LeishMANIAdb
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Rhodanese-like_domain_containing_protein_putative /Pfam:PF00581

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Rhodanese-like_domain_containing_protein_putative /Pfam:PF00581
Gene product:
rhodanese-like domain containing protein, putative
Species:
Leishmania donovani
UniProt:
A0A0R6XWV6_LEIDO
TriTrypDb:
LdBPK_331040.1 , LdCL_330016500 , LDHU3_33.1610
Length:
143

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A0R6XWV6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A0R6XWV6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 128 132 PF00082 0.391
DEG_APCC_DBOX_1 127 135 PF00400 0.591
DOC_MAPK_MEF2A_6 124 131 PF00069 0.591
DOC_PP4_FxxP_1 59 62 PF00568 0.591
DOC_WW_Pin1_4 35 40 PF00397 0.571
DOC_WW_Pin1_4 96 101 PF00397 0.549
LIG_BIR_II_1 1 5 PF00653 0.706
LIG_LIR_Apic_2 58 62 PF02991 0.605
LIG_LIR_Gen_1 136 143 PF02991 0.653
LIG_LIR_Gen_1 54 62 PF02991 0.591
LIG_LIR_Gen_1 71 81 PF02991 0.591
LIG_LIR_Nem_3 136 140 PF02991 0.591
LIG_LIR_Nem_3 54 59 PF02991 0.591
LIG_LIR_Nem_3 71 77 PF02991 0.591
LIG_PDZ_Class_2 138 143 PF00595 0.569
LIG_Pex14_1 137 141 PF04695 0.656
LIG_SH2_GRB2like 110 113 PF00017 0.591
LIG_SH2_STAT5 110 113 PF00017 0.591
LIG_SH2_STAT5 135 138 PF00017 0.676
LIG_SUMO_SIM_anti_2 43 49 PF11976 0.591
LIG_SUMO_SIM_par_1 43 49 PF11976 0.551
LIG_TRAF2_1 28 31 PF00917 0.591
LIG_TRAF2_1 68 71 PF00917 0.591
LIG_WRC_WIRS_1 56 61 PF05994 0.591
MOD_CK1_1 96 102 PF00069 0.549
MOD_CK2_1 25 31 PF00069 0.435
MOD_GlcNHglycan 21 24 PF01048 0.619
MOD_GlcNHglycan 26 30 PF01048 0.405
MOD_GlcNHglycan 95 98 PF01048 0.366
MOD_PIKK_1 135 141 PF00454 0.572
MOD_PKA_2 6 12 PF00069 0.695
MOD_Plk_4 40 46 PF00069 0.653
MOD_ProDKin_1 35 41 PF00069 0.571
MOD_ProDKin_1 96 102 PF00069 0.549
TRG_DiLeu_BaEn_3 30 36 PF01217 0.543
TRG_ENDOCYTIC_2 56 59 PF00928 0.693

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1ILL9 Leptomonas seymouri 55% 100%
A0A0S4J1P4 Bodo saltans 31% 78%
A4I8W3 Leishmania infantum 98% 99%
E9B3T2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4Q492 Leishmania major 92% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS