LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3Q8I8I3_LEIDO
TriTrypDb:
LdBPK_130750.1 , LdCL_130012900 , LDHU3_13.0950
Length:
392

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I8I3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I8I3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 326 330 PF00656 0.647
CLV_NRD_NRD_1 101 103 PF00675 0.646
CLV_NRD_NRD_1 105 107 PF00675 0.622
CLV_NRD_NRD_1 188 190 PF00675 0.582
CLV_NRD_NRD_1 205 207 PF00675 0.601
CLV_NRD_NRD_1 228 230 PF00675 0.564
CLV_NRD_NRD_1 293 295 PF00675 0.592
CLV_PCSK_FUR_1 358 362 PF00082 0.516
CLV_PCSK_FUR_1 99 103 PF00082 0.614
CLV_PCSK_KEX2_1 101 103 PF00082 0.646
CLV_PCSK_KEX2_1 105 107 PF00082 0.622
CLV_PCSK_KEX2_1 169 171 PF00082 0.578
CLV_PCSK_KEX2_1 188 190 PF00082 0.582
CLV_PCSK_KEX2_1 205 207 PF00082 0.601
CLV_PCSK_KEX2_1 228 230 PF00082 0.547
CLV_PCSK_KEX2_1 295 297 PF00082 0.698
CLV_PCSK_KEX2_1 360 362 PF00082 0.529
CLV_PCSK_PC1ET2_1 169 171 PF00082 0.578
CLV_PCSK_PC1ET2_1 295 297 PF00082 0.698
CLV_PCSK_PC1ET2_1 360 362 PF00082 0.534
CLV_PCSK_PC7_1 101 107 PF00082 0.627
CLV_PCSK_PC7_1 356 362 PF00082 0.498
CLV_PCSK_SKI1_1 189 193 PF00082 0.728
CLV_PCSK_SKI1_1 296 300 PF00082 0.698
CLV_PCSK_SKI1_1 65 69 PF00082 0.584
DEG_Nend_UBRbox_3 1 3 PF02207 0.539
DOC_CKS1_1 82 87 PF01111 0.567
DOC_MAPK_MEF2A_6 4 13 PF00069 0.557
DOC_PP2B_LxvP_1 33 36 PF13499 0.540
DOC_PP4_FxxP_1 172 175 PF00568 0.635
DOC_PP4_FxxP_1 179 182 PF00568 0.564
DOC_USP7_MATH_1 271 275 PF00917 0.611
DOC_USP7_MATH_1 373 377 PF00917 0.500
DOC_USP7_MATH_1 47 51 PF00917 0.607
DOC_USP7_MATH_1 54 58 PF00917 0.576
DOC_USP7_MATH_2 69 75 PF00917 0.579
DOC_USP7_UBL2_3 165 169 PF12436 0.583
DOC_WW_Pin1_4 65 70 PF00397 0.714
DOC_WW_Pin1_4 81 86 PF00397 0.570
DOC_WW_Pin1_4 92 97 PF00397 0.592
LIG_Actin_WH2_2 6 21 PF00022 0.565
LIG_AP2alpha_2 144 146 PF02296 0.565
LIG_BRCT_BRCA1_1 56 60 PF00533 0.753
LIG_BRCT_BRCA1_1 73 77 PF00533 0.476
LIG_CSL_BTD_1 183 186 PF09270 0.580
LIG_FHA_1 304 310 PF00498 0.655
LIG_FHA_1 70 76 PF00498 0.639
LIG_FHA_2 250 256 PF00498 0.537
LIG_FHA_2 344 350 PF00498 0.507
LIG_FHA_2 66 72 PF00498 0.605
LIG_Integrin_isoDGR_2 290 292 PF01839 0.653
LIG_LIR_Apic_2 176 182 PF02991 0.515
LIG_LIR_Apic_2 214 220 PF02991 0.620
LIG_LIR_Apic_2 80 85 PF02991 0.562
LIG_SH2_CRK 82 86 PF00017 0.616
