LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8I949_LEIDO
TriTrypDb:
LdBPK_120075.1 , LdCL_120005800 , LDHU3_12.0110
Length:
90

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4
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Expansion

Sequence features

A0A3Q8I949
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I949

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 54 58 PF00656 0.694
CLV_PCSK_SKI1_1 31 35 PF00082 0.537
CLV_PCSK_SKI1_1 73 77 PF00082 0.376
DEG_APCC_DBOX_1 72 80 PF00400 0.327
DEG_Nend_UBRbox_2 1 3 PF02207 0.792
DOC_CYCLIN_RxL_1 28 37 PF00134 0.735
DOC_MAPK_MEF2A_6 73 82 PF00069 0.520
DOC_MAPK_NFAT4_5 73 81 PF00069 0.426
DOC_PP4_FxxP_1 47 50 PF00568 0.723
DOC_WW_Pin1_4 16 21 PF00397 0.658
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Homologs

ProteinTaxonomySequence identityCoverage
A4H6S3 Leishmania braziliensis 72% 100%
E9ACR2 Leishmania major 88% 100%
E9AGA4 Leishmania infantum 100% 100%
E9ANT4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS