Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8I9D3_LEIDO

TriTrypDb:

LdBPK_160620.1 , LdCL_160011300 , LDHU3_16.0750

Length:

1135

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I9D3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I9D3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1050	1054	PF00656	0.558
CLV_C14_Caspase3-7	174	178	PF00656	0.659
CLV_C14_Caspase3-7	587	591	PF00656	0.538
CLV_C14_Caspase3-7	687	691	PF00656	0.550
CLV_C14_Caspase3-7	891	895	PF00656	0.640
CLV_C14_Caspase3-7	993	997	PF00656	0.577
CLV_MEL_PAP_1	47	53	PF00089	0.577
CLV_NRD_NRD_1	147	149	PF00675	0.677
CLV_NRD_NRD_1	237	239	PF00675	0.628
CLV_NRD_NRD_1	317	319	PF00675	0.546
CLV_NRD_NRD_1	4	6	PF00675	0.627
CLV_NRD_NRD_1	545	547	PF00675	0.582
CLV_NRD_NRD_1	767	769	PF00675	0.548
CLV_PCSK_FUR_1	765	769	PF00082	0.519
CLV_PCSK_KEX2_1	239	241	PF00082	0.685
CLV_PCSK_KEX2_1	317	319	PF00082	0.585
CLV_PCSK_KEX2_1	4	6	PF00082	0.627
CLV_PCSK_KEX2_1	545	547	PF00082	0.578
CLV_PCSK_KEX2_1	765	767	PF00082	0.576
CLV_PCSK_PC1ET2_1	239	241	PF00082	0.685
CLV_PCSK_SKI1_1	1088	1092	PF00082	0.641
CLV_PCSK_SKI1_1	188	192	PF00082	0.640
CLV_PCSK_SKI1_1	247	251	PF00082	0.611
CLV_PCSK_SKI1_1	269	273	PF00082	0.598
CLV_PCSK_SKI1_1	852	856	PF00082	0.535
CLV_PCSK_SKI1_1	91	95	PF00082	0.562
DEG_SCF_TRCP1_1	706	711	PF00400	0.536
DEG_SPOP_SBC_1	207	211	PF00917	0.635
DEG_SPOP_SBC_1	215	219	PF00917	0.611
DOC_CKS1_1	270	275	PF01111	0.567
DOC_CYCLIN_yCln2_LP_2	340	346	PF00134	0.574
DOC_CYCLIN_yCln2_LP_2	428	434	PF00134	0.529
DOC_MAPK_gen_1	1033	1041	PF00069	0.556
DOC_MAPK_gen_1	1107	1114	PF00069	0.531
DOC_MAPK_gen_1	330	340	PF00069	0.652
DOC_MAPK_MEF2A_6	1107	1114	PF00069	0.581
DOC_MAPK_MEF2A_6	848	857	PF00069	0.641
DOC_PP2B_LxvP_1	1049	1052	PF13499	0.558
DOC_PP2B_LxvP_1	338	341	PF13499	0.585
DOC_PP4_FxxP_1	354	357	PF00568	0.533
DOC_PP4_FxxP_1	469	472	PF00568	0.632
DOC_USP7_MATH_1	1042	1046	PF00917	0.478
DOC_USP7_MATH_1	1090	1094	PF00917	0.686
DOC_USP7_MATH_1	115	119	PF00917	0.692
DOC_USP7_MATH_1	205	209	PF00917	0.596
DOC_USP7_MATH_1	226	230	PF00917	0.624
DOC_USP7_MATH_1	370	374	PF00917	0.604
DOC_USP7_MATH_1	389	393	PF00917	0.535
DOC_USP7_MATH_1	437	441	PF00917	0.547
DOC_USP7_MATH_1	502	506	PF00917	0.526
DOC_USP7_MATH_1	559	563	PF00917	0.621
DOC_USP7_MATH_1	582	586	PF00917	0.611
DOC_USP7_MATH_1	674	678	PF00917	0.588
DOC_USP7_MATH_1	704	708	PF00917	0.617
DOC_USP7_MATH_1	883	887	PF00917	0.628
DOC_USP7_MATH_1	888	892	PF00917	0.662
DOC_USP7_MATH_1	898	902	PF00917	0.647
DOC_USP7_MATH_1	93	97	PF00917	0.621
DOC_USP7_MATH_1	950	954	PF00917	0.693
DOC_WW_Pin1_4	105	110	PF00397	0.646
DOC_WW_Pin1_4	1077	1082	PF00397	0.609
DOC_WW_Pin1_4	116	121	PF00397	0.580
DOC_WW_Pin1_4	216	221	PF00397	0.688
DOC_WW_Pin1_4	233	238	PF00397	0.590
DOC_WW_Pin1_4	259	264	PF00397	0.731
DOC_WW_Pin1_4	269	274	PF00397	0.590
DOC_WW_Pin1_4	339	344	PF00397	0.551
DOC_WW_Pin1_4	375	380	PF00397	0.825
DOC_WW_Pin1_4	40	45	PF00397	0.736
DOC_WW_Pin1_4	427	432	PF00397	0.596
DOC_WW_Pin1_4	433	438	PF00397	0.578
DOC_WW_Pin1_4	463	468	PF00397	0.674
DOC_WW_Pin1_4	486	491	PF00397	0.585
DOC_WW_Pin1_4	565	570	PF00397	0.577
DOC_WW_Pin1_4	614	619	PF00397	0.580
DOC_WW_Pin1_4	76	81	PF00397	0.768
DOC_WW_Pin1_4	839	844	PF00397	0.577
DOC_WW_Pin1_4	908	913	PF00397	0.613
DOC_WW_Pin1_4	928	933	PF00397	0.496
LIG_14-3-3_CanoR_1	330	340	PF00244	0.614
LIG_14-3-3_CanoR_1	356	366	PF00244	0.485
LIG_14-3-3_CanoR_1	545	549	PF00244	0.632
LIG_14-3-3_CanoR_1	567	573	PF00244	0.574
LIG_14-3-3_CanoR_1	662	670	PF00244	0.571
LIG_14-3-3_CanoR_1	766	774	PF00244	0.575
LIG_14-3-3_CanoR_1	848	852	PF00244	0.643
LIG_14-3-3_CanoR_1	91	99	PF00244	0.555
LIG_14-3-3_CanoR_1	942	950	PF00244	0.632
LIG_14-3-3_CanoR_1	976	982	PF00244	0.542
LIG_14-3-3_CanoR_1	998	1006	PF00244	0.570
LIG_BIR_II_1	1	5	PF00653	0.643
LIG_BIR_III_2	894	898	PF00653	0.629
LIG_BIR_III_4	84	88	PF00653	0.599
LIG_BRCT_BRCA1_1	394	398	PF00533	0.563
LIG_BRCT_BRCA1_1	465	469	PF00533	0.668
LIG_FHA_1	1098	1104	PF00498	0.645
LIG_FHA_1	1127	1133	PF00498	0.595
LIG_FHA_1	123	129	PF00498	0.633
LIG_FHA_1	155	161	PF00498	0.650
LIG_FHA_1	189	195	PF00498	0.642
LIG_FHA_1	209	215	PF00498	0.516
LIG_FHA_1	248	254	PF00498	0.607
LIG_FHA_1	423	429	PF00498	0.516
LIG_FHA_1	665	671	PF00498	0.548
LIG_FHA_1	695	701	PF00498	0.627
LIG_FHA_1	752	758	PF00498	0.482
LIG_FHA_1	968	974	PF00498	0.631
LIG_FHA_1	976	982	PF00498	0.487
LIG_FHA_2	1023	1029	PF00498	0.561
LIG_FHA_2	1048	1054	PF00498	0.547
LIG_FHA_2	260	266	PF00498	0.615
LIG_FHA_2	434	440	PF00498	0.594
LIG_FHA_2	585	591	PF00498	0.551
LIG_FHA_2	645	651	PF00498	0.683
LIG_FHA_2	685	691	PF00498	0.614
LIG_Integrin_RGD_1	588	590	PF01839	0.650
LIG_LIR_Apic_2	466	472	PF02991	0.635
LIG_LIR_Gen_1	395	405	PF02991	0.566
LIG_LIR_Gen_1	407	418	PF02991	0.497
LIG_LIR_Gen_1	632	642	PF02991	0.595
LIG_LIR_Nem_3	395	401	PF02991	0.628
LIG_LIR_Nem_3	407	413	PF02991	0.465
LIG_LIR_Nem_3	532	536	PF02991	0.555
LIG_LIR_Nem_3	632	638	PF02991	0.595
LIG_RPA_C_Fungi	762	774	PF08784	0.510
LIG_SH2_PTP2	635	638	PF00017	0.653
LIG_SH2_SRC	224	227	PF00017	0.547
LIG_SH2_STAP1	1130	1134	PF00017	0.605
LIG_SH2_STAT5	224	227	PF00017	0.566
LIG_SH2_STAT5	635	638	PF00017	0.653
LIG_SH2_STAT5	782	785	PF00017	0.576
LIG_SH3_3	1000	1006	PF00018	0.474
LIG_SH3_3	106	112	PF00018	0.650
LIG_SH3_3	1078	1084	PF00018	0.616
LIG_SH3_3	201	207	PF00018	0.603
LIG_SH3_3	21	27	PF00018	0.489
LIG_SH3_3	260	266	PF00018	0.775
LIG_SH3_3	267	273	PF00018	0.635
LIG_SH3_3	39	45	PF00018	0.574
LIG_SH3_3	453	459	PF00018	0.666
LIG_SH3_3	498	504	PF00018	0.560
LIG_SH3_3	785	791	PF00018	0.675
LIG_SH3_3	807	813	PF00018	0.614
LIG_SH3_3	929	935	PF00018	0.632
LIG_SH3_3	982	988	PF00018	0.607
LIG_SUMO_SIM_anti_2	616	623	PF11976	0.597
LIG_TRAF2_1	1006	1009	PF00917	0.573
LIG_TRAF2_1	1093	1096	PF00917	0.625
LIG_TRAF2_1	131	134	PF00917	0.605
LIG_TRAF2_1	262	265	PF00917	0.595
LIG_WW_3	471	475	PF00397	0.624
LIG_WW_3	808	812	PF00397	0.608
MOD_CDC14_SPxK_1	342	345	PF00782	0.532
MOD_CDK_SPK_2	1077	1082	PF00069	0.587
MOD_CDK_SPK_2	233	238	PF00069	0.593
MOD_CDK_SPK_2	928	933	PF00069	0.622
MOD_CDK_SPxK_1	233	239	PF00069	0.593
MOD_CDK_SPxK_1	339	345	PF00069	0.551
MOD_CDK_SPxxK_3	233	240	PF00069	0.594
MOD_CK1_1	1073	1079	PF00069	0.661
MOD_CK1_1	118	124	PF00069	0.598
MOD_CK1_1	208	214	PF00069	0.627
MOD_CK1_1	219	225	PF00069	0.687
MOD_CK1_1	233	239	PF00069	0.569
MOD_CK1_1	336	342	PF00069	0.518
MOD_CK1_1	392	398	PF00069	0.527
MOD_CK1_1	440	446	PF00069	0.570
MOD_CK1_1	486	492	PF00069	0.650
MOD_CK1_1	568	574	PF00069	0.632
MOD_CK1_1	584	590	PF00069	0.558
MOD_CK1_1	617	623	PF00069	0.580
MOD_CK1_1	664	670	PF00069	0.570
MOD_CK1_1	677	683	PF00069	0.663
MOD_CK1_1	691	697	PF00069	0.502
MOD_CK1_1	756	762	PF00069	0.643
MOD_CK1_1	842	848	PF00069	0.710
MOD_CK1_1	886	892	PF00069	0.626
MOD_CK1_1	901	907	PF00069	0.590
MOD_CK1_1	97	103	PF00069	0.596
MOD_CK2_1	1090	1096	PF00069	0.623
MOD_CK2_1	168	174	PF00069	0.652
MOD_CK2_1	251	257	PF00069	0.607
MOD_CK2_1	259	265	PF00069	0.587
MOD_CK2_1	644	650	PF00069	0.679
MOD_CMANNOS	508	511	PF00535	0.612
MOD_Cter_Amidation	2	5	PF01082	0.584
MOD_DYRK1A_RPxSP_1	269	273	PF00069	0.598
MOD_GlcNHglycan	1	4	PF01048	0.658
MOD_GlcNHglycan	1058	1061	PF01048	0.669
MOD_GlcNHglycan	1084	1087	PF01048	0.650
MOD_GlcNHglycan	1103	1106	PF01048	0.645
MOD_GlcNHglycan	13	16	PF01048	0.487
MOD_GlcNHglycan	162	167	PF01048	0.634
MOD_GlcNHglycan	230	235	PF01048	0.638
MOD_GlcNHglycan	386	390	PF01048	0.640
MOD_GlcNHglycan	391	394	PF01048	0.586
MOD_GlcNHglycan	413	416	PF01048	0.502
MOD_GlcNHglycan	485	488	PF01048	0.644
MOD_GlcNHglycan	561	564	PF01048	0.669
MOD_GlcNHglycan	575	578	PF01048	0.539
MOD_GlcNHglycan	584	587	PF01048	0.512
MOD_GlcNHglycan	601	604	PF01048	0.534
MOD_GlcNHglycan	672	675	PF01048	0.554
MOD_GlcNHglycan	676	679	PF01048	0.578
MOD_GlcNHglycan	690	693	PF01048	0.730
MOD_GlcNHglycan	706	709	PF01048	0.508
MOD_GlcNHglycan	761	764	PF01048	0.677
MOD_GlcNHglycan	774	777	PF01048	0.472
MOD_GlcNHglycan	806	809	PF01048	0.778
MOD_GlcNHglycan	869	872	PF01048	0.672
MOD_GlcNHglycan	890	893	PF01048	0.719
MOD_GlcNHglycan	900	903	PF01048	0.570
MOD_GlcNHglycan	928	931	PF01048	0.632
MOD_GlcNHglycan	960	963	PF01048	0.764
MOD_GlcNHglycan	999	1002	PF01048	0.634
MOD_GSK3_1	1009	1016	PF00069	0.554
MOD_GSK3_1	1022	1029	PF00069	0.503
MOD_GSK3_1	1070	1077	PF00069	0.688
MOD_GSK3_1	1097	1104	PF00069	0.609
MOD_GSK3_1	118	125	PF00069	0.608
MOD_GSK3_1	164	171	PF00069	0.614
MOD_GSK3_1	205	212	PF00069	0.629
MOD_GSK3_1	215	222	PF00069	0.679
MOD_GSK3_1	226	233	PF00069	0.687
MOD_GSK3_1	243	250	PF00069	0.517
MOD_GSK3_1	329	336	PF00069	0.596
MOD_GSK3_1	377	384	PF00069	0.741
MOD_GSK3_1	385	392	PF00069	0.620
MOD_GSK3_1	433	440	PF00069	0.556
MOD_GSK3_1	482	489	PF00069	0.611
MOD_GSK3_1	559	566	PF00069	0.617
MOD_GSK3_1	595	602	PF00069	0.597
MOD_GSK3_1	649	656	PF00069	0.587
MOD_GSK3_1	67	74	PF00069	0.661
MOD_GSK3_1	670	677	PF00069	0.537
MOD_GSK3_1	684	691	PF00069	0.612
MOD_GSK3_1	704	711	PF00069	0.585
MOD_GSK3_1	752	759	PF00069	0.740
MOD_GSK3_1	768	775	PF00069	0.479
MOD_GSK3_1	79	86	PF00069	0.571
MOD_GSK3_1	799	806	PF00069	0.624
MOD_GSK3_1	839	846	PF00069	0.642
MOD_GSK3_1	879	886	PF00069	0.664
MOD_GSK3_1	89	96	PF00069	0.663
MOD_GSK3_1	958	965	PF00069	0.747
MOD_N-GLC_1	37	42	PF02516	0.555
MOD_N-GLC_1	381	386	PF02516	0.602
MOD_N-GLC_1	898	903	PF02516	0.606
MOD_NEK2_1	1026	1031	PF00069	0.536
MOD_NEK2_1	1074	1079	PF00069	0.552
MOD_NEK2_1	164	169	PF00069	0.574
MOD_NEK2_1	17	22	PF00069	0.451
MOD_NEK2_1	245	250	PF00069	0.653
MOD_NEK2_1	281	286	PF00069	0.608
MOD_NEK2_1	561	566	PF00069	0.658
MOD_NEK2_1	592	597	PF00069	0.620
MOD_NEK2_1	688	693	PF00069	0.615
MOD_NEK2_1	783	788	PF00069	0.625
MOD_NEK2_1	966	971	PF00069	0.606
MOD_NEK2_2	847	852	PF00069	0.586
MOD_PIKK_1	164	170	PF00454	0.576
MOD_PIKK_1	440	446	PF00454	0.660
MOD_PIKK_1	79	85	PF00454	0.627
MOD_PIKK_1	948	954	PF00454	0.640
MOD_PK_1	784	790	PF00069	0.697
MOD_PKA_1	767	773	PF00069	0.504
MOD_PKA_2	115	121	PF00069	0.596
MOD_PKA_2	251	257	PF00069	0.562
MOD_PKA_2	329	335	PF00069	0.559
MOD_PKA_2	355	361	PF00069	0.476
MOD_PKA_2	440	446	PF00069	0.636
MOD_PKA_2	544	550	PF00069	0.628
MOD_PKA_2	661	667	PF00069	0.580
MOD_PKA_2	767	773	PF00069	0.580
MOD_PKA_2	783	789	PF00069	0.516
MOD_PKA_2	847	853	PF00069	0.592
MOD_PKA_2	941	947	PF00069	0.615
MOD_PKA_2	975	981	PF00069	0.549
MOD_PKA_2	997	1003	PF00069	0.578
MOD_PKB_1	765	773	PF00069	0.555
MOD_Plk_1	1027	1033	PF00069	0.570
MOD_Plk_1	123	129	PF00069	0.599
MOD_Plk_1	37	43	PF00069	0.560
MOD_Plk_1	629	635	PF00069	0.573
MOD_Plk_1	664	670	PF00069	0.512
MOD_Plk_1	694	700	PF00069	0.612
MOD_Plk_1	708	714	PF00069	0.498
MOD_Plk_1	784	790	PF00069	0.518
MOD_Plk_2-3	1070	1076	PF00069	0.619
MOD_Plk_4	1009	1015	PF00069	0.514
MOD_Plk_4	1042	1048	PF00069	0.478
MOD_Plk_4	17	23	PF00069	0.452
MOD_Plk_4	199	205	PF00069	0.605
MOD_Plk_4	220	226	PF00069	0.567
MOD_Plk_4	568	574	PF00069	0.567
MOD_Plk_4	617	623	PF00069	0.576
MOD_Plk_4	94	100	PF00069	0.592
MOD_ProDKin_1	105	111	PF00069	0.646
MOD_ProDKin_1	1077	1083	PF00069	0.609
MOD_ProDKin_1	116	122	PF00069	0.576
MOD_ProDKin_1	216	222	PF00069	0.688
MOD_ProDKin_1	233	239	PF00069	0.590
MOD_ProDKin_1	259	265	PF00069	0.734
MOD_ProDKin_1	269	275	PF00069	0.586
MOD_ProDKin_1	339	345	PF00069	0.551
MOD_ProDKin_1	375	381	PF00069	0.826
MOD_ProDKin_1	40	46	PF00069	0.739
MOD_ProDKin_1	427	433	PF00069	0.594
MOD_ProDKin_1	463	469	PF00069	0.675
MOD_ProDKin_1	486	492	PF00069	0.584
MOD_ProDKin_1	565	571	PF00069	0.576
MOD_ProDKin_1	614	620	PF00069	0.575
MOD_ProDKin_1	76	82	PF00069	0.766
MOD_ProDKin_1	839	845	PF00069	0.575
MOD_ProDKin_1	908	914	PF00069	0.613
MOD_ProDKin_1	928	934	PF00069	0.494
MOD_SUMO_rev_2	67	75	PF00179	0.598
TRG_DiLeu_BaEn_2	694	700	PF01217	0.543
TRG_DiLeu_BaLyEn_6	24	29	PF01217	0.475
TRG_ENDOCYTIC_2	635	638	PF00928	0.653
TRG_ER_diArg_1	1036	1039	PF00400	0.555
TRG_ER_diArg_1	1107	1110	PF00400	0.562
TRG_ER_diArg_1	237	240	PF00400	0.640
TRG_ER_diArg_1	4	6	PF00400	0.627
TRG_ER_diArg_1	765	768	PF00400	0.569
TRG_NLS_MonoExtC_3	237	242	PF00514	0.683
TRG_NLS_MonoExtN_4	237	243	PF00514	0.638
TRG_Pf-PMV_PEXEL_1	1024	1028	PF00026	0.558
TRG_Pf-PMV_PEXEL_1	345	349	PF00026	0.506
TRG_Pf-PMV_PEXEL_1	514	519	PF00026	0.592
TRG_Pf-PMV_PEXEL_1	546	551	PF00026	0.631

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWB0	Leptomonas seymouri	27%	100%
A4H8I4	Leishmania braziliensis	61%	99%
A4HWW1	Leishmania infantum	99%	100%
E9AQM1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	99%
Q4QEV7	Leishmania major	84%	100%