LIG_SH3_3 150 156 PF00018 0.549
LIG_SH3_3 180 186 PF00018 0.555
LIG_SH3_3 187 193 PF00018 0.584
LIG_SH3_3 242 248 PF00018 0.592
LIG_SH3_3 315 321 PF00018 0.686
LIG_TRAF2_1 252 255 PF00917 0.593
LIG_TRAF2_1 50 53 PF00917 0.548
MOD_CDK_SPxxK_3 92 99 PF00069 0.620
MOD_CK1_1 307 313 PF00069 0.571
MOD_CK2_1 249 255 PF00069 0.539
MOD_CK2_1 343 349 PF00069 0.514
MOD_CK2_1 47 53 PF00069 0.617
MOD_CK2_1 65 71 PF00069 0.484
MOD_Cter_Amidation 103 106 PF01082 0.622
MOD_Cter_Amidation 167 170 PF01082 0.574
MOD_GlcNHglycan 124 127 PF01048 0.621
MOD_GlcNHglycan 132 135 PF01048 0.563
MOD_GlcNHglycan 265 268 PF01048 0.748
MOD_GlcNHglycan 30 33 PF01048 0.623
MOD_GlcNHglycan 309 312 PF01048 0.665
MOD_GlcNHglycan 49 52 PF01048 0.698
MOD_GlcNHglycan 60 63 PF01048 0.560
MOD_GSK3_1 122 129 PF00069 0.653
MOD_GSK3_1 173 180 PF00069 0.570
MOD_GSK3_1 259 266 PF00069 0.636
MOD_GSK3_1 303 310 PF00069 0.699
MOD_GSK3_1 54 61 PF00069 0.765
MOD_GSK3_1 65 72 PF00069 0.555
MOD_GSK3_1 77 84 PF00069 0.544
MOD_GSK3_1 87 94 PF00069 0.586
MOD_LATS_1 301 307 PF00433 0.563
MOD_N-GLC_1 211 216 PF02516 0.639
MOD_N-GLC_1 304 309 PF02516 0.561
MOD_N-GLC_1 327 332 PF02516 0.640
MOD_NEK2_1 18 23 PF00069 0.597
MOD_NEK2_1 365 370 PF00069 0.534
MOD_NEK2_1 60 65 PF00069 0.740
MOD_NEK2_1 77 82 PF00069 0.498
MOD_PIKK_1 18 24 PF00454 0.574
MOD_PIKK_1 200 206 PF00454 0.594
MOD_PIKK_1 327 333 PF00454 0.637
MOD_PIKK_1 77 83 PF00454 0.572
MOD_PKA_2 343 349 PF00069 0.514
MOD_Plk_1 249 255 PF00069 0.539
MOD_Plk_1 304 310 PF00069 0.565
MOD_Plk_1 327 333 PF00069 0.637
MOD_Plk_1 87 93 PF00069 0.587
MOD_Plk_4 254 260 PF00069 0.664
MOD_Plk_4 304 310 PF00069 0.593
MOD_Plk_4 36 42 PF00069 0.525
MOD_ProDKin_1 65 71 PF00069 0.713
MOD_ProDKin_1 81 87 PF00069 0.572
MOD_ProDKin_1 92 98 PF00069 0.596
MOD_SUMO_rev_2 15 21 PF00179 0.572
TRG_ER_diArg_1 188 190 PF00400 0.582
TRG_ER_diArg_1 205 208 PF00400 0.600
TRG_ER_diArg_1 227 229 PF00400 0.481
TRG_ER_diArg_1 8 11 PF00400 0.561
TRG_ER_diArg_1 99 102 PF00400 0.620

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I155 Leptomonas seymouri 45% 100%
A4H774 Leishmania braziliensis 70% 95%
A4HVL4 Leishmania infantum 99% 100%
E9APB0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QG68 Leishmania major 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS