LeishMANIAdb
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ULP_PROTEASE domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ULP_PROTEASE domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8I8U5_LEIDO
TriTrypDb:
LdBPK_100850.1 * , LdCL_100015300 , LDHU3_10.1210
Length:
1080

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I8U5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I8U5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 28 32 PF00656 0.543
CLV_C14_Caspase3-7 419 423 PF00656 0.532
CLV_NRD_NRD_1 1006 1008 PF00675 0.724
CLV_NRD_NRD_1 1024 1026 PF00675 0.558
CLV_NRD_NRD_1 1028 1030 PF00675 0.782
CLV_NRD_NRD_1 1076 1078 PF00675 0.658
CLV_NRD_NRD_1 172 174 PF00675 0.715
CLV_NRD_NRD_1 2 4 PF00675 0.559
CLV_NRD_NRD_1 234 236 PF00675 0.669
CLV_NRD_NRD_1 357 359 PF00675 0.571
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Homologs

ProteinTaxonomySequence identityCoverage
A4H668 Leishmania braziliensis 68% 86%
A4HUJ2 Leishmania infantum 100% 100%
C9ZVL7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 37% 100%
E9AN90 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4QHD4 Leishmania major 89% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS