Cell_cycle_sequence_binding_phosphoprotein_(RBP45 )_putative/GeneDB:LmjF.11.0140

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3Q8I8Y8_LEIDO

TriTrypDb:

LdBPK_110140.1 , LdCL_110006300 , LDHU3_11.0160

Length:

292

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3Q8I8Y8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I8Y8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	185	189	PF00656	0.442
CLV_NRD_NRD_1	122	124	PF00675	0.646
CLV_NRD_NRD_1	150	152	PF00675	0.425
CLV_NRD_NRD_1	254	256	PF00675	0.301
CLV_PCSK_FUR_1	120	124	PF00082	0.710
CLV_PCSK_KEX2_1	120	122	PF00082	0.609
CLV_PCSK_KEX2_1	150	152	PF00082	0.425
CLV_PCSK_KEX2_1	254	256	PF00082	0.432
CLV_PCSK_PC1ET2_1	150	152	PF00082	0.386
CLV_PCSK_SKI1_1	152	156	PF00082	0.393
CLV_PCSK_SKI1_1	255	259	PF00082	0.320
DEG_SPOP_SBC_1	288	292	PF00917	0.443
DOC_CKS1_1	132	137	PF01111	0.577
DOC_CKS1_1	63	68	PF01111	0.547
DOC_MAPK_gen_1	204	214	PF00069	0.313
DOC_PP1_RVXF_1	253	260	PF00149	0.273
DOC_PP1_RVXF_1	264	270	PF00149	0.294
DOC_USP7_MATH_1	288	292	PF00917	0.623
DOC_USP7_UBL2_3	200	204	PF12436	0.649
DOC_WW_Pin1_4	131	136	PF00397	0.623
DOC_WW_Pin1_4	156	161	PF00397	0.422
DOC_WW_Pin1_4	62	67	PF00397	0.546
DOC_WW_Pin1_4	77	82	PF00397	0.596
LIG_14-3-3_CanoR_1	207	212	PF00244	0.317
LIG_14-3-3_CanoR_1	23	29	PF00244	0.468
LIG_14-3-3_CanoR_1	254	260	PF00244	0.324
LIG_FHA_1	2	8	PF00498	0.625
LIG_FHA_1	224	230	PF00498	0.432
LIG_FHA_1	35	41	PF00498	0.534
LIG_FHA_2	132	138	PF00498	0.710
LIG_FHA_2	183	189	PF00498	0.409
LIG_FHA_2	220	226	PF00498	0.324
LIG_LIR_Apic_2	159	165	PF02991	0.382
LIG_LIR_Gen_1	258	269	PF02991	0.328
LIG_LIR_Nem_3	268	272	PF02991	0.310
LIG_LIR_Nem_3	275	280	PF02991	0.297
LIG_PCNA_yPIPBox_3	15	23	PF02747	0.394
LIG_SH2_NCK_1	157	161	PF00017	0.420
LIG_SH2_PTP2	162	165	PF00017	0.377
LIG_SH2_STAP1	95	99	PF00017	0.537
LIG_SH2_STAT5	162	165	PF00017	0.377
LIG_SH2_STAT5	71	74	PF00017	0.736
LIG_SH3_3	108	114	PF00018	0.690
LIG_SH3_3	126	132	PF00018	0.714
LIG_SH3_3	48	54	PF00018	0.522
LIG_SUMO_SIM_par_1	210	215	PF11976	0.389
LIG_TRAF2_1	114	117	PF00917	0.628
LIG_TYR_ITIM	93	98	PF00017	0.557
LIG_WRC_WIRS_1	277	282	PF05994	0.284
LIG_WW_3	65	69	PF00397	0.708
MOD_CDK_SPxK_1	62	68	PF00069	0.560
MOD_CK2_1	131	137	PF00069	0.745
MOD_CK2_1	207	213	PF00069	0.310
MOD_CK2_1	219	225	PF00069	0.338
MOD_GlcNHglycan	238	241	PF01048	0.388
MOD_GlcNHglycan	56	59	PF01048	0.699
MOD_GlcNHglycan	77	80	PF01048	0.734
MOD_GSK3_1	101	108	PF00069	0.529
MOD_GSK3_1	219	226	PF00069	0.473
MOD_GSK3_1	82	89	PF00069	0.669
MOD_N-GLC_1	2	7	PF02516	0.652
MOD_N-GLC_1	75	80	PF02516	0.740
MOD_NEK2_1	1	6	PF00069	0.595
MOD_NEK2_1	212	217	PF00069	0.297
MOD_NEK2_1	276	281	PF00069	0.312
MOD_NEK2_1	29	34	PF00069	0.532
MOD_NEK2_2	260	265	PF00069	0.328
MOD_PIKK_1	212	218	PF00454	0.324
MOD_PK_1	207	213	PF00069	0.432
MOD_PKA_1	255	261	PF00069	0.322
MOD_PKA_2	22	28	PF00069	0.582
MOD_Plk_1	2	8	PF00069	0.648
MOD_Plk_1	212	218	PF00069	0.297
MOD_Plk_4	2	8	PF00069	0.607
MOD_Plk_4	207	213	PF00069	0.354
MOD_Plk_4	255	261	PF00069	0.280
MOD_ProDKin_1	131	137	PF00069	0.620
MOD_ProDKin_1	156	162	PF00069	0.425
MOD_ProDKin_1	62	68	PF00069	0.550
MOD_ProDKin_1	77	83	PF00069	0.599
TRG_DiLeu_BaEn_1	177	182	PF01217	0.367
TRG_ENDOCYTIC_2	261	264	PF00928	0.328
TRG_ENDOCYTIC_2	277	280	PF00928	0.284
TRG_ENDOCYTIC_2	95	98	PF00928	0.538
TRG_ER_diArg_1	120	123	PF00400	0.612
TRG_ER_diArg_1	151	154	PF00400	0.392
TRG_ER_diArg_1	280	283	PF00400	0.307
TRG_NES_CRM1_1	39	50	PF08389	0.522
TRG_NLS_MonoCore_2	149	154	PF00514	0.395
TRG_NLS_MonoExtN_4	150	155	PF00514	0.399
TRG_Pf-PMV_PEXEL_1	153	158	PF00026	0.387
TRG_Pf-PMV_PEXEL_1	270	275	PF00026	0.326
TRG_Pf-PMV_PEXEL_1	41	45	PF00026	0.595

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8D9	Leptomonas seymouri	35%	100%
A0A0N1PAZ1	Leptomonas seymouri	84%	100%
A0A0S4JV55	Bodo saltans	50%	87%
A0A1X0NWX9	Trypanosomatidae	56%	97%
A0A3S5ISC8	Trypanosoma rangeli	52%	97%
A4H9U4	Leishmania braziliensis	92%	100%
A4HNG2	Leishmania braziliensis	27%	100%
A4HUS6	Leishmania infantum	100%	100%
D0A7N8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	93%
E9ANG0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
Q4QH66	Leishmania major	97%	100%
V5BB20	Trypanosoma cruzi	57%	97%
V5DLK4	Trypanosoma cruzi	51%	66%