Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3Q8I979_LEIDO

TriTrypDb:

LdBPK_120450.1 , LdCL_120010100 , LDHU3_12.0650

Length:

317

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I979

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I979

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	39	41	PF00675	0.666
CLV_PCSK_KEX2_1	39	41	PF00082	0.666
DOC_MAPK_gen_1	39	47	PF00069	0.654
DOC_PP2B_LxvP_1	29	32	PF13499	0.775
DOC_PP4_FxxP_1	74	77	PF00568	0.823
DOC_USP7_MATH_1	129	133	PF00917	0.813
DOC_USP7_MATH_1	13	17	PF00917	0.611
DOC_USP7_MATH_1	155	159	PF00917	0.804
DOC_USP7_MATH_1	171	175	PF00917	0.647
DOC_USP7_MATH_1	198	202	PF00917	0.776
DOC_USP7_MATH_1	22	26	PF00917	0.646
DOC_USP7_MATH_1	32	36	PF00917	0.675
DOC_USP7_MATH_1	51	55	PF00917	0.491
DOC_USP7_MATH_2	165	171	PF00917	0.834
DOC_WW_Pin1_4	151	156	PF00397	0.817
DOC_WW_Pin1_4	226	231	PF00397	0.818
LIG_14-3-3_CanoR_1	11	19	PF00244	0.683
LIG_BIR_II_1	1	5	PF00653	0.663
LIG_deltaCOP1_diTrp_1	214	223	PF00928	0.783
LIG_FHA_1	136	142	PF00498	0.803
LIG_FHA_1	36	42	PF00498	0.663
LIG_FHA_2	265	271	PF00498	0.718
LIG_LIR_Apic_2	60	65	PF02991	0.768
LIG_LIR_LC3C_4	42	46	PF02991	0.712
LIG_LIR_Nem_3	237	241	PF02991	0.819
LIG_Pex14_1	182	186	PF04695	0.790
LIG_SH2_CRK	62	66	PF00017	0.727
LIG_SH2_STAT5	3	6	PF00017	0.625
LIG_SH2_STAT5	62	65	PF00017	0.729
LIG_SH3_3	42	48	PF00018	0.751
LIG_SH3_3	74	80	PF00018	0.674
LIG_SH3_3	92	98	PF00018	0.848
LIG_SUMO_SIM_anti_2	42	48	PF11976	0.710
LIG_TRAF2_1	230	233	PF00917	0.832
LIG_TRAF2_1	296	299	PF00917	0.783
MOD_CDK_SPK_2	226	231	PF00069	0.818
MOD_CK1_1	127	133	PF00069	0.832
MOD_CK1_1	15	21	PF00069	0.725
MOD_CK1_1	226	232	PF00069	0.820
MOD_CK1_1	35	41	PF00069	0.543
MOD_CK1_1	60	66	PF00069	0.766
MOD_CK1_1	85	91	PF00069	0.797
MOD_CK2_1	15	21	PF00069	0.720
MOD_CK2_1	226	232	PF00069	0.685
MOD_CK2_1	264	270	PF00069	0.696
MOD_CK2_1	292	298	PF00069	0.673
MOD_CK2_1	72	78	PF00069	0.791
MOD_GlcNHglycan	113	116	PF01048	0.762
MOD_GlcNHglycan	131	134	PF01048	0.780
MOD_GlcNHglycan	169	172	PF01048	0.797
MOD_GlcNHglycan	187	190	PF01048	0.517
MOD_GlcNHglycan	204	207	PF01048	0.492
MOD_GlcNHglycan	224	228	PF01048	0.490
MOD_GlcNHglycan	250	253	PF01048	0.771
MOD_GlcNHglycan	294	297	PF01048	0.693
MOD_GlcNHglycan	34	37	PF01048	0.773
MOD_GlcNHglycan	53	56	PF01048	0.497
MOD_GlcNHglycan	85	88	PF01048	0.687
MOD_GSK3_1	107	114	PF00069	0.771
MOD_GSK3_1	11	18	PF00069	0.713
MOD_GSK3_1	124	131	PF00069	0.594
MOD_GSK3_1	145	152	PF00069	0.686
MOD_GSK3_1	163	170	PF00069	0.787
MOD_GSK3_1	187	194	PF00069	0.647
MOD_GSK3_1	198	205	PF00069	0.580
MOD_GSK3_1	20	27	PF00069	0.644
MOD_GSK3_1	219	226	PF00069	0.799
MOD_GSK3_1	244	251	PF00069	0.660
MOD_GSK3_1	31	38	PF00069	0.558
MOD_GSK3_1	53	60	PF00069	0.748
MOD_N-GLC_1	202	207	PF02516	0.719
MOD_N-GLC_1	83	88	PF02516	0.709
MOD_NEK2_1	107	112	PF00069	0.811
MOD_NEK2_1	149	154	PF00069	0.806
MOD_NEK2_1	223	228	PF00069	0.814
MOD_PIKK_1	187	193	PF00454	0.630
MOD_PIKK_1	57	63	PF00454	0.727
MOD_Plk_4	107	113	PF00069	0.750
MOD_Plk_4	157	163	PF00069	0.760
MOD_Plk_4	24	30	PF00069	0.733
MOD_ProDKin_1	151	157	PF00069	0.817
MOD_ProDKin_1	226	232	PF00069	0.820
MOD_SUMO_rev_2	88	98	PF00179	0.791
TRG_DiLeu_BaLyEn_6	68	73	PF01217	0.797
TRG_ER_diArg_1	39	41	PF00400	0.666
TRG_Pf-PMV_PEXEL_1	175	179	PF00026	0.772

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H6W8	Leishmania braziliensis	70%	100%
E9AGD7	Leishmania infantum	99%	100%
E9ANX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4QGP3	Leishmania major	91%	100%