LeishMANIAdb
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Hypothetical_protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3Q8I8U8_LEIDO
TriTrypDb:
LdCL_140015300 , LDHU3_14.1220
Length:
74

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I8U8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I8U8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 44 46 PF00675 0.510
CLV_PCSK_KEX2_1 22 24 PF00082 0.320
CLV_PCSK_PC1ET2_1 22 24 PF00082 0.320
CLV_PCSK_SKI1_1 23 27 PF00082 0.225
CLV_PCSK_SKI1_1 46 50 PF00082 0.548
CLV_Separin_Metazoa 42 46 PF03568 0.365
DOC_PP1_RVXF_1 21 28 PF00149 0.425
DOC_USP7_MATH_1 59 63 PF00917 0.516
DOC_USP7_UBL2_3 67 71 PF12436 0.462
LIG_BRCT_BRCA1_1 61 65 PF00533 0.452
LIG_BRCT_BRCA1_2 61 67 PF00533 0.452
LIG_LIR_Nem_3 24 30 PF02991 0.262
LIG_Pex14_2 29 33 PF04695 0.249
LIG_SH3_3 1 7 PF00018 0.599
LIG_TRAF2_1 53 56 PF00917 0.439
MOD_GlcNHglycan 71 74 PF01048 0.677
MOD_GSK3_1 65 72 PF00069 0.447
MOD_NEK2_1 17 22 PF00069 0.547
MOD_NEK2_1 65 70 PF00069 0.411
TRG_ER_diLys_1 69 74 PF00400 0.472

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCC8 Leptomonas seymouri 67% 76%
C9ZSZ2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 95%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS