3	272	277	PF02991	0.255
LIG_LIR_Nem_3	311	316	PF02991	0.671
LIG_LIR_Nem_3	63	69	PF02991	0.382
LIG_LIR_Nem_3	72	78	PF02991	0.380
LIG_NRBOX	64	70	PF00104	0.220
LIG_PCNA_PIPBox_1	161	170	PF02747	0.220
LIG_Pex14_1	114	118	PF04695	0.391
LIG_Pex14_2	62	66	PF04695	0.281
LIG_Rb_pABgroove_1	15	23	PF01858	0.300
LIG_SH2_STAT5	124	127	PF00017	0.252
LIG_SH2_STAT5	154	157	PF00017	0.271
LIG_SH2_STAT5	208	211	PF00017	0.440
LIG_SH2_STAT5	250	253	PF00017	0.214
LIG_SH2_STAT5	70	73	PF00017	0.290
LIG_SH3_1	213	219	PF00018	0.414
LIG_SH3_3	213	219	PF00018	0.438
LIG_SH3_3	320	326	PF00018	0.670
LIG_SH3_3	44	50	PF00018	0.357
LIG_SH3_3	54	60	PF00018	0.214
LIG_Sin3_3	31	38	PF02671	0.255
LIG_SUMO_SIM_anti_2	15	25	PF11976	0.465
LIG_SUMO_SIM_anti_2	282	288	PF11976	0.301
LIG_SUMO_SIM_par_1	275	282	PF11976	0.389
LIG_TYR_ITIM	122	127	PF00017	0.135
LIG_WRC_WIRS_1	127	132	PF05994	0.331
LIG_WRC_WIRS_1	234	239	PF05994	0.354
MOD_CK1_1	12	18	PF00069	0.430
MOD_CK1_1	196	202	PF00069	0.462
MOD_CK1_1	24	30	PF00069	0.359
MOD_CK1_1	314	320	PF00069	0.725
MOD_CK1_1	76	82	PF00069	0.425
MOD_CK1_1	91	97	PF00069	0.478
MOD_CK2_1	173	179	PF00069	0.508
MOD_GlcNHglycan	1	4	PF01048	0.659
MOD_GlcNHglycan	149	152	PF01048	0.212
MOD_GlcNHglycan	25	29	PF01048	0.645
MOD_GlcNHglycan	260	263	PF01048	0.580
MOD_GlcNHglycan	304	307	PF01048	0.455
MOD_GlcNHglycan	313	316	PF01048	0.449
MOD_GlcNHglycan	319	322	PF01048	0.500
MOD_GlcNHglycan	7	10	PF01048	0.553
MOD_GlcNHglycan	93	96	PF01048	0.332
MOD_GSK3_1	153	160	PF00069	0.270
MOD_GSK3_1	189	196	PF00069	0.514
MOD_GSK3_1	20	27	PF00069	0.345
MOD_GSK3_1	254	261	PF00069	0.246
MOD_GSK3_1	269	276	PF00069	0.271
MOD_GSK3_1	5	12	PF00069	0.427
MOD_GSK3_1	69	76	PF00069	0.360
MOD_GSK3_1	87	94	PF00069	0.481
MOD_NEK2_1	118	123	PF00069	0.280
MOD_NEK2_1	13	18	PF00069	0.421
MOD_NEK2_1	157	162	PF00069	0.242
MOD_NEK2_1	167	172	PF00069	0.315
MOD_NEK2_1	258	263	PF00069	0.392
MOD_NEK2_1	279	284	PF00069	0.338
MOD_NEK2_1	296	301	PF00069	0.455
MOD_NEK2_1	37	42	PF00069	0.345
MOD_NEK2_1	69	74	PF00069	0.249
MOD_NEK2_2	73	78	PF00069	0.364
MOD_PIKK_1	193	199	PF00454	0.495
MOD_PKA_2	311	317	PF00069	0.710
MOD_Plk_1	24	30	PF00069	0.290
MOD_Plk_1	87	93	PF00069	0.548
MOD_Plk_4	132	138	PF00069	0.254
MOD_Plk_4	153	159	PF00069	0.271
MOD_Plk_4	173	179	PF00069	0.457
MOD_Plk_4	238	244	PF00069	0.251
MOD_Plk_4	246	252	PF00069	0.254
MOD_Plk_4	273	279	PF00069	0.289
MOD_Plk_4	282	288	PF00069	0.326
MOD_ProDKin_1	212	218	PF00069	0.423
MOD_ProDKin_1	224	230	PF00069	0.356
MOD_ProDKin_1	269	275	PF00069	0.295
MOD_ProDKin_1	7	13	PF00069	0.386
MOD_SUMO_rev_2	261	270	PF00179	0.466
TRG_AP2beta_CARGO_1	204	213	PF09066	0.414
TRG_ENDOCYTIC_2	113	116	PF00928	0.507
TRG_ENDOCYTIC_2	124	127	PF00928	0.202
TRG_ENDOCYTIC_2	154	157	PF00928	0.271
TRG_ENDOCYTIC_2	208	211	PF00928	0.414
TRG_ENDOCYTIC_2	250	253	PF00928	0.214
TRG_NLS_MonoExtN_4	291	297	PF00514	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZM9	Leptomonas seymouri	73%	100%
A0A1X0NMH8	Trypanosomatidae	61%	100%
A0A422NV37	Trypanosoma rangeli	56%	100%
A4H703	Leishmania braziliensis	80%	100%
A4II98	Xenopus tropicalis	30%	100%
C9ZI22	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
E9AGI5	Leishmania infantum	100%	100%
E9AP23	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
O62126	Caenorhabditis elegans	30%	100%
Q08D99	Bos taurus	32%	100%
Q4QGG6	Leishmania major	85%	100%
Q5BJD5	Homo sapiens	29%	100%
Q5FVN2	Rattus norvegicus	30%	100%
Q5RBZ8	Pongo abelii	29%	100%
Q5U4K5	Xenopus laevis	30%	100%
Q5ZIL6	Gallus gallus	30%	100%
Q96HV5	Homo sapiens	31%	100%
Q9D8U2	Mus musculus	30%	100%
Q9VX39	Drosophila melanogaster	31%	100%
V5BJQ3	Trypanosoma cruzi	58%	100%