ATP-dependent Clp protease subunit, heat shock protein 78 (HSP78)

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Heat shock protein 100 kDa

Species:

Leishmania infantum

UniProt:

A0A381MP32_LEIIN

TriTrypDb:

LINF_020012400

Length:

817

Annotations

Annotations by Jardim et al.

Proteases, ATP-dependent Clp protease subunit, heat shock 78 (HSP78)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A381MP32

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A381MP32

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	9
GO:0006807	nitrogen compound metabolic process	2	9
GO:0008152	metabolic process	1	9
GO:0019538	protein metabolic process	3	9
GO:0043170	macromolecule metabolic process	3	9
GO:0044238	primary metabolic process	2	9
GO:0071704	organic substance metabolic process	2	9
GO:1901564	organonitrogen compound metabolic process	3	9
GO:0006950	response to stress	2	1
GO:0009266	response to temperature stimulus	3	1
GO:0009408	response to heat	3	1
GO:0009628	response to abiotic stimulus	2	1
GO:0009987	cellular process	1	1
GO:0033554	cellular response to stress	3	1
GO:0034605	cellular response to heat	4	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	13
GO:0003824	catalytic activity	1	13
GO:0005488	binding	1	13
GO:0005524	ATP binding	5	13
GO:0008233	peptidase activity	3	9
GO:0016462	pyrophosphatase activity	5	13
GO:0016787	hydrolase activity	2	13
GO:0016817	hydrolase activity, acting on acid anhydrides	3	13
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	13
GO:0016887	ATP hydrolysis activity	7	13
GO:0017076	purine nucleotide binding	4	13
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	13
GO:0030554	adenyl nucleotide binding	5	13
GO:0032553	ribonucleotide binding	3	13
GO:0032555	purine ribonucleotide binding	4	13
GO:0032559	adenyl ribonucleotide binding	5	13
GO:0035639	purine ribonucleoside triphosphate binding	4	13
GO:0036094	small molecule binding	2	13
GO:0043167	ion binding	2	13
GO:0043168	anion binding	3	13
GO:0097159	organic cyclic compound binding	2	13
GO:0097367	carbohydrate derivative binding	2	13
GO:0140096	catalytic activity, acting on a protein	2	9
GO:1901265	nucleoside phosphate binding	3	13
GO:1901363	heterocyclic compound binding	2	13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	229	233	PF00656	0.377
CLV_C14_Caspase3-7	789	793	PF00656	0.500
CLV_NRD_NRD_1	129	131	PF00675	0.390
CLV_NRD_NRD_1	137	139	PF00675	0.440
CLV_NRD_NRD_1	273	275	PF00675	0.336
CLV_NRD_NRD_1	326	328	PF00675	0.274
CLV_NRD_NRD_1	33	35	PF00675	0.658
CLV_NRD_NRD_1	4	6	PF00675	0.614
CLV_NRD_NRD_1	610	612	PF00675	0.233
CLV_NRD_NRD_1	647	649	PF00675	0.233
CLV_PCSK_KEX2_1	129	131	PF00082	0.385
CLV_PCSK_KEX2_1	137	139	PF00082	0.423
CLV_PCSK_KEX2_1	273	275	PF00082	0.321
CLV_PCSK_KEX2_1	3	5	PF00082	0.646
CLV_PCSK_KEX2_1	326	328	PF00082	0.276
CLV_PCSK_KEX2_1	537	539	PF00082	0.285
CLV_PCSK_KEX2_1	609	611	PF00082	0.233
CLV_PCSK_KEX2_1	647	649	PF00082	0.231
CLV_PCSK_KEX2_1	760	762	PF00082	0.281
CLV_PCSK_PC1ET2_1	537	539	PF00082	0.285
CLV_PCSK_PC1ET2_1	760	762	PF00082	0.281
CLV_PCSK_SKI1_1	107	111	PF00082	0.376
CLV_PCSK_SKI1_1	163	167	PF00082	0.341
CLV_PCSK_SKI1_1	201	205	PF00082	0.278
CLV_PCSK_SKI1_1	213	217	PF00082	0.256
CLV_PCSK_SKI1_1	293	297	PF00082	0.285
CLV_PCSK_SKI1_1	408	412	PF00082	0.399
CLV_PCSK_SKI1_1	562	566	PF00082	0.233
CLV_PCSK_SKI1_1	726	730	PF00082	0.343
CLV_PCSK_SKI1_1	757	761	PF00082	0.281
CLV_Separin_Metazoa	784	788	PF03568	0.220
DEG_APCC_DBOX_1	246	254	PF00400	0.285
DEG_APCC_DBOX_1	497	505	PF00400	0.414
DEG_Nend_Nbox_1	1	3	PF02207	0.622
DEG_ODPH_VHL_1	691	704	PF01847	0.488
DEG_SCF_FBW7_1	67	72	PF00400	0.697
DOC_CYCLIN_RxL_1	403	413	PF00134	0.538
DOC_CYCLIN_RxL_1	558	569	PF00134	0.433
DOC_CYCLIN_yCln2_LP_2	21	27	PF00134	0.614
DOC_MAPK_gen_1	137	146	PF00069	0.390
DOC_MAPK_gen_1	273	280	PF00069	0.285
DOC_MAPK_gen_1	415	423	PF00069	0.398
DOC_MAPK_gen_1	609	618	PF00069	0.433
DOC_MAPK_gen_1	779	788	PF00069	0.281
DOC_MAPK_JIP1_4	350	356	PF00069	0.406
DOC_MAPK_MEF2A_6	359	366	PF00069	0.285
DOC_MAPK_MEF2A_6	714	721	PF00069	0.261
DOC_MAPK_MEF2A_6	781	790	PF00069	0.281
DOC_MAPK_NFAT4_5	359	367	PF00069	0.406
DOC_PP1_RVXF_1	211	218	PF00149	0.276
DOC_PP1_RVXF_1	645	652	PF00149	0.433
DOC_PP1_SILK_1	289	294	PF00149	0.406
DOC_PP2B_LxvP_1	21	24	PF13499	0.609
DOC_PP4_FxxP_1	545	548	PF00568	0.433
DOC_USP7_MATH_1	227	231	PF00917	0.285
DOC_USP7_MATH_1	316	320	PF00917	0.285
DOC_USP7_MATH_1	431	435	PF00917	0.452
DOC_USP7_MATH_1	45	49	PF00917	0.658
DOC_USP7_MATH_1	518	522	PF00917	0.364
DOC_USP7_MATH_1	539	543	PF00917	0.428
DOC_USP7_MATH_1	624	628	PF00917	0.432
DOC_USP7_MATH_1	69	73	PF00917	0.663
DOC_USP7_UBL2_3	201	205	PF12436	0.285
DOC_USP7_UBL2_3	453	457	PF12436	0.470
DOC_USP7_UBL2_3	558	562	PF12436	0.444
DOC_WW_Pin1_4	41	46	PF00397	0.596
DOC_WW_Pin1_4	65	70	PF00397	0.630
DOC_WW_Pin1_4	801	806	PF00397	0.563
LIG_14-3-3_CanoR_1	14	24	PF00244	0.650
LIG_14-3-3_CanoR_1	273	279	PF00244	0.278
LIG_14-3-3_CanoR_1	321	329	PF00244	0.285
LIG_14-3-3_CanoR_1	34	41	PF00244	0.426
LIG_14-3-3_CanoR_1	582	586	PF00244	0.451
LIG_14-3-3_CanoR_1	61	70	PF00244	0.558
LIG_14-3-3_CanoR_1	761	771	PF00244	0.281
LIG_14-3-3_CanoR_1	787	791	PF00244	0.404
LIG_APCC_ABBA_1	214	219	PF00400	0.285
LIG_APCC_ABBA_1	615	620	PF00400	0.433
LIG_APCC_ABBAyCdc20_2	213	219	PF00400	0.285
LIG_BRCT_BRCA1_1	433	437	PF00533	0.559
LIG_BRCT_BRCA1_1	463	467	PF00533	0.562
LIG_BRCT_BRCA1_1	541	545	PF00533	0.418
LIG_BRCT_BRCA1_2	433	439	PF00533	0.559
LIG_Clathr_ClatBox_1	501	505	PF01394	0.393
LIG_Clathr_ClatBox_1	773	777	PF01394	0.316
LIG_deltaCOP1_diTrp_1	401	411	PF00928	0.395
LIG_EH1_1	582	590	PF00400	0.433
LIG_EVH1_2	97	101	PF00568	0.437
LIG_FHA_1	129	135	PF00498	0.350
LIG_FHA_1	152	158	PF00498	0.285
LIG_FHA_1	16	22	PF00498	0.595
LIG_FHA_1	286	292	PF00498	0.285
LIG_FHA_1	416	422	PF00498	0.395
LIG_FHA_1	521	527	PF00498	0.362
LIG_FHA_1	603	609	PF00498	0.433
LIG_FHA_1	652	658	PF00498	0.426
LIG_FHA_2	254	260	PF00498	0.284
LIG_FHA_2	282	288	PF00498	0.285
LIG_FHA_2	472	478	PF00498	0.479
LIG_FHA_2	732	738	PF00498	0.396
LIG_LIR_Apic_2	542	548	PF02991	0.421
LIG_LIR_Apic_2	89	93	PF02991	0.639
LIG_LIR_Gen_1	396	402	PF02991	0.423
LIG_LIR_Gen_1	542	551	PF02991	0.428
LIG_LIR_Gen_1	718	728	PF02991	0.261
LIG_LIR_Gen_1	739	750	PF02991	0.285
LIG_LIR_Nem_3	384	390	PF02991	0.398
LIG_LIR_Nem_3	396	400	PF02991	0.382
LIG_LIR_Nem_3	542	546	PF02991	0.428
LIG_LIR_Nem_3	718	724	PF02991	0.261
LIG_LIR_Nem_3	739	745	PF02991	0.273
LIG_Pex14_2	192	196	PF04695	0.342
LIG_RPA_C_Fungi	316	328	PF08784	0.285
LIG_SH2_CRK	314	318	PF00017	0.285
LIG_SH2_CRK	613	617	PF00017	0.285
LIG_SH2_CRK	750	754	PF00017	0.281
LIG_SH2_NCK_1	314	318	PF00017	0.285
LIG_SH2_NCK_1	387	391	PF00017	0.432
LIG_SH2_NCK_1	750	754	PF00017	0.281
LIG_SH2_SRC	598	601	PF00017	0.285
LIG_SH2_SRC	613	616	PF00017	0.285
LIG_SH2_STAP1	105	109	PF00017	0.379
LIG_SH2_STAP1	179	183	PF00017	0.370
LIG_SH2_STAP1	750	754	PF00017	0.353
LIG_SH2_STAT5	322	325	PF00017	0.282
LIG_SH2_STAT5	595	598	PF00017	0.285
LIG_SH3_3	21	27	PF00018	0.691
LIG_SH3_3	277	283	PF00018	0.362
LIG_SUMO_SIM_anti_2	286	293	PF11976	0.285
LIG_SUMO_SIM_anti_2	352	358	PF11976	0.406
LIG_SUMO_SIM_anti_2	418	425	PF11976	0.416
LIG_SUMO_SIM_anti_2	654	660	PF11976	0.285
LIG_SUMO_SIM_anti_2	715	721	PF11976	0.323
LIG_SUMO_SIM_par_1	142	148	PF11976	0.285
LIG_SUMO_SIM_par_1	653	660	PF11976	0.285
LIG_SxIP_EBH_1	484	494	PF03271	0.445
LIG_TRAF2_1	284	287	PF00917	0.285
LIG_TRAF2_1	399	402	PF00917	0.508
LIG_TRAF2_1	734	737	PF00917	0.388
LIG_TYR_ITAM	384	400	PF00017	0.413
LIG_TYR_ITIM	312	317	PF00017	0.285
LIG_UBA3_1	291	298	PF00899	0.396
LIG_UBA3_1	361	365	PF00899	0.370
LIG_UBA3_1	410	415	PF00899	0.387
LIG_UBA3_1	451	459	PF00899	0.526
LIG_UBA3_1	501	509	PF00899	0.449
LIG_WRC_WIRS_1	540	545	PF05994	0.277
LIG_WW_1	592	595	PF00397	0.285
MOD_CDC14_SPxK_1	804	807	PF00782	0.631
MOD_CDK_SPxK_1	801	807	PF00069	0.607
MOD_CK1_1	136	142	PF00069	0.411
MOD_CK1_1	472	478	PF00069	0.410
MOD_CK1_1	73	79	PF00069	0.677
MOD_CK2_1	254	260	PF00069	0.285
MOD_CK2_1	281	287	PF00069	0.285
MOD_CK2_1	346	352	PF00069	0.285
MOD_CK2_1	493	499	PF00069	0.587
MOD_CK2_1	712	718	PF00069	0.326
MOD_CK2_1	731	737	PF00069	0.327
MOD_Cter_Amidation	645	648	PF01082	0.285
MOD_GlcNHglycan	229	232	PF01048	0.285
MOD_GlcNHglycan	433	436	PF01048	0.523
MOD_GlcNHglycan	677	680	PF01048	0.362
MOD_GlcNHglycan	72	75	PF01048	0.657
MOD_GlcNHglycan	750	753	PF01048	0.354
MOD_GSK3_1	227	234	PF00069	0.285
MOD_GSK3_1	274	281	PF00069	0.285
MOD_GSK3_1	41	48	PF00069	0.612
MOD_GSK3_1	52	59	PF00069	0.637
MOD_GSK3_1	61	68	PF00069	0.727
MOD_GSK3_1	69	76	PF00069	0.618
MOD_GSK3_1	731	738	PF00069	0.405
MOD_N-GLC_1	70	75	PF02516	0.684
MOD_N-GLC_1	731	736	PF02516	0.402
MOD_NEK2_1	204	209	PF00069	0.417
MOD_NEK2_1	410	415	PF00069	0.529
MOD_NEK2_1	46	51	PF00069	0.653
MOD_NEK2_1	461	466	PF00069	0.586
MOD_NEK2_1	508	513	PF00069	0.503
MOD_NEK2_1	56	61	PF00069	0.524
MOD_NEK2_1	604	609	PF00069	0.285
MOD_NEK2_1	641	646	PF00069	0.271
MOD_NEK2_1	651	656	PF00069	0.271
MOD_PIKK_1	388	394	PF00454	0.482
MOD_PIKK_1	443	449	PF00454	0.513
MOD_PK_1	274	280	PF00069	0.285
MOD_PKA_2	128	134	PF00069	0.377
MOD_PKA_2	136	142	PF00069	0.411
MOD_PKA_2	33	39	PF00069	0.598
MOD_PKA_2	483	489	PF00069	0.390
MOD_PKA_2	526	532	PF00069	0.394
MOD_PKA_2	56	62	PF00069	0.733
MOD_PKA_2	581	587	PF00069	0.310
MOD_PKA_2	706	712	PF00069	0.370
MOD_PKA_2	786	792	PF00069	0.436
MOD_Plk_1	285	291	PF00069	0.285
MOD_Plk_1	566	572	PF00069	0.285
MOD_Plk_1	731	737	PF00069	0.319
MOD_Plk_2-3	712	718	PF00069	0.323
MOD_Plk_4	182	188	PF00069	0.285
MOD_Plk_4	220	226	PF00069	0.285
MOD_Plk_4	274	280	PF00069	0.278
MOD_Plk_4	508	514	PF00069	0.503
MOD_Plk_4	539	545	PF00069	0.277
MOD_Plk_4	566	572	PF00069	0.280
MOD_Plk_4	651	657	PF00069	0.285
MOD_ProDKin_1	41	47	PF00069	0.594
MOD_ProDKin_1	65	71	PF00069	0.633
MOD_ProDKin_1	801	807	PF00069	0.574
MOD_SUMO_for_1	165	168	PF00179	0.370
MOD_SUMO_for_1	307	310	PF00179	0.285
MOD_SUMO_for_1	364	367	PF00179	0.285
MOD_SUMO_rev_2	505	511	PF00179	0.517
MOD_SUMO_rev_2	644	654	PF00179	0.285
TRG_DiLeu_BaEn_1	220	225	PF01217	0.278
TRG_DiLeu_BaEn_1	352	357	PF01217	0.406
TRG_DiLeu_BaEn_1	497	502	PF01217	0.427
TRG_DiLeu_BaEn_3	286	292	PF01217	0.406
TRG_DiLeu_BaEn_4	419	425	PF01217	0.522
TRG_DiLeu_BaEn_4	599	605	PF01217	0.285
TRG_DiLeu_BaLyEn_6	584	589	PF01217	0.285
TRG_DiLeu_BaLyEn_6	810	815	PF01217	0.624
TRG_ENDOCYTIC_2	314	317	PF00928	0.281
TRG_ENDOCYTIC_2	387	390	PF00928	0.405
TRG_ENDOCYTIC_2	397	400	PF00928	0.373
TRG_ENDOCYTIC_2	613	616	PF00928	0.285
TRG_ENDOCYTIC_2	742	745	PF00928	0.293
TRG_ENDOCYTIC_2	750	753	PF00928	0.231
TRG_ER_diArg_1	128	130	PF00400	0.387
TRG_ER_diArg_1	2	5	PF00400	0.645
TRG_ER_diArg_1	273	275	PF00400	0.315
TRG_ER_diArg_1	326	328	PF00400	0.276
TRG_ER_diArg_1	342	345	PF00400	0.285
TRG_ER_diArg_1	608	611	PF00400	0.285
TRG_ER_diArg_1	647	649	PF00400	0.285
TRG_ER_diArg_1	687	690	PF00400	0.370
TRG_LysEnd_GGAAcLL_1	811	817	PF00790	0.693
TRG_NES_CRM1_1	355	369	PF08389	0.406
TRG_NES_CRM1_1	766	777	PF08389	0.347
TRG_Pf-PMV_PEXEL_1	107	111	PF00026	0.376
TRG_Pf-PMV_PEXEL_1	293	297	PF00026	0.265
TRG_Pf-PMV_PEXEL_1	321	325	PF00026	0.285
TRG_Pf-PMV_PEXEL_1	326	330	PF00026	0.285
TRG_Pf-PMV_PEXEL_1	4	8	PF00026	0.698
TRG_Pf-PMV_PEXEL_1	714	718	PF00026	0.269
TRG_Pf-PMV_PEXEL_1	726	730	PF00026	0.305
TRG_Pf-PMV_PEXEL_1	813	817	PF00026	0.697

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9X7	Leptomonas seymouri	90%	100%
A0A0N1PC62	Leptomonas seymouri	50%	94%
A0A0S4J5R1	Bodo saltans	49%	100%
A0A0S4KJV7	Bodo saltans	83%	100%
A0A1X0NJK9	Trypanosomatidae	78%	100%
A0A1X0NRE7	Trypanosomatidae	51%	94%
A0A3R7LKM0	Trypanosoma rangeli	51%	94%
A0A3S5H516	Leishmania donovani	100%	100%
A0A3S7X129	Leishmania donovani	100%	100%
A0A3S7X2C6	Leishmania donovani	49%	94%
A0A422NAZ4	Trypanosoma rangeli	81%	100%
A0R574	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	47%	96%
A4HG34	Leishmania braziliensis	93%	100%
A4HHD8	Leishmania braziliensis	51%	100%
A4I4I4	Leishmania infantum	49%	94%
C9ZJ56	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
C9ZJT4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	94%
E9ACE5	Leishmania major	98%	100%
E9ADY5	Leishmania major	51%	100%
E9AJN3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
E9ALU6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
G2K265	Listeria monocytogenes serotype 1/2a (strain 10403S)	53%	94%
O31673	Bacillus subtilis (strain 168)	44%	100%
O34209	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	51%	91%
O67588	Aquifex aeolicus (strain VF5)	46%	81%
O68185	Lactococcus lactis subsp. cremoris (strain MG1363)	54%	94%
O74402	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	52%	100%
O78410	Guillardia theta	46%	100%
O83110	Treponema pallidum (strain Nichols)	53%	93%
O84115	Chlamydia trachomatis (strain D/UW-3/Cx)	51%	94%
O84288	Chlamydia trachomatis (strain D/UW-3/Cx)	44%	96%
O87444	Leptolyngbya boryana	52%	94%
O94641	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	90%
P0A523	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	47%	96%
P0C281	Staphylococcus aureus (strain COL)	47%	100%
P17422	Dichelobacter nodosus	54%	95%
P24428	Mycobacterium leprae (strain TN)	47%	96%
P31539	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	90%
P31540	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	88%
P31541	Solanum lycopersicum	45%	88%
P31542	Solanum lycopersicum	46%	89%
P31543	Trypanosoma brucei brucei	50%	94%
P33416	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	100%
P35100	Pisum sativum	46%	89%
P35594	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	44%	100%
P37571	Bacillus subtilis (strain 168)	45%	100%
P42730	Arabidopsis thaliana	50%	90%
P42762	Arabidopsis thaliana	41%	86%
P44403	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	56%	95%
P46523	Brassica napus	44%	93%
P47597	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	45%	100%
P49574	Trieres chinensis	42%	92%
P51332	Porphyra purpurea	45%	100%
P53532	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	53%	96%
P53533	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	54%	93%
P63284	Escherichia coli (strain K12)	58%	95%
P63285	Escherichia coli O157:H7	58%	95%
P63286	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	58%	95%
P63287	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	55%	96%
P71404	Helicobacter pylori (strain ATCC 700392 / 26695)	49%	95%
P74361	Synechocystis sp. (strain PCC 6803 / Kazusa)	53%	94%
P74459	Synechocystis sp. (strain PCC 6803 / Kazusa)	52%	91%
P75247	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	46%	100%
P9WPC8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	47%	96%
P9WPC9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	47%	96%
P9WPD0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	55%	96%
P9WPD1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	55%	96%
Q06716	Lactococcus lactis subsp. lactis	40%	100%
Q0E3C8	Oryza sativa subsp. japonica	51%	83%
Q1RGR1	Rickettsia bellii (strain RML369-C)	57%	95%
Q1XDF4	Neopyropia yezoensis	47%	100%
Q2FDV8	Staphylococcus aureus (strain USA300)	40%	100%
Q2FJB5	Staphylococcus aureus (strain USA300)	47%	100%
Q2FV74	Staphylococcus aureus (strain NCTC 8325 / PS 47)	40%	100%
Q2G0P5	Staphylococcus aureus (strain NCTC 8325 / PS 47)	47%	100%
Q2QVG9	Oryza sativa subsp. japonica	46%	89%
Q2YSD6	Staphylococcus aureus (strain bovine RF122 / ET3-1)	47%	100%
Q2YWB1	Staphylococcus aureus (strain bovine RF122 / ET3-1)	38%	100%
Q49V34	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	48%	100%
Q4L3I4	Staphylococcus haemolyticus (strain JCSC1435)	47%	99%
Q4UN57	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	55%	95%
Q53LY0	Oryza sativa subsp. japonica	44%	88%
Q53N47	Oryza sativa subsp. japonica	42%	89%
Q54316	Brachyspira hyodysenteriae	44%	99%
Q5HD02	Staphylococcus aureus (strain COL)	40%	100%
Q5HHB0	Staphylococcus aureus (strain COL)	52%	94%
Q5HQI5	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	50%	94%
Q5HRM8	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	46%	100%
Q5XCL7	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	39%	100%
Q68XR2	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	54%	95%
Q6F2Y7	Oryza sativa subsp. japonica	51%	90%
Q6G6C6	Staphylococcus aureus (strain MSSA476)	40%	100%
Q6GAV1	Staphylococcus aureus (strain MSSA476)	52%	94%
Q6GBW3	Staphylococcus aureus (strain MSSA476)	47%	100%
Q6GDQ0	Staphylococcus aureus (strain MRSA252)	38%	100%
Q6GIB2	Staphylococcus aureus (strain MRSA252)	52%	94%
Q6GJE4	Staphylococcus aureus (strain MRSA252)	47%	100%
Q6H795	Oryza sativa subsp. japonica	42%	87%
Q6LMY0	Photobacterium profundum (strain SS9)	55%	95%
Q6MD97	Protochlamydia amoebophila (strain UWE25)	51%	94%
Q6MIV0	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	55%	96%
Q6N1H2	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	55%	93%
Q6NF05	Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)	53%	96%
Q71XF9	Listeria monocytogenes serotype 4b (strain F2365)	53%	94%
Q72AW6	Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough)	53%	94%
Q72IK9	Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)	55%	96%
Q72QU2	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	51%	95%
Q73BY1	Bacillus cereus (strain ATCC 10987 / NRS 248)	52%	94%
Q73IE4	Wolbachia pipientis wMel	54%	96%
Q73K92	Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)	53%	95%
Q73T66	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	54%	96%
Q74FF1	Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)	54%	94%
Q74X11	Yersinia pestis	57%	95%
Q75GT3	Oryza sativa subsp. japonica	51%	84%
Q7A3F4	Staphylococcus aureus (strain N315)	40%	100%
Q7A6G6	Staphylococcus aureus (strain N315)	52%	94%
Q7A797	Staphylococcus aureus (strain N315)	47%	100%
Q7AJA9	Chlamydia pneumoniae	49%	94%
Q7AMH5	Salmonella typhi	57%	95%
Q7CEG6	Brucella suis biovar 1 (strain 1330)	54%	93%
Q7CQ01	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	57%	95%
Q7CU92	Agrobacterium fabrum (strain C58 / ATCC 33970)	58%	93%
Q7F9I1	Oryza sativa subsp. japonica	45%	89%
Q7M9X4	Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)	51%	95%
Q7MNK1	Vibrio vulnificus (strain YJ016)	53%	95%
Q7MVE7	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)	49%	95%
Q7N788	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	57%	95%
Q7NAZ3	Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))	46%	100%
Q7NFE9	Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)	54%	94%
Q7NWN7	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	55%	95%
Q7U3T3	Parasynechococcus marenigrum (strain WH8102)	48%	91%
Q7U637	Parasynechococcus marenigrum (strain WH8102)	52%	95%
Q7UBW5	Shigella flexneri	57%	95%
Q7UM33	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	50%	93%
Q7V2A3	Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)	48%	95%
Q7V8B1	Prochlorococcus marinus (strain MIT 9313)	54%	94%
Q7VBL0	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	52%	95%
Q7VJY3	Helicobacter hepaticus (strain ATCC 51449 / 3B1)	50%	95%
Q7VNH1	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	56%	95%
Q7VQF3	Blochmannia floridanus	50%	94%
Q7VYV6	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	53%	94%
Q7W9E6	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	54%	94%
Q7WHB6	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	53%	94%
Q7WSY8	Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)	54%	94%
Q7X2S8	Meiothermus ruber	55%	96%
Q7XL03	Oryza sativa subsp. japonica	43%	87%
Q81GM5	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	52%	94%
Q81TT4	Bacillus anthracis	51%	94%
Q822Q4	Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC)	51%	95%
Q826F2	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	52%	93%
Q82EU9	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	52%	94%
Q82SD8	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	55%	95%
Q831Y7	Enterococcus faecalis (strain ATCC 700802 / V583)	54%	94%
Q83F55	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	58%	95%
