Histone h1-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

histone h1-like protein

Species:

Leishmania donovani

UniProt:

A0A3Q8I7H5_LEIDO

TriTrypDb:

LdBPK_090930.1 , LdCL_090014700 , LDHU3_09.1080

Length:

490

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 2, no: 4
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3Q8I7H5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3Q8I7H5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	241	245	PF00656	0.452
CLV_NRD_NRD_1	159	161	PF00675	0.790
CLV_NRD_NRD_1	170	172	PF00675	0.528
CLV_NRD_NRD_1	178	180	PF00675	0.366
CLV_NRD_NRD_1	247	249	PF00675	0.557
CLV_NRD_NRD_1	363	365	PF00675	0.674
CLV_NRD_NRD_1	427	429	PF00675	0.777
CLV_NRD_NRD_1	441	443	PF00675	0.694
CLV_NRD_NRD_1	472	474	PF00675	0.714
CLV_PCSK_KEX2_1	159	161	PF00082	0.790
CLV_PCSK_KEX2_1	170	172	PF00082	0.528
CLV_PCSK_KEX2_1	178	180	PF00082	0.366
CLV_PCSK_KEX2_1	247	249	PF00082	0.560
CLV_PCSK_KEX2_1	340	342	PF00082	0.574
CLV_PCSK_KEX2_1	363	365	PF00082	0.643
CLV_PCSK_KEX2_1	374	376	PF00082	0.618
CLV_PCSK_KEX2_1	427	429	PF00082	0.603
CLV_PCSK_KEX2_1	479	481	PF00082	0.639
CLV_PCSK_KEX2_1	485	487	PF00082	0.595
CLV_PCSK_PC1ET2_1	340	342	PF00082	0.591
CLV_PCSK_PC1ET2_1	374	376	PF00082	0.636
CLV_PCSK_PC1ET2_1	479	481	PF00082	0.639
CLV_PCSK_PC1ET2_1	485	487	PF00082	0.595
CLV_PCSK_SKI1_1	3	7	PF00082	0.540
CLV_PCSK_SKI1_1	442	446	PF00082	0.691
DEG_Nend_Nbox_1	1	3	PF02207	0.557
DEG_SPOP_SBC_1	142	146	PF00917	0.541
DEG_SPOP_SBC_1	451	455	PF00917	0.574
DOC_CYCLIN_yCln2_LP_2	297	303	PF00134	0.643
DOC_PP2B_LxvP_1	297	300	PF13499	0.641
DOC_USP7_MATH_1	123	127	PF00917	0.712
DOC_USP7_MATH_1	142	146	PF00917	0.754
DOC_USP7_MATH_1	271	275	PF00917	0.604
DOC_USP7_MATH_1	368	372	PF00917	0.712
DOC_USP7_MATH_1	39	43	PF00917	0.694
DOC_USP7_MATH_1	468	472	PF00917	0.777
DOC_USP7_UBL2_3	320	324	PF12436	0.614
DOC_USP7_UBL2_3	397	401	PF12436	0.647
DOC_USP7_UBL2_3	430	434	PF12436	0.623
DOC_USP7_UBL2_3	439	443	PF12436	0.641
DOC_USP7_UBL2_3	446	450	PF12436	0.594
DOC_USP7_UBL2_3	474	478	PF12436	0.633
DOC_WW_Pin1_4	195	200	PF00397	0.492
DOC_WW_Pin1_4	354	359	PF00397	0.602
DOC_WW_Pin1_4	411	416	PF00397	0.627
DOC_WW_Pin1_4	466	471	PF00397	0.572
LIG_14-3-3_CanoR_1	236	243	PF00244	0.412
LIG_14-3-3_CanoR_1	327	335	PF00244	0.672
LIG_14-3-3_CanoR_1	409	415	PF00244	0.551
LIG_14-3-3_CanoR_1	452	460	PF00244	0.703
LIG_14-3-3_CanoR_1	473	481	PF00244	0.640
LIG_Clathr_ClatBox_1	82	86	PF01394	0.630
LIG_FHA_1	199	205	PF00498	0.471
LIG_FHA_2	236	242	PF00498	0.517
LIG_FHA_2	288	294	PF00498	0.649
LIG_FHA_2	72	78	PF00498	0.548
LIG_LIR_Nem_3	93	99	PF02991	0.594
LIG_NRP_CendR_1	489	490	PF00754	0.693
LIG_Pex14_2	100	104	PF04695	0.531
LIG_Pex14_2	16	20	PF04695	0.600
LIG_RPA_C_Fungi	423	435	PF08784	0.572
LIG_SH2_STAT5	96	99	PF00017	0.582
LIG_SH3_1	401	407	PF00018	0.611
LIG_SH3_2	404	409	PF14604	0.613
LIG_SH3_3	193	199	PF00018	0.502
LIG_SH3_3	362	368	PF00018	0.735
LIG_SH3_3	401	407	PF00018	0.574
LIG_SH3_3	445	451	PF00018	0.663
LIG_SH3_4	439	446	PF00018	0.706
LIG_SUMO_SIM_anti_2	111	118	PF11976	0.603
