Acetylornithine_deacetylase-like_protein/GeneDB:L mjF.31.1810

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

acetylornithine deacetylase-like protein

Species:

Leishmania donovani

UniProt:

A0A0R6YB63_LEIDO

TriTrypDb:

LdBPK_311840.1 , LdCL_310025600 , LDHU3_31.3180

Length:

101

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A0R6YB63

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A0R6YB63

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	1
GO:0006520	amino acid metabolic process	3	1
GO:0006525	arginine metabolic process	6	1
GO:0006526	arginine biosynthetic process	7	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0008652	amino acid biosynthetic process	4	1
GO:0009058	biosynthetic process	2	1
GO:0009064	glutamine family amino acid metabolic process	5	1
GO:0009084	glutamine family amino acid biosynthetic process	6	1
GO:0009987	cellular process	1	1
GO:0016053	organic acid biosynthetic process	4	1
GO:0019752	carboxylic acid metabolic process	5	1
GO:0043436	oxoacid metabolic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044281	small molecule metabolic process	2	1
GO:0044283	small molecule biosynthetic process	3	1
GO:0046394	carboxylic acid biosynthetic process	5	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1901605	alpha-amino acid metabolic process	4	1
GO:1901607	alpha-amino acid biosynthetic process	5	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0008777	acetylornithine deacetylase activity	4	1
GO:0016787	hydrolase activity	2	2
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4	1
GO:0019213	deacetylase activity	3	1
GO:0004180	carboxypeptidase activity	5	1
GO:0008233	peptidase activity	3	1
GO:0008238	exopeptidase activity	4	1
GO:0140096	catalytic activity, acting on a protein	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	18	20	PF00675	0.255
CLV_NRD_NRD_1	95	97	PF00675	0.349
CLV_PCSK_KEX2_1	95	97	PF00082	0.349
CLV_PCSK_SKI1_1	2	6	PF00082	0.444
DEG_Nend_UBRbox_1	1	4	PF02207	0.396
DOC_MAPK_gen_1	19	28	PF00069	0.293
DOC_USP7_MATH_1	27	31	PF00917	0.306
LIG_14-3-3_CanoR_1	2	10	PF00244	0.431
LIG_14-3-3_CanoR_1	23	27	PF00244	0.334
LIG_14-3-3_CanoR_1	61	66	PF00244	0.323
LIG_FHA_1	70	76	PF00498	0.278
LIG_FHA_2	55	61	PF00498	0.296
LIG_LIR_Apic_2	60	66	PF02991	0.240
LIG_SH2_CRK	63	67	PF00017	0.255
LIG_SH2_STAP1	38	42	PF00017	0.278
LIG_SH2_STAT3	38	41	PF00017	0.323
LIG_SH3_3	91	97	PF00018	0.419
LIG_TRAF2_1	57	60	PF00917	0.323
MOD_CK2_1	54	60	PF00069	0.323
MOD_N-GLC_1	61	66	PF02516	0.323
MOD_NEK2_1	28	33	PF00069	0.323
MOD_NEK2_1	51	56	PF00069	0.277
MOD_PKA_2	22	28	PF00069	0.255
TRG_ER_diArg_1	94	96	PF00400	0.358

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NDP9	Trypanosomatidae	39%	70%
A4I6W2	Leishmania infantum	100%	100%
Q4Q681	Leishmania major	85%	100%