Q83FI1	Tropheryma whipplei (strain Twist)	50%	100%
Q83N78	Tropheryma whipplei (strain TW08/27)	50%	100%
Q87AX8	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	56%	95%
Q87S63	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	54%	95%
Q889C2	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	55%	96%
Q88Q71	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	55%	96%
Q88VX7	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	53%	94%
Q898C7	Clostridium tetani (strain Massachusetts / E88)	51%	94%
Q89UL2	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	56%	93%
Q89YY3	Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)	54%	95%
Q8CJV9	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	54%	94%
Q8CPT5	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	50%	94%
Q8CQ88	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	46%	100%
Q8DEV2	Vibrio vulnificus (strain CMCP6)	53%	95%
Q8DG71	Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)	51%	92%
Q8DJ40	Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)	53%	94%
Q8DTC7	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	45%	95%
Q8EBE6	Shewanella oneidensis (strain MR-1)	56%	95%
Q8EU05	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	47%	100%
Q8EW28	Malacoplasma penetrans (strain HF-2)	44%	100%
Q8F509	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	51%	95%
Q8FM94	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	54%	96%
Q8G4X4	Bifidobacterium longum (strain NCC 2705)	52%	92%
Q8NUR7	Staphylococcus aureus (strain MW2)	40%	100%
Q8NXE7	Staphylococcus aureus (strain MW2)	52%	94%
Q8NXY8	Staphylococcus aureus (strain MW2)	47%	100%
Q8P6A0	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	56%	95%
Q8PHQ4	Xanthomonas axonopodis pv. citri (strain 306)	55%	95%
Q8RHQ8	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	50%	95%
Q8VYJ7	Arabidopsis thaliana	53%	85%
Q8XKG8	Clostridium perfringens (strain 13 / Type A)	52%	94%
Q8XZR0	Ralstonia solanacearum (strain GMI1000)	54%	95%
Q8Y570	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	53%	94%
Q8YJ91	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	54%	93%
Q8YM56	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	53%	94%
Q8YUL9	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	51%	93%
Q929G7	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	53%	94%
Q92JK8	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	55%	95%
Q92MK7	Rhizobium meliloti (strain 1021)	56%	94%
Q96UX5	Candida albicans (strain SC5314 / ATCC MYA-2876)	51%	100%
Q97KG0	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	51%	94%
Q98G96	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	57%	94%
Q99R88	Staphylococcus aureus (strain Mu50 / ATCC 700699)	40%	100%
Q99VB5	Staphylococcus aureus (strain Mu50 / ATCC 700699)	52%	94%
Q99W78	Staphylococcus aureus (strain Mu50 / ATCC 700699)	47%	100%
Q9A9T4	Caulobacter vibrioides (strain ATCC 19089 / CB15)	58%	95%
Q9CB26	Mycobacterium leprae (strain TN)	53%	96%
Q9CFF3	Lactococcus lactis subsp. lactis (strain IL1403)	54%	94%
Q9CI09	Lactococcus lactis subsp. lactis (strain IL1403)	42%	100%
Q9CKC0	Pasteurella multocida (strain Pm70)	56%	96%
Q9F746	Yersinia enterocolitica	40%	92%
Q9FI56	Arabidopsis thaliana	45%	88%
Q9HVN5	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	55%	96%
Q9I742	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	39%	91%
Q9JTP9	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	55%	95%
Q9JYQ8	Neisseria meningitidis serogroup B (strain MC58)	55%	95%
Q9KU18	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	55%	95%
Q9LF37	Arabidopsis thaliana	50%	84%
Q9PGC1	Xylella fastidiosa (strain 9a5c)	56%	95%
Q9PI02	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	49%	95%
Q9PKA8	Chlamydia muridarum (strain MoPn / Nigg)	45%	94%
Q9PKS5	Chlamydia muridarum (strain MoPn / Nigg)	51%	94%
Q9RA63	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	55%	96%
Q9RVI3	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	53%	96%
Q9SXJ7	Arabidopsis thaliana	46%	86%
Q9TM05	Cyanidium caldarium	46%	96%
Q9Z6E4	Streptomyces albus G	52%	95%
Q9Z8A6	Chlamydia pneumoniae	44%	97%
Q9ZEA9	Rickettsia prowazekii (strain Madrid E)	55%	95%
Q9ZMH1	Helicobacter pylori (strain J99 / ATCC 700824)	49%	95%
V5AQ73	Trypanosoma cruzi	81%	100%
V5AYJ4	Trypanosoma cruzi	50%	93%