LIG_SUMO_SIM_par_1	81	88	PF11976	0.626
LIG_WRC_WIRS_1	17	22	PF05994	0.503
MOD_CDK_SPK_2	354	359	PF00069	0.650
MOD_CDK_SPxxK_3	466	473	PF00069	0.573
MOD_CK1_1	143	149	PF00069	0.758
MOD_CK1_1	18	24	PF00069	0.570
MOD_CK1_1	184	190	PF00069	0.590
MOD_CK1_1	195	201	PF00069	0.532
MOD_CK1_1	276	282	PF00069	0.732
MOD_CK1_1	31	37	PF00069	0.686
MOD_CK1_1	357	363	PF00069	0.579
MOD_CK2_1	141	147	PF00069	0.543
MOD_CK2_1	235	241	PF00069	0.441
MOD_CK2_1	287	293	PF00069	0.654
MOD_GlcNHglycan	117	120	PF01048	0.644
MOD_GlcNHglycan	183	186	PF01048	0.598
MOD_GlcNHglycan	21	24	PF01048	0.641
MOD_GlcNHglycan	278	281	PF01048	0.773
MOD_GlcNHglycan	30	33	PF01048	0.678
MOD_GlcNHglycan	324	327	PF01048	0.663
MOD_GlcNHglycan	336	339	PF01048	0.585
MOD_GlcNHglycan	41	44	PF01048	0.452
MOD_GlcNHglycan	470	473	PF01048	0.604
MOD_GlcNHglycan	90	93	PF01048	0.557
MOD_GSK3_1	141	148	PF00069	0.623
MOD_GSK3_1	15	22	PF00069	0.602
MOD_GSK3_1	231	238	PF00069	0.519
MOD_GSK3_1	322	329	PF00069	0.668
MOD_GSK3_1	34	41	PF00069	0.641
MOD_GSK3_1	370	377	PF00069	0.779
MOD_GSK3_1	438	445	PF00069	0.627
MOD_GSK3_1	446	453	PF00069	0.689
MOD_GSK3_1	468	475	PF00069	0.584
MOD_GSK3_1	67	74	PF00069	0.605
MOD_N-GLC_1	219	224	PF02516	0.433
MOD_N-GLC_1	354	359	PF02516	0.638
MOD_N-GLC_1	88	93	PF02516	0.594
MOD_NEK2_1	16	21	PF00069	0.674
MOD_NEK2_1	203	208	PF00069	0.477
MOD_NEK2_1	219	224	PF00069	0.433
MOD_NEK2_1	410	415	PF00069	0.549
MOD_NEK2_1	49	54	PF00069	0.629
MOD_NEK2_2	58	63	PF00069	0.766
MOD_PIKK_1	184	190	PF00454	0.484
MOD_PIKK_1	203	209	PF00454	0.625
MOD_PIKK_1	265	271	PF00454	0.609
MOD_PIKK_1	273	279	PF00454	0.585
MOD_PIKK_1	49	55	PF00454	0.650
MOD_PIKK_1	61	67	PF00454	0.524
MOD_PK_1	456	462	PF00069	0.672
MOD_PKA_1	374	380	PF00069	0.657
MOD_PKA_1	442	448	PF00069	0.699
MOD_PKA_1	479	485	PF00069	0.583
MOD_PKA_2	235	241	PF00069	0.434
MOD_PKA_2	326	332	PF00069	0.669
MOD_PKA_2	374	380	PF00069	0.716
MOD_PKA_2	451	457	PF00069	0.673
MOD_PKA_2	472	478	PF00069	0.704
MOD_PKA_2	479	485	PF00069	0.590
MOD_PKA_2	6	12	PF00069	0.613
MOD_PKB_1	179	187	PF00069	0.554
MOD_Plk_1	110	116	PF00069	0.653
MOD_Plk_1	219	225	PF00069	0.435
MOD_Plk_4	110	116	PF00069	0.653
MOD_Plk_4	287	293	PF00069	0.654
MOD_Plk_4	331	337	PF00069	0.578
MOD_Plk_4	43	49	PF00069	0.596
MOD_ProDKin_1	195	201	PF00069	0.485
MOD_ProDKin_1	354	360	PF00069	0.601
MOD_ProDKin_1	411	417	PF00069	0.629
MOD_ProDKin_1	466	472	PF00069	0.572
MOD_SUMO_for_1	226	229	PF00179	0.435
TRG_ER_diArg_1	170	172	PF00400	0.581
TRG_ER_diArg_1	178	181	PF00400	0.433
TRG_ER_diArg_1	246	248	PF00400	0.571
TRG_ER_diArg_1	341	344	PF00400	0.688
TRG_ER_diArg_1	363	365	PF00400	0.608
TRG_ER_diArg_1	460	463	PF00400	0.608
TRG_NLS_MonoExtC_3	338	343	PF00514	0.544
TRG_NLS_MonoExtN_4	339	344	PF00514	0.533
TRG_Pf-PMV_PEXEL_1	107	111	PF00026	0.580

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILW1	Leptomonas seymouri	44%	95%
A4H5N7	Leishmania braziliensis	65%	100%
A4HU09	Leishmania infantum	100%	100%
E9AMT9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	99%
Q4QHT6	Leishmania major	89%	99%