Sucrose-phosphate_synthase-like_protein/GeneDB:Lm jF.16.0950

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

sucrose-phosphate synthase-like protein

Species:

Leishmania donovani

UniProt:

A0A0R6YAV9_LEIDO

TriTrypDb:

LdBPK_160960.1 , LdCL_160014800 , LDHU3_16.1150

Length:

464

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A0R6YAV9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A0R6YAV9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0008194	UDP-glycosyltransferase activity	4	6
GO:0016740	transferase activity	2	8
GO:0016757	glycosyltransferase activity	3	8
GO:0016758	hexosyltransferase activity	4	6
GO:0035251	UDP-glucosyltransferase activity	5	6
GO:0046524	sucrose-phosphate synthase activity	6	6
GO:0046527	glucosyltransferase activity	5	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	140	142	PF00675	0.488
CLV_NRD_NRD_1	324	326	PF00675	0.464
CLV_PCSK_KEX2_1	117	119	PF00082	0.524
CLV_PCSK_KEX2_1	140	142	PF00082	0.490
CLV_PCSK_KEX2_1	293	295	PF00082	0.400
CLV_PCSK_KEX2_1	310	312	PF00082	0.522
CLV_PCSK_KEX2_1	83	85	PF00082	0.580
CLV_PCSK_PC1ET2_1	117	119	PF00082	0.524
CLV_PCSK_PC1ET2_1	293	295	PF00082	0.400
CLV_PCSK_PC1ET2_1	310	312	PF00082	0.599
CLV_PCSK_PC1ET2_1	83	85	PF00082	0.580
CLV_PCSK_SKI1_1	185	189	PF00082	0.519
CLV_PCSK_SKI1_1	310	314	PF00082	0.464
CLV_PCSK_SKI1_1	422	426	PF00082	0.476
DOC_CKS1_1	53	58	PF01111	0.594
DOC_MAPK_DCC_7	141	151	PF00069	0.495
DOC_MAPK_DCC_7	63	73	PF00069	0.555
DOC_MAPK_gen_1	114	123	PF00069	0.515
DOC_MAPK_gen_1	307	317	PF00069	0.550
DOC_MAPK_HePTP_8	111	123	PF00069	0.512
DOC_MAPK_MEF2A_6	114	123	PF00069	0.513
DOC_MAPK_MEF2A_6	310	317	PF00069	0.476
DOC_MAPK_NFAT4_5	310	318	PF00069	0.476
DOC_PP1_RVXF_1	279	286	PF00149	0.400
DOC_PP4_FxxP_1	128	131	PF00568	0.428
DOC_PP4_FxxP_1	343	346	PF00568	0.400
DOC_USP7_MATH_1	35	39	PF00917	0.492
DOC_USP7_MATH_1	359	363	PF00917	0.456
DOC_USP7_MATH_1	79	83	PF00917	0.592
DOC_WW_Pin1_4	220	225	PF00397	0.507
DOC_WW_Pin1_4	380	385	PF00397	0.400
DOC_WW_Pin1_4	52	57	PF00397	0.575
LIG_14-3-3_CanoR_1	265	273	PF00244	0.520
LIG_14-3-3_CanoR_1	311	316	PF00244	0.404
LIG_14-3-3_CanoR_1	84	89	PF00244	0.520
LIG_Actin_WH2_2	324	341	PF00022	0.400
LIG_BIR_II_1	1	5	PF00653	0.548
LIG_BRCT_BRCA1_1	17	21	PF00533	0.579
LIG_BRCT_BRCA1_1	194	198	PF00533	0.503
LIG_Clathr_ClatBox_1	373	377	PF01394	0.400
LIG_deltaCOP1_diTrp_1	4	8	PF00928	0.499
LIG_FHA_1	103	109	PF00498	0.480
LIG_FHA_1	182	188	PF00498	0.540
LIG_FHA_1	189	195	PF00498	0.551
LIG_FHA_1	322	328	PF00498	0.593
LIG_FHA_1	333	339	PF00498	0.428
LIG_FHA_1	381	387	PF00498	0.400
LIG_FHA_2	355	361	PF00498	0.400
LIG_FHA_2	407	413	PF00498	0.484
LIG_FHA_2	430	436	PF00498	0.623
LIG_FHA_2	53	59	PF00498	0.594
LIG_FHA_2	87	93	PF00498	0.536
LIG_LIR_Apic_2	340	346	PF02991	0.464
LIG_LIR_Gen_1	207	216	PF02991	0.564
LIG_LIR_Gen_1	330	338	PF02991	0.476
LIG_LIR_Gen_1	4	10	PF02991	0.440
LIG_LIR_Gen_1	415	426	PF02991	0.476
LIG_LIR_Gen_1	82	93	PF02991	0.524
LIG_LIR_Nem_3	105	110	PF02991	0.503
LIG_LIR_Nem_3	207	211	PF02991	0.506
LIG_LIR_Nem_3	330	336	PF02991	0.484
LIG_LIR_Nem_3	368	374	PF02991	0.400
LIG_LIR_Nem_3	4	8	PF02991	0.442
LIG_LIR_Nem_3	415	421	PF02991	0.476
LIG_LIR_Nem_3	60	65	PF02991	0.488
LIG_Pex14_2	208	212	PF04695	0.454
LIG_Pex14_2	285	289	PF04695	0.400
LIG_Pex14_2	371	375	PF04695	0.400
LIG_SH2_CRK	227	231	PF00017	0.524
LIG_SH2_CRK	279	283	PF00017	0.460
LIG_SH2_CRK	333	337	PF00017	0.461
LIG_SH2_CRK	418	422	PF00017	0.460
LIG_SH2_GRB2like	163	166	PF00017	0.463
LIG_SH2_NCK_1	356	360	PF00017	0.476
LIG_SH2_SRC	65	68	PF00017	0.561
LIG_SH2_STAP1	163	167	PF00017	0.530
LIG_SH2_STAP1	279	283	PF00017	0.460
LIG_SH2_STAT5	110	113	PF00017	0.516
LIG_SH2_STAT5	328	331	PF00017	0.411
LIG_SH2_STAT5	356	359	PF00017	0.460
LIG_SH2_STAT5	96	99	PF00017	0.535
LIG_SH3_1	210	216	PF00018	0.530
LIG_SH3_2	171	176	PF14604	0.562
LIG_SH3_3	144	150	PF00018	0.488
LIG_SH3_3	168	174	PF00018	0.570
LIG_SH3_3	197	203	PF00018	0.523
LIG_SH3_3	210	216	PF00018	0.475
LIG_SH3_3	228	234	PF00018	0.395
LIG_TRAF2_1	89	92	PF00917	0.524
LIG_TRFH_1	212	216	PF08558	0.543
LIG_TRFH_1	342	346	PF08558	0.400
LIG_UBA3_1	211	217	PF00899	0.434
MOD_CDK_SPxxK_3	52	59	PF00069	0.572
MOD_CK1_1	321	327	PF00069	0.424
MOD_CK1_1	446	452	PF00069	0.473
MOD_CK2_1	300	306	PF00069	0.460
MOD_CK2_1	363	369	PF00069	0.400
MOD_CK2_1	406	412	PF00069	0.460
MOD_CK2_1	446	452	PF00069	0.497
MOD_CK2_1	86	92	PF00069	0.516
MOD_Cter_Amidation	115	118	PF01082	0.541
MOD_GlcNHglycan	17	20	PF01048	0.601
MOD_GlcNHglycan	194	197	PF01048	0.454
MOD_GlcNHglycan	200	203	PF01048	0.518
MOD_GlcNHglycan	24	27	PF01048	0.543
MOD_GlcNHglycan	389	392	PF01048	0.400
MOD_GSK3_1	188	195	PF00069	0.554
MOD_GSK3_1	255	262	PF00069	0.516
MOD_GSK3_1	359	366	PF00069	0.509
MOD_GSK3_1	43	50	PF00069	0.452
MOD_NEK2_1	188	193	PF00069	0.511
MOD_NEK2_1	198	203	PF00069	0.537
MOD_NEK2_1	255	260	PF00069	0.547
MOD_NEK2_1	338	343	PF00069	0.460
MOD_NEK2_1	445	450	PF00069	0.484
MOD_NEK2_1	457	462	PF00069	0.569
MOD_NEK2_2	359	364	PF00069	0.428
MOD_PIKK_1	255	261	PF00454	0.650
MOD_PIKK_1	318	324	PF00454	0.476
MOD_PIKK_1	345	351	PF00454	0.460
MOD_PIKK_1	446	452	PF00454	0.505
MOD_PK_1	294	300	PF00069	0.451
MOD_PKA_1	443	449	PF00069	0.525
MOD_PKA_2	181	187	PF00069	0.540
MOD_PKA_2	271	277	PF00069	0.443
MOD_Plk_1	255	261	PF00069	0.567
MOD_Plk_1	359	365	PF00069	0.476
MOD_Plk_1	91	97	PF00069	0.548
MOD_Plk_2-3	92	98	PF00069	0.544
MOD_Plk_4	294	300	PF00069	0.467
MOD_Plk_4	311	317	PF00069	0.400
MOD_Plk_4	338	344	PF00069	0.444
MOD_Plk_4	359	365	PF00069	0.479
MOD_Plk_4	43	49	PF00069	0.501
MOD_ProDKin_1	220	226	PF00069	0.505
MOD_ProDKin_1	380	386	PF00069	0.400
MOD_ProDKin_1	52	58	PF00069	0.580
MOD_SUMO_rev_2	303	312	PF00179	0.476
MOD_SUMO_rev_2	427	432	PF00179	0.460
TRG_DiLeu_BaEn_1	369	374	PF01217	0.400
TRG_DiLeu_BaEn_1	400	405	PF01217	0.452
TRG_DiLeu_BaEn_2	102	108	PF01217	0.510
TRG_ENDOCYTIC_2	178	181	PF00928	0.459
TRG_ENDOCYTIC_2	227	230	PF00928	0.525
TRG_ENDOCYTIC_2	252	255	PF00928	0.485
TRG_ENDOCYTIC_2	279	282	PF00928	0.464
TRG_ENDOCYTIC_2	328	331	PF00928	0.400
TRG_ENDOCYTIC_2	333	336	PF00928	0.400
TRG_ENDOCYTIC_2	418	421	PF00928	0.460
TRG_ER_diArg_1	140	142	PF00400	0.552
TRG_NLS_MonoExtC_3	429	435	PF00514	0.425
TRG_Pf-PMV_PEXEL_1	325	330	PF00026	0.476

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILL5	Leptomonas seymouri	80%	100%
A0A0S4JKT8	Bodo saltans	47%	85%
A4H8L9	Leishmania braziliensis	91%	100%
A4HWZ0	Leishmania infantum	100%	100%
E9AQQ4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QES5	Leishmania major	97%	100%