LeishMANIAdb
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RNA binding protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RNA binding protein, putative
Gene product:
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), putative
Species:
Leishmania donovani
UniProt:
A0A3Q8I7R0_LEIDO
TriTrypDb:
LdBPK_100750.1 , LdCL_100014300 , LDHU3_10.1080
Length:
952

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005634 nucleus 5 1
GO:0005654 nucleoplasm 2 1
GO:0005730 nucleolus 5 1
GO:0005737 cytoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
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Expansion

Sequence features

A0A3Q8I7R0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I7R0

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 12
GO:0003723 RNA binding 4 12
GO:0003729 mRNA binding 5 1
GO:0005488 binding 1 12
GO:0097159 organic cyclic compound binding 2 12
GO:1901363 heterocyclic compound binding 2 12
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 190 194 PF00656 0.682
CLV_C14_Caspase3-7 302 306 PF00656 0.736
CLV_C14_Caspase3-7 321 325 PF00656 0.770
CLV_C14_Caspase3-7 593 597 PF00656 0.552
CLV_MEL_PAP_1 603 609 PF00089 0.506
CLV_NRD_NRD_1 125 127 PF00675 0.594
CLV_NRD_NRD_1 137 139 PF00675 0.667
CLV_NRD_NRD_1 169 171 PF00675 0.756
CLV_NRD_NRD_1 197 199 PF00675 0.541
CLV_NRD_NRD_1 250 252 PF00675 0.699
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HY42 Leptomonas seymouri 66% 100%
A0A0S4J8G6 Bodo saltans 40% 100%
A0A1X0NQT4 Trypanosomatidae 47% 100%
A0A3R7NQE9 Trypanosoma rangeli 48% 100%
A4H661 Leishmania braziliensis 80% 99%
A4HUI2 Leishmania infantum 99% 100%
C9ZVK7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 100%
E9AN80 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q06106 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 24% 100%
Q4QHE5 Leishmania major 92% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS